A citation-based method for searching scientific literature

Andrew M Ellisdon, Mary C Pearce, Stephen P Bottomley. J Mol Biol 2007
Times Cited: 57







List of co-cited articles
618 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


The two-stage pathway of ataxin-3 fibrillogenesis involves a polyglutamine-independent step.
Andrew M Ellisdon, Bronwen Thomas, Stephen P Bottomley. J Biol Chem 2006
135
75

Characterization of the structure and the amyloidogenic properties of the Josephin domain of the polyglutamine-containing protein ataxin-3.
Laura Masino, Giuseppe Nicastro, Rajesh P Menon, Fabrizio Dal Piaz, Lesley Calder, Annalisa Pastore. J Mol Biol 2004
98
63

The solution structure of the Josephin domain of ataxin-3: structural determinants for molecular recognition.
Giuseppe Nicastro, Rajesh P Menon, Laura Masino, Philip P Knowles, Neil Q McDonald, Annalisa Pastore. Proc Natl Acad Sci U S A 2005
138
45

Towards a structural understanding of the fibrillization pathway in Machado-Joseph's disease: trapping early oligomers of non-expanded ataxin-3.
Luís Gales, Luísa Cortes, Carla Almeida, Carlos V Melo, Maria do Carmo Costa, Patrícia Maciel, David T Clarke, Ana Margarida Damas, Sandra Macedo-Ribeiro. J Mol Biol 2005
60
38

Huntington's disease age-of-onset linked to polyglutamine aggregation nucleation.
Songming Chen, Frank A Ferrone, Ronald Wetzel. Proc Natl Acad Sci U S A 2002
393
33

Josephin domain of ataxin-3 contains two distinct ubiquitin-binding sites.
Giuseppe Nicastro, Laura Masino, Veronica Esposito, Rajesh P Menon, Alfonso De Simone, Franca Fraternali, Annalisa Pastore. Biopolymers 2009
64
33

Functional interactions as a survival strategy against abnormal aggregation.
Laura Masino, Giuseppe Nicastro, Lesley Calder, Michele Vendruscolo, Annalisa Pastore. FASEB J 2011
63
33

Polyglutamine expansion in ataxin-3 does not affect protein stability: implications for misfolding and disease.
Michelle K M Chow, Andrew M Ellisdon, Lisa D Cabrita, Stephen P Bottomley. J Biol Chem 2004
57
31

Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism.
Ashwani K Thakur, Murali Jayaraman, Rakesh Mishra, Monika Thakur, Veronique M Chellgren, In-Ja L Byeon, Dalaver H Anjum, Ravindra Kodali, Trevor P Creamer, James F Conway,[...]. Nat Struct Mol Biol 2009
307
31

Flanking domain stability modulates the aggregation kinetics of a polyglutamine disease protein.
Helen M Saunders, Dimitri Gilis, Marianne Rooman, Yves Dehouck, Amy L Robertson, Stephen P Bottomley. Protein Sci 2011
30
60


Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis.
Rakez Kayed, Elizabeth Head, Jennifer L Thompson, Theresa M McIntire, Saskia C Milton, Carl W Cotman, Charles G Glabe. Science 2003
26

CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1.
Y Kawaguchi, T Okamoto, M Taniwaki, M Aizawa, M Inoue, S Katayama, H Kawakami, S Nakamura, M Nishimura, I Akiguchi. Nat Genet 1994
26

Glutamine repeats and neurodegeneration.
H Y Zoghbi, H T Orr. Annu Rev Neurosci 2000
967
24


Multi-domain misfolding: understanding the aggregation pathway of polyglutamine proteins.
Helen M Saunders, Stephen P Bottomley. Protein Eng Des Sel 2009
60
24

Domain architecture of the polyglutamine protein ataxin-3: a globular domain followed by a flexible tail.
Laura Masino, Valeria Musi, Rajesh P Menon, Paola Fusi, Geoff Kelly, Thomas A Frenkiel, Yvon Trottier, Annalisa Pastore. FEBS Lett 2003
91
24

A toxic monomeric conformer of the polyglutamine protein.
Yoshitaka Nagai, Takashi Inui, H Akiko Popiel, Nobuhiro Fujikake, Kazuhiro Hasegawa, Yoshihiro Urade, Yuji Goto, Hironobu Naiki, Tatsushi Toda. Nat Struct Mol Biol 2007
237
22


Flanking sequences profoundly alter polyglutamine toxicity in yeast.
Martin L Duennwald, Smitha Jagadish, Paul J Muchowski, Susan Lindquist. Proc Natl Acad Sci U S A 2006
217
22

Structural and functional analysis of the Josephin domain of the polyglutamine protein ataxin-3.
Michelle K M Chow, Joel P Mackay, James C Whisstock, Martin J Scanlon, Stephen P Bottomley. Biochem Biophys Res Commun 2004
48
27

Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3.
H L Paulson, M K Perez, Y Trottier, J Q Trojanowski, S H Subramony, S S Das, P Vig, J L Mandel, K H Fischbeck, R N Pittman. Neuron 1997
666
22

Small heat-shock proteins interact with a flanking domain to suppress polyglutamine aggregation.
Amy L Robertson, Stephen J Headey, Helen M Saunders, Heath Ecroyd, Martin J Scanlon, John A Carver, Stephen P Bottomley. Proc Natl Acad Sci U S A 2010
69
22

The Josephin domain determines the morphological and mechanical properties of ataxin-3 fibrils.
Laura Masino, Giuseppe Nicastro, Alfonso De Simone, Lesley Calder, Justin Molloy, Annalisa Pastore. Biophys J 2011
39
33

