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Times Cited: 626
Times Cited: 626
Times Cited
Times Co-cited
Similarity
Variants in nicotinic receptors and risk for nicotine dependence.
Laura Jean Bierut, Jerry A Stitzel, Jen C Wang, Anthony L Hinrichs, Richard A Grucza, Xiaoling Xuei, Nancy L Saccone, Scott F Saccone, Sarah Bertelsen, Louis Fox,[...]. Am J Psychiatry 2008
Laura Jean Bierut, Jerry A Stitzel, Jen C Wang, Anthony L Hinrichs, Richard A Grucza, Xiaoling Xuei, Nancy L Saccone, Scott F Saccone, Sarah Bertelsen, Louis Fox,[...]. Am J Psychiatry 2008
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A variant associated with nicotine dependence, lung cancer and peripheral arterial disease.
Thorgeir E Thorgeirsson, Frank Geller, Patrick Sulem, Thorunn Rafnar, Anna Wiste, Kristinn P Magnusson, Andrei Manolescu, Gudmar Thorleifsson, Hreinn Stefansson, Andres Ingason,[...]. Nature 2008
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33
Genome-wide meta-analyses identify multiple loci associated with smoking behavior.
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31
Habenular α5 nicotinic receptor subunit signalling controls nicotine intake.
Christie D Fowler, Qun Lu, Paul M Johnson, Michael J Marks, Paul J Kenny. Nature 2011
Christie D Fowler, Qun Lu, Paul M Johnson, Michael J Marks, Paul J Kenny. Nature 2011
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Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.
Thorgeir E Thorgeirsson, Daniel F Gudbjartsson, Ida Surakka, Jacqueline M Vink, Najaf Amin, Frank Geller, Patrick Sulem, Thorunn Rafnar, Tõnu Esko, Stefan Walter,[...]. Nat Genet 2010
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26
Novel genes identified in a high-density genome wide association study for nicotine dependence.
Laura Jean Bierut, Pamela A F Madden, Naomi Breslau, Eric O Johnson, Dorothy Hatsukami, Ovide F Pomerleau, Gary E Swan, Joni Rutter, Sarah Bertelsen, Louis Fox,[...]. Hum Mol Genet 2007
Laura Jean Bierut, Pamela A F Madden, Naomi Breslau, Eric O Johnson, Dorothy Hatsukami, Ovide F Pomerleau, Gary E Swan, Joni Rutter, Sarah Bertelsen, Louis Fox,[...]. Hum Mol Genet 2007
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Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking.
W Berrettini, X Yuan, F Tozzi, K Song, C Francks, H Chilcoat, D Waterworth, P Muglia, V Mooser. Mol Psychiatry 2008
W Berrettini, X Yuan, F Tozzi, K Song, C Francks, H Chilcoat, D Waterworth, P Muglia, V Mooser. Mol Psychiatry 2008
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Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1.
Christopher I Amos, Xifeng Wu, Peter Broderick, Ivan P Gorlov, Jian Gu, Timothy Eisen, Qiong Dong, Qing Zhang, Xiangjun Gu, Jayaram Vijayakrishnan,[...]. Nat Genet 2008
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24
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25.
Rayjean J Hung, James D McKay, Valerie Gaborieau, Paolo Boffetta, Mia Hashibe, David Zaridze, Anush Mukeria, Neonilia Szeszenia-Dabrowska, Jolanta Lissowska, Peter Rudnai,[...]. Nature 2008
Rayjean J Hung, James D McKay, Valerie Gaborieau, Paolo Boffetta, Mia Hashibe, David Zaridze, Anush Mukeria, Neonilia Szeszenia-Dabrowska, Jolanta Lissowska, Peter Rudnai,[...]. Nature 2008
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Acetylcholine receptor (AChR) α5 subunit variant associated with risk for nicotine dependence and lung cancer reduces (α4β2)₂α5 AChR function.
Alexander Kuryatov, Wade Berrettini, Jon Lindstrom. Mol Pharmacol 2011
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Meta-analysis and imputation refines the association of 15q25 with smoking quantity.
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The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.
