A citation-based method for searching scientific literature

Takanori Muto, Daisuke Tsuchiya, Kosuke Morikawa, Hisato Jingami. Proc Natl Acad Sci U S A 2007
Times Cited: 265







List of co-cited articles
1548 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor.
N Kunishima, Y Shimada, Y Tsuji, T Sato, M Yamamoto, T Kumasaka, S Nakanishi, H Jingami, K Morikawa. Nature 2000
932
73

Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator.
Huixian Wu, Chong Wang, Karen J Gregory, Gye Won Han, Hyekyung P Cho, Yan Xia, Colleen M Niswender, Vsevolod Katritch, Jens Meiler, Vadim Cherezov,[...]. Science 2014
361
49

Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain.
Andrew S Doré, Krzysztof Okrasa, Jayesh C Patel, Maria Serrano-Vega, Kirstie Bennett, Robert M Cooke, James C Errey, Ali Jazayeri, Samir Khan, Ben Tehan,[...]. Nature 2014
289
41

Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+.
Daisuke Tsuchiya, Naoki Kunishima, Narutoshi Kamiya, Hisato Jingami, Kosuke Morikawa. Proc Natl Acad Sci U S A 2002
279
41

Metabotropic glutamate receptors: physiology, pharmacology, and disease.
Colleen M Niswender, P Jeffrey Conn. Annu Rev Pharmacol Toxicol 2010
33

Structural insights into the activation of metabotropic glutamate receptors.
Antoine Koehl, Hongli Hu, Dan Feng, Bingfa Sun, Yan Zhang, Michael J Robertson, Matthew Chu, Tong Sun Kobilka, Toon Laeremans, Jan Steyaert,[...]. Nature 2019
132
33

Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer.
Li Xue, Xavier Rovira, Pauline Scholler, Han Zhao, Jianfeng Liu, Jean-Philippe Pin, Philippe Rondard. Nat Chem Biol 2015
120
28

Closed state of both binding domains of homodimeric mGlu receptors is required for full activity.
Julie Kniazeff, Anne-Sophie Bessis, Damien Maurel, Hervé Ansanay, Laurent Prézeau, Jean-Philippe Pin. Nat Struct Mol Biol 2004
215
24

A new approach to analyze cell surface protein complexes reveals specific heterodimeric metabotropic glutamate receptors.
Etienne Doumazane, Pauline Scholler, Jurriaan M Zwier, Eric Trinquet, Philippe Rondard, Jean-Philippe Pin. FASEB J 2011
198
24

Distinct roles of metabotropic glutamate receptor dimerization in agonist activation and G-protein coupling.
Driss El Moustaine, Sébastien Granier, Etienne Doumazane, Pauline Scholler, Rita Rahmeh, Patrick Bron, Bernard Mouillac, Jean-Louis Banères, Philippe Rondard, Jean-Philippe Pin. Proc Natl Acad Sci U S A 2012
120
22

Fragment and Structure-Based Drug Discovery for a Class C GPCR: Discovery of the mGlu5 Negative Allosteric Modulator HTL14242 (3-Chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile).
John A Christopher, Sarah J Aves, Kirstie A Bennett, Andrew S Doré, James C Errey, Ali Jazayeri, Fiona H Marshall, Krzysztof Okrasa, Maria J Serrano-Vega, Benjamin G Tehan,[...]. J Med Chem 2015
104
22

Structural mechanism of ligand activation in human GABA(B) receptor.
Yong Geng, Martin Bush, Lidia Mosyak, Feng Wang, Qing R Fan. Nature 2013
114
22

Structural mechanism of ligand activation in human calcium-sensing receptor.
Yong Geng, Lidia Mosyak, Igor Kurinov, Hao Zuo, Emmanuel Sturchler, Tat Cheung Cheng, Prakash Subramanyam, Alice P Brown, Sarah C Brennan, Hee-Chang Mun,[...]. Elife 2016
113
22

Organization and functions of mGlu and GABAB receptor complexes.
Jean-Philippe Pin, Bernhard Bettler. Nature 2016
126
22

Illuminating the activation mechanisms and allosteric properties of metabotropic glutamate receptors.
Etienne Doumazane, Pauline Scholler, Ludovic Fabre, Jurriaan M Zwier, Eric Trinquet, Jean-Philippe Pin, Philippe Rondard. Proc Natl Acad Sci U S A 2013
72
29

Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors.
Jean-Philippe Pin, Thierry Galvez, Laurent Prézeau. Pharmacol Ther 2003
449
21

Human receptors for sweet and umami taste.
Xiaodong Li, Lena Staszewski, Hong Xu, Kyle Durick, Mark Zoller, Elliot Adler. Proc Natl Acad Sci U S A 2002
838
20

Mammalian sweet taste receptors.
G Nelson, M A Hoon, J Chandrashekar, Y Zhang, N J Ryba, C S Zuker. Cell 2001
20

Conformational dynamics of a class C G-protein-coupled receptor.
Reza Vafabakhsh, Joshua Levitz, Ehud Y Isacoff. Nature 2015
99
20

Metabotropic glutamate receptor 5 is a disulfide-linked dimer.
C Romano, W L Yang, K L O'Malley. J Biol Chem 1996
416
17

Dimers and beyond: The functional puzzles of class C GPCRs.
Julie Kniazeff, Laurent Prézeau, Philippe Rondard, Jean-Philippe Pin, Cyril Goudet. Pharmacol Ther 2011
159
17

Selective actions of novel allosteric modulators reveal functional heteromers of metabotropic glutamate receptors in the CNS.
Shen Yin, Meredith J Noetzel, Kari A Johnson, Rocio Zamorano, Nidhi Jalan-Sakrikar, Karen J Gregory, P Jeffrey Conn, Colleen M Niswender. J Neurosci 2014
80
21

Mechanism of Assembly and Cooperativity of Homomeric and Heteromeric Metabotropic Glutamate Receptors.
Joshua Levitz, Chris Habrian, Shashank Bharill, Zhu Fu, Reza Vafabakhsh, Ehud Y Isacoff. Neuron 2016
89
19

Different functional roles of T1R subunits in the heteromeric taste receptors.
Hong Xu, Lena Staszewski, Huixian Tang, Elliot Adler, Mark Zoller, Xiaodong Li. Proc Natl Acad Sci U S A 2004
308
16

Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist.
Chen Zhang, Tuo Zhang, Juan Zou, Cassandra Lynn Miller, Rakshya Gorkhali, Jeong-Yeh Yang, Anthony Schilmiller, Shuo Wang, Kenneth Huang, Edward M Brown,[...]. Sci Adv 2016
71
22

Interdomain movements in metabotropic glutamate receptor activation.
Siluo Huang, Jianhua Cao, Ming Jiang, Gilles Labesse, Jianfeng Liu, Jean-Philippe Pin, Philippe Rondard. Proc Natl Acad Sci U S A 2011
59
25

Structural diversity of G protein-coupled receptors and significance for drug discovery.
Malin C Lagerström, Helgi B Schiöth. Nat Rev Drug Discov 2008
986
14

Heptahelical domain of metabotropic glutamate receptor 5 behaves like rhodopsin-like receptors.
Cyril Goudet, Florence Gaven, Julie Kniazeff, Claire Vol, Jiangfeng Liu, Martin Cohen-Gonsaud, Francine Acher, Laurent Prézeau, Jean Philippe Pin. Proc Natl Acad Sci U S A 2004
157
14

An amino-acid taste receptor.
Greg Nelson, Jayaram Chandrashekar, Mark A Hoon, Luxin Feng, Grace Zhao, Nicholas J P Ryba, Charles S Zuker. Nature 2002
890
14

Asymmetric functioning of dimeric metabotropic glutamate receptors disclosed by positive allosteric modulators.
Cyril Goudet, Julie Kniazeff, Veronika Hlavackova, Fanny Malhaire, Damien Maurel, Francine Acher, Jaroslav Blahos, Laurent Prézeau, Jean-Philippe Pin. J Biol Chem 2005
103
13

Metabotropic glutamate receptors: from the workbench to the bedside.
F Nicoletti, J Bockaert, G L Collingridge, P J Conn, F Ferraguti, D D Schoepp, J T Wroblewski, J P Pin. Neuropharmacology 2011
414
13

The receptors for mammalian sweet and umami taste.
Grace Q Zhao, Yifeng Zhang, Mark A Hoon, Jayaram Chandrashekar, Isolde Erlenbach, Nicholas J P Ryba, Charles S Zuker. Cell 2003
779
13

