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List of co-cited articles
1497 articles co-cited >1



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  Times     Co-cited
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A role for the MLL fusion partner ENL in transcriptional elongation and chromatin modification.
Dorothee Mueller, Christian Bach, Deniz Zeisig, Maria-Paz Garcia-Cuellar, Sara Monroe, Arun Sreekumar, Rong Zhou, Alexey Nesvizhskii, Arul Chinnaiyan, Jay L Hess,[...]. Blood 2007
273
54

hDOT1L links histone methylation to leukemogenesis.
Yuki Okada, Qin Feng, Yihui Lin, Qi Jiang, Yaqiang Li, Vernon M Coffield, Lishan Su, Guoliang Xu, Yi Zhang. Cell 2005
571
51

Potent inhibition of DOT1L as treatment of MLL-fusion leukemia.
Scott R Daigle, Edward J Olhava, Carly A Therkelsen, Aravind Basavapathruni, Lei Jin, P Ann Boriack-Sjodin, Christina J Allain, Christine R Klaus, Alejandra Raimondi, Margaret Porter Scott,[...]. Blood 2013
443
46

H3K79 methylation profiles define murine and human MLL-AF4 leukemias.
Andrei V Krivtsov, Zhaohui Feng, Madeleine E Lemieux, Joerg Faber, Sridhar Vempati, Amit U Sinha, Xiaobo Xia, Jonathan Jesneck, Adrian P Bracken, Lewis B Silverman,[...]. Cancer Cell 2008
385
43

MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.
Kathrin M Bernt, Nan Zhu, Amit U Sinha, Sridhar Vempati, Joerg Faber, Andrei V Krivtsov, Zhaohui Feng, Natalie Punt, Amanda Daigle, Lars Bullinger,[...]. Cancer Cell 2011
576
40

Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor.
Scott R Daigle, Edward J Olhava, Carly A Therkelsen, Christina R Majer, Christopher J Sneeringer, Jeffrey Song, L Danielle Johnston, Margaret Porter Scott, Jesse J Smith, Yonghong Xiao,[...]. Cancer Cell 2011
629
39

A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription.
Akihiko Yokoyama, Min Lin, Alpana Naresh, Issay Kitabayashi, Michael L Cleary. Cancer Cell 2010
245
38

AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia.
Chengqi Lin, Edwin R Smith, Hidehisa Takahashi, Ka Chun Lai, Skylar Martin-Brown, Laurence Florens, Michael P Washburn, Joan W Conaway, Ronald C Conaway, Ali Shilatifard. Mol Cell 2010
386
36

Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain.
Qin Feng, Hengbin Wang, Huck Hui Ng, Hediye Erdjument-Bromage, Paul Tempst, Kevin Struhl, Yi Zhang. Curr Biol 2002
550
35

MLL translocations, histone modifications and leukaemia stem-cell development.
Andrei V Krivtsov, Scott A Armstrong. Nat Rev Cancer 2007
775
32

DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells.
David J Steger, Martina I Lefterova, Lei Ying, Aaron J Stonestrom, Michael Schupp, David Zhuo, Adam L Vakoc, Ja-Eun Kim, Junjie Chen, Mitchell A Lazar,[...]. Mol Cell Biol 2008
310
30

Misguided transcriptional elongation causes mixed lineage leukemia.
Dorothee Mueller, María-Paz García-Cuéllar, Christian Bach, Sebastian Buhl, Emanuel Maethner, Robert K Slany. PLoS Biol 2009
145
29

Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors.
Wenyu Yu, Emma J Chory, Amy K Wernimont, Wolfram Tempel, Alex Scopton, Alexander Federation, Jason J Marineau, Jun Qi, Dalia Barsyte-Lovejoy, Joanna Yi,[...]. Nat Commun 2012
181
28

Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom).
Man Mohan, Hans-Martin Herz, Yoh-Hei Takahashi, Chengqi Lin, Ka Chun Lai, Ying Zhang, Michael P Washburn, Laurence Florens, Ali Shilatifard. Genes Dev 2010
201
27

Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes.
Debabrata Biswas, Thomas A Milne, Venkatesha Basrur, Jaehoon Kim, Kojo S J Elenitoba-Johnson, C David Allis, Robert G Roeder. Proc Natl Acad Sci U S A 2011
120
27

DOT1L, the H3K79 methyltransferase, is required for MLL-AF9-mediated leukemogenesis.
Anh Tram Nguyen, Olena Taranova, Jin He, Yi Zhang. Blood 2011
174
25

