Cecile Morlot, Nicole M Thielens, Raimond B G Ravelli, Wieger Hemrika, Roland A Romijn, Piet Gros, Stephen Cusack, Andrew A McCarthy. Proc Natl Acad Sci U S A 2007
Times Cited: 129
Times Cited: 129
Times Cited
Times Co-cited
Similarity
Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance.
K Brose, K S Bland, K H Wang, D Arnott, W Henzel, C S Goodman, M Tessier-Lavigne, T Kidd. Cell 1999
K Brose, K S Bland, K H Wang, D Arnott, W Henzel, C S Goodman, M Tessier-Lavigne, T Kidd. Cell 1999
48
Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors.
T Kidd, K Brose, K J Mitchell, R D Fetter, M Tessier-Lavigne, C S Goodman, G Tear. Cell 1998
T Kidd, K Brose, K J Mitchell, R D Fetter, M Tessier-Lavigne, C S Goodman, G Tear. Cell 1998
35
Magic roundabout is a new member of the roundabout receptor family that is endothelial specific and expressed at sites of active angiogenesis.
Lukasz Huminiecki, Michael Gorn, Steven Suchting, Richard Poulsom, Roy Bicknell. Genomics 2002
Lukasz Huminiecki, Michael Gorn, Steven Suchting, Richard Poulsom, Roy Bicknell. Genomics 2002
34
Slit is the midline repellent for the robo receptor in Drosophila.
T Kidd, K S Bland, C S Goodman. Cell 1999
T Kidd, K S Bland, C S Goodman. Cell 1999
29
Structural and functional analysis of slit and heparin binding to immunoglobulin-like domains 1 and 2 of Drosophila Robo.
Noémi Fukuhara, Jason A Howitt, Sadaf-Ahmahni Hussain, Erhard Hohenester. J Biol Chem 2008
Noémi Fukuhara, Jason A Howitt, Sadaf-Ahmahni Hussain, Erhard Hohenester. J Biol Chem 2008
45
Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability.
Christopher A Jones, Nyall R London, Haoyu Chen, Kye Won Park, Dominique Sauvaget, Rebecca A Stockton, Joshua D Wythe, Wonhee Suh, Frederic Larrieu-Lahargue, Yoh-Suke Mukouyama,[...]. Nat Med 2008
Christopher A Jones, Nyall R London, Haoyu Chen, Kye Won Park, Dominique Sauvaget, Rebecca A Stockton, Joshua D Wythe, Wonhee Suh, Frederic Larrieu-Lahargue, Yoh-Suke Mukouyama,[...]. Nat Med 2008
28
Binding site for Robo receptors revealed by dissection of the leucine-rich repeat region of Slit.
Jason A Howitt, Naomi J Clout, Erhard Hohenester. EMBO J 2004
Jason A Howitt, Naomi J Clout, Erhard Hohenester. EMBO J 2004
28
Regulation of commissural axon pathfinding by slit and its Robo receptors.
Barry J Dickson, Giorgio F Gilestro. Annu Rev Cell Dev Biol 2006
Barry J Dickson, Giorgio F Gilestro. Annu Rev Cell Dev Biol 2006
27
Robo4 is a vascular-specific receptor that inhibits endothelial migration.
Kye Won Park, Clayton M Morrison, Lise K Sorensen, Christopher A Jones, Yi Rao, Chi-Bin Chien, Jane Y Wu, Lisa D Urness, Dean Y Li. Dev Biol 2003
Kye Won Park, Clayton M Morrison, Lise K Sorensen, Christopher A Jones, Yi Rao, Chi-Bin Chien, Jane Y Wu, Lisa D Urness, Dean Y Li. Dev Biol 2003
27
Signaling switch of the axon guidance receptor Robo3 during vertebrate evolution.
Pavol Zelina, Heike Blockus, Yvrick Zagar, Amélie Péres, François Friocourt, Zhuhao Wu, Nicolas Rama, Coralie Fouquet, Erhard Hohenester, Marc Tessier-Lavigne,[...]. Neuron 2014
Pavol Zelina, Heike Blockus, Yvrick Zagar, Amélie Péres, François Friocourt, Zhuhao Wu, Nicolas Rama, Coralie Fouquet, Erhard Hohenester, Marc Tessier-Lavigne,[...]. Neuron 2014
26
Extracellular Ig domains 1 and 2 of Robo are important for ligand (Slit) binding.
