A citation-based method for searching scientific literature

Gül Dölen, Emily Osterweil, B S Shankaranarayana Rao, Gordon B Smith, Benjamin D Auerbach, Sumantra Chattarji, Mark F Bear. Neuron 2007
Times Cited: 681







List of co-cited articles
1430 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


The mGluR theory of fragile X mental retardation.
Mark F Bear, Kimberly M Huber, Stephen T Warren. Trends Neurosci 2004
39

Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice.
Aubin Michalon, Michael Sidorov, Theresa M Ballard, Laurence Ozmen, Will Spooren, Joseph G Wettstein, Georg Jaeschke, Mark F Bear, Lothar Lindemann. Neuron 2012
343
37

FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism.
Jennifer C Darnell, Sarah J Van Driesche, Chaolin Zhang, Ka Ying Sharon Hung, Aldo Mele, Claire E Fraser, Elizabeth F Stone, Cynthia Chen, John J Fak, Sung Wook Chi,[...]. Cell 2011
35

Altered synaptic plasticity in a mouse model of fragile X mental retardation.
Kimberly M Huber, Sean M Gallagher, Stephen T Warren, Mark F Bear. Proc Natl Acad Sci U S A 2002
952
34


Altered Neuronal and Circuit Excitability in Fragile X Syndrome.
Anis Contractor, Vitaly A Klyachko, Carlos Portera-Cailliau. Neuron 2015
193
21

Lovastatin corrects excess protein synthesis and prevents epileptogenesis in a mouse model of fragile X syndrome.
Emily K Osterweil, Shih-Chieh Chuang, Alexander A Chubykin, Michael Sidorov, Riccardo Bianchi, Robert K S Wong, Mark F Bear. Neuron 2013
147
20

Drug development for neurodevelopmental disorders: lessons learned from fragile X syndrome.
Elizabeth M Berry-Kravis, Lothar Lindemann, Aia E Jønch, George Apostol, Mark F Bear, Randall L Carpenter, Jacqueline N Crawley, Aurore Curie, Vincent Des Portes, Farah Hossain,[...]. Nat Rev Drug Discov 2018
135
19

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome.
A J Verkerk, M Pieretti, J S Sutcliffe, Y H Fu, D P Kuhl, A Pizzuti, O Reiner, S Richards, M F Victoria, F P Zhang. Cell 1991
18

Fragile X syndrome.
Randi J Hagerman, Elizabeth Berry-Kravis, Heather Cody Hazlett, Donald B Bailey, Herve Moine, R Frank Kooy, Flora Tassone, Ilse Gantois, Nahum Sonenberg, Jean Louis Mandel,[...]. Nat Rev Dis Primers 2017
192
18

Dysregulation and restoration of translational homeostasis in fragile X syndrome.
Joel D Richter, Gary J Bassell, Eric Klann. Nat Rev Neurosci 2015
146
18

Dysregulation of mTOR signaling in fragile X syndrome.
Ali Sharma, Charles A Hoeffer, Yukihiro Takayasu, Takahiro Miyawaki, Sean M McBride, Eric Klann, R Suzanne Zukin. J Neurosci 2010
393
17


Postadolescent changes in regional cerebral protein synthesis: an in vivo study in the FMR1 null mouse.
Mei Qin, Julia Kang, Thomas V Burlin, Chunhui Jiang, Carolyn Beebe Smith. J Neurosci 2005
168
16

Critical period plasticity is disrupted in the barrel cortex of FMR1 knockout mice.
Emily G Harlow, Sally M Till, Theron A Russell, Lasani S Wijetunge, Peter Kind, Anis Contractor. Neuron 2010
170
16

Reversal of disease-related pathologies in the fragile X mouse model by selective activation of GABAB receptors with arbaclofen.
Christina Henderson, Lasani Wijetunge, Mika Nakamoto Kinoshita, Matthew Shumway, Rebecca S Hammond, Friso R Postma, Christopher Brynczka, Roger Rush, Alexia Thomas, Richard Paylor,[...]. Sci Transl Med 2012
166
15

Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP.
Q J Yan, M Rammal, M Tranfaglia, R P Bauchwitz. Neuropharmacology 2005
383
15

Mavoglurant in fragile X syndrome: Results of two randomized, double-blind, placebo-controlled trials.
Elizabeth Berry-Kravis, Vincent Des Portes, Randi Hagerman, Sébastien Jacquemont, Perrine Charles, Jeannie Visootsak, Marc Brinkman, Karin Rerat, Barbara Koumaras, Liansheng Zhu,[...]. Sci Transl Med 2016
145
14

FMRP regulates neurotransmitter release and synaptic information transmission by modulating action potential duration via BK channels.
Pan-Yue Deng, Ziv Rotman, Jay A Blundon, Yongcheol Cho, Jianmin Cui, Valeria Cavalli, Stanislav S Zakharenko, Vitaly A Klyachko. Neuron 2013
201
14



The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP.
Ilaria Napoli, Valentina Mercaldo, Pietro Pilo Boyl, Boris Eleuteri, Francesca Zalfa, Silvia De Rubeis, Daniele Di Marino, Evita Mohr, Marzia Massimi, Mattia Falconi,[...]. Cell 2008
391
13

Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome.
V Brown, P Jin, S Ceman, J C Darnell, W T O'Donnell, S A Tenenbaum, X Jin, Y Feng, K D Wilkinson, J D Keene,[...]. Cell 2001
845
13

Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack.
Maile R Brown, Jack Kronengold, Valeswara-Rao Gazula, Yi Chen, John G Strumbos, Fred J Sigworth, Dhasakumar Navaratnam, Leonard K Kaczmarek. Nat Neurosci 2010
153
13

Molecular mechanisms of fragile X syndrome: a twenty-year perspective.
Michael R Santoro, Steven M Bray, Stephen T Warren. Annu Rev Pathol 2012
340
13

Metformin ameliorates core deficits in a mouse model of fragile X syndrome.
Ilse Gantois, Arkady Khoutorsky, Jelena Popic, Argel Aguilar-Valles, Erika Freemantle, Ruifeng Cao, Vijendra Sharma, Tine Pooters, Anmol Nagpal, Agnieszka Skalecka,[...]. Nat Med 2017
92
14

FMRP targets distinct mRNA sequence elements to regulate protein expression.
Manuel Ascano, Neelanjan Mukherjee, Pradeep Bandaru, Jason B Miller, Jeffrey D Nusbaum, David L Corcoran, Christine Langlois, Mathias Munschauer, Scott Dewell, Markus Hafner,[...]. Nature 2012
422
12

Fragile X targeted pharmacotherapy: lessons learned and future directions.
Craig A Erickson, Matthew H Davenport, Tori L Schaefer, Logan K Wink, Ernest V Pedapati, John A Sweeney, Sarah E Fitzpatrick, W Ted Brown, Dejan Budimirovic, Randi J Hagerman,[...]. J Neurodev Disord 2017
60
20

Genetic removal of p70 S6 kinase 1 corrects molecular, synaptic, and behavioral phenotypes in fragile X syndrome mice.
Aditi Bhattacharya, Hanoch Kaphzan, Amanda C Alvarez-Dieppa, Jaclyn P Murphy, Philippe Pierre, Eric Klann. Neuron 2012
204
12

Conserved hippocampal cellular pathophysiology but distinct behavioural deficits in a new rat model of FXS.
Sally M Till, Antonis Asiminas, Adam D Jackson, Danai Katsanevaki, Stephanie A Barnes, Emily K Osterweil, Mark F Bear, Sumantra Chattarji, Emma R Wood, David J A Wyllie,[...]. Hum Mol Genet 2015
53
22

