Cristina A de Frutos, Sonia Vega, Miguel Manzanares, Juana M Flores, Hector Huertas, M Luisa Martínez-Frías, M Angela Nieto. Dev Cell 2007
Times Cited: 68
Times Cited: 68
Times Cited
Times Co-cited
Similarity
Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype.
Shunichi Murakami, Gener Balmes, Sandra McKinney, Zhaoping Zhang, David Givol, Benoit de Crombrugghe. Genes Dev 2004
Shunichi Murakami, Gener Balmes, Sandra McKinney, Zhaoping Zhang, David Givol, Benoit de Crombrugghe. Genes Dev 2004
30
Overexpression of CNP in chondrocytes rescues achondroplasia through a MAPK-dependent pathway.
Akihiro Yasoda, Yasato Komatsu, Hideki Chusho, Takashi Miyazawa, Ami Ozasa, Masako Miura, Tatsuya Kurihara, Tomohiro Rogi, Shoji Tanaka, Michio Suda,[...]. Nat Med 2004
Akihiro Yasoda, Yasato Komatsu, Hideki Chusho, Takashi Miyazawa, Ami Ozasa, Masako Miura, Tatsuya Kurihara, Tomohiro Rogi, Shoji Tanaka, Michio Suda,[...]. Nat Med 2004
26
Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3.
J S Colvin, B A Bohne, G W Harding, D G McEwen, D M Ornitz. Nat Genet 1996
J S Colvin, B A Bohne, G W Harding, D G McEwen, D M Ornitz. Nat Genet 1996
25
Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18.
Zhonghao Liu, Jingsong Xu, Jennifer S Colvin, David M Ornitz. Genes Dev 2002
Zhonghao Liu, Jingsong Xu, Jennifer S Colvin, David M Ornitz. Genes Dev 2002
23
Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism.
W C Su, M Kitagawa, N Xue, B Xie, S Garofalo, J Cho, C Deng, W A Horton, X Y Fu. Nature 1997
W C Su, M Kitagawa, N Xue, B Xie, S Garofalo, J Cho, C Deng, W A Horton, X Y Fu. Nature 1997
20
Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3.
M C Naski, J S Colvin, J D Coffin, D M Ornitz. Development 1998
M C Naski, J S Colvin, J D Coffin, D M Ornitz. Development 1998
20
FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease.
David M Ornitz, Pierre J Marie. Genes Dev 2002
David M Ornitz, Pierre J Marie. Genes Dev 2002
19
Interaction of FGF, Ihh/Pthlh, and BMP signaling integrates chondrocyte proliferation and hypertrophic differentiation.
Eleonora Minina, Conny Kreschel, Michael C Naski, David M Ornitz, Andrea Vortkamp. Dev Cell 2002
Eleonora Minina, Conny Kreschel, Michael C Naski, David M Ornitz, Andrea Vortkamp. Dev Cell 2002
19
Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein.
A Vortkamp, K Lee, B Lanske, G V Segre, H M Kronenberg, C J Tabin. Science 1996
A Vortkamp, K Lee, B Lanske, G V Segre, H M Kronenberg, C J Tabin. Science 1996
19
Mouse Snail family transcription repressors regulate chondrocyte, extracellular matrix, type II collagen, and aggrecan.
Kenji Seki, Toshihiko Fujimori, Pierre Savagner, Akiko Hata, Tomonao Aikawa, Naoshi Ogata, Yoichi Nabeshima, Lee Kaechoong. J Biol Chem 2003
Kenji Seki, Toshihiko Fujimori, Pierre Savagner, Akiko Hata, Tomonao Aikawa, Naoshi Ogata, Yoichi Nabeshima, Lee Kaechoong. J Biol Chem 2003
19
A Lys644Glu substitution in fibroblast growth factor receptor 3 (FGFR3) causes dwarfism in mice by activation of STATs and ink4 cell cycle inhibitors.
C Li, L Chen, T Iwata, M Kitagawa, X Y Fu, C X Deng. Hum Mol Genet 1999
C Li, L Chen, T Iwata, M Kitagawa, X Y Fu, C X Deng. Hum Mol Genet 1999
19
A neonatal lethal mutation in FGFR3 uncouples proliferation and differentiation of growth plate chondrocytes in embryos.
T Iwata, L Chen, C Li, D A Ovchinnikov, R R Behringer, C A Francomano, C X Deng. Hum Mol Genet 2000
T Iwata, L Chen, C Li, D A Ovchinnikov, R R Behringer, C A Francomano, C X Deng. Hum Mol Genet 2000
19
FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway.
