A citation-based method for searching scientific literature

Olof Rådmark, Oliver Werz, Dieter Steinhilber, Bengt Samuelsson. Trends Biochem Sci 2007
Times Cited: 328







List of co-cited articles
899 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Leukotrienes.
Marc Peters-Golden, William R Henderson. N Engl J Med 2007
769
20


The structure of human 5-lipoxygenase.
Nathaniel C Gilbert, Sue G Bartlett, Maria T Waight, David B Neau, William E Boeglin, Alan R Brash, Marcia E Newcomer. Science 2011
275
17

5-Lipoxygenase, a key enzyme for leukotriene biosynthesis in health and disease.
Olof Rådmark, Oliver Werz, Dieter Steinhilber, Bengt Samuelsson. Biochim Biophys Acta 2015
276
15

Recent advances in the search for novel 5-lipoxygenase inhibitors.
Dieter Steinhilber, Bettina Hofmann. Basic Clin Pharmacol Toxicol 2014
79
12

5-Lipoxygenase inhibitors: a review of recent developments and patents.
Carlo Pergola, Oliver Werz. Expert Opin Ther Pat 2010
119
10



5-Lipoxygenase: mechanisms of regulation.
Olof Rådmark, Bengt Samuelsson. J Lipid Res 2009
97
9

Mammalian lipoxygenases and their biological relevance.
Hartmut Kuhn, Swathi Banthiya, Klaus van Leyen. Biochim Biophys Acta 2015
311
9


5-Lipoxygenase is a candidate target for therapeutic management of stem cell-like cells in acute myeloid leukemia.
Jessica Roos, Claudia Oancea, Maria Heinssmann, Dilawar Khan, Hannelore Held, Astrid S Kahnt, Ricardo Capelo, Estel la Buscató, Ewgenij Proschak, Elena Puccetti,[...]. Cancer Res 2014
36
22

Recent advances in the search for novel 5-lipoxygenase inhibitors for the treatment of asthma.
Ferdinando Bruno, Giuseppe Spaziano, Angela Liparulo, Fiorentina Roviezzo, Seyed Mohammed Nabavi, Antoni Sureda, Rosanna Filosa, Bruno D'Agostino. Eur J Med Chem 2018
37
21

Loss of the Alox5 gene impairs leukemia stem cells and prevents chronic myeloid leukemia.
Yaoyu Chen, Yiguo Hu, Haojian Zhang, Cong Peng, Shaoguang Li. Nat Genet 2009
224
7



Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity.
Oliver Werz, Jana Gerstmeier, Stephania Libreros, Xavier De la Rosa, Markus Werner, Paul C Norris, Nan Chiang, Charles N Serhan. Nat Commun 2018
134
7


Therapeutic options for 5-lipoxygenase inhibitors.
Oliver Werz, Dieter Steinhilber. Pharmacol Ther 2006
181
6

Molecular enzymology of lipoxygenases.
Igor Ivanov, Dagmar Heydeck, Katharina Hofheinz, Jana Roffeis, Valerie B O'Donnell, Hartmut Kuhn, Matthias Walther. Arch Biochem Biophys 2010
174
6

Arachidonic acid promotes phosphorylation of 5-lipoxygenase at Ser-271 by MAPK-activated protein kinase 2 (MK2).
Oliver Werz, Dagmar Szellas, Dieter Steinhilber, Olof Rådmark. J Biol Chem 2002
96
6

Crystal structure of inhibitor-bound human 5-lipoxygenase-activating protein.
Andrew D Ferguson, Brian M McKeever, Shihua Xu, Douglas Wisniewski, Douglas K Miller, Ting-Ting Yamin, Robert H Spencer, Lin Chu, Feroze Ujjainwalla, Barry R Cunningham,[...]. Science 2007
170
6

5-lipoxygenase: cellular biology and molecular pharmacology.
Oliver Werz. Curr Drug Targets Inflamm Allergy 2002
131
6

Phosphorylation of serine 271 on 5-lipoxygenase and its role in nuclear export.
Nicolas Flamand, Ming Luo, Marc Peters-Golden, Thomas G Brock. J Biol Chem 2009
41
14

Phosphorylation- and stimulus-dependent inhibition of cellular 5-lipoxygenase activity by nonredox-type inhibitors.
Lutz Fischer, Dagmar Szellas, Olof Rådmark, Dieter Steinhilber, Oliver Werz. FASEB J 2003
112
6

5-lipoxygenase inhibitory activity of zileuton.
G W Carter, P R Young, D H Albert, J Bouska, R Dyer, R L Bell, J B Summers, D W Brooks. J Pharmacol Exp Ther 1991
383
6

A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis.
T Yokomizo, T Izumi, K Chang, Y Takuwa, T Shimizu. Nature 1997
786
6

Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation.
Makoto Arita, Taisuke Ohira, Yee-Ping Sun, Siva Elangovan, Nan Chiang, Charles N Serhan. J Immunol 2007
418
6