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Interplay of genetic risk factors (CHRNA5-CHRNA3-CHRNB4) and cessation treatments in smoking cessation success.
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Aversion to nicotine is regulated by the balanced activity of β4 and α5 nicotinic receptor subunits in the medial habenula.
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Nicotinic receptors in the habenulo-interpeduncular system are necessary for nicotine withdrawal in mice.
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Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.
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The Fagerström Test for Nicotine Dependence: a revision of the Fagerström Tolerance Questionnaire.
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CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis--a meta-analysis.
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Nicotinic receptor gene variants influence susceptibility to heavy smoking.
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Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking.
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13
Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.
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12
Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine.
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Role of alpha5 nicotinic acetylcholine receptors in pharmacological and behavioral effects of nicotine in mice.
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12
A CHRNA5 Smoking Risk Variant Decreases the Aversive Effects of Nicotine in Humans.
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Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes.
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12
Nicotine activation of alpha4* receptors: sufficient for reward, tolerance, and sensitization.
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Rodent habenulo-interpeduncular pathway expresses a large variety of uncommon nAChR subtypes, but only the alpha3beta4* and alpha3beta3beta4* subtypes mediate acetylcholine release.
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11
Crucial role of nicotinic α5 subunit variants for Ca2+ fluxes in ventral midbrain neurons.
Miriam Sciaccaluga, Claudia Moriconi, Katiuscia Martinello, Myriam Catalano, Isabel Bermudez, Jerry A Stitzel, Uwe Maskos, Sergio Fucile. FASEB J 2015
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A risk allele for nicotine dependence in CHRNA5 is a protective allele for cocaine dependence.
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10
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Nicotinic acetylcholine receptor variation and response to smoking cessation therapies.
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Genome-wide meta-analyses of smoking behaviors in African Americans.
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Impact of human D398N single nucleotide polymorphism on intracellular calcium response mediated by α3β4α5 nicotinic acetylcholine receptors.
Anne Tammimäki, Penelope Herder, Ping Li, Caroline Esch, James R Laughlin, Gustav Akk, Jerry A Stitzel. Neuropharmacology 2012
Anne Tammimäki, Penelope Herder, Ping Li, Caroline Esch, James R Laughlin, Gustav Akk, Jerry A Stitzel. Neuropharmacology 2012
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Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs.
K J Jackson, B R Martin, J P Changeux, M I Damaj. J Pharmacol Exp Ther 2008
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Crucial role of alpha4 and alpha6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration.
S Pons, L Fattore, G Cossu, S Tolu, E Porcu, J M McIntosh, J P Changeux, U Maskos, W Fratta. J Neurosci 2008
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A Human Polymorphism in CHRNA5 Is Linked to Relapse to Nicotine Seeking in Transgenic Rats.
Benoit Forget, Petra Scholze, Francina Langa, Carole Morel, Stephanie Pons, Sarah Mondoloni, Morgane Besson, Romain Durand-de Cuttoli, Audrey Hay, Ludovic Tricoire,[...]. Curr Biol 2018
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Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals.
Esther H Lips, Valerie Gaborieau, James D McKay, Amelie Chabrier, Rayjean J Hung, Paolo Boffetta, Mia Hashibe, David Zaridze, Neonilia Szeszenia-Dabrowska, Jolanta Lissowska,[...]. Int J Epidemiol 2010
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10
Markers in the 15q24 nicotinic receptor subunit gene cluster (CHRNA5-A3-B4) predict severity of nicotine addiction and response to smoking cessation therapy.
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13
Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence.
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Decreased signs of nicotine withdrawal in mice null for the beta4 nicotinic acetylcholine receptor subunit.
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Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.
Mengzhen Liu, Yu Jiang, Robbee Wedow, Yue Li, David M Brazel, Fang Chen, Gargi Datta, Jose Davila-Velderrain, Daniel McGuire, Chao Tian,[...]. Nat Genet 2019
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A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction.
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8
A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy.
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Smoking cessation pharmacogenetics: analysis of varenicline and bupropion in placebo-controlled clinical trials.
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Medial habenula output circuit mediated by α5 nicotinic receptor-expressing GABAergic neurons in the interpeduncular nucleus.
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8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.