A citation-based method for searching scientific literature

Shahab Akhoondi, Dahui Sun, Natalie von der Lehr, Sophia Apostolidou, Kathleen Klotz, Alena Maljukova, Diana Cepeda, Heidi Fiegl, Dimitra Dafou, Christian Marth, Elisabeth Mueller-Holzner, Martin Corcoran, Markus Dagnell, Sepideh Zabihi Nejad, Babak Noori Nayer, Mohammad Reza Zali, Johan Hansson, Susanne Egyhazi, Fredrik Petersson, Per Sangfelt, Hans Nordgren, Dan Grander, Steven I Reed, Martin Widschwendter, Olle Sangfelt, Charles Spruck. Cancer Res 2007
Times Cited: 369







List of co-cited articles
974 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.
Masayoshi Yada, Shigetsugu Hatakeyama, Takumi Kamura, Masaaki Nishiyama, Ryosuke Tsunematsu, Hiroyuki Imaki, Noriko Ishida, Fumihiko Okumura, Keiko Nakayama, Keiichi I Nakayama. EMBO J 2004
575
23

FBXW7: a critical tumor suppressor of human cancers.
Chien-Hung Yeh, Marcia Bellon, Christophe Nicot. Mol Cancer 2018
199
21

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation.
Markus Welcker, Amir Orian, Jianping Jin, Jonathan E Grim, J Wade Harper, Robert N Eisenman, Bruce E Clurman. Proc Natl Acad Sci U S A 2004
651
20

The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability.
Bryan King, Thomas Trimarchi, Linsey Reavie, Luyao Xu, Jasper Mullenders, Panagiotis Ntziachristos, Beatriz Aranda-Orgilles, Arianne Perez-Garcia, Junwei Shi, Christopher Vakoc,[...]. Cell 2013
222
18

Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities.
Ryan J Davis, Markus Welcker, Bruce E Clurman. Cancer Cell 2014
235
16

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
Jennifer O'Neil, Jonathan Grim, Peter Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James Hardwick, Markus Welcker, Jules P Meijerink, Rob Pieters,[...]. J Exp Med 2007
499
16

Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases.
Bing Hao, Stephanie Oehlmann, Mathew E Sowa, J Wade Harper, Nikola P Pavletich. Mol Cell 2007
331
16

FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression.
Jian-Hua Mao, Il-Jin Kim, Di Wu, Joan Climent, Hio Chung Kang, Reyno DelRosario, Allan Balmain. Science 2008
311
16

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase.
D M Koepp, L K Schaefer, X Ye, K Keyomarsi, C Chu, J W Harper, S J Elledge. Science 2001
628
14

Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer.
Shahab Akhoondi, Linda Lindström, Martin Widschwendter, Martin Corcoran, Jonas Bergh, Charles Spruck, Dan Grandér, Olle Sangfelt. Breast Cancer Res 2010
60
21

Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene.
Jian-Hua Mao, Jesus Perez-Losada, Di Wu, Reyno Delrosario, Ryosuke Tsunematsu, Keiichi I Nakayama, Ken Brown, Sheila Bryson, Allan Balmain. Nature 2004
306
13

SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
Hiroyuki Inuzuka, Shavali Shaik, Ichiro Onoyama, Daming Gao, Alan Tseng, Richard S Maser, Bo Zhai, Lixin Wan, Alejandro Gutierrez, Alan W Lau,[...]. Nature 2011
474
13

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line.
H Strohmaier, C H Spruck, P Kaiser, K A Won, O Sangfelt, S I Reed. Nature 2001
489
12

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
12

Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7.
Ingrid E Wertz, Saritha Kusam, Cynthia Lam, Toru Okamoto, Wendy Sandoval, Daniel J Anderson, Elizabeth Helgason, James A Ernst, Mike Eby, Jinfeng Liu,[...]. Nature 2011
575
12

The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia.
Benjamin J Thompson, Silvia Buonamici, Maria Luisa Sulis, Teresa Palomero, Tomas Vilimas, Giuseppe Basso, Adolfo Ferrando, Iannis Aifantis. J Exp Med 2007
351
11

