Magnus Ingelman-Sundberg, Sarah C Sim, Alvin Gomez, Cristina Rodriguez-Antona. Pharmacol Ther 2007
Times Cited: 770
Times Cited: 770
Times Cited
Times Co-cited
Similarity
Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation.
Ulrich M Zanger, Matthias Schwab. Pharmacol Ther 2013
Ulrich M Zanger, Matthias Schwab. Pharmacol Ther 2013
30
Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity.
M Ingelman-Sundberg. Pharmacogenomics J 2005
M Ingelman-Sundberg. Pharmacogenomics J 2005
22
Prediction of CYP2D6 phenotype from genotype across world populations.
Andrea Gaedigk, Katrin Sangkuhl, Michelle Whirl-Carrillo, Teri Klein, J Steven Leeder. Genet Med 2017
Andrea Gaedigk, Katrin Sangkuhl, Michelle Whirl-Carrillo, Teri Klein, J Steven Leeder. Genet Med 2017
15
Polymorphism of human cytochrome P450 2D6 and its clinical significance: Part I.
Shu-Feng Zhou. Clin Pharmacokinet 2009
Shu-Feng Zhou. Clin Pharmacokinet 2009
11
Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update.
J K Hicks, K Sangkuhl, J J Swen, V L Ellingrod, D J Müller, K Shimoda, J R Bishop, E D Kharasch, T C Skaar, A Gaedigk,[...]. Clin Pharmacol Ther 2017
J K Hicks, K Sangkuhl, J J Swen, V L Ellingrod, D J Müller, K Shimoda, J R Bishop, E D Kharasch, T C Skaar, A Gaedigk,[...]. Clin Pharmacol Ther 2017
11
The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype.
A Gaedigk, S D Simon, R E Pearce, L D Bradford, M J Kennedy, J S Leeder. Clin Pharmacol Ther 2008
A Gaedigk, S D Simon, R E Pearce, L D Bradford, M J Kennedy, J S Leeder. Clin Pharmacol Ther 2008
11
Pharmacogenetics: from bench to byte--an update of guidelines.
J J Swen, M Nijenhuis, A de Boer, L Grandia, A H Maitland-van der Zee, H Mulder, G A P J M Rongen, R H N van Schaik, T Schalekamp, D J Touw,[...]. Clin Pharmacol Ther 2011
J J Swen, M Nijenhuis, A de Boer, L Grandia, A H Maitland-van der Zee, H Mulder, G A P J M Rongen, R H N van Schaik, T Schalekamp, D J Touw,[...]. Clin Pharmacol Ther 2011
10
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors.
J K Hicks, J R Bishop, K Sangkuhl, D J Müller, Y Ji, S G Leckband, J S Leeder, R L Graham, D L Chiulli, A LLerena,[...]. Clin Pharmacol Ther 2015
J K Hicks, J R Bishop, K Sangkuhl, D J Müller, Y Ji, S G Leckband, J S Leeder, R L Graham, D L Chiulli, A LLerena,[...]. Clin Pharmacol Ther 2015
10
Polymorphism of human cytochrome P450 2D6 and its clinical significance: part II.
Shu-Feng Zhou. Clin Pharmacokinet 2009
Shu-Feng Zhou. Clin Pharmacokinet 2009
9
Polymorphism of human cytochrome P450 enzymes and its clinical impact.
Shu-Feng Zhou, Jun-Ping Liu, Balram Chowbay. Drug Metab Rev 2009
Shu-Feng Zhou, Jun-Ping Liu, Balram Chowbay. Drug Metab Rev 2009
9
Applications of CYP450 testing in the clinical setting.
C F Samer, K Ing Lorenzini, V Rollason, Y Daali, J A Desmeules. Mol Diagn Ther 2013
C F Samer, K Ing Lorenzini, V Rollason, Y Daali, J A Desmeules. Mol Diagn Ther 2013
9
The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database.
