Ann Cassidy-Stone, Jerry E Chipuk, Elena Ingerman, Cheng Song, Choong Yoo, Tomomi Kuwana, Mark J Kurth, Jared T Shaw, Jenny E Hinshaw, Douglas R Green, Jodi Nunnari. Dev Cell 2008
Times Cited: 762
Times Cited: 762
Times Cited
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The Putative Drp1 Inhibitor mdivi-1 Is a Reversible Mitochondrial Complex I Inhibitor that Modulates Reactive Oxygen Species.
Evan A Bordt, Pascaline Clerc, Brian A Roelofs, Andrew J Saladino, László Tretter, Vera Adam-Vizi, Edward Cherok, Ahmed Khalil, Nagendra Yadava, Shealinna X Ge,[...]. Dev Cell 2017
Evan A Bordt, Pascaline Clerc, Brian A Roelofs, Andrew J Saladino, László Tretter, Vera Adam-Vizi, Edward Cherok, Ahmed Khalil, Nagendra Yadava, Shealinna X Ge,[...]. Dev Cell 2017
39
Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission.
Oliver C Losón, Zhiyin Song, Hsiuchen Chen, David C Chan. Mol Biol Cell 2013
Oliver C Losón, Zhiyin Song, Hsiuchen Chen, David C Chan. Mol Biol Cell 2013
23
A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity.
Xin Qi, Nir Qvit, Yu-Chin Su, Daria Mochly-Rosen. J Cell Sci 2013
Xin Qi, Nir Qvit, Yu-Chin Su, Daria Mochly-Rosen. J Cell Sci 2013
21
Mitochondrial dynamics--mitochondrial fission and fusion in human diseases.
Stephen L Archer. N Engl J Med 2013
Stephen L Archer. N Engl J Med 2013
19
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy.
Gilad Twig, Alvaro Elorza, Anthony J A Molina, Hibo Mohamed, Jakob D Wikstrom, Gil Walzer, Linsey Stiles, Sarah E Haigh, Steve Katz, Guy Las,[...]. EMBO J 2008
Gilad Twig, Alvaro Elorza, Anthony J A Molina, Hibo Mohamed, Jakob D Wikstrom, Gil Walzer, Linsey Stiles, Sarah E Haigh, Steve Katz, Guy Las,[...]. EMBO J 2008
17
Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells.
E Smirnova, L Griparic, D L Shurland, A M van der Bliek. Mol Biol Cell 2001
E Smirnova, L Griparic, D L Shurland, A M van der Bliek. Mol Biol Cell 2001
17
Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission.
Naoko Taguchi, Naotada Ishihara, Akihiro Jofuku, Toshihiko Oka, Katsuyoshi Mihara. J Biol Chem 2007
Naoko Taguchi, Naotada Ishihara, Akihiro Jofuku, Toshihiko Oka, Katsuyoshi Mihara. J Biol Chem 2007
17
Mitochondrial dynamics: overview of molecular mechanisms.
Lisa Tilokani, Shun Nagashima, Vincent Paupe, Julien Prudent. Essays Biochem 2018
Lisa Tilokani, Shun Nagashima, Vincent Paupe, Julien Prudent. Essays Biochem 2018
15
Erk2 phosphorylation of Drp1 promotes mitochondrial fission and MAPK-driven tumor growth.
Jennifer A Kashatus, Aldo Nascimento, Lindsey J Myers, Annie Sher, Frances L Byrne, Kyle L Hoehn, Christopher M Counter, David F Kashatus. Mol Cell 2015
Jennifer A Kashatus, Aldo Nascimento, Lindsey J Myers, Annie Sher, Frances L Byrne, Kyle L Hoehn, Christopher M Counter, David F Kashatus. Mol Cell 2015
14
Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury.
Sang-Bing Ong, Sapna Subrayan, Shiang Y Lim, Derek M Yellon, Sean M Davidson, Derek J Hausenloy. Circulation 2010
Sang-Bing Ong, Sapna Subrayan, Shiang Y Lim, Derek M Yellon, Sean M Davidson, Derek J Hausenloy. Circulation 2010
13
The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis.