Polyglutamine is not all: the functional role of the AXH domain in the ataxin-1 protein.
Cesira de Chiara, Rajesh P Menon, Fabrizio Dal Piaz, Lesley Calder, Annalisa Pastore. J Mol Biol 2005
62
21


Oligoproline effects on polyglutamine conformation and aggregation.
Anusri Bhattacharyya, Ashwani K Thakur, Veronique M Chellgren, Geetha Thiagarajan, Angela D Williams, Brian W Chellgren, Trevor P Creamer, Ronald Wetzel. J Mol Biol 2006
191
21

The structural impact of a polyglutamine tract is location-dependent.
Amy L Robertson, James Horne, Andrew M Ellisdon, Bronwen Thomas, Martin J Scanlon, Stephen P Bottomley. Biophys J 2008
28
42

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004
19

Protein misfolding, functional amyloid, and human disease.
Fabrizio Chiti, Christopher M Dobson. Annu Rev Biochem 2006
19

Structure validation of the Josephin domain of ataxin-3: conclusive evidence for an open conformation.
Giuseppe Nicastro, Michael Habeck, Laura Masino, Dmitri I Svergun, Annalisa Pastore. J Biomol NMR 2006
34
32

Deubiquitinating function of ataxin-3: insights from the solution structure of the Josephin domain.
Yuxin Mao, Francesca Senic-Matuglia, Pier Paolo Di Fiore, Simona Polo, Michael E Hodsdon, Pietro De Camilli. Proc Natl Acad Sci U S A 2005
121
19

The deubiquitinating enzyme ataxin-3, a polyglutamine disease protein, edits Lys63 linkages in mixed linkage ubiquitin chains.
Brett J Winborn, Sue M Travis, Sokol V Todi, K Matthew Scaglione, Ping Xu, Aislinn J Williams, Robert E Cohen, Junmin Peng, Henry L Paulson. J Biol Chem 2008
188
19


A major role for side-chain polyglutamine hydrogen bonding in irreversible ataxin-3 aggregation.
Antonino Natalello, Anna Maria Frana, Annalisa Relini, Alessandra Apicella, Gaetano Invernizzi, Carlo Casari, Alessandra Gliozzi, Silvia Maria Doglia, Paolo Tortora, Maria Elena Regonesi. PLoS One 2011
53
20

Pathogenic and non-pathogenic polyglutamine tracts have similar structural properties: towards a length-dependent toxicity gradient.
Fabrice A C Klein, Annalisa Pastore, Laura Masino, Gabrielle Zeder-Lutz, Hélène Nierengarten, Mustapha Oulad-Abdelghani, Danièle Altschuh, Jean-Louis Mandel, Yvon Trottier. J Mol Biol 2007
76
17


The interplay between PolyQ and protein context delays aggregation by forming a reservoir of protofibrils.
Donatella Bulone, Laura Masino, David J Thomas, Pier Luigi San Biagio, Annalisa Pastore. PLoS One 2006
51
17

Amyloid-like features of polyglutamine aggregates and their assembly kinetics.
Songming Chen, Valerie Berthelier, J Bradley Hamilton, Brian O'Nuallain, Ronald Wetzel. Biochemistry 2002
257
15

An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis.
Annett Boeddrich, Sébastien Gaumer, Annette Haacke, Nikolay Tzvetkov, Mario Albrecht, Bernd O Evert, Eva C Müller, Rudi Lurz, Peter Breuer, Nancy Schugardt,[...]. EMBO J 2006
122
15

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo.
E Scherzinger, R Lurz, M Turmaine, L Mangiarini, B Hollenbach, R Hasenbank, G P Bates, S W Davies, H Lehrach, E E Wanker. Cell 1997
15

Ataxin-3 binds VCP/p97 and regulates retrotranslocation of ERAD substrates.
Xiaoyan Zhong, Randall N Pittman. Hum Mol Genet 2006
153
15

Flanking polyproline sequences inhibit beta-sheet structure in polyglutamine segments by inducing PPII-like helix structure.
Gregory Darnell, Joseph P R O Orgel, Reinhard Pahl, Stephen C Meredith. J Mol Biol 2007
120
15

The AXH domain adopts alternative folds the solution structure of HBP1 AXH.
Cesira de Chiara, Rajesh P Menon, Salvatore Adinolfi, Jasper de Boer, Eleni Ktistaki, Geoff Kelly, Lesley Calder, Dimitris Kioussis, Annalisa Pastore. Structure 2005
33
27

In-cell aggregation of a polyglutamine-containing chimera is a multistep process initiated by the flanking sequence.
Zoya Ignatova, Ashwani K Thakur, Ronald Wetzel, Lila M Gierasch. J Biol Chem 2007
52
17

Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils.
P J Muchowski, G Schaffar, A Sittler, E E Wanker, M K Hayer-Hartl, F U Hartl. Proc Natl Acad Sci U S A 2000
478
15

Defining the role of ubiquitin-interacting motifs in the polyglutamine disease protein, ataxin-3.
Sarah J Shoesmith Berke, Yaohui Chai, Ginger L Marrs, Hsiang Wen, Henry L Paulson. J Biol Chem 2005
76
15

Structural instability and fibrillar aggregation of non-expanded human ataxin-3 revealed under high pressure and temperature.
Stéphane Marchal, Erlet Shehi, Marie-Cécile Harricane, Paola Fusi, Frédéric Heitz, Paolo Tortora, Reinhard Lange. J Biol Chem 2003
52
17


Opinion: What is the role of protein aggregation in neurodegeneration?
Christopher A Ross, Michelle A Poirier. Nat Rev Mol Cell Biol 2005
445
14


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.