Effect of the mGluR5-NAM Basimglurant on Behavior in Adolescents and Adults with Fragile X Syndrome in a Randomized, Double-Blind, Placebo-Controlled Trial: FragXis Phase 2 Results.
Eriene A Youssef, Elizabeth Berry-Kravis, Christian Czech, Randi J Hagerman, David Hessl, Chin Y Wong, Michael Rabbia, Dennis Deptula, Amy John, Russell Kinch,[...]. Neuropsychopharmacology 2018
60
18


Increased expression of the PI3K enhancer PIKE mediates deficits in synaptic plasticity and behavior in fragile X syndrome.
Christina Gross, Chia-Wei Chang, Seth M Kelly, Aditi Bhattacharya, Sean M J McBride, Scott W Danielson, Michael Q Jiang, Chi Bun Chan, Keqiang Ye, Jay R Gibson,[...]. Cell Rep 2015
65
16

Defective GABAergic neurotransmission and pharmacological rescue of neuronal hyperexcitability in the amygdala in a mouse model of fragile X syndrome.
Jose Luis Olmos-Serrano, Scott M Paluszkiewicz, Brandon S Martin, Walter E Kaufmann, Joshua G Corbin, Molly M Huntsman. J Neurosci 2010
213
10

Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile X syndrome.
Christina Gross, Mika Nakamoto, Xiaodi Yao, Chi-Bun Chan, So Y Yim, Keqiang Ye, Stephen T Warren, Gary J Bassell. J Neurosci 2010
182
10


Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function.
J C Darnell, K B Jensen, P Jin, V Brown, S T Warren, R B Darnell. Cell 2001
722
10


Impaired perceptual learning in a mouse model of Fragile X syndrome is mediated by parvalbumin neuron dysfunction and is reversible.
Anubhuti Goel, Daniel A Cantu, Janna Guilfoyle, Gunvant R Chaudhari, Aditi Newadkar, Barbara Todisco, Diego de Alba, Nazim Kourdougli, Lauren M Schmitt, Ernest Pedapati,[...]. Nat Neurosci 2018
55
18


Mutations causing syndromic autism define an axis of synaptic pathophysiology.
Benjamin D Auerbach, Emily K Osterweil, Mark F Bear. Nature 2011
413
10


Protein synthesis levels are increased in a subset of individuals with fragile X syndrome.
Sébastien Jacquemont, Laura Pacini, Aia E Jønch, Giulia Cencelli, Izabela Rozenberg, Yunsheng He, Laura D'Andrea, Giorgia Pedini, Marwa Eldeeb, Rob Willemsen,[...]. Hum Mol Genet 2018
25
40

Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486.
Bridget M Dolan, Sergio G Duron, David A Campbell, Benedikt Vollrath, B S Shankaranarayana Rao, Hui-Yeon Ko, Gregory G Lin, Arvind Govindarajan, Se-Young Choi, Susumu Tonegawa. Proc Natl Acad Sci U S A 2013
139
10

Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome.
Jennifer A Ronesi, Katie A Collins, Seth A Hays, Nien-Pei Tsai, Weirui Guo, Shari G Birnbaum, Jia-Hua Hu, Paul F Worley, Jay R Gibson, Kimberly M Huber. Nat Neurosci 2012
172
10


Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits.
T A Comery, J B Harris, P J Willems, B A Oostra, S A Irwin, I J Weiler, W T Greenough. Proc Natl Acad Sci U S A 1997
759
10

Effects of STX209 (arbaclofen) on neurobehavioral function in children and adults with fragile X syndrome: a randomized, controlled, phase 2 trial.
Elizabeth M Berry-Kravis, David Hessl, Barbara Rathmell, Peter Zarevics, Maryann Cherubini, Karen Walton-Bowen, Yi Mu, Danh V Nguyen, Joseph Gonzalez-Heydrich, Paul P Wang,[...]. Sci Transl Med 2012
217
9

Downregulation of tonic GABAergic inhibition in a mouse model of fragile X syndrome.
Giulia Curia, Thomas Papouin, Philippe Séguéla, Massimo Avoli. Cereb Cortex 2009
159
9



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.