S Frank, B Gaume, E S Bergmann-Leitner, W W Leitner, E G Robert, F Catez, C L Smith, R J Youle. Dev Cell 2001
S Frank, B Gaume, E S Bergmann-Leitner, W W Leitner, E G Robert, F Catez, C L Smith, R J Youle. Dev Cell 2001
12
Mitochondrial division inhibitor 1 reduces dynamin-related protein 1 and mitochondrial fission activity.
Maria Manczak, Ramesh Kandimalla, Xiangling Yin, P Hemachandra Reddy. Hum Mol Genet 2019
Maria Manczak, Ramesh Kandimalla, Xiangling Yin, P Hemachandra Reddy. Hum Mol Genet 2019
18
To mdivi-1 or not to mdivi-1: Is that the question?
George Smith, Gianluca Gallo. Dev Neurobiol 2017
George Smith, Gianluca Gallo. Dev Neurobiol 2017
21
Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer.
Jalees Rehman, Hannah J Zhang, Peter T Toth, Yanmin Zhang, Glenn Marsboom, Zhigang Hong, Ravi Salgia, Aliya N Husain, Christian Wietholt, Stephen L Archer. FASEB J 2012
Jalees Rehman, Hannah J Zhang, Peter T Toth, Yanmin Zhang, Glenn Marsboom, Zhigang Hong, Ravi Salgia, Aliya N Husain, Christian Wietholt, Stephen L Archer. FASEB J 2012
12
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development.
Hsiuchen Chen, Scott A Detmer, Andrew J Ewald, Erik E Griffin, Scott E Fraser, David C Chan. J Cell Biol 2003
Hsiuchen Chen, Scott A Detmer, Andrew J Ewald, Erik E Griffin, Scott E Fraser, David C Chan. J Cell Biol 2003
11
PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria.
Yun Chen, Gerald W Dorn. Science 2013
Yun Chen, Gerald W Dorn. Science 2013
11
Metabolism. AMP-activated protein kinase mediates mitochondrial fission in response to energy stress.
Erin Quan Toyama, Sébastien Herzig, Julien Courchet, Tommy L Lewis, Oliver C Losón, Kristina Hellberg, Nathan P Young, Hsiuchen Chen, Franck Polleux, David C Chan,[...]. Science 2016
Erin Quan Toyama, Sébastien Herzig, Julien Courchet, Tommy L Lewis, Oliver C Losón, Kristina Hellberg, Nathan P Young, Hsiuchen Chen, Franck Polleux, David C Chan,[...]. Science 2016
11
Dynasore, a cell-permeable inhibitor of dynamin.
Eric Macia, Marcelo Ehrlich, Ramiro Massol, Emmanuel Boucrot, Christian Brunner, Tomas Kirchhausen. Dev Cell 2006
Eric Macia, Marcelo Ehrlich, Ramiro Massol, Emmanuel Boucrot, Christian Brunner, Tomas Kirchhausen. Dev Cell 2006
11
11
Mitochondrial control by DRP1 in brain tumor initiating cells.
Qi Xie, Qiulian Wu, Craig M Horbinski, William A Flavahan, Kailin Yang, Wenchao Zhou, Stephen M Dombrowski, Zhi Huang, Xiaoguang Fang, Yu Shi,[...]. Nat Neurosci 2015
Qi Xie, Qiulian Wu, Craig M Horbinski, William A Flavahan, Kailin Yang, Wenchao Zhou, Stephen M Dombrowski, Zhi Huang, Xiaoguang Fang, Yu Shi,[...]. Nat Neurosci 2015
11
ER tubules mark sites of mitochondrial division.
Jonathan R Friedman, Laura L Lackner, Matthew West, Jared R DiBenedetto, Jodi Nunnari, Gia K Voeltz. Science 2011
Jonathan R Friedman, Laura L Lackner, Matthew West, Jared R DiBenedetto, Jodi Nunnari, Gia K Voeltz. Science 2011
11
Mitochondrial dynamics and apoptosis.
Der-Fen Suen, Kristi L Norris, Richard J Youle. Genes Dev 2008
Der-Fen Suen, Kristi L Norris, Richard J Youle. Genes Dev 2008
10
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy.
Michael Lazarou, Danielle A Sliter, Lesley A Kane, Shireen A Sarraf, Chunxin Wang, Jonathon L Burman, Dionisia P Sideris, Adam I Fogel, Richard J Youle. Nature 2015
Michael Lazarou, Danielle A Sliter, Lesley A Kane, Shireen A Sarraf, Chunxin Wang, Jonathon L Burman, Dionisia P Sideris, Adam I Fogel, Richard J Youle. Nature 2015
10
Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension.