Andrea Gaedigk, Magnus Ingelman-Sundberg, Neil A Miller, J Steven Leeder, Michelle Whirl-Carrillo, Teri E Klein. Clin Pharmacol Ther 2018
Andrea Gaedigk, Magnus Ingelman-Sundberg, Neil A Miller, J Steven Leeder, Michelle Whirl-Carrillo, Teri E Klein. Clin Pharmacol Ther 2018
9
Pharmacogenetics of cytochrome P450 and its applications in drug therapy: the past, present and future.
Magnus Ingelman-Sundberg. Trends Pharmacol Sci 2004
Magnus Ingelman-Sundberg. Trends Pharmacol Sci 2004
9
Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450 2D6 genotype and codeine therapy: 2014 update.
K R Crews, A Gaedigk, H M Dunnenberger, J S Leeder, T E Klein, K E Caudle, C E Haidar, D D Shen, J T Callaghan, S Sadhasivam,[...]. Clin Pharmacol Ther 2014
K R Crews, A Gaedigk, H M Dunnenberger, J S Leeder, T E Klein, K E Caudle, C E Haidar, D D Shen, J T Callaghan, S Sadhasivam,[...]. Clin Pharmacol Ther 2014
8
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and Tamoxifen Therapy.
Matthew P Goetz, Katrin Sangkuhl, Henk-Jan Guchelaar, Matthias Schwab, Michael Province, Michelle Whirl-Carrillo, W Fraser Symmans, Howard L McLeod, Mark J Ratain, Hitoshi Zembutsu,[...]. Clin Pharmacol Ther 2018
Matthew P Goetz, Katrin Sangkuhl, Henk-Jan Guchelaar, Matthias Schwab, Michael Province, Michelle Whirl-Carrillo, W Fraser Symmans, Howard L McLeod, Mark J Ratain, Hitoshi Zembutsu,[...]. Clin Pharmacol Ther 2018
8
Standardizing terms for clinical pharmacogenetic test results: consensus terms from the Clinical Pharmacogenetics Implementation Consortium (CPIC).
Kelly E Caudle, Henry M Dunnenberger, Robert R Freimuth, Josh F Peterson, Jonathan D Burlison, Michelle Whirl-Carrillo, Stuart A Scott, Heidi L Rehm, Marc S Williams, Teri E Klein,[...]. Genet Med 2017
Kelly E Caudle, Henry M Dunnenberger, Robert R Freimuth, Josh F Peterson, Jonathan D Burlison, Michelle Whirl-Carrillo, Stuart A Scott, Heidi L Rehm, Marc S Williams, Teri E Klein,[...]. Genet Med 2017
8
Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.
Y Zhou, M Ingelman-Sundberg, V M Lauschke. Clin Pharmacol Ther 2017
Y Zhou, M Ingelman-Sundberg, V M Lauschke. Clin Pharmacol Ther 2017
8
Pharmacogenomics and individualized drug therapy.
Michel Eichelbaum, Magnus Ingelman-Sundberg, William E Evans. Annu Rev Med 2006
Michel Eichelbaum, Magnus Ingelman-Sundberg, William E Evans. Annu Rev Med 2006
8
CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants.
L DiAnne Bradford. Pharmacogenomics 2002
L DiAnne Bradford. Pharmacogenomics 2002
8
Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response.
J Kirchheiner, K Nickchen, M Bauer, M-L Wong, J Licinio, I Roots, J Brockmöller. Mol Psychiatry 2004
J Kirchheiner, K Nickchen, M Bauer, M-L Wong, J Licinio, I Roots, J Brockmöller. Mol Psychiatry 2004
7
Interethnic variability of CYP2D6 alleles and of predicted and measured metabolic phenotypes across world populations.
Adrián LLerena, Maria Eugenia G Naranjo, Fernanda Rodrigues-Soares, Eva M Penas-LLedó, Humberto Fariñas, Eduardo Tarazona-Santos. Expert Opin Drug Metab Toxicol 2014
Adrián LLerena, Maria Eugenia G Naranjo, Fernanda Rodrigues-Soares, Eva M Penas-LLedó, Humberto Fariñas, Eduardo Tarazona-Santos. Expert Opin Drug Metab Toxicol 2014
7
Standardizing CYP2D6 Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and Dutch Pharmacogenetics Working Group.
