Hirohide Sawada, Hiroshi Ishiguro, Kazuhiro Nishii, Kouji Yamada, Kunihiro Tsuchida, Hisahide Takahashi, Jun Goto, Ichiro Kanazawa, Toshiharu Nagatsu. Neurosci Res 2007
Times Cited: 12
Times Cited: 12
Times Cited
Times Co-cited
Similarity
50
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004
50
Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity.
H Li, S H Li, H Johnston, P F Shelbourne, X J Li. Nat Genet 2000
H Li, S H Li, H Johnston, P F Shelbourne, X J Li. Nat Genet 2000
50
Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration.
Patrick Weydt, Victor V Pineda, Anne E Torrence, Randell T Libby, Terrence F Satterfield, Eduardo R Lazarowski, Merle L Gilbert, Gregory J Morton, Theodor K Bammler, Andrew D Strand,[...]. Cell Metab 2006
Patrick Weydt, Victor V Pineda, Anne E Torrence, Randell T Libby, Terrence F Satterfield, Eduardo R Lazarowski, Merle L Gilbert, Gregory J Morton, Theodor K Bammler, Andrew D Strand,[...]. Cell Metab 2006
50
Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease.
Anthone W Dunah, Hyunkyung Jeong, April Griffin, Yong-Man Kim, David G Standaert, Steven M Hersch, M Maral Mouradian, Anne B Young, Naoko Tanese, Dimitri Krainc. Science 2002
Anthone W Dunah, Hyunkyung Jeong, April Griffin, Yong-Man Kim, David G Standaert, Steven M Hersch, M Maral Mouradian, Anne B Young, Naoko Tanese, Dimitri Krainc. Science 2002
41
Huntingtin aggregate-associated axonal degeneration is an early pathological event in Huntington's disease mice.
H Li, S H Li, Z X Yu, P Shelbourne, X J Li. J Neurosci 2001
H Li, S H Li, Z X Yu, P Shelbourne, X J Li. J Neurosci 2001
41
In vitro analysis of huntingtin-mediated transcriptional repression reveals multiple transcription factor targets.
Weiguo Zhai, Hyunkyung Jeong, Libin Cui, Dimitri Krainc, Robert Tjian. Cell 2005
Weiguo Zhai, Hyunkyung Jeong, Libin Cui, Dimitri Krainc, Robert Tjian. Cell 2005
41
The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.
J S Steffan, A Kazantsev, O Spasic-Boskovic, M Greenwald, Y Z Zhu, H Gohler, E E Wanker, G P Bates, D E Housman, L M Thompson. Proc Natl Acad Sci U S A 2000
J S Steffan, A Kazantsev, O Spasic-Boskovic, M Greenwald, Y Z Zhu, H Gohler, E E Wanker, G P Bates, D E Housman, L M Thompson. Proc Natl Acad Sci U S A 2000
41
Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease.
Melinda M Zeron, Oskar Hansson, Nansheng Chen, Cheryl L Wellington, Blair R Leavitt, Patrik Brundin, Michael R Hayden, Lynn A Raymond. Neuron 2002
Melinda M Zeron, Oskar Hansson, Nansheng Chen, Cheryl L Wellington, Blair R Leavitt, Patrik Brundin, Michael R Hayden, Lynn A Raymond. Neuron 2002
41
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules.
Laurent R Gauthier, Bénédicte C Charrin, Maria Borrell-Pagès, Jim P Dompierre, Hélène Rangone, Fabrice P Cordelières, Jan De Mey, Marcy E MacDonald, Volkmar Lessmann, Sandrine Humbert,[...]. Cell 2004
Laurent R Gauthier, Bénédicte C Charrin, Maria Borrell-Pagès, Jim P Dompierre, Hélène Rangone, Fabrice P Cordelières, Jan De Mey, Marcy E MacDonald, Volkmar Lessmann, Sandrine Humbert,[...]. Cell 2004
41
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
41
Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.
Libin Cui, Hyunkyung Jeong, Fran Borovecki, Christopher N Parkhurst, Naoko Tanese, Dimitri Krainc. Cell 2006
Libin Cui, Hyunkyung Jeong, Fran Borovecki, Christopher N Parkhurst, Naoko Tanese, Dimitri Krainc. Cell 2006
41
p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease.
