Andrew Hinman, Huai-Hu Chuang, Diana M Bautista, David Julius. Proc Natl Acad Sci U S A 2006
Times Cited: 653
Times Cited: 653
Times Cited
Times Co-cited
Similarity
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines.
Lindsey J Macpherson, Adrienne E Dubin, Michael J Evans, Felix Marr, Peter G Schultz, Benjamin F Cravatt, Ardem Patapoutian. Nature 2007
Lindsey J Macpherson, Adrienne E Dubin, Michael J Evans, Felix Marr, Peter G Schultz, Benjamin F Cravatt, Ardem Patapoutian. Nature 2007
58
Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin.
Michael Bandell, Gina M Story, Sun Wook Hwang, Veena Viswanath, Samer R Eid, Matt J Petrus, Taryn J Earley, Ardem Patapoutian. Neuron 2004
Michael Bandell, Gina M Story, Sun Wook Hwang, Veena Viswanath, Samer R Eid, Matt J Petrus, Taryn J Earley, Ardem Patapoutian. Neuron 2004
46
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1.
Sven-Eric Jordt, Diana M Bautista, Huai-Hu Chuang, David D McKemy, Peter M Zygmunt, Edward D Högestätt, Ian D Meng, David Julius. Nature 2004
Sven-Eric Jordt, Diana M Bautista, Huai-Hu Chuang, David D McKemy, Peter M Zygmunt, Edward D Högestätt, Ian D Meng, David Julius. Nature 2004
38
TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents.
Diana M Bautista, Sven-Eric Jordt, Tetsuro Nikai, Pamela R Tsuruda, Andrew J Read, Jeannie Poblete, Ebenezer N Yamoah, Allan I Basbaum, David Julius. Cell 2006
Diana M Bautista, Sven-Eric Jordt, Tetsuro Nikai, Pamela R Tsuruda, Andrew J Read, Jeannie Poblete, Ebenezer N Yamoah, Allan I Basbaum, David Julius. Cell 2006
37
ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures.
Gina M Story, Andrea M Peier, Alison J Reeve, Samer R Eid, Johannes Mosbacher, Todd R Hricik, Taryn J Earley, Anne C Hergarden, David A Andersson, Sun Wook Hwang,[...]. Cell 2003
Gina M Story, Andrea M Peier, Alison J Reeve, Samer R Eid, Johannes Mosbacher, Todd R Hricik, Taryn J Earley, Anne C Hergarden, David A Andersson, Sun Wook Hwang,[...]. Cell 2003
32
Structure of the TRPA1 ion channel suggests regulatory mechanisms.
Candice E Paulsen, Jean-Paul Armache, Yuan Gao, Yifan Cheng, David Julius. Nature 2015
Candice E Paulsen, Jean-Paul Armache, Yuan Gao, Yifan Cheng, David Julius. Nature 2015
28
Transient receptor potential A1 is a sensory receptor for multiple products of oxidative stress.
David A Andersson, Clive Gentry, Sian Moss, Stuart Bevan. J Neurosci 2008
David A Andersson, Clive Gentry, Sian Moss, Stuart Bevan. J Neurosci 2008
26
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1.
Marcello Trevisani, Jan Siemens, Serena Materazzi, Diana M Bautista, Romina Nassini, Barbara Campi, Noritaka Imamachi, Eunice Andrè, Riccardo Patacchini, Graeme S Cottrell,[...]. Proc Natl Acad Sci U S A 2007
Marcello Trevisani, Jan Siemens, Serena Materazzi, Diana M Bautista, Romina Nassini, Barbara Campi, Noritaka Imamachi, Eunice Andrè, Riccardo Patacchini, Graeme S Cottrell,[...]. Proc Natl Acad Sci U S A 2007
26
Pungent products from garlic activate the sensory ion channel TRPA1.
Diana M Bautista, Pouya Movahed, Andrew Hinman, Helena E Axelsson, Olov Sterner, Edward D Högestätt, David Julius, Sven-Eric Jordt, Peter M Zygmunt. Proc Natl Acad Sci U S A 2005
Diana M Bautista, Pouya Movahed, Andrew Hinman, Helena E Axelsson, Olov Sterner, Edward D Högestätt, David Julius, Sven-Eric Jordt, Peter M Zygmunt. Proc Natl Acad Sci U S A 2005
25
TRPA1 mediates formalin-induced pain.
