A citation-based method for searching scientific literature

Yoshitaka Nagai, Takashi Inui, H Akiko Popiel, Nobuhiro Fujikake, Kazuhiro Hasegawa, Yoshihiro Urade, Yuji Goto, Hironobu Naiki, Tatsushi Toda. Nat Struct Mol Biol 2007
Times Cited: 230







List of co-cited articles
1447 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004
40

Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism.
Ashwani K Thakur, Murali Jayaraman, Rakesh Mishra, Monika Thakur, Veronique M Chellgren, In-Ja L Byeon, Dalaver H Anjum, Ravindra Kodali, Trevor P Creamer, James F Conway,[...]. Nat Struct Mol Biol 2009
299
31


Trinucleotide repeat disorders.
Harry T Orr, Huda Y Zoghbi. Annu Rev Neurosci 2007
957
26

Secondary structure of Huntingtin amino-terminal region.
Mee Whi Kim, Yogarany Chelliah, Sang Woo Kim, Zbyszek Otwinowski, Ilya Bezprozvanny. Structure 2009
177
26

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
26

Oligoproline effects on polyglutamine conformation and aggregation.
Anusri Bhattacharyya, Ashwani K Thakur, Veronique M Chellgren, Geetha Thiagarajan, Angela D Williams, Brian W Chellgren, Trevor P Creamer, Ronald Wetzel. J Mol Biol 2006
183
24

Soluble polyglutamine oligomers formed prior to inclusion body formation are cytotoxic.
Toshiaki Takahashi, Shinya Kikuchi, Shinichi Katada, Yoshitaka Nagai, Masatoyo Nishizawa, Osamu Onodera. Hum Mol Genet 2008
161
24

Huntington's disease age-of-onset linked to polyglutamine aggregation nucleation.
Songming Chen, Frank A Ferrone, Ronald Wetzel. Proc Natl Acad Sci U S A 2002
386
23

Identifying polyglutamine protein species in situ that best predict neurodegeneration.
Jason Miller, Montserrat Arrasate, Elizabeth Brooks, Clare Peters Libeu, Justin Legleiter, Danny Hatters, Jessica Curtis, Kenneth Cheung, Preethi Krishnan, Siddhartha Mitra,[...]. Nat Chem Biol 2011
127
23

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo.
E Scherzinger, R Lurz, M Turmaine, L Mangiarini, B Hollenbach, R Hasenbank, G P Bates, S W Davies, H Lehrach, E E Wanker. Cell 1997
984
21

Essential role of coiled coils for aggregation and activity of Q/N-rich prions and PolyQ proteins.
Ferdinando Fiumara, Luana Fioriti, Eric R Kandel, Wayne A Hendrickson. Cell 2010
156
21

Critical nucleus size for disease-related polyglutamine aggregation is repeat-length dependent.
Karunakar Kar, Murali Jayaraman, Bankanidhi Sahoo, Ravindra Kodali, Ronald Wetzel. Nat Struct Mol Biol 2011
141
20

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
19


Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization.
Michelle A Poirier, Huilin Li, Jed Macosko, Shuowei Cai, Mario Amzel, Christopher A Ross. J Biol Chem 2002
274
18

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis.
Rakez Kayed, Elizabeth Head, Jennifer L Thompson, Theresa M McIntire, Saskia C Milton, Carl W Cotman, Charles G Glabe. Science 2003
17

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology.
E Scherzinger, A Sittler, K Schweiger, V Heiser, R Lurz, R Hasenbank, G P Bates, H Lehrach, E E Wanker. Proc Natl Acad Sci U S A 1999
512
17

Glutamine repeats and neurodegeneration.
H Y Zoghbi, H T Orr. Annu Rev Neurosci 2000
951
17

Polyglutamine induced misfolding of huntingtin exon1 is modulated by the flanking sequences.
Vinal V Lakhani, Feng Ding, Nikolay V Dokholyan. PLoS Comput Biol 2010
72
22

Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity.
Randy Singh Atwal, Jianrun Xia, Deborah Pinchev, Jillian Taylor, Richard M Epand, Ray Truant. Hum Mol Genet 2007
250
16


Slow amyloid nucleation via α-helix-rich oligomeric intermediates in short polyglutamine-containing huntingtin fragments.
Murali Jayaraman, Ravindra Kodali, Bankanidhi Sahoo, Ashwani K Thakur, Anand Mayasundari, Rakesh Mishra, Cynthia B Peterson, Ronald Wetzel. J Mol Biol 2012
124
16

Mutant huntingtin fragments form oligomers in a polyglutamine length-dependent manner in vitro and in vivo.
Justin Legleiter, Emily Mitchell, Gregor P Lotz, Ellen Sapp, Cheping Ng, Marian DiFiglia, Leslie M Thompson, Paul J Muchowski. J Biol Chem 2010
137
16

Unmasking the roles of N- and C-terminal flanking sequences from exon 1 of huntingtin as modulators of polyglutamine aggregation.
Scott L Crick, Kiersten M Ruff, Kanchan Garai, Carl Frieden, Rohit V Pappu. Proc Natl Acad Sci U S A 2013
127
16

Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases.
M F Perutz, T Johnson, M Suzuki, J T Finch. Proc Natl Acad Sci U S A 1994
834
15

Amyloid-like features of polyglutamine aggregates and their assembly kinetics.
Songming Chen, Valerie Berthelier, J Bradley Hamilton, Brian O'Nuallain, Ronald Wetzel. Biochemistry 2002
257
15

The chaperonin TRiC blocks a huntingtin sequence element that promotes the conformational switch to aggregation.
Stephen Tam, Christoph Spiess, William Auyeung, Lukasz Joachimiak, Bryan Chen, Michelle A Poirier, Judith Frydman. Nat Struct Mol Biol 2009
170
15

Flanking polyproline sequences inhibit beta-sheet structure in polyglutamine segments by inducing PPII-like helix structure.
Gregory Darnell, Joseph P R O Orgel, Reinhard Pahl, Stephen C Meredith. J Mol Biol 2007
114
15

A linear lattice model for polyglutamine in CAG-expansion diseases.
Melanie J Bennett, Kathryn E Huey-Tubman, Andrew B Herr, Anthony P West, Scott A Ross, Pamela J Bjorkman. Proc Natl Acad Sci U S A 2002
103
15

Inhibition of polyglutamine protein aggregation and cell death by novel peptides identified by phage display screening.
Y Nagai, T Tucker, H Ren, D J Kenan, B S Henderson, J D Keene, W J Strittmatter, J R Burke. J Biol Chem 2000
140
15

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
15

Polyglutamine domain flexibility mediates the proximity between flanking sequences in huntingtin.
Nicholas Stephane Caron, Carly Robyn Desmond, Jianrun Xia, Ray Truant. Proc Natl Acad Sci U S A 2013
82
18


Prevention of polyglutamine oligomerization and neurodegeneration by the peptide inhibitor QBP1 in Drosophila.
Yoshitaka Nagai, Nobuhiro Fujikake, Katsuhito Ohno, Hiroyuki Higashiyama, Helena A Popiel, Julia Rahadian, Masamitsu Yamaguchi, Warren J Strittmatter, James R Burke, Tatsushi Toda. Hum Mol Genet 2003
104
14

Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease.
Kirupa Sathasivam, Andreas Neueder, Theresa A Gipson, Christian Landles, Agnesska C Benjamin, Marie K Bondulich, Donna L Smith, Richard L M Faull, Raymund A C Roos, David Howland,[...]. Proc Natl Acad Sci U S A 2013
244
14