Kelly E Caudle, Katrin Sangkuhl, Michelle Whirl-Carrillo, Jesse J Swen, Cyrine E Haidar, Teri E Klein, Roseann S Gammal, Mary V Relling, Stuart A Scott, Daniel L Hertz,[...]. Clin Transl Sci 2020
Kelly E Caudle, Katrin Sangkuhl, Michelle Whirl-Carrillo, Jesse J Swen, Cyrine E Haidar, Teri E Klein, Roseann S Gammal, Mary V Relling, Stuart A Scott, Daniel L Hertz,[...]. Clin Transl Sci 2020
7
Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation.
Ulrich M Zanger, Miia Turpeinen, Kathrin Klein, Matthias Schwab. Anal Bioanal Chem 2008
Ulrich M Zanger, Miia Turpeinen, Kathrin Klein, Matthias Schwab. Anal Bioanal Chem 2008
6
Genetic variability of drug-metabolizing enzymes: the dual impact on psychiatric therapy and regulation of brain function.
J C Stingl, J Brockmöller, R Viviani. Mol Psychiatry 2013
J C Stingl, J Brockmöller, R Viviani. Mol Psychiatry 2013
6
Comparison of the Guidelines of the Clinical Pharmacogenetics Implementation Consortium and the Dutch Pharmacogenetics Working Group.
P C D Bank, K E Caudle, J J Swen, R S Gammal, M Whirl-Carrillo, T E Klein, M V Relling, H-J Guchelaar. Clin Pharmacol Ther 2018
P C D Bank, K E Caudle, J J Swen, R S Gammal, M Whirl-Carrillo, T E Klein, M V Relling, H-J Guchelaar. Clin Pharmacol Ther 2018
6
Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry.
Ulrich M Zanger, Sebastian Raimundo, Michel Eichelbaum. Naunyn Schmiedebergs Arch Pharmacol 2004
Ulrich M Zanger, Sebastian Raimundo, Michel Eichelbaum. Naunyn Schmiedebergs Arch Pharmacol 2004
6
CYP2D6 worldwide genetic variation shows high frequency of altered activity variants and no continental structure.
Johanna Sistonen, Antti Sajantila, Oscar Lao, Jukka Corander, Guido Barbujani, Silvia Fuselli. Pharmacogenet Genomics 2007
Johanna Sistonen, Antti Sajantila, Oscar Lao, Jukka Corander, Guido Barbujani, Silvia Fuselli. Pharmacogenet Genomics 2007
6
Cytochrome P450 2C9-CYP2C9.
Derek Van Booven, Sharon Marsh, Howard McLeod, Michelle Whirl Carrillo, Katrin Sangkuhl, Teri E Klein, Russ B Altman. Pharmacogenet Genomics 2010
Derek Van Booven, Sharon Marsh, Howard McLeod, Michelle Whirl Carrillo, Katrin Sangkuhl, Teri E Klein, Russ B Altman. Pharmacogenet Genomics 2010
6
Genetic variation in the CYP2D6 gene is associated with a lower heart rate and blood pressure in beta-blocker users.
M J Bijl, L E Visser, R H N van Schaik, J A Kors, J C M Witteman, A Hofman, A G Vulto, T van Gelder, B H Ch Stricker. Clin Pharmacol Ther 2009
M J Bijl, L E Visser, R H N van Schaik, J A Kors, J C M Witteman, A Hofman, A G Vulto, T van Gelder, B H Ch Stricker. Clin Pharmacol Ther 2009
5
Challenges in CYP2D6 phenotype assignment from genotype data: a critical assessment and call for standardization.
J Kevin Hicks, Jesse J Swen, Andrea Gaedigk. Curr Drug Metab 2014
J Kevin Hicks, Jesse J Swen, Andrea Gaedigk. Curr Drug Metab 2014
5
Pharmacogenetics, drug-metabolizing enzymes, and clinical practice.
