A citation-based method for searching scientific literature

Linda S Kaltenbach, Eliana Romero, Robert R Becklin, Rakesh Chettier, Russell Bell, Amit Phansalkar, Andrew Strand, Cameron Torcassi, Justin Savage, Anthony Hurlburt, Guang-Ho Cha, Lubna Ukani, Cindy Lou Chepanoske, Yuejun Zhen, Sudhir Sahasrabudhe, James Olson, Cornelia Kurschner, Lisa M Ellerby, John M Peltier, Juan Botas, Robert E Hughes. PLoS Genet 2007
Times Cited: 292







List of co-cited articles
1272 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



Network organization of the huntingtin proteomic interactome in mammalian brain.
Dyna I Shirasaki, Erin R Greiner, Ismael Al-Ramahi, Michelle Gray, Pinmanee Boontheung, Daniel H Geschwind, Juan Botas, Giovanni Coppola, Steve Horvath, Joseph A Loo,[...]. Neuron 2012
188
33

Proteomic analysis of wild-type and mutant huntingtin-associated proteins in mouse brains identifies unique interactions and involvement in protein synthesis.
Brady P Culver, Jeffrey N Savas, Sung K Park, Jeong H Choi, Shuqiu Zheng, Scott O Zeitlin, John R Yates, Naoko Tanese. J Biol Chem 2012
85
29

The Biology of Huntingtin.
Frédéric Saudou, Sandrine Humbert. Neuron 2016
418
22


Huntington's disease: from molecular pathogenesis to clinical treatment.
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
964
20

Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice.
Peter Langfelder, Jeffrey P Cantle, Doxa Chatzopoulou, Nan Wang, Fuying Gao, Ismael Al-Ramahi, Xiao-Hong Lu, Eliana Marisa Ramos, Karla El-Zein, Yining Zhao,[...]. Nat Neurosci 2016
203
19

Huntingtin protein interactions altered by polyglutamine expansion as determined by quantitative proteomic analysis.
Tamara Ratovitski, Ekaterine Chighladze, Nicolas Arbez, Tatiana Boronina, Shelley Herbrich, Robert N Cole, Christopher A Ross. Cell Cycle 2012
77
23

Huntington disease.
J P Vonsattel, M DiFiglia. J Neuropathol Exp Neurol 1998
16

Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1.
Tie-Shan Tang, Huiping Tu, Edmond Y W Chan, Anton Maximov, Zhengnan Wang, Cheryl L Wellington, Michael R Hayden, Ilya Bezprozvanny. Neuron 2003
363
16

A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.
Heike Goehler, Maciej Lalowski, Ulrich Stelzl, Stephanie Waelter, Martin Stroedicke, Uwe Worm, Anja Droege, Katrin S Lindenberg, Maria Knoblich, Christian Haenig,[...]. Mol Cell 2004
318
16

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
14

A large scale Huntingtin protein interaction network implicates Rho GTPase signaling pathways in Huntington disease.
Cendrine Tourette, Biao Li, Russell Bell, Shannon O'Hare, Linda S Kaltenbach, Sean D Mooney, Robert E Hughes. J Biol Chem 2014
57
24

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.
J S Steffan, A Kazantsev, O Spasic-Boskovic, M Greenwald, Y Z Zhu, H Gohler, E E Wanker, G P Bates, D E Housman, L M Thompson. Proc Natl Acad Sci U S A 2000
795
13

Potential function for the Huntingtin protein as a scaffold for selective autophagy.
Joseph Ochaba, Tamás Lukacsovich, George Csikos, Shuqiu Zheng, Julia Margulis, Lisa Salazar, Kai Mao, Alice L Lau, Sylvia Y Yeung, Sandrine Humbert,[...]. Proc Natl Acad Sci U S A 2014
174
13


Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes.
J Nasir, S B Floresco, J R O'Kusky, V M Diewert, J M Richman, J Zeisler, A Borowski, J D Marth, A G Phillips, M R Hayden. Cell 1995
604
12


Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
11

Huntingtin modulates transcription, occupies gene promoters in vivo, and binds directly to DNA in a polyglutamine-dependent manner.
Caroline L Benn, Tingting Sun, Ghazaleh Sadri-Vakili, Karen N McFarland, Derek P DiRocco, George J Yohrling, Timothy W Clark, Bérengère Bouzou, Jang-Ho J Cha. J Neurosci 2008
136
11

Huntingtin interacts with a family of WW domain proteins.
P W Faber, G T Barnes, J Srinidhi, J Chen, J F Gusella, M E MacDonald. Hum Mol Genet 1998
306
11

Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease.
Tie-Shan Tang, Elizabeth Slow, Vitalie Lupu, Irina G Stavrovskaya, Mutsuyuki Sugimori, Rodolfo Llinás, Bruce S Kristal, Michael R Hayden, Ilya Bezprozvanny. Proc Natl Acad Sci U S A 2005
282
11

Suppression of neurodegeneration and increased neurotransmission caused by expanded full-length huntingtin accumulating in the cytoplasm.
Eliana Romero, Guang-Ho Cha, Patrik Verstreken, Cindy V Ly, Robert E Hughes, Hugo J Bellen, Juan Botas. Neuron 2008
110
10

Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats.
Liliana B Menalled, Jessica D Sison, Ioannis Dragatsis, Scott Zeitlin, Marie-Françoise Chesselet. J Comp Neurol 2003
341
10

Regional and cellular gene expression changes in human Huntington's disease brain.
Angela Hodges, Andrew D Strand, Aaron K Aragaki, Alexandre Kuhn, Thierry Sengstag, Gareth Hughes, Lyn A Elliston, Cathy Hartog, Darlene R Goldstein, Doris Thu,[...]. Hum Mol Genet 2006
540
10