Byoung-Il Bae, Hong Xu, Shuichi Igarashi, Masahiro Fujimuro, Nishant Agrawal, Yoichi Taya, S Diane Hayward, Timothy H Moran, Craig Montell, Christopher A Ross,[...]. Neuron 2005
Byoung-Il Bae, Hong Xu, Shuichi Igarashi, Masahiro Fujimuro, Nishant Agrawal, Yoichi Taya, S Diane Hayward, Timothy H Moran, Craig Montell, Christopher A Ross,[...]. Neuron 2005
41
Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease.
C Zuccato, A Ciammola, D Rigamonti, B R Leavitt, D Goffredo, L Conti, M E MacDonald, R M Friedlander, V Silani, M R Hayden,[...]. Science 2001
C Zuccato, A Ciammola, D Rigamonti, B R Leavitt, D Goffredo, L Conti, M E MacDonald, R M Friedlander, V Silani, M R Hayden,[...]. Science 2001
33
Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity.
N R Jana, M Tanaka, G h Wang, N Nukina. Hum Mol Genet 2000
N R Jana, M Tanaka, G h Wang, N Nukina. Hum Mol Genet 2000
33
Alterations in N-methyl-D-aspartate receptor sensitivity and magnesium blockade occur early in development in the R6/2 mouse model of Huntington's disease.
Amaal J Starling, Véronique M André, Carlos Cepeda, Marianne de Lima, Scott H Chandler, Michael S Levine. J Neurosci Res 2005
Amaal J Starling, Véronique M André, Carlos Cepeda, Marianne de Lima, Scott H Chandler, Michael S Levine. J Neurosci Res 2005
33
Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates.
D Martindale, A Hackam, A Wieczorek, L Ellerby, C Wellington, K McCutcheon, R Singaraja, P Kazemi-Esfarjani, R Devon, S U Kim,[...]. Nat Genet 1998
D Martindale, A Hackam, A Wieczorek, L Ellerby, C Wellington, K McCutcheon, R Singaraja, P Kazemi-Esfarjani, R Devon, S U Kim,[...]. Nat Genet 1998
33
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes.
Chiara Zuccato, Marzia Tartari, Andrea Crotti, Donato Goffredo, Marta Valenza, Luciano Conti, Tiziana Cataudella, Blair R Leavitt, Michael R Hayden, Tõnis Timmusk,[...]. Nat Genet 2003
Chiara Zuccato, Marzia Tartari, Andrea Crotti, Donato Goffredo, Marta Valenza, Luciano Conti, Tiziana Cataudella, Blair R Leavitt, Michael R Hayden, Tõnis Timmusk,[...]. Nat Genet 2003
33
Haloperidol protects striatal neurons from dysfunction induced by mutated huntingtin in vivo.
Delphine Charvin, Emmanuel Roze, Valérie Perrin, Carole Deyts, Sandrine Betuing, Christiane Pagès, Etienne Régulier, Ruth Luthi-Carter, Emmanuel Brouillet, Nicole Déglon,[...]. Neurobiol Dis 2008
Delphine Charvin, Emmanuel Roze, Valérie Perrin, Carole Deyts, Sandrine Betuing, Christiane Pagès, Etienne Régulier, Ruth Luthi-Carter, Emmanuel Brouillet, Nicole Déglon,[...]. Neurobiol Dis 2008
33
Amyloid formation by mutant huntingtin: threshold, progressivity and recruitment of normal polyglutamine proteins.
C C Huang, P W Faber, F Persichetti, V Mittal, J P Vonsattel, M E MacDonald, J F Gusella. Somat Cell Mol Genet 1998
C C Huang, P W Faber, F Persichetti, V Mittal, J P Vonsattel, M E MacDonald, J F Gusella. Somat Cell Mol Genet 1998
33
Transcriptional abnormalities in Huntington disease.
Katharine L Sugars, David C Rubinsztein. Trends Genet 2003
Katharine L Sugars, David C Rubinsztein. Trends Genet 2003
33
Neuroprotective effects of synaptic modulation in Huntington's disease R6/2 mice.
