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Times Cited
Times Co-cited
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Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons.
Makiko Nagai, Diane B Re, Tetsuya Nagata, Alcmène Chalazonitis, Thomas M Jessell, Hynek Wichterle, Serge Przedborski. Nat Neurosci 2007
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Astrocytes from familial and sporadic ALS patients are toxic to motor neurons.
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Neurotoxic reactive astrocytes are induced by activated microglia.
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Francesco Paolo Di Giorgio, Gabriella L Boulting, Samuel Bobrowicz, Kevin C Eggan. Cell Stem Cell 2008
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Hristelina Ilieva, Magdalini Polymenidou, Don W Cleveland. J Cell Biol 2009
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Amyotrophic lateral sclerosis patient iPSC-derived astrocytes impair autophagy via non-cell autonomous mechanisms.
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Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS.
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TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis.
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Hynek Wichterle, Ivo Lieberam, Jeffery A Porter, Thomas M Jessell. Cell 2002
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ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.
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Laura Ferraiuolo, Adrian Higginbottom, Paul R Heath, Sian Barber, David Greenald, Janine Kirby, Pamela J Shaw. Brain 2011
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Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo.
Sophia T Papadeas, Sarah E Kraig, Colin O'Banion, Angelo C Lepore, Nicholas J Maragakis. Proc Natl Acad Sci U S A 2011
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Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants.
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Expression of ALS-linked TDP-43 mutant in astrocytes causes non-cell-autonomous motor neuron death in rats.
Jianbin Tong, Cao Huang, Fangfang Bi, Qinxue Wu, Bo Huang, Xionghao Liu, Fang Li, Hongxia Zhou, Xu-Gang Xia. EMBO J 2013
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Astrocyte loss of mutant SOD1 delays ALS disease onset and progression in G85R transgenic mice.
Lijun Wang, David H Gutmann, Raymond P Roos. Hum Mol Genet 2011
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A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models.
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Reactive Astrocytes Promote ALS-like Degeneration and Intracellular Protein Aggregation in Human Motor Neurons by Disrupting Autophagy through TGF-β1.
Pratibha Tripathi, Natalia Rodriguez-Muela, Joseph R Klim, A Sophie de Boer, Sahil Agrawal, Jackson Sandoe, Claudia S Lopes, Karolyn Sassi Ogliari, Luis A Williams, Matthew Shear,[...]. Stem Cell Reports 2017
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ALS: a disease of motor neurons and their nonneuronal neighbors.
Séverine Boillée, Christine Vande Velde, Don W Cleveland. Neuron 2006
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Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1.
Evangelos Kiskinis, Jackson Sandoe, Luis A Williams, Gabriella L Boulting, Rob Moccia, Brian J Wainger, Steve Han, Theodore Peng, Sebastian Thams, Shravani Mikkilineni,[...]. Cell Stem Cell 2014
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Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS.
Claire E Hall, Zhi Yao, Minee Choi, Giulia E Tyzack, Andrea Serio, Raphaelle Luisier, Jasmine Harley, Elisavet Preza, Charlie Arber, Sarah J Crisp,[...]. Cell Rep 2017
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Human iPSC-derived astrocytes from ALS patients with mutated C9ORF72 show increased oxidative stress and neurotoxicity.
Anastasya Birger, Israel Ben-Dor, Miri Ottolenghi, Tikva Turetsky, Yaniv Gil, Sahar Sweetat, Liat Perez, Vitali Belzer, Natania Casden, Debora Steiner,[...]. EBioMedicine 2019
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Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6.
Caroline Vance, Boris Rogelj, Tibor Hortobágyi, Kurt J De Vos, Agnes Lumi Nishimura, Jemeen Sreedharan, Xun Hu, Bradley Smith, Deborah Ruddy, Paul Wright,[...]. Science 2009
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A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model.
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Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice.
A M Clement, M D Nguyen, E A Roberts, M L Garcia, S Boillée, M Rule, A P McMahon, W Doucette, D Siwek, R J Ferrante,[...]. Science 2003
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Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis.
