M M Fraser, I T Bayazitov, S S Zakharenko, S J Baker. Neuroscience 2008
Times Cited: 140
Times Cited: 140
Times Cited
Times Co-cited
Similarity
Pten regulates neuronal arborization and social interaction in mice.
Chang-Hyuk Kwon, Bryan W Luikart, Craig M Powell, Jing Zhou, Sharon A Matheny, Wei Zhang, Yanjiao Li, Suzanne J Baker, Luis F Parada. Neuron 2006
Chang-Hyuk Kwon, Bryan W Luikart, Craig M Powell, Jing Zhou, Sharon A Matheny, Wei Zhang, Yanjiao Li, Suzanne J Baker, Luis F Parada. Neuron 2006
54
Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations.
M G Butler, M J Dasouki, X-P Zhou, Z Talebizadeh, M Brown, T N Takahashi, J H Miles, C H Wang, R Stratton, R Pilarski,[...]. J Med Genet 2005
M G Butler, M J Dasouki, X-P Zhou, Z Talebizadeh, M Brown, T N Takahashi, J H Miles, C H Wang, R Stratton, R Pilarski,[...]. J Med Genet 2005
40
Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease.
S A Backman, V Stambolic, A Suzuki, J Haight, A Elia, J Pretorius, M S Tsao, P Shannon, B Bolon, G O Ivy,[...]. Nat Genet 2001
S A Backman, V Stambolic, A Suzuki, J Haight, A Elia, J Pretorius, M S Tsao, P Shannon, B Bolon, G O Ivy,[...]. Nat Genet 2001
31
Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice.
Jing Zhou, Jacqueline Blundell, Shiori Ogawa, Chang-Hyuk Kwon, Wei Zhang, Christopher Sinton, Craig M Powell, Luis F Parada. J Neurosci 2009
Jing Zhou, Jacqueline Blundell, Shiori Ogawa, Chang-Hyuk Kwon, Wei Zhang, Christopher Sinton, Craig M Powell, Luis F Parada. J Neurosci 2009
29
Phosphatase and tensin homologue (PTEN) regulates synaptic plasticity independently of its effect on neuronal morphology and migration.
Margaret Sperow, Raymond B Berry, Ildar T Bayazitov, Guo Zhu, Suzanne J Baker, Stanislav S Zakharenko. J Physiol 2012
Margaret Sperow, Raymond B Berry, Ildar T Bayazitov, Guo Zhu, Suzanne J Baker, Stanislav S Zakharenko. J Physiol 2012
39
Pten knockdown in vivo increases excitatory drive onto dentate granule cells.
Bryan W Luikart, Eric Schnell, Eric K Washburn, Aesoon L Bensen, Kenneth R Tovar, Gary L Westbrook. J Neurosci 2011
Bryan W Luikart, Eric Schnell, Eric K Washburn, Aesoon L Bensen, Kenneth R Tovar, Gary L Westbrook. J Neurosci 2011
27
Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease.
C H Kwon, X Zhu, J Zhang, L L Knoop, R Tharp, R J Smeyne, C G Eberhart, P C Burger, S J Baker. Nat Genet 2001
C H Kwon, X Zhu, J Zhang, L L Knoop, R Tharp, R J Smeyne, C G Eberhart, P C Burger, S J Baker. Nat Genet 2001
26
Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism.
Koichi Takeuchi, Michael J Gertner, Jing Zhou, Luis F Parada, Michael V L Bennett, R Suzanne Zukin. Proc Natl Acad Sci U S A 2013
Koichi Takeuchi, Michael J Gertner, Jing Zhou, Luis F Parada, Michael V L Bennett, R Suzanne Zukin. Proc Natl Acad Sci U S A 2013
31
Mutation screening of the PTEN gene in patients with autism spectrum disorders and macrocephaly.
Joseph D Buxbaum, Guiqing Cai, Pauline Chaste, Gudrun Nygren, Juliet Goldsmith, Jennifer Reichert, Henrik Anckarsäter, Maria Rastam, Christopher J Smith, Jeremy M Silverman,[...]. Am J Med Genet B Neuropsychiatr Genet 2007
Joseph D Buxbaum, Guiqing Cai, Pauline Chaste, Gudrun Nygren, Juliet Goldsmith, Jennifer Reichert, Henrik Anckarsäter, Maria Rastam, Christopher J Smith, Jeremy M Silverman,[...]. Am J Med Genet B Neuropsychiatr Genet 2007
21
Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo.