Edward C Stack, Alpaslan Dedeoglu, Karen M Smith, Kerry Cormier, James K Kubilus, Mikhail Bogdanov, Wayne R Matson, Lichuan Yang, Bruce G Jenkins, Ruth Luthi-Carter,[...]. J Neurosci 2007
Edward C Stack, Alpaslan Dedeoglu, Karen M Smith, Kerry Cormier, James K Kubilus, Mikhail Bogdanov, Wayne R Matson, Lichuan Yang, Bruce G Jenkins, Ruth Luthi-Carter,[...]. J Neurosci 2007
33
Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription.
T Shimohata, T Nakajima, M Yamada, C Uchida, O Onodera, S Naruse, T Kimura, R Koide, K Nozaki, Y Sano,[...]. Nat Genet 2000
T Shimohata, T Nakajima, M Yamada, C Uchida, O Onodera, S Naruse, T Kimura, R Koide, K Nozaki, Y Sano,[...]. Nat Genet 2000
33
Interaction of Huntington disease protein with transcriptional activator Sp1.
Shi-Hua Li, Anna L Cheng, Hui Zhou, Suzanne Lam, Manjula Rao, He Li, Xiao-Jiang Li. Mol Cell Biol 2002
Shi-Hua Li, Anna L Cheng, Hui Zhou, Suzanne Lam, Manjula Rao, He Li, Xiao-Jiang Li. Mol Cell Biol 2002
33
Widespread disruption of repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy at its target genes in Huntington's disease.
Chiara Zuccato, Nikolai Belyaev, Paola Conforti, Lezanne Ooi, Marzia Tartari, Evangelia Papadimou, Marcy MacDonald, Elisa Fossale, Scott Zeitlin, Noel Buckley,[...]. J Neurosci 2007
Chiara Zuccato, Nikolai Belyaev, Paola Conforti, Lezanne Ooi, Marzia Tartari, Evangelia Papadimou, Marcy MacDonald, Elisa Fossale, Scott Zeitlin, Noel Buckley,[...]. J Neurosci 2007
33
Identities of sequestered proteins in aggregates from cells with induced polyglutamine expression.
S T Suhr, M C Senut, J P Whitelegge, K F Faull, D B Cuizon, F H Gage. J Cell Biol 2001
S T Suhr, M C Senut, J P Whitelegge, K F Faull, D B Cuizon, F H Gage. J Cell Biol 2001
33
Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity.
F C Nucifora , M Sasaki, M F Peters, H Huang, J K Cooper, M Yamada, H Takahashi, S Tsuji, J Troncoso, V L Dawson,[...]. Science 2001
F C Nucifora , M Sasaki, M F Peters, H Huang, J K Cooper, M Yamada, H Takahashi, S Tsuji, J Troncoso, V L Dawson,[...]. Science 2001
33
Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene.
J H Cha, C M Kosinski, J A Kerner, S A Alsdorf, L Mangiarini, S W Davies, J B Penney, G P Bates, A B Young. Proc Natl Acad Sci U S A 1998
J H Cha, C M Kosinski, J A Kerner, S A Alsdorf, L Mangiarini, S W Davies, J B Penney, G P Bates, A B Young. Proc Natl Acad Sci U S A 1998
33
Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.
F Saudou, S Finkbeiner, D Devys, M E Greenberg. Cell 1998
F Saudou, S Finkbeiner, D Devys, M E Greenberg. Cell 1998
33
Global changes to the ubiquitin system in Huntington's disease.
Eric J Bennett, Thomas A Shaler, Ben Woodman, Kwon-Yul Ryu, Tatiana S Zaitseva, Christopher H Becker, Gillian P Bates, Howard Schulman, Ron R Kopito. Nature 2007
Eric J Bennett, Thomas A Shaler, Ben Woodman, Kwon-Yul Ryu, Tatiana S Zaitseva, Christopher H Becker, Gillian P Bates, Howard Schulman, Ron R Kopito. Nature 2007
33
Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain.
Ruth Luthi-Carter, Sarah A Hanson, Andrew D Strand, Donald A Bergstrom, Wanjoo Chun, Nikki L Peters, Annette M Woods, Edmond Y Chan, Charles Kooperberg, Dimitri Krainc,[...]. Hum Mol Genet 2002
Ruth Luthi-Carter, Sarah A Hanson, Andrew D Strand, Donald A Bergstrom, Wanjoo Chun, Nikki L Peters, Annette M Woods, Edmond Y Chan, Charles Kooperberg, Dimitri Krainc,[...]. Hum Mol Genet 2002
33
Dopaminergic signaling and striatal neurodegeneration in Huntington's disease.