Molecular mechanisms and potential therapeutical targets in Huntington's disease.
Chiara Zuccato, Marta Valenza, Elena Cattaneo. Physiol Rev 2010
572
10

Neuropathological classification of Huntington's disease.
J P Vonsattel, R H Myers, T J Stevens, R J Ferrante, E D Bird, E P Richardson. J Neuropathol Exp Neurol 1985
10

Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease.
Melinda M Zeron, Oskar Hansson, Nansheng Chen, Cheryl L Wellington, Blair R Leavitt, Patrik Brundin, Michael R Hayden, Lynn A Raymond. Neuron 2002
455
10

Huntingtin functions as a scaffold for selective macroautophagy.
Yan-Ning Rui, Zhen Xu, Bindi Patel, Zhihua Chen, Dongsheng Chen, Antonio Tito, Gabriela David, Yamin Sun, Erin F Stimming, Hugo J Bellen,[...]. Nat Cell Biol 2015
259
10

Enhanced Store-Operated Calcium Entry Leads to Striatal Synaptic Loss in a Huntington's Disease Mouse Model.
Jun Wu, Daniel A Ryskamp, Xia Liang, Polina Egorova, Olga Zakharova, Gene Hung, Ilya Bezprozvanny. J Neurosci 2016
89
11

The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves Huntingtin phosphorylation by Akt.
Sandrine Humbert, Elzbieta A Bryson, Fabrice P Cordelières, Nathan C Connors, Sandeep R Datta, Steven Finkbeiner, Michael E Greenberg, Frédéric Saudou. Dev Cell 2002
367
9

Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease.
Anthone W Dunah, Hyunkyung Jeong, April Griffin, Yong-Man Kim, David G Standaert, Steven M Hersch, M Maral Mouradian, Anne B Young, Naoko Tanese, Dimitri Krainc. Science 2002
538
9

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
9

Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin.
Shu-ichi Okamoto, Mahmoud A Pouladi, Maria Talantova, Dongdong Yao, Peng Xia, Dagmar E Ehrnhoefer, Rameez Zaidi, Arjay Clemente, Marcus Kaul, Rona K Graham,[...]. Nat Med 2009
315
9

Beyond the brain: widespread pathology in Huntington's disease.
Jorien M M van der Burg, Maria Björkqvist, Patrik Brundin. Lancet Neurol 2009
225
9

Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease.
Marta Martinez-Vicente, Zsolt Talloczy, Esther Wong, Guomei Tang, Hiroshi Koga, Susmita Kaushik, Rosa de Vries, Esperanza Arias, Spike Harris, David Sulzer,[...]. Nat Neurosci 2010
564
9

Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue.
S Zeitlin, J P Liu, D L Chapman, V E Papaioannou, A Efstratiadis. Nat Genet 1995
573
9

Huntington disease.
Gillian P Bates, Ray Dorsey, James F Gusella, Michael R Hayden, Chris Kay, Blair R Leavitt, Martha Nance, Christopher A Ross, Rachael I Scahill, Ronald Wetzel,[...]. Nat Rev Dis Primers 2015
653
9

Neuroprotective effects of inositol 1,4,5-trisphosphate receptor C-terminal fragment in a Huntington's disease mouse model.
Tie-Shan Tang, Caixia Guo, Hongyu Wang, Xi Chen, Ilya Bezprozvanny. J Neurosci 2009
77
11

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004
9

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila.
J S Steffan, L Bodai, J Pallos, M Poelman, A McCampbell, B L Apostol, A Kazantsev, E Schmidt, Y Z Zhu, M Greenwald,[...]. Nature 2001
912
8

Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.
Libin Cui, Hyunkyung Jeong, Fran Borovecki, Christopher N Parkhurst, Naoko Tanese, Dimitri Krainc. Cell 2006
763
8

Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release.
Yeun Su Choo, Gail V W Johnson, Marcy MacDonald, Peter J Detloff, Mathieu Lesort. Hum Mol Genet 2004
358
8

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes.
Chiara Zuccato, Marzia Tartari, Andrea Crotti, Donato Goffredo, Marta Valenza, Luciano Conti, Tiziana Cataudella, Blair R Leavitt, Michael R Hayden, Tõnis Timmusk,[...]. Nat Genet 2003
662
8

Huntingtin facilitates dynein/dynactin-mediated vesicle transport.
Juliane P Caviston, Jennifer L Ross, Sheila M Antony, Mariko Tokito, Erika L F Holzbaur. Proc Natl Acad Sci U S A 2007
204
8

Huntingtin proteolysis releases non-polyQ fragments that cause toxicity through dynamin 1 dysregulation.
Marie-Thérèse El-Daher, Emilie Hangen, Julie Bruyère, Ghislaine Poizat, Ismael Al-Ramahi, Raul Pardo, Nicolas Bourg, Sylvie Souquere, Céline Mayet, Gérard Pierron,[...]. EMBO J 2015
59
13

Cytoscape: a software environment for integrated models of biomolecular interaction networks.
Paul Shannon, Andrew Markiel, Owen Ozier, Nitin S Baliga, Jonathan T Wang, Daniel Ramage, Nada Amin, Benno Schwikowski, Trey Ideker. Genome Res 2003
8

Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons.
M DiFiglia, E Sapp, K Chase, C Schwarz, A Meloni, C Young, E Martin, J P Vonsattel, R Carraway, S A Reeves. Neuron 1995
575
8

Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease.
Kirupa Sathasivam, Andreas Neueder, Theresa A Gipson, Christian Landles, Agnesska C Benjamin, Marie K Bondulich, Donna L Smith, Richard L M Faull, Raymund A C Roos, David Howland,[...]. Proc Natl Acad Sci U S A 2013
285
8



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.