A citation-based method for searching scientific literature

Dorothee Mueller, Christian Bach, Deniz Zeisig, Maria-Paz Garcia-Cuellar, Sara Monroe, Arun Sreekumar, Rong Zhou, Alexey Nesvizhskii, Arul Chinnaiyan, Jay L Hess, Robert K Slany. Blood 2007
Times Cited: 273







List of co-cited articles
1502 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Potent inhibition of DOT1L as treatment of MLL-fusion leukemia.
Scott R Daigle, Edward J Olhava, Carly A Therkelsen, Aravind Basavapathruni, Lei Jin, P Ann Boriack-Sjodin, Christina J Allain, Christine R Klaus, Alejandra Raimondi, Margaret Porter Scott,[...]. Blood 2013
443
46

hDOT1L links histone methylation to leukemogenesis.
Yuki Okada, Qin Feng, Yihui Lin, Qi Jiang, Yaqiang Li, Vernon M Coffield, Lishan Su, Guoliang Xu, Yi Zhang. Cell 2005
571
46

MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.
Kathrin M Bernt, Nan Zhu, Amit U Sinha, Sridhar Vempati, Joerg Faber, Andrei V Krivtsov, Zhaohui Feng, Natalie Punt, Amanda Daigle, Lars Bullinger,[...]. Cancer Cell 2011
576
44

A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription.
Akihiko Yokoyama, Min Lin, Alpana Naresh, Issay Kitabayashi, Michael L Cleary. Cancer Cell 2010
245
42

Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor.
Scott R Daigle, Edward J Olhava, Carly A Therkelsen, Christina R Majer, Christopher J Sneeringer, Jeffrey Song, L Danielle Johnston, Margaret Porter Scott, Jesse J Smith, Yonghong Xiao,[...]. Cancer Cell 2011
629
36

AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia.
Chengqi Lin, Edwin R Smith, Hidehisa Takahashi, Ka Chun Lai, Skylar Martin-Brown, Laurence Florens, Michael P Washburn, Joan W Conaway, Ronald C Conaway, Ali Shilatifard. Mol Cell 2010
386
34

H3K79 methylation profiles define murine and human MLL-AF4 leukemias.
Andrei V Krivtsov, Zhaohui Feng, Madeleine E Lemieux, Joerg Faber, Sridhar Vempati, Amit U Sinha, Xiaobo Xia, Jonathan Jesneck, Adrian P Bracken, Lewis B Silverman,[...]. Cancer Cell 2008
385
33

Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom).
Man Mohan, Hans-Martin Herz, Yoh-Hei Takahashi, Chengqi Lin, Ka Chun Lai, Ying Zhang, Michael P Washburn, Laurence Florens, Ali Shilatifard. Genes Dev 2010
201
32


Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain.
Qin Feng, Hengbin Wang, Huck Hui Ng, Hediye Erdjument-Bromage, Paul Tempst, Kevin Struhl, Yi Zhang. Curr Biol 2002
550
29

Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes.
Debabrata Biswas, Thomas A Milne, Venkatesha Basrur, Jaehoon Kim, Kojo S J Elenitoba-Johnson, C David Allis, Robert G Roeder. Proc Natl Acad Sci U S A 2011
120
28

MLL translocations, histone modifications and leukaemia stem-cell development.
Andrei V Krivtsov, Scott A Armstrong. Nat Rev Cancer 2007
775
27

DOT1L, the H3K79 methyltransferase, is required for MLL-AF9-mediated leukemogenesis.
Anh Tram Nguyen, Olena Taranova, Jin He, Yi Zhang. Blood 2011
174
27

DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.
Chun-Wei Chen, Richard P Koche, Amit U Sinha, Aniruddha J Deshpande, Nan Zhu, Rowena Eng, John G Doench, Haiming Xu, Scott H Chu, Jun Qi,[...]. Nat Med 2015
133
27

Misguided transcriptional elongation causes mixed lineage leukemia.
Dorothee Mueller, María-Paz García-Cuéllar, Christian Bach, Sebastian Buhl, Emanuel Maethner, Robert K Slany. PLoS Biol 2009
145
25

DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells.
David J Steger, Martina I Lefterova, Lei Ying, Aaron J Stonestrom, Michael Schupp, David Zhuo, Adam L Vakoc, Ja-Eun Kim, Junjie Chen, Mitchell A Lazar,[...]. Mol Cell Biol 2008
310
24