Tie-Shan Tang, Xi Chen, Jing Liu, Ilya Bezprozvanny. J Neurosci 2007
Tie-Shan Tang, Xi Chen, Jing Liu, Ilya Bezprozvanny. J Neurosci 2007
33
Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins.
Prasanna Venkatraman, Ronald Wetzel, Motomasa Tanaka, Nobuyuki Nukina, Alfred L Goldberg. Mol Cell 2004
Prasanna Venkatraman, Ronald Wetzel, Motomasa Tanaka, Nobuyuki Nukina, Alfred L Goldberg. Mol Cell 2004
33
Absence of behavioral abnormalities and neurodegeneration in vivo despite widespread neuronal huntingtin inclusions.
Elizabeth J Slow, Rona K Graham, Alexander P Osmand, Rebecca S Devon, Ge Lu, Yu Deng, Jacqui Pearson, Kuljeet Vaid, Nagat Bissada, Ronald Wetzel,[...]. Proc Natl Acad Sci U S A 2005
Elizabeth J Slow, Rona K Graham, Alexander P Osmand, Rebecca S Devon, Ge Lu, Yu Deng, Jacqui Pearson, Kuljeet Vaid, Nagat Bissada, Ronald Wetzel,[...]. Proc Natl Acad Sci U S A 2005
33
Decreased expression of striatal signaling genes in a mouse model of Huntington's disease.
R Luthi-Carter, A Strand, N L Peters, S M Solano, Z R Hollingsworth, A S Menon, A S Frey, B S Spektor, E B Penney, G Schilling,[...]. Hum Mol Genet 2000
R Luthi-Carter, A Strand, N L Peters, S M Solano, Z R Hollingsworth, A S Menon, A S Frey, B S Spektor, E B Penney, G Schilling,[...]. Hum Mol Genet 2000
33
Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo.
E Scherzinger, R Lurz, M Turmaine, L Mangiarini, B Hollenbach, R Hasenbank, G P Bates, S W Davies, H Lehrach, E E Wanker. Cell 1997
E Scherzinger, R Lurz, M Turmaine, L Mangiarini, B Hollenbach, R Hasenbank, G P Bates, S W Davies, H Lehrach, E E Wanker. Cell 1997
33
Brain-derived neurotrophic factor restores synaptic plasticity in a knock-in mouse model of Huntington's disease.
Gary Lynch, Eniko A Kramar, Christopher S Rex, Yousheng Jia, Danielle Chappas, Christine M Gall, Danielle A Simmons. J Neurosci 2007
Gary Lynch, Eniko A Kramar, Christopher S Rex, Yousheng Jia, Danielle Chappas, Christine M Gall, Danielle A Simmons. J Neurosci 2007
33
Altered NMDA receptor trafficking in a yeast artificial chromosome transgenic mouse model of Huntington's disease.
Mannie M Y Fan, Herman B Fernandes, Lily Y J Zhang, Michael R Hayden, Lynn A Raymond. J Neurosci 2007
Mannie M Y Fan, Herman B Fernandes, Lily Y J Zhang, Michael R Hayden, Lynn A Raymond. J Neurosci 2007
33
Mitogen- and stress-activated protein kinase-1 deficiency is involved in expanded-huntingtin-induced transcriptional dysregulation and striatal death.
Emmanuel Roze, Sandrine Betuing, Carole Deyts, Estelle Marcon, Karen Brami-Cherrier, Christiane Pagès, Sandrine Humbert, Karine Mérienne, Jocelyne Caboche. FASEB J 2008
Emmanuel Roze, Sandrine Betuing, Carole Deyts, Estelle Marcon, Karen Brami-Cherrier, Christiane Pagès, Sandrine Humbert, Karine Mérienne, Jocelyne Caboche. FASEB J 2008
33
Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.