Solution structure of polyglutamine tracts in GST-polyglutamine fusion proteins.
Laura Masino, Geoff Kelly, Kevin Leonard, Yvon Trottier, Annalisa Pastore. FEBS Lett 2002
122
13

Protein misfolding, functional amyloid, and human disease.
Fabrizio Chiti, Christopher M Dobson. Annu Rev Biochem 2006
13

The aggregation-enhancing huntingtin N-terminus is helical in amyloid fibrils.
V N Sivanandam, Murali Jayaraman, Cody L Hoop, Ravindra Kodali, Ronald Wetzel, Patrick C A van der Wel. J Am Chem Soc 2011
114
13

Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice.
Xiaofeng Gu, Erin R Greiner, Rakesh Mishra, Ravindra Kodali, Alex Osmand, Steven Finkbeiner, Joan S Steffan, Leslie Michels Thompson, Ronald Wetzel, X William Yang. Neuron 2009
210
13

Flanking sequences profoundly alter polyglutamine toxicity in yeast.
Martin L Duennwald, Smitha Jagadish, Paul J Muchowski, Susan Lindquist. Proc Natl Acad Sci U S A 2006
210
13

The first 17 amino acids of Huntingtin modulate its sub-cellular localization, aggregation and effects on calcium homeostasis.
Erica Rockabrand, Natalia Slepko, Antonello Pantalone, Vidya N Nukala, Aleksey Kazantsev, J Lawrence Marsh, Patrick G Sullivan, Joan S Steffan, Stefano L Sensi, Leslie Michels Thompson. Hum Mol Genet 2007
186
13

Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells.
Wen Yang, John R Dunlap, Richard B Andrews, Ronald Wetzel. Hum Mol Genet 2002
252
13

Pathogenic and non-pathogenic polyglutamine tracts have similar structural properties: towards a length-dependent toxicity gradient.
Fabrice A C Klein, Annalisa Pastore, Laura Masino, Gabrielle Zeder-Lutz, Hélène Nierengarten, Mustapha Oulad-Abdelghani, Danièle Altschuh, Jean-Louis Mandel, Yvon Trottier. J Mol Biol 2007
74
17

Identification of novel potentially toxic oligomers formed in vitro from mammalian-derived expanded huntingtin exon-1 protein.
Leslie G Nucifora, Kathleen A Burke, Xia Feng, Nicolas Arbez, Shanshan Zhu, Jason Miller, Guocheng Yang, Tamara Ratovitski, Michael Delannoy, Paul J Muchowski,[...]. J Biol Chem 2012
68
19

Fluorescence correlation spectroscopy shows that monomeric polyglutamine molecules form collapsed structures in aqueous solutions.
Scott L Crick, Murali Jayaraman, Carl Frieden, Ronald Wetzel, Rohit V Pappu. Proc Natl Acad Sci U S A 2006
197
12

Characterizing the conformational ensemble of monomeric polyglutamine.
Xiaoling Wang, Andreas Vitalis, Matthew A Wyczalkowski, Rohit V Pappu. Proteins 2006
103
12

A compact beta model of huntingtin toxicity.
Qi Charles Zhang, Tzu-Lan Yeh, Alfonso Leyva, Leslie G Frank, Jason Miller, Yujin E Kim, Ralf Langen, Steven Finkbeiner, Mario L Amzel, Christopher A Ross,[...]. J Biol Chem 2011
43
27

Monoclonal antibodies recognize distinct conformational epitopes formed by polyglutamine in a mutant huntingtin fragment.
Justin Legleiter, Gregor P Lotz, Jason Miller, Jan Ko, Cheping Ng, Geneva L Williams, Steve Finkbeiner, Paul H Patterson, Paul J Muchowski. J Biol Chem 2009
74
16

Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3.
H L Paulson, M K Perez, Y Trottier, J Q Trojanowski, S H Subramony, S S Das, P Vig, J L Mandel, K H Fischbeck, R N Pittman. Neuron 1997
654
12


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.