Zhe Liu, Kalpana Patel, Hannes Schmidt, William Andrews, Adrian Pini, Vasi Sundaresan. Mol Cell Neurosci 2004
Zhe Liu, Kalpana Patel, Hannes Schmidt, William Andrews, Adrian Pini, Vasi Sundaresan. Mol Cell Neurosci 2004
30
Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity.
Biao Wang, Yang Xiao, Bei Bei Ding, Na Zhang, Xiao bin Yuan, Lü Gui, Kai Xian Qian, Shumin Duan, Zhengjun Chen, Yi Rao,[...]. Cancer Cell 2003
Biao Wang, Yang Xiao, Bei Bei Ding, Na Zhang, Xiao bin Yuan, Lü Gui, Kai Xian Qian, Shumin Duan, Zhengjun Chen, Yi Rao,[...]. Cancer Cell 2003
23
Active involvement of Robo1 and Robo4 in filopodia formation and endothelial cell motility mediated via WASP and other actin nucleation-promoting factors.
Helen Sheldon, Maud Andre, John A Legg, Paul Heal, John M Herbert, Richard Sainson, Anshula S Sharma, Jan K Kitajewski, Victoria L Heath, Roy Bicknell. FASEB J 2009
Helen Sheldon, Maud Andre, John A Legg, Paul Heal, John M Herbert, Richard Sainson, Anshula S Sharma, Jan K Kitajewski, Victoria L Heath, Roy Bicknell. FASEB J 2009
24
Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity.
Christopher A Jones, Naoyuki Nishiya, Nyall R London, Weiquan Zhu, Lise K Sorensen, Aubrey C Chan, Chinten J Lim, Haoyu Chen, Qisheng Zhang, Peter G Schultz,[...]. Nat Cell Biol 2009
Christopher A Jones, Naoyuki Nishiya, Nyall R London, Weiquan Zhu, Lise K Sorensen, Aubrey C Chan, Chinten J Lim, Haoyu Chen, Qisheng Zhang, Peter G Schultz,[...]. Nat Cell Biol 2009
23
Robo4 maintains vessel integrity and inhibits angiogenesis by interacting with UNC5B.
Alexander W Koch, Thomas Mathivet, Bruno Larrivée, Raymond K Tong, Joe Kowalski, Laurence Pibouin-Fragner, Karine Bouvrée, Scott Stawicki, Katrina Nicholes, Nisha Rathore,[...]. Dev Cell 2011
Alexander W Koch, Thomas Mathivet, Bruno Larrivée, Raymond K Tong, Joe Kowalski, Laurence Pibouin-Fragner, Karine Bouvrée, Scott Stawicki, Katrina Nicholes, Nisha Rathore,[...]. Dev Cell 2011
23
Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.
K Wong, X R Ren, Y Z Huang, Y Xie, G Liu, H Saito, H Tang, L Wen, S M Brady-Kalnay, L Mei,[...]. Cell 2001
K Wong, X R Ren, Y Z Huang, Y Xie, G Liu, H Saito, H Tang, L Wen, S M Brady-Kalnay, L Mei,[...]. Cell 2001
23
The neuronal repellent Slit inhibits leukocyte chemotaxis induced by chemotactic factors.
J Y Wu, L Feng, H T Park, N Havlioglu, L Wen, H Tang, K B Bacon, Jiang Zh, Zhang Xc, Y Rao. Nature 2001
J Y Wu, L Feng, H T Park, N Havlioglu, L Wen, H Tang, K B Bacon, Jiang Zh, Zhang Xc, Y Rao. Nature 2001
22
Soluble Robo4 receptor inhibits in vivo angiogenesis and endothelial cell migration.
Steven Suchting, Paul Heal, Kiki Tahtis, Lorna M Stewart, Roy Bicknell. FASEB J 2005
Steven Suchting, Paul Heal, Kiki Tahtis, Lorna M Stewart, Roy Bicknell. FASEB J 2005
20
A molecular mechanism for the heparan sulfate dependence of slit-robo signaling.