Colleen R McNamara, Josh Mandel-Brehm, Diana M Bautista, Jan Siemens, Kari L Deranian, Michael Zhao, Neil J Hayward, Jayhong A Chong, David Julius, Magdalene M Moran,[...]. Proc Natl Acad Sci U S A 2007
Colleen R McNamara, Josh Mandel-Brehm, Diana M Bautista, Jan Siemens, Kari L Deranian, Michael Zhao, Neil J Hayward, Jayhong A Chong, David Julius, Magdalene M Moran,[...]. Proc Natl Acad Sci U S A 2007
24
Mammalian Transient Receptor Potential TRPA1 Channels: From Structure to Disease.
Karel Talavera, Justyna B Startek, Julio Alvarez-Collazo, Brett Boonen, Yeranddy A Alpizar, Alicia Sanchez, Robbe Naert, Bernd Nilius. Physiol Rev 2020
Karel Talavera, Justyna B Startek, Julio Alvarez-Collazo, Brett Boonen, Yeranddy A Alpizar, Alicia Sanchez, Robbe Naert, Bernd Nilius. Physiol Rev 2020
25
The capsaicin receptor: a heat-activated ion channel in the pain pathway.
M J Caterina, M A Schumacher, M Tominaga, T A Rosen, J D Levine, D Julius. Nature 1997
M J Caterina, M A Schumacher, M Tominaga, T A Rosen, J D Levine, D Julius. Nature 1997
22
Bimodal action of menthol on the transient receptor potential channel TRPA1.
Yuji Karashima, Nils Damann, Jean Prenen, Karel Talavera, Andrei Segal, Thomas Voets, Bernd Nilius. J Neurosci 2007
Yuji Karashima, Nils Damann, Jean Prenen, Karel Talavera, Andrei Segal, Thomas Voets, Bernd Nilius. J Neurosci 2007
21
TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction.
Kelvin Y Kwan, Andrew J Allchorne, Melissa A Vollrath, Adam P Christensen, Duan-Sun Zhang, Clifford J Woolf, David P Corey. Neuron 2006
Kelvin Y Kwan, Andrew J Allchorne, Melissa A Vollrath, Adam P Christensen, Duan-Sun Zhang, Clifford J Woolf, David P Corey. Neuron 2006
17
Oregano, thyme and clove-derived flavors and skin sensitizers activate specific TRP channels.
Haoxing Xu, Markus Delling, Janice C Jun, David E Clapham. Nat Neurosci 2006
Haoxing Xu, Markus Delling, Janice C Jun, David E Clapham. Nat Neurosci 2006
17
Transient receptor potential ankyrin 1 channel localized to non-neuronal airway cells promotes non-neurogenic inflammation.
Romina Nassini, Pamela Pedretti, Nadia Moretto, Camilla Fusi, Chiara Carnini, Fabrizio Facchinetti, Arturo Roberto Viscomi, Anna Rita Pisano, Susan Stokesberry, Charlott Brunmark,[...]. PLoS One 2012
Romina Nassini, Pamela Pedretti, Nadia Moretto, Camilla Fusi, Chiara Carnini, Fabrizio Facchinetti, Arturo Roberto Viscomi, Anna Rita Pisano, Susan Stokesberry, Charlott Brunmark,[...]. PLoS One 2012
16
Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel.
Yang Suo, Zilong Wang, Lejla Zubcevic, Allen L Hsu, Qianru He, Mario J Borgnia, Ru-Rong Ji, Seok-Yong Lee. Neuron 2020
Yang Suo, Zilong Wang, Lejla Zubcevic, Allen L Hsu, Qianru He, Mario J Borgnia, Ru-Rong Ji, Seok-Yong Lee. Neuron 2020
41
The exceptionally high reactivity of Cys 621 is critical for electrophilic activation of the sensory nerve ion channel TRPA1.
Parmvir K Bahia, Thomas A Parks, Katherine R Stanford, David A Mitchell, Sameer Varma, Stanley M Stevens, Thomas E Taylor-Clark. J Gen Physiol 2016
Parmvir K Bahia, Thomas A Parks, Katherine R Stanford, David A Mitchell, Sameer Varma, Stanley M Stevens, Thomas E Taylor-Clark. J Gen Physiol 2016
50
Molecular characterization of TRPA1 channel activation by cysteine-reactive inflammatory mediators.