M Sahni, D C Ambrosetti, A Mansukhani, R Gertner, D Levy, C Basilico. Genes Dev 1999
M Sahni, D C Ambrosetti, A Mansukhani, R Gertner, D Levy, C Basilico. Genes Dev 1999
19
Mutations in the gene encoding fibroblast growth factor receptor-3 in achondroplasia.
F Rousseau, J Bonaventure, L Legeai-Mallet, A Pelet, J M Rozet, P Maroteaux, M Le Merrer, A Munnich. Nature 1994
F Rousseau, J Bonaventure, L Legeai-Mallet, A Pelet, J M Rozet, P Maroteaux, M Le Merrer, A Munnich. Nature 1994
19
Fibroblast growth factor receptor 3 is a negative regulator of bone growth.
C Deng, A Wynshaw-Boris, F Zhou, A Kuo, P Leder. Cell 1996
C Deng, A Wynshaw-Boris, F Zhou, A Kuo, P Leder. Cell 1996
19
A Ser(365)-->Cys mutation of fibroblast growth factor receptor 3 in mouse downregulates Ihh/PTHrP signals and causes severe achondroplasia.
L Chen, C Li, W Qiao, X Xu, C Deng. Hum Mol Genet 2001
L Chen, C Li, W Qiao, X Xu, C Deng. Hum Mol Genet 2001
19
FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod.
Irene H Hung, Kai Yu, Kory J Lavine, David M Ornitz. Dev Biol 2007
Irene H Hung, Kai Yu, Kory J Lavine, David M Ornitz. Dev Biol 2007
17
FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis.
Norihiko Ohbayashi, Masaki Shibayama, Yoko Kurotaki, Mayumi Imanishi, Toshihiko Fujimori, Nobuyuki Itoh, Shinji Takada. Genes Dev 2002
Norihiko Ohbayashi, Masaki Shibayama, Yoko Kurotaki, Mayumi Imanishi, Toshihiko Fujimori, Nobuyuki Itoh, Shinji Takada. Genes Dev 2002
17
FGF18 is required for early chondrocyte proliferation, hypertrophy and vascular invasion of the growth plate.
Zhonghao Liu, Kory J Lavine, Irene H Hung, David M Ornitz. Dev Biol 2007
Zhonghao Liu, Kory J Lavine, Irene H Hung, David M Ornitz. Dev Biol 2007
17
Interaction of fibroblast growth factor and C-natriuretic peptide signaling in regulation of chondrocyte proliferation and extracellular matrix homeostasis.
Pavel Krejci, Bernard Masri, Vincent Fontaine, Pertchoui B Mekikian, Maryann Weis, Herve Prats, William R Wilcox. J Cell Sci 2005
Pavel Krejci, Bernard Masri, Vincent Fontaine, Pertchoui B Mekikian, Maryann Weis, Herve Prats, William R Wilcox. J Cell Sci 2005
17
A network of transcriptional and signaling events is activated by FGF to induce chondrocyte growth arrest and differentiation.
Lisa Dailey, Emmanuel Laplantine, Riccardo Priore, Claudio Basilico. J Cell Biol 2003
Lisa Dailey, Emmanuel Laplantine, Riccardo Priore, Claudio Basilico. J Cell Biol 2003
17
Overexpression of FGFR3, Stat1, Stat5 and p21Cip1 correlates with phenotypic severity and defective chondrocyte differentiation in FGFR3-related chondrodysplasias.
L Legeai-Mallet, C Benoist-Lasselin, A Munnich, J Bonaventure. Bone 2004
L Legeai-Mallet, C Benoist-Lasselin, A Munnich, J Bonaventure. Bone 2004
17
Thanatophoric dysplasia (types I and II) caused by distinct mutations in fibroblast growth factor receptor 3.
P L Tavormina, R Shiang, L M Thompson, Y Z Zhu, D J Wilkin, R S Lachman, W R Wilcox, D L Rimoin, D H Cohn, J J Wasmuth. Nat Genet 1995
P L Tavormina, R Shiang, L M Thompson, Y Z Zhu, D J Wilkin, R S Lachman, W R Wilcox, D L Rimoin, D H Cohn, J J Wasmuth. Nat Genet 1995
17
A mouse model for achondroplasia produced by targeting fibroblast growth factor receptor 3.
Y Wang, M K Spatz, K Kannan, H Hayk, A Avivi, M Gorivodsky, M Pines, A Yayon, P Lonai, D Givol. Proc Natl Acad Sci U S A 1999
Y Wang, M K Spatz, K Kannan, H Hayk, A Avivi, M Gorivodsky, M Pines, A Yayon, P Lonai, D Givol. Proc Natl Acad Sci U S A 1999
17
FGF signaling in the developing endochondral skeleton.
David M Ornitz. Cytokine Growth Factor Rev 2005
David M Ornitz. Cytokine Growth Factor Rev 2005
16
Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia.
