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Times Cited: 3093
Times Cited: 3093
Times Cited
Times Co-cited
Similarity
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
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Small CRISPR RNAs guide antiviral defense in prokaryotes.
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Multiplex genome engineering using CRISPR/Cas systems.
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Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants.
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C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector.
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Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system.
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CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity.
Janice S Chen, Enbo Ma, Lucas B Harrington, Maria Da Costa, Xinran Tian, Joel M Palefsky, Jennifer A Doudna. Science 2018
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CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNA.
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Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements.
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Nucleic acid detection with CRISPR-Cas13a/C2c2.
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The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA.
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Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6.
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An updated evolutionary classification of CRISPR-Cas systems.
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CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III.
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RNA editing with CRISPR-Cas13.
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Identification of genes that are associated with DNA repeats in prokaryotes.
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Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin.
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RNA targeting with CRISPR-Cas13.
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Development and applications of CRISPR-Cas9 for genome engineering.
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Field-deployable viral diagnostics using CRISPR-Cas13.
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15
Search-and-replace genome editing without double-strand breaks or donor DNA.
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CRISPR elements in Yersinia pestis acquire new repeats by preferential uptake of bacteriophage DNA, and provide additional tools for evolutionary studies.
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Diversity, classification and evolution of CRISPR-Cas systems.
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SHERLOCK: nucleic acid detection with CRISPR nucleases.
Max J Kellner, Jeremy G Koob, Jonathan S Gootenberg, Omar O Abudayyeh, Feng Zhang. Nat Protoc 2019
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In vivo genome editing using Staphylococcus aureus Cas9.
F Ann Ran, Le Cong, Winston X Yan, David A Scott, Jonathan S Gootenberg, Andrea J Kriz, Bernd Zetsche, Ophir Shalem, Xuebing Wu, Kira S Makarova,[...]. Nature 2015
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DNA targeting specificity of RNA-guided Cas9 nucleases.
Patrick D Hsu, David A Scott, Joshua A Weinstein, F Ann Ran, Silvana Konermann, Vineeta Agarwala, Yinqing Li, Eli J Fine, Xuebing Wu, Ophir Shalem,[...]. Nat Biotechnol 2013
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Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems.
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Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection.
Alexandra East-Seletsky, Mitchell R O'Connell, Spencer C Knight, David Burstein, Jamie H D Cate, Robert Tjian, Jennifer A Doudna. Nature 2016
Alexandra East-Seletsky, Mitchell R O'Connell, Spencer C Knight, David Burstein, Jamie H D Cate, Robert Tjian, Jennifer A Doudna. Nature 2016
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Rationally engineered Cas9 nucleases with improved specificity.
Ian M Slaymaker, Linyi Gao, Bernd Zetsche, David A Scott, Winston X Yan, Feng Zhang. Science 2016
Ian M Slaymaker, Linyi Gao, Bernd Zetsche, David A Scott, Winston X Yan, Feng Zhang. Science 2016
13
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes.
Lucas B Harrington, David Burstein, Janice S Chen, David Paez-Espino, Enbo Ma, Isaac P Witte, Joshua C Cofsky, Nikos C Kyrpides, Jillian F Banfield, Jennifer A Doudna. Science 2018
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Evolution and classification of the CRISPR-Cas systems.
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Crystal structure of Cas9 in complex with guide RNA and target DNA.
Hiroshi Nishimasu, F Ann Ran, Patrick D Hsu, Silvana Konermann, Soraya I Shehata, Naoshi Dohmae, Ryuichiro Ishitani, Feng Zhang, Osamu Nureki. Cell 2014
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Phage response to CRISPR-encoded resistance in Streptococcus thermophilus.
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CRISPR/Cas Systems towards Next-Generation Biosensing.
Yi Li, Shiyuan Li, Jin Wang, Guozhen Liu. Trends Biotechnol 2019
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CRISPR-Cas12-based detection of SARS-CoV-2.
James P Broughton, Xianding Deng, Guixia Yu, Clare L Fasching, Venice Servellita, Jasmeet Singh, Xin Miao, Jessica A Streithorst, Andrea Granados, Alicia Sotomayor-Gonzalez,[...]. Nat Biotechnol 2020
James P Broughton, Xianding Deng, Guixia Yu, Clare L Fasching, Venice Servellita, Jasmeet Singh, Xin Miao, Jessica A Streithorst, Andrea Granados, Alicia Sotomayor-Gonzalez,[...]. Nat Biotechnol 2020
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Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors.
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High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.
Benjamin P Kleinstiver, Vikram Pattanayak, Michelle S Prew, Shengdar Q Tsai, Nhu T Nguyen, Zongli Zheng, J Keith Joung. Nature 2016
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Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.
Lei S Qi, Matthew H Larson, Luke A Gilbert, Jennifer A Doudna, Jonathan S Weissman, Adam P Arkin, Wendell A Lim. Cell 2013
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CRISPR-Cas12a-assisted nucleic acid detection.
Shi-Yuan Li, Qiu-Xiang Cheng, Jing-Man Wang, Xiao-Yan Li, Zi-Long Zhang, Song Gao, Rui-Bing Cao, Guo-Ping Zhao, Jin Wang. Cell Discov 2018
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Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune system.
Joe Bondy-Denomy, April Pawluk, Karen L Maxwell, Alan R Davidson. Nature 2013
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Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
Nicole M Gaudelli, Alexis C Komor, Holly A Rees, Michael S Packer, Ahmed H Badran, David I Bryson, David R Liu. Nature 2017
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Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.
Alexis C Komor, Yongjoo B Kim, Michael S Packer, John A Zuris, David R Liu. Nature 2016
Alexis C Komor, Yongjoo B Kim, Michael S Packer, John A Zuris, David R Liu. Nature 2016
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The next generation of CRISPR-Cas technologies and applications.
Adrian Pickar-Oliver, Charles A Gersbach. Nat Rev Mol Cell Biol 2019
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Improving CRISPR-Cas nuclease specificity using truncated guide RNAs.
Yanfang Fu, Jeffry D Sander, Deepak Reyon, Vincent M Cascio, J Keith Joung. Nat Biotechnol 2014
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Engineered CRISPR-Cas9 nucleases with altered PAM specificities.
Benjamin P Kleinstiver, Michelle S Prew, Shengdar Q Tsai, Ved V Topkar, Nhu T Nguyen, Zongli Zheng, Andrew P W Gonzales, Zhuyun Li, Randall T Peterson, Jing-Ruey Joanna Yeh,[...]. Nature 2015
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10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.