M Groszer, R Erickson, D D Scripture-Adams, R Lesche, A Trumpp, J A Zack, H I Kornblum, X Liu, H Wu. Science 2001
M Groszer, R Erickson, D D Scripture-Adams, R Lesche, A Trumpp, J A Zack, H I Kornblum, X Liu, H Wu. Science 2001
21
The prevalence of PTEN mutations in a clinical pediatric cohort with autism spectrum disorders, developmental delay, and macrocephaly.
Elizabeth A Varga, Matthew Pastore, Thomas Prior, Gail E Herman, Kim L McBride. Genet Med 2009
Elizabeth A Varga, Matthew Pastore, Thomas Prior, Gail E Herman, Kim L McBride. Genet Med 2009
19
Control of dendritic arborization by the phosphoinositide-3'-kinase-Akt-mammalian target of rapamycin pathway.
Jacek Jaworski, Samantha Spangler, Daniel P Seeburg, Casper C Hoogenraad, Morgan Sheng. J Neurosci 2005
Jacek Jaworski, Samantha Spangler, Daniel P Seeburg, Casper C Hoogenraad, Morgan Sheng. J Neurosci 2005
19
PTEN is recruited to the postsynaptic terminal for NMDA receptor-dependent long-term depression.
Sandra Jurado, Marion Benoist, Argentina Lario, Shira Knafo, Cortney N Petrok, José A Esteban. EMBO J 2010
Sandra Jurado, Marion Benoist, Argentina Lario, Shira Knafo, Cortney N Petrok, José A Esteban. EMBO J 2010
19
Confirmation study of PTEN mutations among individuals with autism or developmental delays/mental retardation and macrocephaly.
Kim L McBride, Elizabeth A Varga, Matthew T Pastore, Thomas W Prior, Kandamurugu Manickam, Joan F Atkin, Gail E Herman. Autism Res 2010
Kim L McBride, Elizabeth A Varga, Matthew T Pastore, Thomas W Prior, Kandamurugu Manickam, Joan F Atkin, Gail E Herman. Autism Res 2010
19
Multiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disorders.
Brian J O'Roak, Laura Vives, Wenqing Fu, Jarrett D Egertson, Ian B Stanaway, Ian G Phelps, Gemma Carvill, Akash Kumar, Choli Lee, Katy Ankenman,[...]. Science 2012
Brian J O'Roak, Laura Vives, Wenqing Fu, Jarrett D Egertson, Ian B Stanaway, Ian G Phelps, Gemma Carvill, Akash Kumar, Choli Lee, Katy Ankenman,[...]. Science 2012
18
Excessive activation of mTOR in postnatally generated granule cells is sufficient to cause epilepsy.
Raymund Y K Pun, Isaiah J Rolle, Candi L Lasarge, Bethany E Hosford, Jules M Rosen, Juli D Uhl, Sarah N Schmeltzer, Christian Faulkner, Stefanie L Bronson, Brian L Murphy,[...]. Neuron 2012
Raymund Y K Pun, Isaiah J Rolle, Candi L Lasarge, Bethany E Hosford, Jules M Rosen, Juli D Uhl, Sarah N Schmeltzer, Christian Faulkner, Stefanie L Bronson, Brian L Murphy,[...]. Neuron 2012
17
PTEN mutation in a family with Cowden syndrome and autism.
A Goffin, L H Hoefsloot, E Bosgoed, A Swillen, J P Fryns. Am J Med Genet 2001
A Goffin, L H Hoefsloot, E Bosgoed, A Swillen, J P Fryns. Am J Med Genet 2001
16
16
Pten deletion in adult hippocampal neural stem/progenitor cells causes cellular abnormalities and alters neurogenesis.
Anahita Amiri, Woosung Cho, Jing Zhou, Shari G Birnbaum, Christopher M Sinton, Renée M McKay, Luis F Parada. J Neurosci 2012
Anahita Amiri, Woosung Cho, Jing Zhou, Shari G Birnbaum, Christopher M Sinton, Renée M McKay, Luis F Parada. J Neurosci 2012
16
PTEN knockdown alters dendritic spine/protrusion morphology, not density.