Pharmacology and functions of metabotropic glutamate receptors.
P J Conn, J P Pin. Annu Rev Pharmacol Toxicol 1997
12


Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells.
David Moreno Delgado, Thor C Møller, Jeanne Ster, Jesús Giraldo, Damien Maurel, Xavier Rovira, Pauline Scholler, Jurriaan M Zwier, Julie Perroy, Thierry Durroux,[...]. Elife 2017
42
28

Structure-Based Optimization Strategies for G Protein-Coupled Receptor (GPCR) Allosteric Modulators: A Case Study from Analyses of New Metabotropic Glutamate Receptor 5 (mGlu5) X-ray Structures.
John A Christopher, Zoltán Orgován, Miles Congreve, Andrew S Doré, James C Errey, Fiona H Marshall, Jonathan S Mason, Krzysztof Okrasa, Prakash Rucktooa, Maria J Serrano-Vega,[...]. J Med Chem 2019
45
26

Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders.
P Jeffrey Conn, Arthur Christopoulos, Craig W Lindsley. Nat Rev Drug Discov 2009
759
11

Pharmacological agents acting at subtypes of metabotropic glutamate receptors.
D D Schoepp, D E Jane, J A Monn. Neuropharmacology 1999
878
11

Crystal structure of the β2 adrenergic receptor-Gs protein complex.
Søren G F Rasmussen, Brian T DeVree, Yaozhong Zou, Andrew C Kruse, Ka Young Chung, Tong Sun Kobilka, Foon Sun Thian, Pil Seok Chae, Els Pardon, Diane Calinski,[...]. Nature 2011
11

Evidence for a single heptahelical domain being turned on upon activation of a dimeric GPCR.
Veronika Hlavackova, Cyril Goudet, Julie Kniazeff, Alice Zikova, Damien Maurel, Claire Vol, Johana Trojanova, Laurent Prézeau, Jean-Philippe Pin, Jaroslav Blahos. EMBO J 2005
119
11

CPCCOEt, a noncompetitive metabotropic glutamate receptor 1 antagonist, inhibits receptor signaling without affecting glutamate binding.
S Litschig, F Gasparini, D Rueegg, N Stoehr, P J Flor, I Vranesic, L Prézeau, J P Pin, C Thomsen, R Kuhn. Mol Pharmacol 1999
282
11

The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints.
Robert Fredriksson, Malin C Lagerström, Lars-Gustav Lundin, Helgi B Schiöth. Mol Pharmacol 2003
11

Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid.
E M Brown, G Gamba, D Riccardi, M Lombardi, R Butters, O Kifor, A Sun, M A Hediger, J Lytton, S C Hebert. Nature 1993
11



Probing the metabotropic glutamate receptor 5 (mGlu₅) positive allosteric modulator (PAM) binding pocket: discovery of point mutations that engender a "molecular switch" in PAM pharmacology.
Karen J Gregory, Elizabeth D Nguyen, Sean D Reiff, Emma F Squire, Shaun R Stauffer, Craig W Lindsley, Jens Meiler, P Jeffrey Conn. Mol Pharmacol 2013
60
16

2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist.
F Gasparini, K Lingenhöhl, N Stoehr, P J Flor, M Heinrich, I Vranesic, M Biollaz, H Allgeier, R Heckendorn, S Urwyler,[...]. Neuropharmacology 1999
644
10

Molecular mechanism of the sweet taste enhancers.
Feng Zhang, Boris Klebansky, Richard M Fine, Haitian Liu, Hong Xu, Guy Servant, Mark Zoller, Catherine Tachdjian, Xiaodong Li. Proc Natl Acad Sci U S A 2010
109
10

The cysteine-rich region of T1R3 determines responses to intensely sweet proteins.
Peihua Jiang, Qingzhou Ji, Zhan Liu, Lenore A Snyder, Lumie M J Benard, Robert F Margolskee, Marianna Max. J Biol Chem 2004
187
10

Molecular mechanism for the umami taste synergism.
Feng Zhang, Boris Klebansky, Richard M Fine, Hong Xu, Alexey Pronin, Haitian Liu, Catherine Tachdjian, Xiaodong Li. Proc Natl Acad Sci U S A 2008
187
10


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.