MLL targets SET domain methyltransferase activity to Hox gene promoters.
Thomas A Milne, Scott D Briggs, Hugh W Brock, Mary Ellen Martin, Denise Gibbs, C David Allis, Jay L Hess. Mol Cell 2002
775
24

The diverse functions of Dot1 and H3K79 methylation.
Anh Tram Nguyen, Yi Zhang. Genes Dev 2011
355
23

The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure.
Brendan Jones, Hui Su, Audesh Bhat, Hong Lei, Jeffrey Bajko, Sarah Hevi, Gretchen A Baltus, Shilpa Kadam, Huili Zhai, Reginald Valdez,[...]. PLoS Genet 2008
229
22

Dot1a-AF9 complex mediates histone H3 Lys-79 hypermethylation and repression of ENaCalpha in an aldosterone-sensitive manner.
Wenzheng Zhang, Xuefeng Xia, Mary Rose Reisenauer, Charles S Hemenway, Bruce C Kone. J Biol Chem 2006
128
21

Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l.
Aniruddha J Deshpande, Liying Chen, Maurizio Fazio, Amit U Sinha, Kathrin M Bernt, Deepti Banka, Stuart Dias, Jenny Chang, Edward J Olhava, Scott R Daigle,[...]. Blood 2013
115
21

DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.
Chun-Wei Chen, Richard P Koche, Amit U Sinha, Aniruddha J Deshpande, Nan Zhu, Rowena Eng, John G Doench, Haiming Xu, Scott H Chu, Jun Qi,[...]. Nat Med 2015
133
19

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia.
Mark A Dawson, Rab K Prinjha, Antje Dittmann, George Giotopoulos, Marcus Bantscheff, Wai-In Chan, Samuel C Robson, Chun-wa Chung, Carsten Hopf, Mikhail M Savitski,[...]. Nature 2011
18

Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia.
Matthew G Guenther, Lee N Lawton, Tatiana Rozovskaia, Garrett M Frampton, Stuart S Levine, Thomas L Volkert, Carlo M Croce, Tatsuya Nakamura, Eli Canaani, Richard A Young. Genes Dev 2008
197
18

Dot1p modulates silencing in yeast by methylation of the nucleosome core.
Fred van Leeuwen, Philip R Gafken, Daniel E Gottschling. Cell 2002
605
18

Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation.
Stephanie Y Jo, Eric M Granowicz, Ivan Maillard, Dafydd Thomas, Jay L Hess. Blood 2011
146
18

ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation.
Tatsuya Nakamura, Toshiki Mori, Shinichiro Tada, Wladyslaw Krajewski, Tanya Rozovskaia, Richard Wassell, Garrett Dubois, Alexander Mazo, Carlo M Croce, Eli Canaani. Mol Cell 2002
549
17


The pathogenesis of mixed-lineage leukemia.
Andrew G Muntean, Jay L Hess. Annu Rev Pathol 2012
215
16

Abrogation of MLL-AF10 and CALM-AF10-mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l.
L Chen, A J Deshpande, D Banka, K M Bernt, S Dias, C Buske, E J Olhava, S R Daigle, V M Richon, R M Pollock,[...]. Leukemia 2013
97
16

The MLL recombinome of acute leukemias in 2013.
C Meyer, J Hofmann, T Burmeister, D Gröger, T S Park, M Emerenciano, M Pombo de Oliveira, A Renneville, P Villarese, E Macintyre,[...]. Leukemia 2013
297
16

AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes.
Aniruddha J Deshpande, Anagha Deshpande, Amit U Sinha, Liying Chen, Jenny Chang, Ali Cihan, Maurizio Fazio, Chun-Wei Chen, Nan Zhu, Richard Koche,[...]. Cancer Cell 2014
105
16

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations.
Michael T McCabe, Heidi M Ott, Gopinath Ganji, Susan Korenchuk, Christine Thompson, Glenn S Van Aller, Yan Liu, Alan P Graves, Anthony Della Pietra, Elsie Diaz,[...]. Nature 2012
15

Conformational adaptation drives potent, selective and durable inhibition of the human protein methyltransferase DOT1L.
Aravind Basavapathruni, Lei Jin, Scott R Daigle, Christina R A Majer, Carly A Therkelsen, Tim J Wigle, Kevin W Kuntz, Richard Chesworth, Roy M Pollock, Margaret P Scott,[...]. Chem Biol Drug Des 2012
92
16

MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia.
Scott A Armstrong, Jane E Staunton, Lewis B Silverman, Rob Pieters, Monique L den Boer, Mark D Minden, Stephen E Sallan, Eric S Lander, Todd R Golub, Stanley J Korsmeyer. Nat Genet 2002
15

Controlling the elongation phase of transcription with P-TEFb.
B Matija Peterlin, David H Price. Mol Cell 2006
800
15

MLL-AF9-induced leukemogenesis requires coexpression of the wild-type Mll allele.
Austin T Thiel, Peter Blessington, Tao Zou, Danielle Feather, Xinjiang Wu, Jizhou Yan, Hui Zhang, Zuguo Liu, Patricia Ernst, Gary A Koretzky,[...]. Cancer Cell 2010
174
15

The AF4.MLL fusion protein is capable of inducing ALL in mice without requirement of MLL.AF4.
Adelheid Bursen, Karen Schwabe, Brigitte Rüster, Reinhard Henschler, Martin Ruthardt, Theo Dingermann, Rolf Marschalek. Blood 2010
115
15

The MLL recombinome of acute leukemias in 2017.
C Meyer, T Burmeister, D Gröger, G Tsaur, L Fechina, A Renneville, R Sutton, N C Venn, M Emerenciano, M S Pombo-de-Oliveira,[...]. Leukemia 2018
277
15

High-resolution profiling of histone methylations in the human genome.
Artem Barski, Suresh Cuddapah, Kairong Cui, Tae-Young Roh, Dustin E Schones, Zhibin Wang, Gang Wei, Iouri Chepelev, Keji Zhao. Cell 2007
14


AF9 YEATS domain links histone acetylation to DOT1L-mediated H3K79 methylation.
Yuanyuan Li, Hong Wen, Yuanxin Xi, Kaori Tanaka, Haibo Wang, Danni Peng, Yongfeng Ren, Qihuang Jin, Sharon Y R Dent, Wei Li,[...]. Cell 2014
194
14

MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia.
Sara C Monroe, Stephanie Y Jo, Daniel S Sanders, Venkatesha Basrur, Kojo S Elenitoba-Johnson, Robert K Slany, Jay L Hess. Exp Hematol 2011
59
22

A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells.
Sarah K Knutson, Tim J Wigle, Natalie M Warholic, Christopher J Sneeringer, Christina J Allain, Christine R Klaus, Joelle D Sacks, Alejandra Raimondi, Christina R Majer, Jeffrey Song,[...]. Nat Chem Biol 2012
536
13

Selective inhibitors of histone methyltransferase DOT1L: design, synthesis, and crystallographic studies.
Yuan Yao, Pinhong Chen, Jiasheng Diao, Gang Cheng, Lisheng Deng, Justin L Anglin, B V Venkataram Prasad, Yongcheng Song. J Am Chem Soc 2011
114
13

Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.
Andrei V Krivtsov, David Twomey, Zhaohui Feng, Matthew C Stubbs, Yingzi Wang, Joerg Faber, Jason E Levine, Jing Wang, William C Hahn, D Gary Gilliland,[...]. Nature 2006
13

The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis.
Akihiko Yokoyama, Tim C P Somervaille, Kevin S Smith, Orit Rozenblatt-Rosen, Matthew Meyerson, Michael L Cleary. Cell 2005
365
13

Synthesis and structure-activity relationship investigation of adenosine-containing inhibitors of histone methyltransferase DOT1L.
Justin L Anglin, Lisheng Deng, Yuan Yao, Guobin Cai, Zhen Liu, Hong Jiang, Gang Cheng, Pinhong Chen, Shuo Dong, Yongcheng Song. J Med Chem 2012
63
20

Histone H3 lysine 79 methyltransferase Dot1 is required for immortalization by MLL oncogenes.
Ming-Jin Chang, Hongyu Wu, Nicholas J Achille, Mary Rose Reisenauer, Chau-Wen Chou, Nancy J Zeleznik-Le, Charles S Hemenway, Wenzheng Zhang. Cancer Res 2010
121
13

The eleven-nineteen-leukemia protein ENL connects nuclear MLL fusion partners with chromatin.
Deniz T Zeisig, Claudia B Bittner, Bernd B Zeisig, Maria-Paz García-Cuéllar, Jay L Hess, Robert K Slany. Oncogene 2005
83
15


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.