Nobuaki Takahashi, Yusuke Mizuno, Daisuke Kozai, Shinichiro Yamamoto, Shigeki Kiyonaka, Takahiro Shibata, Koji Uchida, Yasuo Mori. Channels (Austin) 2008
Nobuaki Takahashi, Yusuke Mizuno, Daisuke Kozai, Shinichiro Yamamoto, Shigeki Kiyonaka, Takahiro Shibata, Koji Uchida, Yasuo Mori. Channels (Austin) 2008
15
The pungency of garlic: activation of TRPA1 and TRPV1 in response to allicin.
Lindsey J Macpherson, Bernhard H Geierstanger, Veena Viswanath, Michael Bandell, Samer R Eid, SunWook Hwang, Ardem Patapoutian. Curr Biol 2005
Lindsey J Macpherson, Bernhard H Geierstanger, Veena Viswanath, Michael Bandell, Samer R Eid, SunWook Hwang, Ardem Patapoutian. Curr Biol 2005
14
The nociceptor ion channel TRPA1 is potentiated and inactivated by permeating calcium ions.
Yuanyuan Y Wang, Rui B Chang, Hang N Waters, David D McKemy, Emily R Liman. J Biol Chem 2008
Yuanyuan Y Wang, Rui B Chang, Hang N Waters, David D McKemy, Emily R Liman. J Biol Chem 2008
14
Activation of transient receptor potential ankyrin 1 by hydrogen peroxide.
Yosuke Sawada, Hiroshi Hosokawa, Kiyoshi Matsumura, Shigeo Kobayashi. Eur J Neurosci 2008
Yosuke Sawada, Hiroshi Hosokawa, Kiyoshi Matsumura, Shigeo Kobayashi. Eur J Neurosci 2008
14
Structure of the TRPV1 ion channel determined by electron cryo-microscopy.
Maofu Liao, Erhu Cao, David Julius, Yifan Cheng. Nature 2013
Maofu Liao, Erhu Cao, David Julius, Yifan Cheng. Nature 2013
14
Cigarette smoke-induced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents.
Eunice Andrè, Barbara Campi, Serena Materazzi, Marcello Trevisani, Silvia Amadesi, Daniela Massi, Christophe Creminon, Natalya Vaksman, Romina Nassini, Maurizio Civelli,[...]. J Clin Invest 2008
Eunice Andrè, Barbara Campi, Serena Materazzi, Marcello Trevisani, Silvia Amadesi, Daniela Massi, Christophe Creminon, Natalya Vaksman, Romina Nassini, Maurizio Civelli,[...]. J Clin Invest 2008
14
TRPV1 structures in distinct conformations reveal activation mechanisms.
Erhu Cao, Maofu Liao, Yifan Cheng, David Julius. Nature 2013
Erhu Cao, Maofu Liao, Yifan Cheng, David Julius. Nature 2013
13
TRPA1 underlies a sensing mechanism for O2.
Nobuaki Takahashi, Tomoyuki Kuwaki, Shigeki Kiyonaka, Tomohiro Numata, Daisuke Kozai, Yusuke Mizuno, Shinichiro Yamamoto, Shinji Naito, Ellen Knevels, Peter Carmeliet,[...]. Nat Chem Biol 2011
Nobuaki Takahashi, Tomoyuki Kuwaki, Shigeki Kiyonaka, Tomohiro Numata, Daisuke Kozai, Yusuke Mizuno, Shinichiro Yamamoto, Shinji Naito, Ellen Knevels, Peter Carmeliet,[...]. Nat Chem Biol 2011
13
TRPA1 channels: molecular sentinels of cellular stress and tissue damage.
Félix Viana. J Physiol 2016
Félix Viana. J Physiol 2016
13
Identification of transmembrane domain 5 as a critical molecular determinant of menthol sensitivity in mammalian TRPA1 channels.