Sadaf-Ahmahni Hussain, Michael Piper, Noémi Fukuhara, Laure Strochlic, Gian Cho, Jason A Howitt, Yassir Ahmed, Andrew K Powell, Jeremy E Turnbull, Christine E Holt,[...]. J Biol Chem 2006
Sadaf-Ahmahni Hussain, Michael Piper, Noémi Fukuhara, Laure Strochlic, Gian Cho, Jason A Howitt, Yassir Ahmed, Andrew K Powell, Jeremy E Turnbull, Christine E Holt,[...]. J Biol Chem 2006
20
Repulsive axon guidance molecule Slit3 is a novel angiogenic factor.
Bing Zhang, Ursula M Dietrich, Jian-Guo Geng, Roy Bicknell, Jeffrey D Esko, Lianchun Wang. Blood 2009
Bing Zhang, Ursula M Dietrich, Jian-Guo Geng, Roy Bicknell, Jeffrey D Esko, Lianchun Wang. Blood 2009
18
The Adam family metalloprotease Kuzbanian regulates the cleavage of the roundabout receptor to control axon repulsion at the midline.
Hope A Coleman, Juan-Pablo Labrador, Rebecca K Chance, Greg J Bashaw. Development 2010
Hope A Coleman, Juan-Pablo Labrador, Rebecca K Chance, Greg J Bashaw. Development 2010
26
Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor.
G J Bashaw, T Kidd, D Murray, T Pawson, C S Goodman. Cell 2000
G J Bashaw, T Kidd, D Murray, T Pawson, C S Goodman. Cell 2000
18
Robo2 acts in trans to inhibit Slit-Robo1 repulsion in pre-crossing commissural axons.
Timothy A Evans, Celine Santiago, Elise Arbeille, Greg J Bashaw. Elife 2015
Timothy A Evans, Celine Santiago, Elise Arbeille, Greg J Bashaw. Elife 2015
38
Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization.
Nicolas Rama, Alexandre Dubrac, Thomas Mathivet, Róisín-Ana Ní Chárthaigh, Gael Genet, Brunella Cristofaro, Laurence Pibouin-Fragner, Le Ma, Anne Eichmann, Alain Chédotal. Nat Med 2015
Nicolas Rama, Alexandre Dubrac, Thomas Mathivet, Róisín-Ana Ní Chárthaigh, Gael Genet, Brunella Cristofaro, Laurence Pibouin-Fragner, Le Ma, Anne Eichmann, Alain Chédotal. Nat Med 2015
17
Conserved roles for Slit and Robo proteins in midline commissural axon guidance.
Hua Long, Christelle Sabatier, Le Ma, Andrew Plump, Wenlin Yuan, David M Ornitz, Atsushi Tamada, Fujio Murakami, Corey S Goodman, Marc Tessier-Lavigne. Neuron 2004
Hua Long, Christelle Sabatier, Le Ma, Andrew Plump, Wenlin Yuan, David M Ornitz, Atsushi Tamada, Fujio Murakami, Corey S Goodman, Marc Tessier-Lavigne. Neuron 2004
16
Mutations affecting growth cone guidance in Drosophila: genes necessary for guidance toward or away from the midline.
M Seeger, G Tear, D Ferres-Marco, C S Goodman. Neuron 1993
M Seeger, G Tear, D Ferres-Marco, C S Goodman. Neuron 1993
16
PlexinA1 is a new Slit receptor and mediates axon guidance function of Slit C-terminal fragments.
Céline Delloye-Bourgeois, Arnaud Jacquier, Camille Charoy, Florie Reynaud, Homaira Nawabi, Karine Thoinet, Karine Kindbeiter, Yutaka Yoshida, Yvrick Zagar, Youxin Kong,[...]. Nat Neurosci 2015
Céline Delloye-Bourgeois, Arnaud Jacquier, Camille Charoy, Florie Reynaud, Homaira Nawabi, Karine Thoinet, Karine Kindbeiter, Yutaka Yoshida, Yvrick Zagar, Youxin Kong,[...]. Nat Neurosci 2015
25
roundabout4 is essential for angiogenesis in vivo.