Glenn Marsboom, Peter T Toth, John J Ryan, Zhigang Hong, Xichen Wu, Yong-Hu Fang, Thenappan Thenappan, Lin Piao, Hannah J Zhang, Jennifer Pogoriler,[...]. Circ Res 2012
Glenn Marsboom, Peter T Toth, John J Ryan, Zhigang Hong, Xichen Wu, Yong-Hu Fang, Thenappan Thenappan, Lin Piao, Hannah J Zhang, Jennifer Pogoriler,[...]. Circ Res 2012
10
Mitochondrial Division Inhibitor 1 (mdivi-1) Protects Neurons against Excitotoxicity through the Modulation of Mitochondrial Function and Intracellular Ca2+ Signaling.
Asier Ruiz, Elena Alberdi, Carlos Matute. Front Mol Neurosci 2018
Asier Ruiz, Elena Alberdi, Carlos Matute. Front Mol Neurosci 2018
23
Mitochondrial dynamics regulates migration and invasion of breast cancer cells.
J Zhao, J Zhang, M Yu, Y Xie, Y Huang, D W Wolff, P W Abel, Y Tu. Oncogene 2013
J Zhao, J Zhang, M Yu, Y Xie, Y Huang, D W Wolff, P W Abel, Y Tu. Oncogene 2013
10
Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells.
Hidenori Otera, Chunxin Wang, Megan M Cleland, Kiyoko Setoguchi, Sadaki Yokota, Richard J Youle, Katsuyoshi Mihara. J Cell Biol 2010
Hidenori Otera, Chunxin Wang, Megan M Cleland, Kiyoko Setoguchi, Sadaki Yokota, Richard J Youle, Katsuyoshi Mihara. J Cell Biol 2010
9
Mitochondrial fission facilitates the selective mitophagy of protein aggregates.
Jonathon L Burman, Sarah Pickles, Chunxin Wang, Shiori Sekine, Jose Norberto S Vargas, Zhe Zhang, Alice M Youle, Catherine L Nezich, Xufeng Wu, John A Hammer,[...]. J Cell Biol 2017
Jonathon L Burman, Sarah Pickles, Chunxin Wang, Shiori Sekine, Jose Norberto S Vargas, Zhe Zhang, Alice M Youle, Catherine L Nezich, Xufeng Wu, John A Hammer,[...]. J Cell Biol 2017
9
Mitochondrial division is requisite to RAS-induced transformation and targeted by oncogenic MAPK pathway inhibitors.
Madhavika N Serasinghe, Shira Y Wieder, Thibaud T Renault, Rana Elkholi, James J Asciolla, Jonathon L Yao, Omar Jabado, Kyle Hoehn, Yusuke Kageyama, Hiromi Sesaki,[...]. Mol Cell 2015
Madhavika N Serasinghe, Shira Y Wieder, Thibaud T Renault, Rana Elkholi, James J Asciolla, Jonathon L Yao, Omar Jabado, Kyle Hoehn, Yusuke Kageyama, Hiromi Sesaki,[...]. Mol Cell 2015
9
Dynamin-related protein 1 (Drp1)-mediated diastolic dysfunction in myocardial ischemia-reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission.
Willard W Sharp, Yong Hu Fang, Mei Han, Hannah J Zhang, Zhigang Hong, Alexandra Banathy, Erik Morrow, John J Ryan, Stephen L Archer. FASEB J 2014
Willard W Sharp, Yong Hu Fang, Mei Han, Hannah J Zhang, Zhigang Hong, Alexandra Banathy, Erik Morrow, John J Ryan, Stephen L Archer. FASEB J 2014
9
The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells.
Shilpa Gandre-Babbe, Alexander M van der Bliek. Mol Biol Cell 2008
Shilpa Gandre-Babbe, Alexander M van der Bliek. Mol Biol Cell 2008
9
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease.
Xinglong Wang, Bo Su, Hyoung-gon Lee, Xinyi Li, George Perry, Mark A Smith, Xiongwei Zhu. J Neurosci 2009
Xinglong Wang, Bo Su, Hyoung-gon Lee, Xinyi Li, George Perry, Mark A Smith, Xiongwei Zhu. J Neurosci 2009
9
Dynamics of Dynamin-Related Protein 1 in Alzheimer's Disease and Other Neurodegenerative Diseases.