Michael E Haws, Thomas C Jaramillo, Felipe Espinosa, Allie J Widman, Garret D Stuber, Dennis R Sparta, Kay M Tye, Scott J Russo, Luis F Parada, Mihaela Stavarache,[...]. J Comp Neurol 2014
Michael E Haws, Thomas C Jaramillo, Felipe Espinosa, Allie J Widman, Garret D Stuber, Dennis R Sparta, Kay M Tye, Scott J Russo, Luis F Parada, Mihaela Stavarache,[...]. J Comp Neurol 2014
41
Hyperactivity of newborn Pten knock-out neurons results from increased excitatory synaptic drive.
Michael R Williams, Tyrone DeSpenza, Meijie Li, Allan T Gulledge, Bryan W Luikart. J Neurosci 2015
Michael R Williams, Tyrone DeSpenza, Meijie Li, Allan T Gulledge, Bryan W Luikart. J Neurosci 2015
22
Synaptic, transcriptional and chromatin genes disrupted in autism.
Silvia De Rubeis, Xin He, Arthur P Goldberg, Christopher S Poultney, Kaitlin Samocha, A Erucment Cicek, Yan Kou, Li Liu, Menachem Fromer, Susan Walker,[...]. Nature 2014
Silvia De Rubeis, Xin He, Arthur P Goldberg, Christopher S Poultney, Kaitlin Samocha, A Erucment Cicek, Yan Kou, Li Liu, Menachem Fromer, Susan Walker,[...]. Nature 2014
16
The PTEN phosphatase is essential for long-term depression of hippocampal synapses.
Yue Wang, Aiwu Cheng, Mark P Mattson. Neuromolecular Med 2006
Yue Wang, Aiwu Cheng, Mark P Mattson. Neuromolecular Med 2006
38
Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2.
Sohail F Tavazoie, Veronica A Alvarez, Dennis A Ridenour, David J Kwiatkowski, Bernardo L Sabatini. Nat Neurosci 2005
Sohail F Tavazoie, Veronica A Alvarez, Dennis A Ridenour, David J Kwiatkowski, Bernardo L Sabatini. Nat Neurosci 2005
15
Mutations causing syndromic autism define an axis of synaptic pathophysiology.
Benjamin D Auerbach, Emily K Osterweil, Mark F Bear. Nature 2011
Benjamin D Auerbach, Emily K Osterweil, Mark F Bear. Nature 2011
14
PTEN is essential for cell migration but not for fate determination and tumourigenesis in the cerebellum.
Silvia Marino, Paul Krimpenfort, Carly Leung, Hetty A G M van der Korput, Jan Trapman, Isabelle Camenisch, Anton Berns, Sebastian Brandner. Development 2002
Silvia Marino, Paul Krimpenfort, Carly Leung, Hetty A G M van der Korput, Jan Trapman, Isabelle Camenisch, Anton Berns, Sebastian Brandner. Development 2002
14
Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway.
Kevin Kyungsuk Park, Kai Liu, Yang Hu, Patrice D Smith, Chen Wang, Bin Cai, Bengang Xu, Lauren Connolly, Ioannis Kramvis, Mustafa Sahin,[...]. Science 2008
Kevin Kyungsuk Park, Kai Liu, Yang Hu, Patrice D Smith, Chen Wang, Bin Cai, Bengang Xu, Lauren Connolly, Ioannis Kramvis, Mustafa Sahin,[...]. Science 2008
14
Pten loss causes hypertrophy and increased proliferation of astrocytes in vivo.
Melissa M Fraser, Xiaoyan Zhu, Chang-Hyuk Kwon, Erik J Uhlmann, David H Gutmann, Suzanne J Baker. Cancer Res 2004
Melissa M Fraser, Xiaoyan Zhu, Chang-Hyuk Kwon, Erik J Uhlmann, David H Gutmann, Suzanne J Baker. Cancer Res 2004
14
Loss of Tsc1 in vivo impairs hippocampal mGluR-LTD and increases excitatory synaptic function.
Helen S Bateup, Kevin T Takasaki, Jessica L Saulnier, Cassandra L Denefrio, Bernardo L Sabatini. J Neurosci 2011
Helen S Bateup, Kevin T Takasaki, Jessica L Saulnier, Cassandra L Denefrio, Bernardo L Sabatini. J Neurosci 2011
13
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate.