Victoria M Bedell, Sang-Yeob Yeo, Kye Won Park, Jeffrey Chung, Pankaj Seth, Venkatesha Shivalingappa, Jinhua Zhao, Tomoko Obara, Vikas P Sukhatme, Iain A Drummond,[...]. Proc Natl Acad Sci U S A 2005
Victoria M Bedell, Sang-Yeob Yeo, Kye Won Park, Jeffrey Chung, Pankaj Seth, Venkatesha Shivalingappa, Jinhua Zhao, Tomoko Obara, Vikas P Sukhatme, Iain A Drummond,[...]. Proc Natl Acad Sci U S A 2005
15
Targeting Robo4-dependent Slit signaling to survive the cytokine storm in sepsis and influenza.
Nyall R London, Weiquan Zhu, Fernando A Bozza, Matthew C P Smith, Daniel M Greif, Lise K Sorensen, Luming Chen, Yuuki Kaminoh, Aubrey C Chan, Samuel F Passi,[...]. Sci Transl Med 2010
Nyall R London, Weiquan Zhu, Fernando A Bozza, Matthew C P Smith, Daniel M Greif, Lise K Sorensen, Luming Chen, Yuuki Kaminoh, Aubrey C Chan, Samuel F Passi,[...]. Sci Transl Med 2010
15
Vascular Robo4 restricts proangiogenic VEGF signaling in breast.
Rebecca Marlow, Mikhail Binnewies, Lise K Sorensen, Stefanie D Monica, Phyllis Strickland, E Camilla Forsberg, Dean Y Li, Lindsay Hinck. Proc Natl Acad Sci U S A 2010
Rebecca Marlow, Mikhail Binnewies, Lise K Sorensen, Stefanie D Monica, Phyllis Strickland, E Camilla Forsberg, Dean Y Li, Lindsay Hinck. Proc Natl Acad Sci U S A 2010
23
Moving away from the midline: new developments for Slit and Robo.
Athena R Ypsilanti, Yvrick Zagar, Alain Chédotal. Development 2010
Athena R Ypsilanti, Yvrick Zagar, Alain Chédotal. Development 2010
15
Biochemical purification of a mammalian slit protein as a positive regulator of sensory axon elongation and branching.
K H Wang, K Brose, D Arnott, T Kidd, C S Goodman, W Henzel, M Tessier-Lavigne. Cell 1999
K H Wang, K Brose, D Arnott, T Kidd, C S Goodman, W Henzel, M Tessier-Lavigne. Cell 1999
15
Functional diversity of Robo receptor immunoglobulin domains promotes distinct axon guidance decisions.
Timothy A Evans, Greg J Bashaw. Curr Biol 2010
Timothy A Evans, Greg J Bashaw. Curr Biol 2010
32
Structure and functional relevance of the Slit2 homodimerization domain.
Elena Seiradake, Anne C von Philipsborn, Maud Henry, Martin Fritz, Hugues Lortat-Jacob, Marc Jamin, Wieger Hemrika, Martin Bastmeyer, Stephen Cusack, Andrew A McCarthy. EMBO Rep 2009
Elena Seiradake, Anne C von Philipsborn, Maud Henry, Martin Fritz, Hugues Lortat-Jacob, Marc Jamin, Wieger Hemrika, Martin Bastmeyer, Stephen Cusack, Andrew A McCarthy. EMBO Rep 2009
48
Diversity and specificity of actions of Slit2 proteolytic fragments in axon guidance.
K T Nguyen Ba-Charvet, K Brose, L Ma, K H Wang, V Marillat, C Sotelo, M Tessier-Lavigne, A Chédotal. J Neurosci 2001
K T Nguyen Ba-Charvet, K Brose, L Ma, K H Wang, V Marillat, C Sotelo, M Tessier-Lavigne, A Chédotal. J Neurosci 2001
14
Human ROBO1 is cleaved by metalloproteinases and gamma-secretase and migrates to the nucleus in cancer cells.
Motoaki Seki, Akira Watanabe, Satoshi Enomoto, Takeshi Kawamura, Hirotaka Ito, Tatsuhiko Kodama, Takao Hamakubo, Hiroyuki Aburatani. FEBS Lett 2010
Motoaki Seki, Akira Watanabe, Satoshi Enomoto, Takeshi Kawamura, Hirotaka Ito, Tatsuhiko Kodama, Takao Hamakubo, Hiroyuki Aburatani. FEBS Lett 2010
31
Cell-surface heparan sulfate is involved in the repulsive guidance activities of Slit2 protein.