Inactivation of hCDC4 can cause chromosomal instability.
Harith Rajagopalan, Prasad V Jallepalli, Carlo Rago, Victor E Velculescu, Kenneth W Kinzler, Bert Vogelstein, Christoph Lengauer. Nature 2004
439
11

hCDC4 gene mutations in endometrial cancer.
Charles H Spruck, Heimo Strohmaier, Olle Sangfelt, Hannes M Müller, Michael Hubalek, Elisabeth Müller-Holzner, Christian Marth, Martin Widschwendter, Steven I Reed. Cancer Res 2002
228
11

The tumor suppressor gene hCDC4 is frequently mutated in human T-cell acute lymphoblastic leukemia with functional consequences for Notch signaling.
Alena Malyukova, Takeaki Dohda, Natalie von der Lehr, Shahab Akhoondi, Martin Corcoran, Mats Heyman, Charles Spruck, Dan Grandér, Urban Lendahl, Olle Sangfelt. Cancer Res 2007
146
11

The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase.
Wenyi Wei, Jianping Jin, Susanne Schlisio, J Wade Harper, William G Kaelin. Cancer Cell 2005
321
11

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data.
Ethan Cerami, Jianjiong Gao, Ugur Dogrusoz, Benjamin E Gross, Selcuk Onur Sumer, Bülent Arman Aksoy, Anders Jacobsen, Caitlin J Byrne, Michael L Heuer, Erik Larsson,[...]. Cancer Discov 2012
11

Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal.
Jianjiong Gao, Bülent Arman Aksoy, Ugur Dogrusoz, Gideon Dresdner, Benjamin Gross, S Onur Sumer, Yichao Sun, Anders Jacobsen, Rileen Sinha, Erik Larsson,[...]. Sci Signal 2013
11


FBXW7 missense mutation: a novel negative prognostic factor in metastatic colorectal adenocarcinoma.
Krittiya Korphaisarn, Van Karlyle Morris, Michael J Overman, David R Fogelman, Bryan K Kee, Kanwal Pratap Singh Raghav, Shanequa Manuel, Imad Shureiqi, Robert A Wolff, Cathy Eng,[...]. Oncotarget 2017
40
25

Fbxw7 Tumor Suppressor: A Vital Regulator Contributes to Human Tumorigenesis.
Jun Cao, Ming-Hua Ge, Zhi-Qiang Ling. Medicine (Baltimore) 2016
56
17

FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation.
Roya Babaei-Jadidi, Ningning Li, Anas Saadeddin, Bradley Spencer-Dene, Anett Jandke, Belal Muhammad, ElSayed E Ibrahim, Ranjithmenon Muraleedharan, Mohammed Abuzinadah, Hayley Davis,[...]. J Exp Med 2011
132
10

FBXW7 modulates cellular stress response and metastatic potential through ​HSF1 post-translational modification.
Nikos Kourtis, Rana S Moubarak, Beatriz Aranda-Orgilles, Kevin Lui, Iraz T Aydin, Thomas Trimarchi, Farbod Darvishian, Christine Salvaggio, Judy Zhong, Kamala Bhatt,[...]. Nat Cell Biol 2015
74
13

F-box protein FBXW7 inhibits cancer metastasis in a non-cell-autonomous manner.
Kanae Yumimoto, Sayuri Akiyoshi, Hiroki Ueo, Yasuaki Sagara, Ichiro Onoyama, Hiroaki Ueo, Shinji Ohno, Masaki Mori, Koshi Mimori, Keiichi I Nakayama. J Clin Invest 2015
77
11

FBXW7 mutations in melanoma and a new therapeutic paradigm.
Iraz T Aydin, Rachel D Melamed, Sarah J Adams, Mireia Castillo-Martin, Ahu Demir, Diana Bryk, Georg Brunner, Carlos Cordon-Cardo, Iman Osman, Raul Rabadan,[...]. J Natl Cancer Inst 2014
67
13

Ubiquitin ligases: cell-cycle control and cancer.
Keiichi I Nakayama, Keiko Nakayama. Nat Rev Cancer 2006
9