Sharon J Gardiner, Evan J Begg. Pharmacol Rev 2006
Sharon J Gardiner, Evan J Begg. Pharmacol Rev 2006
5
Clinical Pharmacogenetics Implementation Consortium guidelines for CYP2C19 genotype and clopidogrel therapy: 2013 update.
S A Scott, K Sangkuhl, C M Stein, J-S Hulot, J L Mega, D M Roden, T E Klein, M S Sabatine, J A Johnson, A R Shuldiner. Clin Pharmacol Ther 2013
S A Scott, K Sangkuhl, C M Stein, J-S Hulot, J L Mega, D M Roden, T E Klein, M S Sabatine, J A Johnson, A R Shuldiner. Clin Pharmacol Ther 2013
5
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Pharmacogenetics-Guided Warfarin Dosing: 2017 Update.
J A Johnson, K E Caudle, L Gong, M Whirl-Carrillo, C M Stein, S A Scott, M T Lee, B F Gage, S E Kimmel, M A Perera,[...]. Clin Pharmacol Ther 2017
J A Johnson, K E Caudle, L Gong, M Whirl-Carrillo, C M Stein, S A Scott, M T Lee, B F Gage, S E Kimmel, M A Perera,[...]. Clin Pharmacol Ther 2017
5
Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences.
C Sachse, J Brockmöller, S Bauer, I Roots. Am J Hum Genet 1997
C Sachse, J Brockmöller, S Bauer, I Roots. Am J Hum Genet 1997
5
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP3A5 Genotype and Tacrolimus Dosing.
K A Birdwell, B Decker, J M Barbarino, J F Peterson, C M Stein, W Sadee, D Wang, A A Vinks, Y He, J J Swen,[...]. Clin Pharmacol Ther 2015
K A Birdwell, B Decker, J M Barbarino, J F Peterson, C M Stein, W Sadee, D Wang, A A Vinks, Y He, J J Swen,[...]. Clin Pharmacol Ther 2015
5
Clinical Pharmacogenetics Implementation Consortium guideline for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants.
J K Hicks, J J Swen, C F Thorn, K Sangkuhl, E D Kharasch, V L Ellingrod, T C Skaar, D J Müller, A Gaedigk, J C Stingl. Clin Pharmacol Ther 2013
J K Hicks, J J Swen, C F Thorn, K Sangkuhl, E D Kharasch, V L Ellingrod, T C Skaar, D J Müller, A Gaedigk, J C Stingl. Clin Pharmacol Ther 2013
5
Moving towards individualized medicine with pharmacogenomics.
William E Evans, Mary V Relling. Nature 2004
William E Evans, Mary V Relling. Nature 2004
5
CYP2C9, CYPC19 and CYP2D6 gene profiles and gene susceptibility to drug response and toxicity in Turkish population.
Merve Arici, Gül Özhan. Saudi Pharm J 2017
Merve Arici, Gül Özhan. Saudi Pharm J 2017
38
Pharmacogenomics: translating functional genomics into rational therapeutics.
W E Evans, M V Relling. Science 1999
W E Evans, M V Relling. Science 1999
5
PharmVar GeneFocus: CYP2D6.
Charity Nofziger, Amy J Turner, Katrin Sangkuhl, Michelle Whirl-Carrillo, José A G Agúndez, John L Black, Henry M Dunnenberger, Gualberto Ruano, Martin A Kennedy, Michael S Phillips,[...]. Clin Pharmacol Ther 2020
Charity Nofziger, Amy J Turner, Katrin Sangkuhl, Michelle Whirl-Carrillo, José A G Agúndez, John L Black, Henry M Dunnenberger, Gualberto Ruano, Martin A Kennedy, Michael S Phillips,[...]. Clin Pharmacol Ther 2020
6
Inhibition and induction of human cytochrome P450 enzymes: current status.