Bailong Xiao, Adrienne E Dubin, Badry Bursulaya, Veena Viswanath, Timothy J Jegla, Ardem Patapoutian. J Neurosci 2008
Bailong Xiao, Adrienne E Dubin, Badry Bursulaya, Veena Viswanath, Timothy J Jegla, Ardem Patapoutian. J Neurosci 2008
13
An ankyrin-like protein with transmembrane domains is specifically lost after oncogenic transformation of human fibroblasts.
D Jaquemar, T Schenker, B Trueb. J Biol Chem 1999
D Jaquemar, T Schenker, B Trueb. J Biol Chem 1999
13
A gain-of-function mutation in TRPA1 causes familial episodic pain syndrome.
Barbara Kremeyer, Francisco Lopera, James J Cox, Aliakmal Momin, Francois Rugiero, Steve Marsh, C Geoffrey Woods, Nicholas G Jones, Kathryn J Paterson, Florence R Fricker,[...]. Neuron 2010
Barbara Kremeyer, Francisco Lopera, James J Cox, Aliakmal Momin, Francois Rugiero, Steve Marsh, C Geoffrey Woods, Nicholas G Jones, Kathryn J Paterson, Florence R Fricker,[...]. Neuron 2010
12
Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing.
Keiichi Nagata, Anne Duggan, Gagan Kumar, Jaime García-Añoveros. J Neurosci 2005
Keiichi Nagata, Anne Duggan, Gagan Kumar, Jaime García-Añoveros. J Neurosci 2005
12
Nicotine activates the chemosensory cation channel TRPA1.
Karel Talavera, Maarten Gees, Yuji Karashima, Víctor M Meseguer, Jeroen A J Vanoirbeek, Nils Damann, Wouter Everaerts, Melissa Benoit, Annelies Janssens, Rudi Vennekens,[...]. Nat Neurosci 2009
Karel Talavera, Maarten Gees, Yuji Karashima, Víctor M Meseguer, Jeroen A J Vanoirbeek, Nils Damann, Wouter Everaerts, Melissa Benoit, Annelies Janssens, Rudi Vennekens,[...]. Nat Neurosci 2009
11
The transient receptor potential channel TRPA1: from gene to pathophysiology.
Bernd Nilius, Giovanni Appendino, Grzegorz Owsianik. Pflugers Arch 2012
Bernd Nilius, Giovanni Appendino, Grzegorz Owsianik. Pflugers Arch 2012
11
Nitrooleic acid, an endogenous product of nitrative stress, activates nociceptive sensory nerves via the direct activation of TRPA1.
Thomas E Taylor-Clark, Srinivas Ghatta, Weston Bettner, Bradley J Undem. Mol Pharmacol 2009
Thomas E Taylor-Clark, Srinivas Ghatta, Weston Bettner, Bradley J Undem. Mol Pharmacol 2009
11
Direct activation of the ion channel TRPA1 by Ca2+.
Sandra Zurborg, Brian Yurgionas, Julia A Jira, Ombretta Caspani, Paul A Heppenstall. Nat Neurosci 2007
Sandra Zurborg, Brian Yurgionas, Julia A Jira, Ombretta Caspani, Paul A Heppenstall. Nat Neurosci 2007
11
Transient receptor potential channels as drug targets: from the science of basic research to the art of medicine.
Bernd Nilius, Arpad Szallasi. Pharmacol Rev 2014
Bernd Nilius, Arpad Szallasi. Pharmacol Rev 2014
11
TRPA1 as a drug target--promise and challenges.
Jun Chen, David H Hackos. Naunyn Schmiedebergs Arch Pharmacol 2015
Jun Chen, David H Hackos. Naunyn Schmiedebergs Arch Pharmacol 2015
11
Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation.
Jun Chen, Shailen K Joshi, Stanley DiDomenico, Richard J Perner, Joe P Mikusa, Donna M Gauvin, Jason A Segreti, Ping Han, Xu-Feng Zhang, Wende Niforatos,[...]. Pain 2011
Jun Chen, Shailen K Joshi, Stanley DiDomenico, Richard J Perner, Joe P Mikusa, Donna M Gauvin, Jason A Segreti, Ping Han, Xu-Feng Zhang, Wende Niforatos,[...]. Pain 2011
11
Non-neuronal expression of transient receptor potential type A1 (TRPA1) in human skin.