R Shiang, L M Thompson, Y Z Zhu, D M Church, T J Fielder, M Bocian, S T Winokur, J J Wasmuth. Cell 1994
R Shiang, L M Thompson, Y Z Zhu, D M Church, T J Fielder, M Bocian, S T Winokur, J J Wasmuth. Cell 1994
16
Gly369Cys mutation in mouse FGFR3 causes achondroplasia by affecting both chondrogenesis and osteogenesis.
L Chen, R Adar, X Yang, E O Monsonego, C Li, P V Hauschka, A Yayon, C X Deng. J Clin Invest 1999
L Chen, R Adar, X Yang, E O Monsonego, C Li, P V Hauschka, A Yayon, C X Deng. J Clin Invest 1999
16
Snail1 controls bone mass by regulating Runx2 and VDR expression during osteoblast differentiation.
Cristina A de Frutos, Romain Dacquin, Sonia Vega, Pierre Jurdic, Irma Machuca-Gayet, M Angela Nieto. EMBO J 2009
Cristina A de Frutos, Romain Dacquin, Sonia Vega, Pierre Jurdic, Irma Machuca-Gayet, M Angela Nieto. EMBO J 2009
25
Cellular signaling by fibroblast growth factor receptors.
V P Eswarakumar, I Lax, J Schlessinger. Cytokine Growth Factor Rev 2005
V P Eswarakumar, I Lax, J Schlessinger. Cytokine Growth Factor Rev 2005
14
Complementary antagonistic actions between C-type natriuretic peptide and the MAPK pathway through FGFR-3 in ATDC5 cells.
Ami Ozasa, Yasato Komatsu, Akihiro Yasoda, Masako Miura, Yoko Sakuma, Yuko Nakatsuru, Hiroshi Arai, Nobuyuki Itoh, Kazuwa Nakao. Bone 2005
Ami Ozasa, Yasato Komatsu, Akihiro Yasoda, Masako Miura, Yoko Sakuma, Yuko Nakatsuru, Hiroshi Arai, Nobuyuki Itoh, Kazuwa Nakao. Bone 2005
20
Snail blocks the cell cycle and confers resistance to cell death.
Sonia Vega, Aixa V Morales, Oscar H Ocaña, Francisco Valdés, Isabel Fabregat, M Angela Nieto. Genes Dev 2004
Sonia Vega, Aixa V Morales, Oscar H Ocaña, Francisco Valdés, Isabel Fabregat, M Angela Nieto. Genes Dev 2004
13
The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression.
A Cano, M A Pérez-Moreno, I Rodrigo, A Locascio, M J Blanco, M G del Barrio, F Portillo, M A Nieto. Nat Cell Biol 2000
A Cano, M A Pérez-Moreno, I Rodrigo, A Locascio, M J Blanco, M G del Barrio, F Portillo, M A Nieto. Nat Cell Biol 2000
13
Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation.
B St-Jacques, M Hammerschmidt, A P McMahon. Genes Dev 1999
B St-Jacques, M Hammerschmidt, A P McMahon. Genes Dev 1999
13
Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth.
Kai Yu, Jingsong Xu, Zhonghao Liu, Drazen Sosic, Jiansu Shao, Eric N Olson, Dwight A Towler, David M Ornitz. Development 2003
Kai Yu, Jingsong Xu, Zhonghao Liu, Drazen Sosic, Jiansu Shao, Eric N Olson, Dwight A Towler, David M Ornitz. Development 2003
13
Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation.
Anne L Jacob, Craig Smith, Juha Partanen, David M Ornitz. Dev Biol 2006
Anne L Jacob, Craig Smith, Juha Partanen, David M Ornitz. Dev Biol 2006
13
Defective lysosomal targeting of activated fibroblast growth factor receptor 3 in achondroplasia.
Jay Y Cho, Changsheng Guo, Monica Torello, Gregory P Lunstrum, Tomoko Iwata, Chuxia Deng, William A Horton. Proc Natl Acad Sci U S A 2004
Jay Y Cho, Changsheng Guo, Monica Torello, Gregory P Lunstrum, Tomoko Iwata, Chuxia Deng, William A Horton. Proc Natl Acad Sci U S A 2004
13
Activation of the ERK1/2 and p38 mitogen-activated protein kinase pathways mediates fibroblast growth factor-induced growth arrest of chondrocytes.
Angela Raucci, Emmanuel Laplantine, Alka Mansukhani, Claudio Basilico. J Biol Chem 2004
Angela Raucci, Emmanuel Laplantine, Alka Mansukhani, Claudio Basilico. J Biol Chem 2004
13
Systemic administration of C-type natriuretic peptide as a novel therapeutic strategy for skeletal dysplasias.