Alexander V Panov, Claire-Anne Gutekunst, Blair R Leavitt, Michael R Hayden, James R Burke, Warren J Strittmatter, J Timothy Greenamyre. Nat Neurosci 2002
Alexander V Panov, Claire-Anne Gutekunst, Blair R Leavitt, Michael R Hayden, James R Burke, Warren J Strittmatter, J Timothy Greenamyre. Nat Neurosci 2002
33
Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro.
Eugenia Trushina, Roy B Dyer, John D Badger, Daren Ure, Lars Eide, David D Tran, Brent T Vrieze, Valerie Legendre-Guillemin, Peter S McPherson, Bhaskar S Mandavilli,[...]. Mol Cell Biol 2004
Eugenia Trushina, Roy B Dyer, John D Badger, Daren Ure, Lars Eide, David D Tran, Brent T Vrieze, Valerie Legendre-Guillemin, Peter S McPherson, Bhaskar S Mandavilli,[...]. Mol Cell Biol 2004
33
Age-dependent and tissue-specific CAG repeat instability occurs in mouse knock-in for a mutant Huntington's disease gene.
H Ishiguro, K Yamada, H Sawada, K Nishii, N Ichino, M Sawada, Y Kurosawa, N Matsushita, K Kobayashi, J Goto,[...]. J Neurosci Res 2001
H Ishiguro, K Yamada, H Sawada, K Nishii, N Ichino, M Sawada, Y Kurosawa, N Matsushita, K Kobayashi, J Goto,[...]. J Neurosci Res 2001
33
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
33
Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects.
Ruth Luthi-Carter, Andrew D Strand, Sarah A Hanson, Charles Kooperberg, Gabriele Schilling, Albert R La Spada, Diane E Merry, Anne B Young, Christopher A Ross, David R Borchelt,[...]. Hum Mol Genet 2002
Ruth Luthi-Carter, Andrew D Strand, Sarah A Hanson, Charles Kooperberg, Gabriele Schilling, Albert R La Spada, Diane E Merry, Anne B Young, Christopher A Ross, David R Borchelt,[...]. Hum Mol Genet 2002
33
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
33
Time-lapse analysis of aggregate formation in an inducible PC12 cell model of Huntington's disease reveals time-dependent aggregate formation that transiently delays cell death.
B Gong, M C Y Lim, J Wanderer, A Wyttenbach, A J Morton. Brain Res Bull 2008
B Gong, M C Y Lim, J Wanderer, A Wyttenbach, A J Morton. Brain Res Bull 2008
25
Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila.
Shermali Gunawardena, Lu-Shiun Her, Richard G Brusch, Robert A Laymon, Ingrid R Niesman, Beth Gordesky-Gold, Louis Sintasath, Nancy M Bonini, Lawrence S B Goldstein. Neuron 2003
Shermali Gunawardena, Lu-Shiun Her, Richard G Brusch, Robert A Laymon, Ingrid R Niesman, Beth Gordesky-Gold, Louis Sintasath, Nancy M Bonini, Lawrence S B Goldstein. Neuron 2003
25
Complex I defect in muscle from patients with Huntington's disease.
J Arenas, Y Campos, R Ribacoba, M A Martín, J C Rubio, P Ablanedo, A Cabello. Ann Neurol 1998
J Arenas, Y Campos, R Ribacoba, M A Martín, J C Rubio, P Ablanedo, A Cabello. Ann Neurol 1998
25
Huntingtin facilitates dynein/dynactin-mediated vesicle transport.
Juliane P Caviston, Jennifer L Ross, Sheila M Antony, Mariko Tokito, Erika L F Holzbaur. Proc Natl Acad Sci U S A 2007
Juliane P Caviston, Jennifer L Ross, Sheila M Antony, Mariko Tokito, Erika L F Holzbaur. Proc Natl Acad Sci U S A 2007
25
Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration.
Andrew D Strand, Zachary C Baquet, Aaron K Aragaki, Peter Holmans, Lichuan Yang, Carine Cleren, M Flint Beal, Lesley Jones, Charles Kooperberg, James M Olson,[...]. J Neurosci 2007
Andrew D Strand, Zachary C Baquet, Aaron K Aragaki, Peter Holmans, Lichuan Yang, Carine Cleren, M Flint Beal, Lesley Jones, Charles Kooperberg, James M Olson,[...]. J Neurosci 2007
25
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.