A citation-based method for searching scientific literature

Yoshitaka Nagai, Takashi Inui, H Akiko Popiel, Nobuhiro Fujikake, Kazuhiro Hasegawa, Yoshihiro Urade, Yuji Goto, Hironobu Naiki, Tatsushi Toda. Nat Struct Mol Biol 2007
Times Cited: 239







List of co-cited articles
1470 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004
41

Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism.
Ashwani K Thakur, Murali Jayaraman, Rakesh Mishra, Monika Thakur, Veronique M Chellgren, In-Ja L Byeon, Dalaver H Anjum, Ravindra Kodali, Trevor P Creamer, James F Conway,[...]. Nat Struct Mol Biol 2009
314
33

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
29


Oligoproline effects on polyglutamine conformation and aggregation.
Anusri Bhattacharyya, Ashwani K Thakur, Veronique M Chellgren, Geetha Thiagarajan, Angela D Williams, Brian W Chellgren, Trevor P Creamer, Ronald Wetzel. J Mol Biol 2006
196
26

Identifying polyglutamine protein species in situ that best predict neurodegeneration.
Jason Miller, Montserrat Arrasate, Elizabeth Brooks, Clare Peters Libeu, Justin Legleiter, Danny Hatters, Jessica Curtis, Kenneth Cheung, Preethi Krishnan, Siddhartha Mitra,[...]. Nat Chem Biol 2011
138
25

Secondary structure of Huntingtin amino-terminal region.
Mee Whi Kim, Yogarany Chelliah, Sang Woo Kim, Zbyszek Otwinowski, Ilya Bezprozvanny. Structure 2009
182
24

Soluble polyglutamine oligomers formed prior to inclusion body formation are cytotoxic.
Toshiaki Takahashi, Shinya Kikuchi, Shinichi Katada, Yoshitaka Nagai, Masatoyo Nishizawa, Osamu Onodera. Hum Mol Genet 2008
167
23

Huntington's disease age-of-onset linked to polyglutamine aggregation nucleation.
Songming Chen, Frank A Ferrone, Ronald Wetzel. Proc Natl Acad Sci U S A 2002
397
23

Trinucleotide repeat disorders.
Harry T Orr, Huda Y Zoghbi. Annu Rev Neurosci 2007
995
22

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
21

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo.
E Scherzinger, R Lurz, M Turmaine, L Mangiarini, B Hollenbach, R Hasenbank, G P Bates, S W Davies, H Lehrach, E E Wanker. Cell 1997
21

Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization.
Michelle A Poirier, Huilin Li, Jed Macosko, Shuowei Cai, Mario Amzel, Christopher A Ross. J Biol Chem 2002
281
20


Critical nucleus size for disease-related polyglutamine aggregation is repeat-length dependent.
Karunakar Kar, Murali Jayaraman, Bankanidhi Sahoo, Ravindra Kodali, Ronald Wetzel. Nat Struct Mol Biol 2011
156
20

Unmasking the roles of N- and C-terminal flanking sequences from exon 1 of huntingtin as modulators of polyglutamine aggregation.
Scott L Crick, Kiersten M Ruff, Kanchan Garai, Carl Frieden, Rohit V Pappu. Proc Natl Acad Sci U S A 2013
146
19

Glutamine repeats and neurodegeneration.
H Y Zoghbi, H T Orr. Annu Rev Neurosci 2000
969
18

Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity.
Randy Singh Atwal, Jianrun Xia, Deborah Pinchev, Jillian Taylor, Richard M Epand, Ray Truant. Hum Mol Genet 2007
268
18

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
18

Polyglutamine domain flexibility mediates the proximity between flanking sequences in huntingtin.
Nicholas Stephane Caron, Carly Robyn Desmond, Jianrun Xia, Ray Truant. Proc Natl Acad Sci U S A 2013
94
19

Slow amyloid nucleation via α-helix-rich oligomeric intermediates in short polyglutamine-containing huntingtin fragments.
Murali Jayaraman, Ravindra Kodali, Bankanidhi Sahoo, Ashwani K Thakur, Anand Mayasundari, Rakesh Mishra, Cynthia B Peterson, Ronald Wetzel. J Mol Biol 2012
132
18

Essential role of coiled coils for aggregation and activity of Q/N-rich prions and PolyQ proteins.
Ferdinando Fiumara, Luana Fioriti, Eric R Kandel, Wayne A Hendrickson. Cell 2010
166
18

Mutant huntingtin fragments form oligomers in a polyglutamine length-dependent manner in vitro and in vivo.
Justin Legleiter, Emily Mitchell, Gregor P Lotz, Ellen Sapp, Cheping Ng, Marian DiFiglia, Leslie M Thompson, Paul J Muchowski. J Biol Chem 2010
143
18

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis.
Rakez Kayed, Elizabeth Head, Jennifer L Thompson, Theresa M McIntire, Saskia C Milton, Carl W Cotman, Charles G Glabe. Science 2003
16

Flanking polyproline sequences inhibit beta-sheet structure in polyglutamine segments by inducing PPII-like helix structure.
Gregory Darnell, Joseph P R O Orgel, Reinhard Pahl, Stephen C Meredith. J Mol Biol 2007
123
16

A linear lattice model for polyglutamine in CAG-expansion diseases.
Melanie J Bennett, Kathryn E Huey-Tubman, Andrew B Herr, Anthony P West, Scott A Ross, Pamela J Bjorkman. Proc Natl Acad Sci U S A 2002
109
16


Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology.
E Scherzinger, A Sittler, K Schweiger, V Heiser, R Lurz, R Hasenbank, G P Bates, H Lehrach, E E Wanker. Proc Natl Acad Sci U S A 1999
532
16

Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice.
Xiaofeng Gu, Erin R Greiner, Rakesh Mishra, Ravindra Kodali, Alex Osmand, Steven Finkbeiner, Joan S Steffan, Leslie Michels Thompson, Ronald Wetzel, X William Yang. Neuron 2009
223
15

The first 17 amino acids of Huntingtin modulate its sub-cellular localization, aggregation and effects on calcium homeostasis.
Erica Rockabrand, Natalia Slepko, Antonello Pantalone, Vidya N Nukala, Aleksey Kazantsev, J Lawrence Marsh, Patrick G Sullivan, Joan S Steffan, Stefano L Sensi, Leslie Michels Thompson. Hum Mol Genet 2007
196
15

Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease.
Kirupa Sathasivam, Andreas Neueder, Theresa A Gipson, Christian Landles, Agnesska C Benjamin, Marie K Bondulich, Donna L Smith, Richard L M Faull, Raymund A C Roos, David Howland,[...]. Proc Natl Acad Sci U S A 2013
280
15

Polyglutamine induced misfolding of huntingtin exon1 is modulated by the flanking sequences.
Vinal V Lakhani, Feng Ding, Nikolay V Dokholyan. PLoS Comput Biol 2010
74
20


Inhibition of polyglutamine protein aggregation and cell death by novel peptides identified by phage display screening.
Y Nagai, T Tucker, H Ren, D J Kenan, B S Henderson, J D Keene, W J Strittmatter, J R Burke. J Biol Chem 2000
149
15

The aggregation-enhancing huntingtin N-terminus is helical in amyloid fibrils.
V N Sivanandam, Murali Jayaraman, Cody L Hoop, Ravindra Kodali, Ronald Wetzel, Patrick C A van der Wel. J Am Chem Soc 2011
125
15

Identification of novel potentially toxic oligomers formed in vitro from mammalian-derived expanded huntingtin exon-1 protein.
Leslie G Nucifora, Kathleen A Burke, Xia Feng, Nicolas Arbez, Shanshan Zhu, Jason Miller, Guocheng Yang, Tamara Ratovitski, Michael Delannoy, Paul J Muchowski,[...]. J Biol Chem 2012
74
20

Flanking sequences profoundly alter polyglutamine toxicity in yeast.
Martin L Duennwald, Smitha Jagadish, Paul J Muchowski, Susan Lindquist. Proc Natl Acad Sci U S A 2006
220
14

Inhibiting the nucleation of amyloid structure in a huntingtin fragment by targeting α-helix-rich oligomeric intermediates.
Rakesh Mishra, Murali Jayaraman, Bartholomew P Roland, Elizabeth Landrum, Timothy Fullam, Ravindra Kodali, Ashwani K Thakur, Irene Arduini, Ronald Wetzel. J Mol Biol 2012
65
21

Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells.
Wen Yang, John R Dunlap, Richard B Andrews, Ronald Wetzel. Hum Mol Genet 2002
260
14

Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases.
M F Perutz, T Johnson, M Suzuki, J T Finch. Proc Natl Acad Sci U S A 1994
844
14

Amyloid-like features of polyglutamine aggregates and their assembly kinetics.
Songming Chen, Valerie Berthelier, J Bradley Hamilton, Brian O'Nuallain, Ronald Wetzel. Biochemistry 2002
260
14

The chaperonin TRiC blocks a huntingtin sequence element that promotes the conformational switch to aggregation.
Stephen Tam, Christoph Spiess, William Auyeung, Lukasz Joachimiak, Bryan Chen, Michelle A Poirier, Judith Frydman. Nat Struct Mol Biol 2009
178
14

Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3.
H L Paulson, M K Perez, Y Trottier, J Q Trojanowski, S H Subramony, S S Das, P Vig, J L Mandel, K H Fischbeck, R N Pittman. Neuron 1997
671
13

Prevention of polyglutamine oligomerization and neurodegeneration by the peptide inhibitor QBP1 in Drosophila.
Yoshitaka Nagai, Nobuhiro Fujikake, Katsuhito Ohno, Hiroyuki Higashiyama, Helena A Popiel, Julia Rahadian, Masamitsu Yamaguchi, Warren J Strittmatter, James R Burke, Tatsushi Toda. Hum Mol Genet 2003
105
13

Protein misfolding, functional amyloid, and human disease.
Fabrizio Chiti, Christopher M Dobson. Annu Rev Biochem 2006
13

Mechanism of cis-inhibition of polyQ fibrillation by polyP: PPII oligomers and the hydrophobic effect.
Gregory D Darnell, JohnMark Derryberry, Josh W Kurutz, Stephen C Meredith. Biophys J 2009
42
30

Pathogenic and non-pathogenic polyglutamine tracts have similar structural properties: towards a length-dependent toxicity gradient.
Fabrice A C Klein, Annalisa Pastore, Laura Masino, Gabrielle Zeder-Lutz, Hélène Nierengarten, Mustapha Oulad-Abdelghani, Danièle Altschuh, Jean-Louis Mandel, Yvon Trottier. J Mol Biol 2007
77
16

Structural features and domain organization of huntingtin fibrils.
Charles W Bugg, J Mario Isas, Torsten Fischer, Paul H Patterson, Ralf Langen. J Biol Chem 2012
60
21

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.
Brinda Ravikumar, Coralie Vacher, Zdenek Berger, Janet E Davies, Shouqing Luo, Lourdes G Oroz, Francesco Scaravilli, Douglas F Easton, Rainer Duden, Cahir J O'Kane,[...]. Nat Genet 2004
12

Protein aggregation and neurodegenerative disease.
Christopher A Ross, Michelle A Poirier. Nat Med 2004
12


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.