Ruzanna Atoyan, Doug Shander, Natalia V Botchkareva. J Invest Dermatol 2009
Ruzanna Atoyan, Doug Shander, Natalia V Botchkareva. J Invest Dermatol 2009
11
TRPA1 channels mediate acute neurogenic inflammation and pain produced by bacterial endotoxins.
Victor Meseguer, Yeranddy A Alpizar, Enoch Luis, Sendoa Tajada, Bristol Denlinger, Otto Fajardo, Jan-Albert Manenschijn, Carlos Fernández-Peña, Arturo Talavera, Tatiana Kichko,[...]. Nat Commun 2014
Victor Meseguer, Yeranddy A Alpizar, Enoch Luis, Sendoa Tajada, Bristol Denlinger, Otto Fajardo, Jan-Albert Manenschijn, Carlos Fernández-Peña, Arturo Talavera, Tatiana Kichko,[...]. Nat Commun 2014
11
Analysis of Drosophila TRPA1 reveals an ancient origin for human chemical nociception.
Kyeongjin Kang, Stefan R Pulver, Vincent C Panzano, Elaine C Chang, Leslie C Griffith, Douglas L Theobald, Paul A Garrity. Nature 2010
Kyeongjin Kang, Stefan R Pulver, Vincent C Panzano, Elaine C Chang, Leslie C Griffith, Douglas L Theobald, Paul A Garrity. Nature 2010
10
A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma.
Ana I Caceres, Marian Brackmann, Maxwell D Elia, Bret F Bessac, Donato del Camino, Marc D'Amours, JoAnn S Witek, Chistopher M Fanger, Jayhong A Chong, Neil J Hayward,[...]. Proc Natl Acad Sci U S A 2009
Ana I Caceres, Marian Brackmann, Maxwell D Elia, Bret F Bessac, Donato del Camino, Marc D'Amours, JoAnn S Witek, Chistopher M Fanger, Jayhong A Chong, Neil J Hayward,[...]. Proc Natl Acad Sci U S A 2009
10
TRPA1: A gatekeeper for inflammation.
Diana M Bautista, Maurizio Pellegrino, Makoto Tsunozaki. Annu Rev Physiol 2013
Diana M Bautista, Maurizio Pellegrino, Makoto Tsunozaki. Annu Rev Physiol 2013
10
Species differences and molecular determinant of TRPA1 cold sensitivity.
Jun Chen, Dawon Kang, Jing Xu, Marc Lake, James O Hogan, Chaohong Sun, Karl Walter, Betty Yao, Donghee Kim. Nat Commun 2013
Jun Chen, Dawon Kang, Jing Xu, Marc Lake, James O Hogan, Chaohong Sun, Karl Walter, Betty Yao, Donghee Kim. Nat Commun 2013
10
The TRPA1 channel in inflammatory and neuropathic pain and migraine.
Romina Nassini, Serena Materazzi, Silvia Benemei, Pierangelo Geppetti. Rev Physiol Biochem Pharmacol 2014
Romina Nassini, Serena Materazzi, Silvia Benemei, Pierangelo Geppetti. Rev Physiol Biochem Pharmacol 2014
10
Endothelium-dependent cerebral artery dilation mediated by TRPA1 and Ca2+-Activated K+ channels.
Scott Earley, Albert L Gonzales, Rachael Crnich. Circ Res 2009
Scott Earley, Albert L Gonzales, Rachael Crnich. Circ Res 2009
10
A TRP channel trio mediates acute noxious heat sensing.
Ine Vandewauw, Katrien De Clercq, Marie Mulier, Katharina Held, Silvia Pinto, Nele Van Ranst, Andrei Segal, Thierry Voet, Rudi Vennekens, Katharina Zimmermann,[...]. Nature 2018
Ine Vandewauw, Katrien De Clercq, Marie Mulier, Katharina Held, Silvia Pinto, Nele Van Ranst, Andrei Segal, Thierry Voet, Rudi Vennekens, Katharina Zimmermann,[...]. Nature 2018
10
Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli.
Julio F Cordero-Morales, Elena O Gracheva, David Julius. Proc Natl Acad Sci U S A 2011
Julio F Cordero-Morales, Elena O Gracheva, David Julius. Proc Natl Acad Sci U S A 2011
10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.