A citation-based method for searching scientific literature

Alexandre Kuhn, Darlene R Goldstein, Angela Hodges, Andrew D Strand, Thierry Sengstag, Charles Kooperberg, Kristina Becanovic, Mahmoud A Pouladi, Kirupa Sathasivam, Jang-Ho J Cha, Anthony J Hannan, Michael R Hayden, Blair R Leavitt, Stephen B Dunnett, Robert J Ferrante, Roger Albin, Peggy Shelbourne, Mauro Delorenzi, Sarah J Augood, Richard L M Faull, James M Olson, Gillian P Bates, Lesley Jones, Ruth Luthi-Carter. Hum Mol Genet 2007
Times Cited: 255







List of co-cited articles
1334 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Regional and cellular gene expression changes in human Huntington's disease brain.
Angela Hodges, Andrew D Strand, Aaron K Aragaki, Alexandre Kuhn, Thierry Sengstag, Gareth Hughes, Lyn A Elliston, Cathy Hartog, Darlene R Goldstein, Doris Thu,[...]. Hum Mol Genet 2006
531
52


Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
34

What have we learned from gene expression profiles in Huntington's disease?
Tamara Seredenina, Ruth Luthi-Carter. Neurobiol Dis 2012
100
29

Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice.
Peter Langfelder, Jeffrey P Cantle, Doxa Chatzopoulou, Nan Wang, Fuying Gao, Ismael Al-Ramahi, Xiao-Hong Lu, Eliana Marisa Ramos, Karla El-Zein, Yining Zhao,[...]. Nat Neurosci 2016
197
26

Decreased expression of striatal signaling genes in a mouse model of Huntington's disease.
R Luthi-Carter, A Strand, N L Peters, S M Solano, Z R Hollingsworth, A S Menon, A S Frey, B S Spektor, E B Penney, G Schilling,[...]. Hum Mol Genet 2000
566
25

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
24

Neuropathological classification of Huntington's disease.
J P Vonsattel, R H Myers, T J Stevens, R J Ferrante, E D Bird, E P Richardson. J Neuropathol Exp Neurol 1985
24

Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease.
Kirupa Sathasivam, Andreas Neueder, Theresa A Gipson, Christian Landles, Agnesska C Benjamin, Marie K Bondulich, Donna L Smith, Richard L M Faull, Raymund A C Roos, David Howland,[...]. Proc Natl Acad Sci U S A 2013
278
22

Huntington's disease: from molecular pathogenesis to clinical treatment.
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
945
21

Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease.
Elizabeth J Slow, Jeremy van Raamsdonk, Daniel Rogers, Sarah H Coleman, Rona K Graham, Yu Deng, Rosemary Oh, Nagat Bissada, Sazzad M Hossain, Yu-Zhou Yang,[...]. Hum Mol Genet 2003
590
19

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.
J S Steffan, A Kazantsev, O Spasic-Boskovic, M Greenwald, Y Z Zhu, H Gohler, E E Wanker, G P Bates, D E Housman, L M Thompson. Proc Natl Acad Sci U S A 2000
790
18

Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats.
Liliana B Menalled, Jessica D Sison, Ioannis Dragatsis, Scott Zeitlin, Marie-Françoise Chesselet. J Comp Neurol 2003
337
18

Huntington disease.
J P Vonsattel, M DiFiglia. J Neuropathol Exp Neurol 1998
18

Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice.
Michelle Gray, Dyna I Shirasaki, Carlos Cepeda, Véronique M André, Brian Wilburn, Xiao-Hong Lu, Jifang Tao, Irene Yamazaki, Shi-Hua Li, Yi E Sun,[...]. J Neurosci 2008
446
17

Targeting H3K4 trimethylation in Huntington disease.
Malini Vashishtha, Christopher W Ng, Ferah Yildirim, Theresa A Gipson, Ian H Kratter, Laszlo Bodai, Wan Song, Alice Lau, Adam Labadorf, Annie Vogel-Ciernia,[...]. Proc Natl Acad Sci U S A 2013
101
16

Molecular mechanisms and potential therapeutical targets in Huntington's disease.
Chiara Zuccato, Marta Valenza, Elena Cattaneo. Physiol Rev 2010
568
16

Neurological abnormalities in a knock-in mouse model of Huntington's disease.
C H Lin, S Tallaksen-Greene, W M Chien, J A Cearley, W S Jackson, A B Crouse, S Ren, X J Li, R L Albin, P J Detloff. Hum Mol Genet 2001
445
15

Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.
Libin Cui, Hyunkyung Jeong, Fran Borovecki, Christopher N Parkhurst, Naoko Tanese, Dimitri Krainc. Cell 2006
759
14

Proteolysis of mutant huntingtin produces an exon 1 fragment that accumulates as an aggregated protein in neuronal nuclei in Huntington disease.
Christian Landles, Kirupa Sathasivam, Andreas Weiss, Ben Woodman, Hilary Moffitt, Steve Finkbeiner, Banghua Sun, Juliette Gafni, Lisa M Ellerby, Yvon Trottier,[...]. J Biol Chem 2010
220
14

The Hdh(Q150/Q150) knock-in mouse model of HD and the R6/2 exon 1 model develop comparable and widespread molecular phenotypes.
Ben Woodman, Rachel Butler, Christian Landles, Michelle K Lupton, Jamie Tse, Emma Hockly, Hilary Moffitt, Kirupa Sathasivam, Gillian P Bates. Brain Res Bull 2007
121
14

Transcriptional changes in Huntington disease identified using genome-wide expression profiling and cross-platform analysis.
Kristina Becanovic, Mahmoud A Pouladi, Raymond S Lim, Alexandre Kuhn, Paul Pavlidis, Ruth Luthi-Carter, Michael R Hayden, Blair R Leavitt. Hum Mol Genet 2010
69
20

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity.
F C Nucifora , M Sasaki, M F Peters, H Huang, J K Cooper, M Yamada, H Takahashi, S Tsuji, J Troncoso, V L Dawson,[...]. Science 2001
820
14

Selective deficits in the expression of striatal-enriched mRNAs in Huntington's disease.
Paula A Desplats, Kristi E Kass, Tim Gilmartin, Gregg D Stanwood, Elliott L Woodward, Steven R Head, J Gregor Sutcliffe, Elizabeth A Thomas. J Neurochem 2006
105
13

Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain.
Ruth Luthi-Carter, Sarah A Hanson, Andrew D Strand, Donald A Bergstrom, Wanjoo Chun, Nikki L Peters, Annette M Woods, Edmond Y Chan, Charles Kooperberg, Dimitri Krainc,[...]. Hum Mol Genet 2002
297
13

Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology.
C A Gutekunst, S H Li, H Yi, J S Mulroy, S Kuemmerle, R Jones, D Rye, R J Ferrante, S M Hersch, X J Li. J Neurosci 1999
623
13

Huntington disease: natural history, biomarkers and prospects for therapeutics.
Christopher A Ross, Elizabeth H Aylward, Edward J Wild, Douglas R Langbehn, Jeffrey D Long, John H Warner, Rachael I Scahill, Blair R Leavitt, Julie C Stout, Jane S Paulsen,[...]. Nat Rev Neurol 2014
560
13

Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene.
J H Cha, C M Kosinski, J A Kerner, S A Alsdorf, L Mangiarini, S W Davies, J B Penney, G P Bates, A B Young. Proc Natl Acad Sci U S A 1998
414
12

Genomic landscape of transcriptional and epigenetic dysregulation in early onset polyglutamine disease.
Luis M Valor, Deisy Guiretti, Jose P Lopez-Atalaya, Angel Barco. J Neurosci 2013
48
25

The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice.
Elizabeth A Thomas, Giovanni Coppola, Paula A Desplats, Bin Tang, Elisabetta Soragni, Ryan Burnett, Fuying Gao, Kelsey M Fitzgerald, Jenna F Borok, David Herman,[...]. Proc Natl Acad Sci U S A 2008
211
12

Altered chromatin architecture underlies progressive impairment of the heat shock response in mouse models of Huntington disease.
John Labbadia, Helen Cunliffe, Andreas Weiss, Elena Katsyuba, Kirupa Sathasivam, Tamara Seredenina, Ben Woodman, Saliha Moussaoui, Stefan Frentzel, Ruth Luthi-Carter,[...]. J Clin Invest 2011
128
12

Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin.
G Schilling, M W Becher, A H Sharp, H A Jinnah, K Duan, J A Kotzuk, H H Slunt, T Ratovitski, J K Cooper, N A Jenkins,[...]. Hum Mol Genet 1999
587
12

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease.
C Zuccato, A Ciammola, D Rigamonti, B R Leavitt, D Goffredo, L Conti, M E MacDonald, R M Friedlander, V Silani, M R Hayden,[...]. Science 2001
940
12