MLL targets SET domain methyltransferase activity to Hox gene promoters.
Thomas A Milne, Scott D Briggs, Hugh W Brock, Mary Ellen Martin, Denise Gibbs, C David Allis, Jay L Hess. Mol Cell 2002
775
22

AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes.
Aniruddha J Deshpande, Anagha Deshpande, Amit U Sinha, Liying Chen, Jenny Chang, Ali Cihan, Maurizio Fazio, Chun-Wei Chen, Nan Zhu, Richard Koche,[...]. Cancer Cell 2014
105
21

The diverse functions of Dot1 and H3K79 methylation.
Anh Tram Nguyen, Yi Zhang. Genes Dev 2011
355
20

Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation.
Stephanie Y Jo, Eric M Granowicz, Ivan Maillard, Dafydd Thomas, Jay L Hess. Blood 2011
146
20

AF9 YEATS domain links histone acetylation to DOT1L-mediated H3K79 methylation.
Yuanyuan Li, Hong Wen, Yuanxin Xi, Kaori Tanaka, Haibo Wang, Danni Peng, Yongfeng Ren, Qihuang Jin, Sharon Y R Dent, Wei Li,[...]. Cell 2014
194
20

Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l.
Aniruddha J Deshpande, Liying Chen, Maurizio Fazio, Amit U Sinha, Kathrin M Bernt, Deepti Banka, Stuart Dias, Jenny Chang, Edward J Olhava, Scott R Daigle,[...]. Blood 2013
115
20

Degree of recruitment of DOT1L to MLL-AF9 defines level of H3K79 Di- and tri-methylation on target genes and transformation potential.
Aravinda Kuntimaddi, Nicholas J Achille, Jeremy Thorpe, Alyson A Lokken, Ritambhara Singh, Charles S Hemenway, Mazhar Adli, Nancy J Zeleznik-Le, John H Bushweller. Cell Rep 2015
64
31


The MLL recombinome of acute leukemias in 2013.
C Meyer, J Hofmann, T Burmeister, D Gröger, T S Park, M Emerenciano, M Pombo de Oliveira, A Renneville, P Villarese, E Macintyre,[...]. Leukemia 2013
297
19

Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia.
Matthew G Guenther, Lee N Lawton, Tatiana Rozovskaia, Garrett M Frampton, Stuart S Levine, Thomas L Volkert, Carlo M Croce, Tatsuya Nakamura, Eli Canaani, Richard A Young. Genes Dev 2008
197
19

The MLL recombinome of acute leukemias in 2017.
C Meyer, T Burmeister, D Gröger, G Tsaur, L Fechina, A Renneville, R Sutton, N C Venn, M Emerenciano, M S Pombo-de-Oliveira,[...]. Leukemia 2018
277
19

MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia.
Sara C Monroe, Stephanie Y Jo, Daniel S Sanders, Venkatesha Basrur, Kojo S Elenitoba-Johnson, Robert K Slany, Jay L Hess. Exp Hematol 2011
59
30

Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors.
Wenyu Yu, Emma J Chory, Amy K Wernimont, Wolfram Tempel, Alex Scopton, Alexander Federation, Jason J Marineau, Jun Qi, Dalia Barsyte-Lovejoy, Joanna Yi,[...]. Nat Commun 2012
181
18


The pathogenesis of mixed-lineage leukemia.
Andrew G Muntean, Jay L Hess. Annu Rev Pathol 2012
215
17

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia.
Mark A Dawson, Rab K Prinjha, Antje Dittmann, George Giotopoulos, Marcus Bantscheff, Wai-In Chan, Samuel C Robson, Chun-wa Chung, Carsten Hopf, Mikhail M Savitski,[...]. Nature 2011
17

Dot1p modulates silencing in yeast by methylation of the nucleosome core.
Fred van Leeuwen, Philip R Gafken, Daniel E Gottschling. Cell 2002
605
17

Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo.
Dmitry Borkin, Shihan He, Hongzhi Miao, Katarzyna Kempinska, Jonathan Pollock, Jennifer Chase, Trupta Purohit, Bhavna Malik, Ting Zhao, Jingya Wang,[...]. Cancer Cell 2015
194
17

The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis.
Akihiko Yokoyama, Tim C P Somervaille, Kevin S Smith, Orit Rozenblatt-Rosen, Matthew Meyerson, Michael L Cleary. Cell 2005
365
17