T Maehama, J E Dixon. J Biol Chem 1998
T Maehama, J E Dixon. J Biol Chem 1998
13
Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations.
Brian J O'Roak, Laura Vives, Santhosh Girirajan, Emre Karakoc, Niklas Krumm, Bradley P Coe, Roie Levy, Arthur Ko, Choli Lee, Joshua D Smith,[...]. Nature 2012
Brian J O'Roak, Laura Vives, Santhosh Girirajan, Emre Karakoc, Niklas Krumm, Bradley P Coe, Roie Levy, Arthur Ko, Choli Lee, Joshua D Smith,[...]. Nature 2012
12
A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice.
Katsuhiko Tabuchi, Jacqueline Blundell, Mark R Etherton, Robert E Hammer, Xinran Liu, Craig M Powell, Thomas C Südhof. Science 2007
Katsuhiko Tabuchi, Jacqueline Blundell, Mark R Etherton, Robert E Hammer, Xinran Liu, Craig M Powell, Thomas C Südhof. Science 2007
12
A comprehensive functional analysis of PTEN mutations: implications in tumor- and autism-related syndromes.
Isabel Rodríguez-Escudero, María D Oliver, Amparo Andrés-Pons, María Molina, Víctor J Cid, Rafael Pulido. Hum Mol Genet 2011
Isabel Rodríguez-Escudero, María D Oliver, Amparo Andrés-Pons, María Molina, Víctor J Cid, Rafael Pulido. Hum Mol Genet 2011
12
Molecular and phenotypic abnormalities in individuals with germline heterozygous PTEN mutations and autism.
T W Frazier, R Embacher, A K Tilot, K Koenig, J Mester, C Eng. Mol Psychiatry 2015
T W Frazier, R Embacher, A K Tilot, K Koenig, J Mester, C Eng. Mol Psychiatry 2015
12
Pten haploinsufficient mice show broad brain overgrowth but selective impairments in autism-relevant behavioral tests.
Amy E Clipperton-Allen, Damon T Page. Hum Mol Genet 2014
Amy E Clipperton-Allen, Damon T Page. Hum Mol Genet 2014
18
Shank3 mutant mice display autistic-like behaviours and striatal dysfunction.
João Peça, Cátia Feliciano, Jonathan T Ting, Wenting Wang, Michael F Wells, Talaignair N Venkatraman, Christopher D Lascola, Zhanyan Fu, Guoping Feng. Nature 2011
João Peça, Cátia Feliciano, Jonathan T Ting, Wenting Wang, Michael F Wells, Talaignair N Venkatraman, Christopher D Lascola, Zhanyan Fu, Guoping Feng. Nature 2011
11
Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis.
Dan Ehninger, Sangyeul Han, Carrie Shilyansky, Yu Zhou, Weidong Li, David J Kwiatkowski, Vijaya Ramesh, Alcino J Silva. Nat Med 2008
Dan Ehninger, Sangyeul Han, Carrie Shilyansky, Yu Zhou, Weidong Li, David J Kwiatkowski, Vijaya Ramesh, Alcino J Silva. Nat Med 2008
11
PTEN regulation of local and long-range connections in mouse auditory cortex.
Qiaojie Xiong, Hysell V Oviedo, Lloyd C Trotman, Anthony M Zador. J Neurosci 2012
Qiaojie Xiong, Hysell V Oviedo, Lloyd C Trotman, Anthony M Zador. J Neurosci 2012
29
PTEN deletion in Bergmann glia leads to premature differentiation and affects laminar organization.
Qing Yue, Matthias Groszer, Jose S Gil, Arnold J Berk, Albee Messing, Hong Wu, Xin Liu. Development 2005
Qing Yue, Matthias Groszer, Jose S Gil, Arnold J Berk, Albee Messing, Hong Wu, Xin Liu. Development 2005
13
Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination.
Sandra Goebbels, Jan H Oltrogge, Robert Kemper, Ingo Heilmann, Ingo Bormuth, Susanne Wolfer, Sven P Wichert, Wiebke Möbius, Xin Liu, Corinna Lappe-Siefke,[...]. J Neurosci 2010
Sandra Goebbels, Jan H Oltrogge, Robert Kemper, Ingo Heilmann, Ingo Bormuth, Susanne Wolfer, Sven P Wichert, Wiebke Möbius, Xin Liu, Corinna Lappe-Siefke,[...]. J Neurosci 2010
11
A seizure-prone phenotype is associated with altered free-running rhythm in Pten mutant mice.