Choosing an animal model for the study of Huntington's disease.
Mahmoud A Pouladi, A Jennifer Morton, Michael R Hayden. Nat Rev Neurosci 2013
213
12

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes.
Chiara Zuccato, Marzia Tartari, Andrea Crotti, Donato Goffredo, Marta Valenza, Luciano Conti, Tiziana Cataudella, Blair R Leavitt, Michael R Hayden, Tõnis Timmusk,[...]. Nat Genet 2003
658
11

Huntingtin modulates transcription, occupies gene promoters in vivo, and binds directly to DNA in a polyglutamine-dependent manner.
Caroline L Benn, Tingting Sun, Ghazaleh Sadri-Vakili, Karen N McFarland, Derek P DiRocco, George J Yohrling, Timothy W Clark, Bérengère Bouzou, Jang-Ho J Cha. J Neurosci 2008
135
11


Histones associated with downregulated genes are hypo-acetylated in Huntington's disease models.
Ghazaleh Sadri-Vakili, Bérengère Bouzou, Caroline L Benn, Mee-Ohk Kim, Prianka Chawla, Ryan P Overland, Kelly E Glajch, Eva Xia, Zhihua Qiu, Steven M Hersch,[...]. Hum Mol Genet 2007
158
11

Brain gene expression correlates with changes in behavior in the R6/1 mouse model of Huntington's disease.
A Hodges, G Hughes, S Brooks, L Elliston, P Holmans, S B Dunnett, L Jones. Genes Brain Behav 2008
43
25

Comprehensive behavioral and molecular characterization of a new knock-in mouse model of Huntington's disease: zQ175.
Liliana B Menalled, Andrea E Kudwa, Sam Miller, Jon Fitzpatrick, Judy Watson-Johnson, Nicole Keating, Melinda Ruiz, Richard Mushlin, William Alosio, Kristi McConnell,[...]. PLoS One 2012
237
11

Huntingtin facilitates polycomb repressive complex 2.
Ihn Sik Seong, Juliana M Woda, Ji-Joon Song, Alejandro Lloret, Priyanka D Abeyrathne, Caroline J Woo, Gillian Gregory, Jong-Min Lee, Vanessa C Wheeler, Thomas Walz,[...]. Hum Mol Genet 2010
113
11

Role of brain-derived neurotrophic factor in Huntington's disease.
Chiara Zuccato, Elena Cattaneo. Prog Neurobiol 2007
391
11

RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression.
Adam Labadorf, Andrew G Hoss, Valentina Lagomarsino, Jeanne C Latourelle, Tiffany C Hadzi, Joli Bregu, Marcy E MacDonald, James F Gusella, Jiang-Fan Chen, Schahram Akbarian,[...]. PLoS One 2015
96
11

Neuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice.
Mayada Achour, Stéphanie Le Gras, Céline Keime, Frédéric Parmentier, François-Xavier Lejeune, Anne-Laurence Boutillier, Christian Néri, Irwin Davidson, Karine Merienne. Hum Mol Genet 2015
52
21

Extensive changes in DNA methylation are associated with expression of mutant huntingtin.
Christopher W Ng, Ferah Yildirim, Yoon Sing Yap, Simona Dalin, Bryan J Matthews, Patricio J Velez, Adam Labadorf, David E Housman, Ernest Fraenkel. Proc Natl Acad Sci U S A 2013
100
10

Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration.
Andrew D Strand, Zachary C Baquet, Aaron K Aragaki, Peter Holmans, Lichuan Yang, Carine Cleren, M Flint Beal, Lesley Jones, Charles Kooperberg, James M Olson,[...]. J Neurosci 2007
163
10

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila.
J S Steffan, L Bodai, J Pallos, M Poelman, A McCampbell, B L Apostol, A Kazantsev, E Schmidt, Y Z Zhu, M Greenwald,[...]. Nature 2001
909
10


Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study: analysis of 36-month observational data.
Sarah J Tabrizi, Rachael I Scahill, Gail Owen, Alexandra Durr, Blair R Leavitt, Raymund A Roos, Beth Borowsky, Bernhard Landwehrmeyer, Chris Frost, Hans Johnson,[...]. Lancet Neurol 2013
505
10

A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease.
Maria Björkqvist, Edward J Wild, Jenny Thiele, Aurelio Silvestroni, Ralph Andre, Nayana Lahiri, Elsa Raibon, Richard V Lee, Caroline L Benn, Denis Soulet,[...]. J Exp Med 2008
391
10


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.