Fbw7 and p53 cooperatively suppress advanced and chromosomally unstable intestinal cancer.
Jonathan E Grim, Sue E Knoblaugh, Katherine A Guthrie, Amanda Hagar, Jherek Swanger, Jessica Hespelt, Jeffrey J Delrow, Tom Small, William M Grady, Keiichi I Nakayama,[...]. Mol Cell Biol 2012
63
14


Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis.
Ichiro Onoyama, Ryosuke Tsunematsu, Akinobu Matsumoto, Taichi Kimura, Ignacio Moreno de Alborán, Keiko Nakayama, Keiichi I Nakayama. J Exp Med 2007
149
9

F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor.
Rocio Sancho, Anett Jandke, Hayley Davis, Markus E Diefenbacher, Ian Tomlinson, Axel Behrens. Gastroenterology 2010
93
9

Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase.
Sang-Hyun Min, Alan W Lau, Tae Ho Lee, Hiroyuki Inuzuka, Shuo Wei, Pengyu Huang, Shavali Shaik, Daniel Yenhong Lee, Greg Finn, Martin Balastik,[...]. Mol Cell 2012
119
9

Loss of FBXW7, a cell cycle regulating gene, in colorectal cancer: clinical significance.
Masaaki Iwatsuki, Koshi Mimori, Hideshi Ishii, Takehiko Yokobori, Yasushi Takatsuno, Tetsuya Sato, Hiroyuki Toh, Ichiro Onoyama, Keiichi I Nakayama, Hideo Baba,[...]. Int J Cancer 2010
111
9

The ubiquitin system.
A Hershko, A Ciechanover. Annu Rev Biochem 1998
9


SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box.
C Bai, P Sen, K Hofmann, L Ma, M Goebl, J W Harper, S J Elledge. Cell 1996
9

Systematic analysis and nomenclature of mammalian F-box proteins.
Jianping Jin, Timothy Cardozo, Ruth C Lovering, Stephen J Elledge, Michele Pagano, J Wade Harper. Genes Dev 2004
513
9

hCDC4b, a regulator of cyclin E, as a direct transcriptional target of p53.
Takashi Kimura, Mitsukazu Gotoh, Yusuke Nakamura, Hirofumi Arakawa. Cancer Sci 2003
93
8

Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma.
Luca Busino, Scott E Millman, Luigi Scotto, Christos A Kyratsous, Venkatesha Basrur, Owen O'Connor, Alexander Hoffmann, Kojo S Elenitoba-Johnson, Michele Pagano. Nat Cell Biol 2012
133
8

Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase.
Stephen Orlicky, Xiaojing Tang, Andrew Willems, Mike Tyers, Frank Sicheri. Cell 2003
408
8

Oncogenic mutations in the FBXW7 gene of adult T-cell leukemia patients.
Chien-Hung Yeh, Marcia Bellon, Joanna Pancewicz-Wojtkiewicz, Christophe Nicot. Proc Natl Acad Sci U S A 2016
52
15

Fbw7 dimerization determines the specificity and robustness of substrate degradation.
Markus Welcker, Elizabeth A Larimore, Jherek Swanger, Maria T Bengoechea-Alonso, Jonathan E Grim, Johan Ericsson, Ning Zheng, Bruce E Clurman. Genes Dev 2013
66
12

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Andrew P Weng, Adolfo A Ferrando, Woojoong Lee, John P Morris, Lewis B Silverman, Cheryll Sanchez-Irizarry, Stephen C Blacklow, A Thomas Look, Jon C Aster. Science 2004
8

A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size.
Markus Welcker, Amir Orian, Jonathan E Grim, Robert N Eisenman, Bruce E Clurman. Curr Biol 2004
235
8

Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication.
K Nakayama, H Nagahama, Y A Minamishima, M Matsumoto, I Nakamichi, K Kitagawa, M Shirane, R Tsunematsu, T Tsukiyama, N Ishida,[...]. EMBO J 2000
608
8

FBXW7 in Cancer: What Has Been Unraveled Thus Far?
Bethsebie Lalduhsaki Sailo, Kishore Banik, Sosmitha Girisa, Devivasha Bordoloi, Lu Fan, Clarissa Esmeralda Halim, Hong Wang, Alan Prem Kumar, Dali Zheng, Xinliang Mao,[...]. Cancers (Basel) 2019
81
9


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.