Shiori Ogawa, Chang-Hyuk Kwon, Jing Zhou, Della Koovakkattu, Luis F Parada, Christopher M Sinton. Brain Res 2007
Shiori Ogawa, Chang-Hyuk Kwon, Jing Zhou, Della Koovakkattu, Luis F Parada, Christopher M Sinton. Brain Res 2007
19
Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice.
Peter T Tsai, Court Hull, YunXiang Chu, Emily Greene-Colozzi, Abbey R Sadowski, Jarrett M Leech, Jason Steinberg, Jacqueline N Crawley, Wade G Regehr, Mustafa Sahin. Nature 2012
Peter T Tsai, Court Hull, YunXiang Chu, Emily Greene-Colozzi, Abbey R Sadowski, Jarrett M Leech, Jason Steinberg, Jacqueline N Crawley, Wade G Regehr, Mustafa Sahin. Nature 2012
11
Deletion of PTEN produces autism-like behavioral deficits and alterations in synaptic proteins.
Joaquin N Lugo, Gregory D Smith, Erin P Arbuckle, Jessika White, Andrew J Holley, Crina M Floruta, Nowrin Ahmed, Maribel C Gomez, Obi Okonkwo. Front Mol Neurosci 2014
Joaquin N Lugo, Gregory D Smith, Erin P Arbuckle, Jessika White, Andrew J Holley, Crina M Floruta, Nowrin Ahmed, Maribel C Gomez, Obi Okonkwo. Front Mol Neurosci 2014
11
Increasing knowledge of PTEN germline mutations: Two additional patients with autism and macrocephaly.
Gail E Herman, Eric Butter, Benedicta Enrile, Matthew Pastore, Thomas W Prior, Annemarie Sommer. Am J Med Genet A 2007
Gail E Herman, Eric Butter, Benedicta Enrile, Matthew Pastore, Thomas W Prior, Annemarie Sommer. Am J Med Genet A 2007
10
Dysregulation of mTOR signaling in fragile X syndrome.
Ali Sharma, Charles A Hoeffer, Yukihiro Takayasu, Takahiro Miyawaki, Sean M McBride, Eric Klann, R Suzanne Zukin. J Neurosci 2010
Ali Sharma, Charles A Hoeffer, Yukihiro Takayasu, Takahiro Miyawaki, Sean M McBride, Eric Klann, R Suzanne Zukin. J Neurosci 2010
10
Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism.
Stéphane Jamain, Hélène Quach, Catalina Betancur, Maria Råstam, Catherine Colineaux, I Carina Gillberg, Henrik Soderstrom, Bruno Giros, Marion Leboyer, Christopher Gillberg,[...]. Nat Genet 2003
Stéphane Jamain, Hélène Quach, Catalina Betancur, Maria Råstam, Catherine Colineaux, I Carina Gillberg, Henrik Soderstrom, Bruno Giros, Marion Leboyer, Christopher Gillberg,[...]. Nat Genet 2003
10
De novo mutations revealed by whole-exome sequencing are strongly associated with autism.
Stephan J Sanders, Michael T Murtha, Abha R Gupta, John D Murdoch, Melanie J Raubeson, A Jeremy Willsey, A Gulhan Ercan-Sencicek, Nicholas M DiLullo, Neelroop N Parikshak, Jason L Stein,[...]. Nature 2012
Stephan J Sanders, Michael T Murtha, Abha R Gupta, John D Murdoch, Melanie J Raubeson, A Jeremy Willsey, A Gulhan Ercan-Sencicek, Nicholas M DiLullo, Neelroop N Parikshak, Jason L Stein,[...]. Nature 2012
10
Pten is essential for embryonic development and tumour suppression.
A Di Cristofano, B Pesce, C Cordon-Cardo, P P Pandolfi. Nat Genet 1998
A Di Cristofano, B Pesce, C Cordon-Cardo, P P Pandolfi. Nat Genet 1998
10
Novel PTEN mutations in neurodevelopmental disorders and macrocephaly.
A Orrico, L Galli, S Buoni, A Orsi, G Vonella, V Sorrentino. Clin Genet 2009
A Orrico, L Galli, S Buoni, A Orsi, G Vonella, V Sorrentino. Clin Genet 2009
12
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.