H Hu. Nat Neurosci 2001
H Hu. Nat Neurosci 2001
14
slit: an EGF-homologous locus of D. melanogaster involved in the development of the embryonic central nervous system.
J M Rothberg, D A Hartley, Z Walther, S Artavanis-Tsakonas. Cell 1988
J M Rothberg, D A Hartley, Z Walther, S Artavanis-Tsakonas. Cell 1988
14
Operational redundancy in axon guidance through the multifunctional receptor Robo3 and its ligand NELL2.
Alexander Jaworski, Irene Tom, Raymond K Tong, Holly K Gildea, Alexander W Koch, Lino C Gonzalez, Marc Tessier-Lavigne. Science 2015
Alexander Jaworski, Irene Tom, Raymond K Tong, Holly K Gildea, Alexander W Koch, Lino C Gonzalez, Marc Tessier-Lavigne. Science 2015
24
slit: an extracellular protein necessary for development of midline glia and commissural axon pathways contains both EGF and LRR domains.
J M Rothberg, J R Jacobs, C S Goodman, S Artavanis-Tsakonas. Genes Dev 1990
J M Rothberg, J R Jacobs, C S Goodman, S Artavanis-Tsakonas. Genes Dev 1990
13
The divergent Robo family protein rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axons.
Christelle Sabatier, Andrew S Plump, Le Ma, Katja Brose, Atsushi Tamada, Fujio Murakami, Eva Y-H P Lee, Marc Tessier-Lavigne. Cell 2004
Christelle Sabatier, Andrew S Plump, Le Ma, Katja Brose, Atsushi Tamada, Fujio Murakami, Eva Y-H P Lee, Marc Tessier-Lavigne. Cell 2004
13
Crossing the midline: roles and regulation of Robo receptors.
S Rajagopalan, E Nicolas, V Vivancos, J Berger, B J Dickson. Neuron 2000
S Rajagopalan, E Nicolas, V Vivancos, J Berger, B J Dickson. Neuron 2000
13
Heparan sulfate proteoglycan syndecan promotes axonal and myotube guidance by slit/robo signaling.
Patrick Steigemann, Andreas Molitor, Sonja Fellert, Herbert Jäckle, Gerd Vorbrüggen. Curr Biol 2004
Patrick Steigemann, Andreas Molitor, Sonja Fellert, Herbert Jäckle, Gerd Vorbrüggen. Curr Biol 2004
13
Comm sorts robo to control axon guidance at the Drosophila midline.
Krystyna Keleman, Srikanth Rajagopalan, Diana Cleppien, David Teis, Karin Paiha, Lukas A Huber, Gerhard M Technau, Barry J Dickson. Cell 2002
Krystyna Keleman, Srikanth Rajagopalan, Diana Cleppien, David Teis, Karin Paiha, Lukas A Huber, Gerhard M Technau, Barry J Dickson. Cell 2002
13
Hierarchical organization of guidance receptors: silencing of netrin attraction by slit through a Robo/DCC receptor complex.
E Stein, M Tessier-Lavigne. Science 2001
E Stein, M Tessier-Lavigne. Science 2001
12
Vertebrate slit, a secreted ligand for the transmembrane protein roundabout, is a repellent for olfactory bulb axons.
H S Li, J H Chen, W Wu, T Fagaly, L Zhou, W Yuan, S Dupuis, Z H Jiang, W Nash, C Gick,[...]. Cell 1999
H S Li, J H Chen, W Wu, T Fagaly, L Zhou, W Yuan, S Dupuis, Z H Jiang, W Nash, C Gick,[...]. Cell 1999
12
SLIT2 attenuation during lung cancer progression deregulates beta-catenin and E-cadherin and associates with poor prognosis.
Ruo-Chia Tseng, Shih-Hua Lee, Han-Shui Hsu, Ben-Han Chen, Wan-Ching Tsai, Ching Tzao, Yi-Ching Wang. Cancer Res 2010
Ruo-Chia Tseng, Shih-Hua Lee, Han-Shui Hsu, Ben-Han Chen, Wan-Ching Tsai, Ching Tzao, Yi-Ching Wang. Cancer Res 2010
12
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.