Darryll Oliver, P Hemachandra Reddy. Cells 2019
Darryll Oliver, P Hemachandra Reddy. Cells 2019
13
MiD49 and MiD51, new components of the mitochondrial fission machinery.
Catherine S Palmer, Laura D Osellame, David Laine, Olga S Koutsopoulos, Ann E Frazier, Michael T Ryan. EMBO Rep 2011
Catherine S Palmer, Laura D Osellame, David Laine, Olga S Koutsopoulos, Ann E Frazier, Michael T Ryan. EMBO Rep 2011
9
Fusion and fission: interlinked processes critical for mitochondrial health.
David C Chan. Annu Rev Genet 2012
David C Chan. Annu Rev Genet 2012
8
OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion.
Christian Frezza, Sara Cipolat, Olga Martins de Brito, Massimo Micaroni, Galina V Beznoussenko, Tomasz Rudka, Davide Bartoli, Roman S Polishuck, Nika N Danial, Bart De Strooper,[...]. Cell 2006
Christian Frezza, Sara Cipolat, Olga Martins de Brito, Massimo Micaroni, Galina V Beznoussenko, Tomasz Rudka, Davide Bartoli, Roman S Polishuck, Nika N Danial, Bart De Strooper,[...]. Cell 2006
8
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin.
Derek P Narendra, Seok Min Jin, Atsushi Tanaka, Der-Fen Suen, Clement A Gautier, Jie Shen, Mark R Cookson, Richard J Youle. PLoS Biol 2010
Derek P Narendra, Seok Min Jin, Atsushi Tanaka, Der-Fen Suen, Clement A Gautier, Jie Shen, Mark R Cookson, Richard J Youle. PLoS Biol 2010
8
Mitochondrial dynamics, mitophagy and cardiovascular disease.
César Vásquez-Trincado, Ivonne García-Carvajal, Christian Pennanen, Valentina Parra, Joseph A Hill, Beverly A Rothermel, Sergio Lavandero. J Physiol 2016
César Vásquez-Trincado, Ivonne García-Carvajal, Christian Pennanen, Valentina Parra, Joseph A Hill, Beverly A Rothermel, Sergio Lavandero. J Physiol 2016
8
During autophagy mitochondria elongate, are spared from degradation and sustain cell viability.
Ligia C Gomes, Giulietta Di Benedetto, Luca Scorrano. Nat Cell Biol 2011
Ligia C Gomes, Giulietta Di Benedetto, Luca Scorrano. Nat Cell Biol 2011
8
Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice.
Naotada Ishihara, Masatoshi Nomura, Akihiro Jofuku, Hiroki Kato, Satoshi O Suzuki, Keiji Masuda, Hidenori Otera, Yae Nakanishi, Ikuya Nonaka, Yu-Ichi Goto,[...]. Nat Cell Biol 2009
Naotada Ishihara, Masatoshi Nomura, Akihiro Jofuku, Hiroki Kato, Satoshi O Suzuki, Keiji Masuda, Hidenori Otera, Yae Nakanishi, Ikuya Nonaka, Yu-Ichi Goto,[...]. Nat Cell Biol 2009
8
Targeting Mitochondrial Fission Using Mdivi-1 in A Clinically Relevant Large Animal Model of Acute Myocardial Infarction: A Pilot Study.
Sang-Bing Ong, Xiu-Yi Kwek, Khairunnisa Katwadi, Sauri Hernandez-Resendiz, Gustavo E Crespo-Avilan, Nur Izzah Ismail, Ying-Hsi Lin, En Ping Yap, Song-Yi Lim, K P Myu Mai Ja,[...]. Int J Mol Sci 2019
Sang-Bing Ong, Xiu-Yi Kwek, Khairunnisa Katwadi, Sauri Hernandez-Resendiz, Gustavo E Crespo-Avilan, Nur Izzah Ismail, Ying-Hsi Lin, En Ping Yap, Song-Yi Lim, K P Myu Mai Ja,[...]. Int J Mol Sci 2019
25
A small molecule promotes mitochondrial fusion in mammalian cells.