Olavi Pelkonen, Miia Turpeinen, Jukka Hakkola, Paavo Honkakoski, Janne Hukkanen, Hannu Raunio. Arch Toxicol 2008
Olavi Pelkonen, Miia Turpeinen, Jukka Hakkola, Paavo Honkakoski, Janne Hukkanen, Hannu Raunio. Arch Toxicol 2008
5
CYP2D6 is a major determinant of metoprolol disposition and effects in hospitalized Russian patients treated for acute myocardial infarction.
Ksenia Goryachkina, Aleksandra Burbello, Svetlana Boldueva, Svetlana Babak, Ulf Bergman, Leif Bertilsson. Eur J Clin Pharmacol 2008
Ksenia Goryachkina, Aleksandra Burbello, Svetlana Boldueva, Svetlana Babak, Ulf Bergman, Leif Bertilsson. Eur J Clin Pharmacol 2008
8
Impact of the CYP2D6 genotype on the clinical effects of metoprolol: a prospective longitudinal study.
T Rau, H Wuttke, L M Michels, U Werner, K Bergmann, M Kreft, M F Fromm, T Eschenhagen. Clin Pharmacol Ther 2009
T Rau, H Wuttke, L M Michels, U Werner, K Bergmann, M Kreft, M F Fromm, T Eschenhagen. Clin Pharmacol Ther 2009
4
Recommendations for Clinical CYP2C19 Genotyping Allele Selection: A Report of the Association for Molecular Pathology.
Victoria M Pratt, Andria L Del Tredici, Houda Hachad, Yuan Ji, Lisa V Kalman, Stuart A Scott, Karen E Weck. J Mol Diagn 2018
Victoria M Pratt, Andria L Del Tredici, Houda Hachad, Yuan Ji, Lisa V Kalman, Stuart A Scott, Karen E Weck. J Mol Diagn 2018
6
Mechanisms of cytochrome P450 induction.
Leslie M Tompkins, Andrew D Wallace. J Biochem Mol Toxicol 2007
Leslie M Tompkins, Andrew D Wallace. J Biochem Mol Toxicol 2007
4
Interindividual Variability in Cytochrome P450-Mediated Drug Metabolism.
Timothy S Tracy, Amarjit S Chaudhry, Bhagwat Prasad, Kenneth E Thummel, Erin G Schuetz, Xiao-Bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M Shireman,[...]. Drug Metab Dispos 2016
Timothy S Tracy, Amarjit S Chaudhry, Bhagwat Prasad, Kenneth E Thummel, Erin G Schuetz, Xiao-Bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M Shireman,[...]. Drug Metab Dispos 2016
4
Population differences in major functional polymorphisms of pharmacokinetics/pharmacodynamics-related genes in Eastern Asians and Europeans: implications in the clinical trials for novel drug development.
Kouichi Kurose, Emiko Sugiyama, Yoshiro Saito. Drug Metab Pharmacokinet 2012
Kouichi Kurose, Emiko Sugiyama, Yoshiro Saito. Drug Metab Pharmacokinet 2012
4
Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450-2C19 (CYP2C19) genotype and clopidogrel therapy.
S A Scott, K Sangkuhl, E E Gardner, C M Stein, J-S Hulot, J A Johnson, D M Roden, T E Klein, A R Shuldiner. Clin Pharmacol Ther 2011
S A Scott, K Sangkuhl, E E Gardner, C M Stein, J-S Hulot, J A Johnson, D M Roden, T E Klein, A R Shuldiner. Clin Pharmacol Ther 2011
4
CYP2C9 polymorphism analysis in Han Chinese populations: building the largest allele frequency database.
D-P Dai, R-A Xu, L-M Hu, S-H Wang, P-W Geng, J-F Yang, L-P Yang, J-C Qian, Z-S Wang, G-H Zhu,[...]. Pharmacogenomics J 2014
D-P Dai, R-A Xu, L-M Hu, S-H Wang, P-W Geng, J-F Yang, L-P Yang, J-C Qian, Z-S Wang, G-H Zhu,[...]. Pharmacogenomics J 2014
4
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.