David R Beers, Jenny S Henkel, Qin Xiao, Weihua Zhao, Jinghong Wang, Albert A Yen, Laszlo Siklos, Scott R McKercher, Stanley H Appel. Proc Natl Acad Sci U S A 2006
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Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS).
David S Howland, Jian Liu, Yijin She, Beth Goad, Nicholas J Maragakis, Benjamin Kim, Jamie Erickson, John Kulik, Lisa DeVito, George Psaltis,[...]. Proc Natl Acad Sci U S A 2002
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Astrocyte-derived TGF-β1 accelerates disease progression in ALS mice by interfering with the neuroprotective functions of microglia and T cells.
Fumito Endo, Okiru Komine, Noriko Fujimori-Tonou, Masahisa Katsuno, Shijie Jin, Seiji Watanabe, Gen Sobue, Mari Dezawa, Tony Wyss-Coray, Koji Yamanaka. Cell Rep 2015
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Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons.
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A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.
Hadas Keren-Shaul, Amit Spinrad, Assaf Weiner, Orit Matcovitch-Natan, Raz Dvir-Szternfeld, Tyler K Ulland, Eyal David, Kuti Baruch, David Lara-Astaiso, Beata Toth,[...]. Cell 2017
Hadas Keren-Shaul, Amit Spinrad, Assaf Weiner, Orit Matcovitch-Natan, Raz Dvir-Szternfeld, Tyler K Ulland, Eyal David, Kuti Baruch, David Lara-Astaiso, Beata Toth,[...]. Cell 2017
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Micro-RNAs secreted through astrocyte-derived extracellular vesicles cause neuronal network degeneration in C9orf72 ALS.
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Mutant C9orf72 human iPSC-derived astrocytes cause non-cell autonomous motor neuron pathophysiology.
Chen Zhao, Anna-Claire Devlin, Amit K Chouhan, Bhuvaneish T Selvaraj, Maria Stavrou, Karen Burr, Veronica Brivio, Xin He, Arpan R Mehta, David Story,[...]. Glia 2020
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Phenotypically aberrant astrocytes that promote motoneuron damage in a model of inherited amyotrophic lateral sclerosis.
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Pablo Díaz-Amarilla, Silvia Olivera-Bravo, Emiliano Trias, Andrea Cragnolini, Laura Martínez-Palma, Patricia Cassina, Joseph Beckman, Luis Barbeito. Proc Natl Acad Sci U S A 2011
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State of play in amyotrophic lateral sclerosis genetics.
Alan E Renton, Adriano Chiò, Bryan J Traynor. Nat Neurosci 2014
Alan E Renton, Adriano Chiò, Bryan J Traynor. Nat Neurosci 2014
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Intricate interplay between astrocytes and motor neurons in ALS.
Hemali P Phatnani, Paolo Guarnieri, Brad A Friedman, Monica A Carrasco, Michael Muratet, Sean O'Keeffe, Chiamaka Nwakeze, Florencia Pauli-Behn, Kimberly M Newberry, Sarah K Meadows,[...]. Proc Natl Acad Sci U S A 2013
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Connexin 43 in astrocytes contributes to motor neuron toxicity in amyotrophic lateral sclerosis.
Akshata A Almad, Arpitha Doreswamy, Sarah K Gross, Jean-Philippe Richard, Yuqing Huo, Norman Haughey, Nicholas J Maragakis. Glia 2016
Akshata A Almad, Arpitha Doreswamy, Sarah K Gross, Jean-Philippe Richard, Yuqing Huo, Norman Haughey, Nicholas J Maragakis. Glia 2016
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Amyotrophic lateral sclerosis.
Matthew C Kiernan, Steve Vucic, Benjamin C Cheah, Martin R Turner, Andrew Eisen, Orla Hardiman, James R Burrell, Margaret C Zoing. Lancet 2011
Matthew C Kiernan, Steve Vucic, Benjamin C Cheah, Martin R Turner, Andrew Eisen, Orla Hardiman, James R Burrell, Margaret C Zoing. Lancet 2011
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.