Danling Wang, Jianing Wang, Ghislain M C Bonamy, Shelly Meeusen, Richard G Brusch, Carolina Turk, Pengyu Yang, Peter G Schultz. Angew Chem Int Ed Engl 2012
Danling Wang, Jianing Wang, Ghislain M C Bonamy, Shelly Meeusen, Richard G Brusch, Carolina Turk, Pengyu Yang, Peter G Schultz. Angew Chem Int Ed Engl 2012
10
Mitochondrial Dynamics and Metabolic Regulation.
Timothy Wai, Thomas Langer. Trends Endocrinol Metab 2016
Timothy Wai, Thomas Langer. Trends Endocrinol Metab 2016
8
Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming.
Michael D Buck, David O'Sullivan, Ramon I Klein Geltink, Jonathan D Curtis, Chih-Hao Chang, David E Sanin, Jing Qiu, Oliver Kretz, Daniel Braas, Gerritje J W van der Windt,[...]. Cell 2016
Michael D Buck, David O'Sullivan, Ramon I Klein Geltink, Jonathan D Curtis, Chih-Hao Chang, David E Sanin, Jing Qiu, Oliver Kretz, Daniel Braas, Gerritje J W van der Windt,[...]. Cell 2016
8
Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model.
Seung Hyun Baek, So Jung Park, Jae In Jeong, Sung Hyun Kim, Jihoon Han, Jae Won Kyung, Sang-Ha Baik, Yuri Choi, Bo Youn Choi, Jin Su Park,[...]. J Neurosci 2017
Seung Hyun Baek, So Jung Park, Jae In Jeong, Sung Hyun Kim, Jihoon Han, Jae Won Kyung, Sang-Ha Baik, Yuri Choi, Bo Youn Choi, Jin Su Park,[...]. J Neurosci 2017
8
Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species.
Tianzheng Yu, Shey-Shing Sheu, James L Robotham, Yisang Yoon. Cardiovasc Res 2008
Tianzheng Yu, Shey-Shing Sheu, James L Robotham, Yisang Yoon. Cardiovasc Res 2008
8
Endogenous Drp1 mediates mitochondrial autophagy and protects the heart against energy stress.
Yoshiyuki Ikeda, Akihiro Shirakabe, Yasuhiro Maejima, Peiyong Zhai, Sebastiano Sciarretta, Jessica Toli, Masatoshi Nomura, Katsuyoshi Mihara, Kensuke Egashira, Mitsuru Ohishi,[...]. Circ Res 2015
Yoshiyuki Ikeda, Akihiro Shirakabe, Yasuhiro Maejima, Peiyong Zhai, Sebastiano Sciarretta, Jessica Toli, Masatoshi Nomura, Katsuyoshi Mihara, Kensuke Egashira, Mitsuru Ohishi,[...]. Circ Res 2015
7
Membrane remodeling induced by the dynamin-related protein Drp1 stimulates Bax oligomerization.
Sylvie Montessuit, Syam Prakash Somasekharan, Oihana Terrones, Safa Lucken-Ardjomande, Sébastien Herzig, Robert Schwarzenbacher, Dietmar J Manstein, Ella Bossy-Wetzel, Gorka Basañez, Paolo Meda,[...]. Cell 2010
Sylvie Montessuit, Syam Prakash Somasekharan, Oihana Terrones, Safa Lucken-Ardjomande, Sébastien Herzig, Robert Schwarzenbacher, Dietmar J Manstein, Ella Bossy-Wetzel, Gorka Basañez, Paolo Meda,[...]. Cell 2010
7
Disruption of fusion results in mitochondrial heterogeneity and dysfunction.
Hsiuchen Chen, Anne Chomyn, David C Chan. J Biol Chem 2005
Hsiuchen Chen, Anne Chomyn, David C Chan. J Biol Chem 2005
7
Acute inhibition of excessive mitochondrial fission after myocardial infarction prevents long-term cardiac dysfunction.
Marie-Hélène Disatnik, Julio C B Ferreira, Juliane Cruz Campos, Kátia Sampaio Gomes, Paulo M M Dourado, Xin Qi, Daria Mochly-Rosen. J Am Heart Assoc 2013
Marie-Hélène Disatnik, Julio C B Ferreira, Juliane Cruz Campos, Kátia Sampaio Gomes, Paulo M M Dourado, Xin Qi, Daria Mochly-Rosen. J Am Heart Assoc 2013
7
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.