5-Lipoxygenase.
A W Ford-Hutchinson, M Gresser, R N Young. Annu Rev Biochem 1994
362
6

Ferroptosis: an iron-dependent form of nonapoptotic cell death.
Scott J Dixon, Kathryn M Lemberg, Michael R Lamprecht, Rachid Skouta, Eleina M Zaitsev, Caroline E Gleason, Darpan N Patel, Andras J Bauer, Alexandra M Cantley, Wan Seok Yang,[...]. Cell 2012
6

Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis.
Wan Seok Yang, Katherine J Kim, Michael M Gaschler, Milesh Patel, Mikhail S Shchepinov, Brent R Stockwell. Proc Natl Acad Sci U S A 2016
638
6

5-Lipoxygenase inhibitors: a review of recent patents (2010-2012).
Bettina Hofmann, Dieter Steinhilber. Expert Opin Ther Pat 2013
28
21

Increased 5-lipoxygenase immunoreactivity in the hippocampus of patients with Alzheimer's disease.
Milos D Ikonomovic, Eric E Abrahamson, Tolga Uz, Hari Manev, Steven T Dekosky. J Histochem Cytochem 2008
101
6

Leukotrienes: underappreciated mediators of innate immune responses.
Marc Peters-Golden, Claudio Canetti, Peter Mancuso, Michael J Coffey. J Immunol 2005
207
6

Resolvins and protectins in inflammation resolution.
Charles N Serhan, Nicos A Petasis. Chem Rev 2011
604
6

The structural basis for specificity in lipoxygenase catalysis.
Marcia E Newcomer, Alan R Brash. Protein Sci 2015
116
6

Nuclear localization of 5-lipoxygenase as a determinant of leukotriene B4 synthetic capacity.
Ming Luo, Sandra M Jones, Marc Peters-Golden, Thomas G Brock. Proc Natl Acad Sci U S A 2003
107
6

Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene.
X S Chen, J R Sheller, E N Johnson, C D Funk. Nature 1994
326
5

Time-resolved in situ assembly of the leukotriene-synthetic 5-lipoxygenase/5-lipoxygenase-activating protein complex in blood leukocytes.
Jana Gerstmeier, Christina Weinigel, Silke Rummler, Olof Rådmark, Oliver Werz, Ulrike Garscha. FASEB J 2016
43
11

What's all the FLAP about?: 5-lipoxygenase-activating protein inhibitors for inflammatory diseases.
Jilly F Evans, Andrew D Ferguson, Ralph T Mosley, John H Hutchinson. Trends Pharmacol Sci 2008
171
5

5-lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases.
O Werz, J Klemm, B Samuelsson, O Rådmark. Proc Natl Acad Sci U S A 2000
178
5

Extracellular signal-regulated kinases phosphorylate 5-lipoxygenase and stimulate 5-lipoxygenase product formation in leukocytes.
Oliver Werz, Eva Bürkert, Lutz Fischer, Dagmar Szellas, David Dishart, Bengt Samuelsson, Olof Rådmark, Dieter Steinhilber. FASEB J 2002
109
5

Protein kinase A inhibits leukotriene synthesis by phosphorylation of 5-lipoxygenase on serine 523.
Ming Luo, Sandra M Jones, Susan M Phare, Michael J Coffey, Marc Peters-Golden, Thomas G Brock. J Biol Chem 2004
89
5

Neutrophil-derived leukotriene B4 is required for inflammatory arthritis.
Mei Chen, Bing K Lam, Yoshihide Kanaoka, Peter A Nigrovic, Laurent P Audoly, K Frank Austen, David M Lee. J Exp Med 2006
216
5

Resolvin E1 and protectin D1 activate inflammation-resolution programmes.
Jan M Schwab, Nan Chiang, Makoto Arita, Charles N Serhan. Nature 2007
833
5


Regulation of tumorigenic Wnt signaling by cyclooxygenase-2, 5-lipoxygenase and their pharmacological inhibitors: A basis for novel drugs targeting cancer cells?
Jessica Roos, Sabine Grösch, Oliver Werz, Peter Schröder, Slava Ziegler, Simone Fulda, Patrick Paulus, Anja Urbschat, Benjamin Kühn, Isabelle Maucher,[...]. Pharmacol Ther 2016
23
21

5-lipoxygenase: underappreciated role of a pro-inflammatory enzyme in tumorigenesis.
Dieter Steinhilber, Astrid Stefanie Fischer, Julia Metzner, Svenja Dorothea Steinbrink, Jessica Roos, Martin Ruthardt, Thorsten Jürgen Maier. Front Pharmacol 2010
41
12

Proresolving lipid mediators and mechanisms in the resolution of acute inflammation.
Christopher D Buckley, Derek W Gilroy, Charles N Serhan. Immunity 2014
505
5

Infection regulates pro-resolving mediators that lower antibiotic requirements.
Nan Chiang, Gabrielle Fredman, Fredrik Bäckhed, Sungwhan F Oh, Thad Vickery, Birgitta A Schmidt, Charles N Serhan. Nature 2012
434
5


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.