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.
Johannes Zuber, Junwei Shi, Eric Wang, Amy R Rappaport, Harald Herrmann, Edward A Sison, Daniel Magoon, Jun Qi, Katharina Blatt, Mark Wunderlich,[...]. Nature 2011
17

Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.
Andrei V Krivtsov, David Twomey, Zhaohui Feng, Matthew C Stubbs, Yingzi Wang, Joerg Faber, Jason E Levine, Jing Wang, William C Hahn, D Gary Gilliland,[...]. Nature 2006
17

Dot1a-AF9 complex mediates histone H3 Lys-79 hypermethylation and repression of ENaCalpha in an aldosterone-sensitive manner.
Wenzheng Zhang, Xuefeng Xia, Mary Rose Reisenauer, Charles S Hemenway, Bruce C Kone. J Biol Chem 2006
128
16

Histone H3 lysine 79 methyltransferase Dot1 is required for immortalization by MLL oncogenes.
Ming-Jin Chang, Hongyu Wu, Nicholas J Achille, Mary Rose Reisenauer, Chau-Wen Chou, Nancy J Zeleznik-Le, Charles S Hemenway, Wenzheng Zhang. Cancer Res 2010
121
16

MLL-ENL inhibits polycomb repressive complex 1 to achieve efficient transformation of hematopoietic cells.
Emanuel Maethner, Maria-Paz Garcia-Cuellar, Constanze Breitinger, Sylvia Takacova, Vladimir Divoky, Jay L Hess, Robert K Slany. Cell Rep 2013
37
43

Combinatorial patterns of histone acetylations and methylations in the human genome.
Zhibin Wang, Chongzhi Zang, Jeffrey A Rosenfeld, Dustin E Schones, Artem Barski, Suresh Cuddapah, Kairong Cui, Tae-Young Roh, Weiqun Peng, Michael Q Zhang,[...]. Nat Genet 2008
15

The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure.
Brendan Jones, Hui Su, Audesh Bhat, Hong Lei, Jeffrey Bajko, Sarah Hevi, Gretchen A Baltus, Shilpa Kadam, Huili Zhai, Reginald Valdez,[...]. PLoS Genet 2008
229
15

The PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesis.
Andrew G Muntean, Jiaying Tan, Kajal Sitwala, Yongsheng Huang, Joel Bronstein, James A Connelly, Venkatesha Basrur, Kojo S J Elenitoba-Johnson, Jay L Hess. Cancer Cell 2010
158
15

Abrogation of MLL-AF10 and CALM-AF10-mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l.
L Chen, A J Deshpande, D Banka, K M Bernt, S Dias, C Buske, E J Olhava, S R Daigle, V M Richon, R M Pollock,[...]. Leukemia 2013
97
15

Altered Hox expression and segmental identity in Mll-mutant mice.
B D Yu, J L Hess, S E Horning, G A Brown, S J Korsmeyer. Nature 1995
679
14

Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding.
Benjamin I Leach, Aravinda Kuntimaddi, Charles R Schmidt, Tomasz Cierpicki, Stephanie A Johnson, John H Bushweller. Structure 2013
62
22

Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression.
Akihiko Yokoyama, Zhong Wang, Joanna Wysocka, Mrinmoy Sanyal, Deborah J Aufiero, Issay Kitabayashi, Winship Herr, Michael L Cleary. Mol Cell Biol 2004
504
14

Functional interdependence of BRD4 and DOT1L in MLL leukemia.
Omer Gilan, Enid Y N Lam, Isabelle Becher, Dave Lugo, Ester Cannizzaro, Gerard Joberty, Aoife Ward, Meike Wiese, Chun Yew Fong, Sarah Ftouni,[...]. Nat Struct Mol Biol 2016
61
22

Transcription control by the ENL YEATS domain in acute leukaemia.
Michael A Erb, Thomas G Scott, Bin E Li, Huafeng Xie, Joshiawa Paulk, Hyuk-Soo Seo, Amanda Souza, Justin M Roberts, Shiva Dastjerdi, Dennis L Buckley,[...]. Nature 2017
127
14

Cooperative gene activation by AF4 and DOT1L drives MLL-rearranged leukemia.
Hiroshi Okuda, Boban Stanojevic, Akinori Kanai, Takeshi Kawamura, Satoshi Takahashi, Hirotaka Matsui, Akifumi Takaori-Kondo, Akihiko Yokoyama. J Clin Invest 2017
35
40


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.