Akihiro Yasoda, Hidetomo Kitamura, Toshihito Fujii, Eri Kondo, Naoaki Murao, Masako Miura, Naotetsu Kanamoto, Yasato Komatsu, Hiroshi Arai, Kazuwa Nakao. Endocrinology 2009
Akihiro Yasoda, Hidetomo Kitamura, Toshihito Fujii, Eri Kondo, Naoaki Murao, Masako Miura, Naotetsu Kanamoto, Yasato Komatsu, Hiroshi Arai, Kazuwa Nakao. Endocrinology 2009
13
The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6.
Haruhiko Akiyama, Marie-Christine Chaboissier, James F Martin, Andreas Schedl, Benoit de Crombrugghe. Genes Dev 2002
Haruhiko Akiyama, Marie-Christine Chaboissier, James F Martin, Andreas Schedl, Benoit de Crombrugghe. Genes Dev 2002
13
Sox9 is required for cartilage formation.
W Bi, J M Deng, Z Zhang, R R Behringer, B de Crombrugghe. Nat Genet 1999
W Bi, J M Deng, Z Zhang, R R Behringer, B de Crombrugghe. Nat Genet 1999
13
Graded activation of fibroblast growth factor receptor 3 by mutations causing achondroplasia and thanatophoric dysplasia.
M C Naski, Q Wang, J Xu, D M Ornitz. Nat Genet 1996
M C Naski, Q Wang, J Xu, D M Ornitz. Nat Genet 1996
13
Highly activated Fgfr3 with the K644M mutation causes prolonged survival in severe dwarf mice.
T Iwata, C L Li, C X Deng, C A Francomano. Hum Mol Genet 2001
T Iwata, C L Li, C X Deng, C A Francomano. Hum Mol Genet 2001
13
A novel mutation in FGFR3 causes camptodactyly, tall stature, and hearing loss (CATSHL) syndrome.
Reha M Toydemir, Anna E Brassington, Pinar Bayrak-Toydemir, Patrycja A Krakowiak, Lynn B Jorde, Frank G Whitby, Nicola Longo, David H Viskochil, John C Carey, Michael J Bamshad. Am J Hum Genet 2006
Reha M Toydemir, Anna E Brassington, Pinar Bayrak-Toydemir, Patrycja A Krakowiak, Lynn B Jorde, Frank G Whitby, Nicola Longo, David H Viskochil, John C Carey, Michael J Bamshad. Am J Hum Genet 2006
13
Postnatal soluble FGFR3 therapy rescues achondroplasia symptoms and restores bone growth in mice.
Stéphanie Garcia, Béatrice Dirat, Thomas Tognacci, Nathalie Rochet, Xavier Mouska, Stéphanie Bonnafous, Stéphanie Patouraux, Albert Tran, Philippe Gual, Yannick Le Marchand-Brustel,[...]. Sci Transl Med 2013
Stéphanie Garcia, Béatrice Dirat, Thomas Tognacci, Nathalie Rochet, Xavier Mouska, Stéphanie Bonnafous, Stéphanie Patouraux, Albert Tran, Philippe Gual, Yannick Le Marchand-Brustel,[...]. Sci Transl Med 2013
15
Evaluation of the therapeutic potential of a CNP analog in a Fgfr3 mouse model recapitulating achondroplasia.
Florence Lorget, Nabil Kaci, Jeff Peng, Catherine Benoist-Lasselin, Emilie Mugniery, Todd Oppeneer, Dan J Wendt, Sean M Bell, Sherry Bullens, Stuart Bunting,[...]. Am J Hum Genet 2012
Florence Lorget, Nabil Kaci, Jeff Peng, Catherine Benoist-Lasselin, Emilie Mugniery, Todd Oppeneer, Dan J Wendt, Sean M Bell, Sherry Bullens, Stuart Bunting,[...]. Am J Hum Genet 2012
13
A pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturation.
Elena Kozhemyakina, Andrew B Lassar, Elazar Zelzer. Development 2015
Elena Kozhemyakina, Andrew B Lassar, Elazar Zelzer. Development 2015
13
Fibroblast growth factor expression in the postnatal growth plate.
Jacob E Lazarus, Anita Hegde, Anenisia C Andrade, Ola Nilsson, Jeffrey Baron. Bone 2007
Jacob E Lazarus, Anita Hegde, Anenisia C Andrade, Ola Nilsson, Jeffrey Baron. Bone 2007
11
Mechanisms underlying differential responses to FGF signaling.
Lisa Dailey, Davide Ambrosetti, Alka Mansukhani, Claudio Basilico. Cytokine Growth Factor Rev 2005
Lisa Dailey, Davide Ambrosetti, Alka Mansukhani, Claudio Basilico. Cytokine Growth Factor Rev 2005
11
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.