A citation-based method for searching scientific literature

Rajat Rohatgi, Ljiljana Milenkovic, Matthew P Scott. Science 2007
Times Cited: 954







List of co-cited articles
1384 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Vertebrate Smoothened functions at the primary cilium.
Kevin C Corbit, Pia Aanstad, Veena Singla, Andrew R Norman, Didier Y R Stainier, Jeremy F Reiter. Nature 2005
48

Hedgehog signalling in the mouse requires intraflagellar transport proteins.
Danwei Huangfu, Aimin Liu, Andrew S Rakeman, Noel S Murcia, Lee Niswander, Kathryn V Anderson. Nature 2003
966
31

Genes and molecular pathways underpinning ciliopathies.
Jeremy F Reiter, Michel R Leroux. Nat Rev Mol Cell Biol 2017
497
24

Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function.
Courtney J Haycraft, Boglarka Banizs, Yesim Aydin-Son, Qihong Zhang, Edward J Michaud, Bradley K Yoder. PLoS Genet 2005
644
21

The mechanisms of Hedgehog signalling and its roles in development and disease.
James Briscoe, Pascal P Thérond. Nat Rev Mol Cell Biol 2013
979
19

The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling.
Saikat Mukhopadhyay, Xiaohui Wen, Navneet Ratti, Alexander Loktev, Linda Rangell, Suzie J Scales, Peter K Jackson. Cell 2013
266
19

The primary cilium: a signalling centre during vertebrate development.
Sarah C Goetz, Kathryn V Anderson. Nat Rev Genet 2010
19

Cellular signalling by primary cilia in development, organ function and disease.
Zeinab Anvarian, Kirk Mykytyn, Saikat Mukhopadhyay, Lotte Bang Pedersen, Søren Tvorup Christensen. Nat Rev Nephrol 2019
170
17

Dual and opposing roles of primary cilia in medulloblastoma development.
Young-Goo Han, Hong Joo Kim, Andrzej A Dlugosz, David W Ellison, Richard J Gilbertson, Arturo Alvarez-Buylla. Nat Med 2009
269
14

HEF1-dependent Aurora A activation induces disassembly of the primary cilium.
Elena N Pugacheva, Sandra A Jablonski, Tiffiney R Hartman, Elizabeth P Henske, Erica A Golemis. Cell 2007
573
14

Biochemical mechanisms of vertebrate hedgehog signaling.
Jennifer H Kong, Christian Siebold, Rajat Rohatgi. Development 2019
83
16

Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling.
Francesc R Garcia-Gonzalo, Siew C Phua, Elle C Roberson, Galo Garcia, Monika Abedin, Stéphane Schurmans, Takanari Inoue, Jeremy F Reiter. Dev Cell 2015
172
13

Primary Cilia and Mammalian Hedgehog Signaling.
Fiona Bangs, Kathryn V Anderson. Cold Spring Harb Perspect Biol 2017
242
13


Signaling through the Primary Cilium.
Gabrielle Wheway, Liliya Nazlamova, John T Hancock. Front Cell Dev Biol 2018
148
12


Proteomics of Primary Cilia by Proximity Labeling.
David U Mick, Rachel B Rodrigues, Ryan D Leib, Christopher M Adams, Allis S Chien, Steven P Gygi, Maxence V Nachury. Dev Cell 2015
199
12

Modulation of Ciliary Phosphoinositide Content Regulates Trafficking and Sonic Hedgehog Signaling Output.
Marcelo Chávez, Sabrina Ena, Jacqueline Van Sande, Alban de Kerchove d'Exaerde, Stéphane Schurmans, Serge N Schiffmann. Dev Cell 2015
153
12

Cilia and Hedgehog responsiveness in the mouse.
Danwei Huangfu, Kathryn V Anderson. Proc Natl Acad Sci U S A 2005
597
12

Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis.
Sunny Y Wong, Allen D Seol, Po-Lin So, Alexandre N Ermilov, Christopher K Bichakjian, Ervin H Epstein, Andrzej A Dlugosz, Jeremy F Reiter. Nat Med 2009
315
11

IFT27 links the BBSome to IFT for maintenance of the ciliary signaling compartment.
Thibaut Eguether, Jovenal T San Agustin, Brian T Keady, Julie A Jonassen, Yinwen Liang, Richard Francis, Kimimasa Tobita, Colin A Johnson, Zakia A Abdelhamed, Cecilia W Lo,[...]. Dev Cell 2014
147
11

Structural basis of Smoothened regulation by its extracellular domains.
Eamon F X Byrne, Ria Sircar, Paul S Miller, George Hedger, Giovanni Luchetti, Sigrid Nachtergaele, Mark D Tully, Laurel Mydock-McGrane, Douglas F Covey, Robert P Rambo,[...]. Nature 2016
199
11

Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling.
Pengxiang Huang, Daniel Nedelcu, Miyako Watanabe, Cindy Jao, Youngchang Kim, Jing Liu, Adrian Salic. Cell 2016
192
11

The graded response to Sonic Hedgehog depends on cilia architecture.
Tamara Caspary, Christine E Larkins, Kathryn V Anderson. Dev Cell 2007
491
11


Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling.
Pawel Niewiadomski, Jennifer H Kong, Robert Ahrends, Yan Ma, Eric W Humke, Sohini Khan, Mary N Teruel, Bennett G Novitch, Rajat Rohatgi. Cell Rep 2014
138
11

Establishing and regulating the composition of cilia for signal transduction.
Maxence V Nachury, David U Mick. Nat Rev Mol Cell Biol 2019
114
11

TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia.
Saikat Mukhopadhyay, Xiaohui Wen, Ben Chih, Christopher D Nelson, William S Lane, Suzie J Scales, Peter K Jackson. Genes Dev 2010
223
10

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells.
Surya M Nauli, Francis J Alenghat, Ying Luo, Eric Williams, Peter Vassilev, Xiaogang Li, Andrew E H Elia, Weining Lu, Edward M Brown, Stephen J Quinn,[...]. Nat Genet 2003
10

The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins.
Eric W Humke, Karolin V Dorn, Ljiljana Milenkovic, Matthew P Scott, Rajat Rohatgi. Genes Dev 2010
304
10

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function.
C Chiang, Y Litingtung, E Lee, K E Young, J L Corden, H Westphal, P A Beachy. Nature 1996
10

Smoothened stimulation by membrane sterols drives Hedgehog pathway activity.
Ishan Deshpande, Jiahao Liang, Danielle Hedeen, Kelsey J Roberts, Yunxiao Zhang, Betty Ha, Naomi R Latorraca, Bryan Faust, Ron O Dror, Philip A Beachy,[...]. Nature 2019
67
14

Smoothened determines β-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium.
Kasturi Pal, Sun-Hee Hwang, Bandarigoda Somatilaka, Hemant Badgandi, Peter K Jackson, Kathryn DeFea, Saikat Mukhopadhyay. J Cell Biol 2016
75
13

Altered neural cell fates and medulloblastoma in mouse patched mutants.
L V Goodrich, L Milenković, K M Higgins, M P Scott. Science 1997
10

IFT25 links the signal-dependent movement of Hedgehog components to intraflagellar transport.
Brian T Keady, Rajeev Samtani, Kimimasa Tobita, Maiko Tsuchya, Jovenal T San Agustin, John A Follit, Julie A Jonassen, Ramiah Subramanian, Cecilia W Lo, Gregory J Pazour. Dev Cell 2012
141
9

A motility in the eukaryotic flagellum unrelated to flagellar beating.
K G Kozminski, K A Johnson, P Forscher, J L Rosenbaum. Proc Natl Acad Sci U S A 1993
661
9


Intraflagellar transport.
Joel L Rosenbaum, George B Witman. Nat Rev Mol Cell Biol 2002
9

Hedgehog pathway modulation by multiple lipid binding sites on the smoothened effector of signal response.
Benjamin R Myers, Navdar Sever, Yong Chun Chong, James Kim, Jitendra D Belani, Scott Rychnovsky, J Fernando Bazan, Philip A Beachy. Dev Cell 2013
123
9

Sonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothened.
Yongbin Chen, Noriaki Sasai, Guoqiang Ma, Tao Yue, Jianhang Jia, James Briscoe, Jin Jiang. PLoS Biol 2011
139
9

Activating Smoothened mutations in sporadic basal-cell carcinoma.
J Xie, M Murone, S M Luoh, A Ryan, Q Gu, C Zhang, J M Bonifas, C W Lam, M Hynes, A Goddard,[...]. Nature 1998
986
9

Rapid, direct activity assays for Smoothened reveal Hedgehog pathway regulation by membrane cholesterol and extracellular sodium.
Benjamin R Myers, Lila Neahring, Yunxiao Zhang, Kelsey J Roberts, Philip A Beachy. Proc Natl Acad Sci U S A 2017
65
13

Mutations affecting segment number and polarity in Drosophila.
C Nüsslein-Volhard, E Wieschaus. Nature 1980
9

CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog.
Ganesh V Pusapati, Jennifer H Kong, Bhaven B Patel, Arunkumar Krishnan, Andreas Sagner, Maia Kinnebrew, James Briscoe, L Aravind, Rajat Rohatgi. Dev Cell 2018
51
17

Cholesterol accessibility at the ciliary membrane controls hedgehog signaling.
Maia Kinnebrew, Ellen J Iverson, Bhaven B Patel, Ganesh V Pusapati, Jennifer H Kong, Kristen A Johnson, Giovanni Luchetti, Kaitlyn M Eckert, Jeffrey G McDonald, Douglas F Covey,[...]. Elife 2019
41
21

Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision.
Siew Cheng Phua, Shuhei Chiba, Masako Suzuki, Emily Su, Elle C Roberson, Ganesh V Pusapati, Stéphane Schurmans, Mitsutoshi Setou, Rajat Rohatgi, Jeremy F Reiter,[...]. Cell 2017
154
9

Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins.
Hemant B Badgandi, Sun-Hee Hwang, Issei S Shimada, Evan Loriot, Saikat Mukhopadhyay. J Cell Biol 2017
76
10


Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease.
Gregory J Pazour, Jovenal T San Agustin, John A Follit, Joel L Rosenbaum, George B Witman. Curr Biol 2002
380
8



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.