A citation-based method for searching scientific literature

David J Steger, Martina I Lefterova, Lei Ying, Aaron J Stonestrom, Michael Schupp, David Zhuo, Adam L Vakoc, Ja-Eun Kim, Junjie Chen, Mitchell A Lazar, Gerd A Blobel, Christopher R Vakoc. Mol Cell Biol 2008
Times Cited: 310







List of co-cited articles
1199 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


The diverse functions of Dot1 and H3K79 methylation.
Anh Tram Nguyen, Yi Zhang. Genes Dev 2011
355
33

Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain.
Qin Feng, Hengbin Wang, Huck Hui Ng, Hediye Erdjument-Bromage, Paul Tempst, Kevin Struhl, Yi Zhang. Curr Biol 2002
550
32

MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.
Kathrin M Bernt, Nan Zhu, Amit U Sinha, Sridhar Vempati, Joerg Faber, Andrei V Krivtsov, Zhaohui Feng, Natalie Punt, Amanda Daigle, Lars Bullinger,[...]. Cancer Cell 2011
576
31

hDOT1L links histone methylation to leukemogenesis.
Yuki Okada, Qin Feng, Yihui Lin, Qi Jiang, Yaqiang Li, Vernon M Coffield, Lishan Su, Guoliang Xu, Yi Zhang. Cell 2005
571
30

Potent inhibition of DOT1L as treatment of MLL-fusion leukemia.
Scott R Daigle, Edward J Olhava, Carly A Therkelsen, Aravind Basavapathruni, Lei Jin, P Ann Boriack-Sjodin, Christina J Allain, Christine R Klaus, Alejandra Raimondi, Margaret Porter Scott,[...]. Blood 2013
443
26

Dot1p modulates silencing in yeast by methylation of the nucleosome core.
Fred van Leeuwen, Philip R Gafken, Daniel E Gottschling. Cell 2002
605
25

The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure.
Brendan Jones, Hui Su, Audesh Bhat, Hong Lei, Jeffrey Bajko, Sarah Hevi, Gretchen A Baltus, Shilpa Kadam, Huili Zhai, Reginald Valdez,[...]. PLoS Genet 2008
229
24

Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor.
Scott R Daigle, Edward J Olhava, Carly A Therkelsen, Christina R Majer, Christopher J Sneeringer, Jeffrey Song, L Danielle Johnston, Margaret Porter Scott, Jesse J Smith, Yonghong Xiao,[...]. Cancer Cell 2011
629
22

High-resolution profiling of histone methylations in the human genome.
Artem Barski, Suresh Cuddapah, Kairong Cui, Tae-Young Roh, Dustin E Schones, Zhibin Wang, Gang Wei, Iouri Chepelev, Keji Zhao. Cell 2007
19

Combinatorial patterns of histone acetylations and methylations in the human genome.
Zhibin Wang, Chongzhi Zang, Jeffrey A Rosenfeld, Dustin E Schones, Artem Barski, Suresh Cuddapah, Kairong Cui, Tae-Young Roh, Weiqun Peng, Michael Q Zhang,[...]. Nat Genet 2008
18

H3K79 methylation profiles define murine and human MLL-AF4 leukemias.
Andrei V Krivtsov, Zhaohui Feng, Madeleine E Lemieux, Joerg Faber, Sridhar Vempati, Amit U Sinha, Xiaobo Xia, Jonathan Jesneck, Adrian P Bracken, Lewis B Silverman,[...]. Cancer Cell 2008
385
18

DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.
Chun-Wei Chen, Richard P Koche, Amit U Sinha, Aniruddha J Deshpande, Nan Zhu, Rowena Eng, John G Doench, Haiming Xu, Scott H Chu, Jun Qi,[...]. Nat Med 2015
133
18


A role for the MLL fusion partner ENL in transcriptional elongation and chromatin modification.
Dorothee Mueller, Christian Bach, Deniz Zeisig, Maria-Paz Garcia-Cuellar, Sara Monroe, Arun Sreekumar, Rong Zhou, Alexey Nesvizhskii, Arul Chinnaiyan, Jay L Hess,[...]. Blood 2007
273
16

Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom).
Man Mohan, Hans-Martin Herz, Yoh-Hei Takahashi, Chengqi Lin, Ka Chun Lai, Ying Zhang, Michael P Washburn, Laurence Florens, Ali Shilatifard. Genes Dev 2010
201
15

The emerging roles of DOT1L in leukemia and normal development.
C M McLean, I D Karemaker, F van Leeuwen. Leukemia 2014
76
19

The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia.
Eytan M Stein, Guillermo Garcia-Manero, David A Rizzieri, Raoul Tibes, Jesus G Berdeja, Michael R Savona, Mojca Jongen-Lavrenic, Jessica K Altman, Blythe Thomson, Stephen J Blakemore,[...]. Blood 2018
169
14



The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote.
Dirk Schübeler, David M MacAlpine, David Scalzo, Christiane Wirbelauer, Charles Kooperberg, Fred van Leeuwen, Daniel E Gottschling, Laura P O'Neill, Bryan M Turner, Jeffrey Delrow,[...]. Genes Dev 2004
592
13

Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation.
Robert K McGinty, Jaehoon Kim, Champak Chatterjee, Robert G Roeder, Tom W Muir. Nature 2008
346
13

Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association.
Huck Hui Ng, Qin Feng, Hengbin Wang, Hediye Erdjument-Bromage, Paul Tempst, Yi Zhang, Kevin Struhl. Genes Dev 2002
387
13

Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors.
Wenyu Yu, Emma J Chory, Amy K Wernimont, Wolfram Tempel, Alex Scopton, Alexander Federation, Jason J Marineau, Jun Qi, Dalia Barsyte-Lovejoy, Joanna Yi,[...]. Nat Commun 2012
181
13


MLL translocations, histone modifications and leukaemia stem-cell development.
Andrei V Krivtsov, Scott A Armstrong. Nat Rev Cancer 2007
775
12

Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.
Nicolas Lacoste, Rhea T Utley, Joanna M Hunter, Guy G Poirier, Jacques Côte. J Biol Chem 2002
216
12

Degree of recruitment of DOT1L to MLL-AF9 defines level of H3K79 Di- and tri-methylation on target genes and transformation potential.
Aravinda Kuntimaddi, Nicholas J Achille, Jeremy Thorpe, Alyson A Lokken, Ritambhara Singh, Charles S Hemenway, Mazhar Adli, Nancy J Zeleznik-Le, John H Bushweller. Cell Rep 2015
64
18

Chromatin-modifying enzymes as modulators of reprogramming.
Tamer T Onder, Nergis Kara, Anne Cherry, Amit U Sinha, Nan Zhu, Kathrin M Bernt, Patrick Cahan, B Ogan Marcarci, Juli Unternaehrer, Piyush B Gupta,[...]. Nature 2012
441
12

The upstreams and downstreams of H3K79 methylation by DOT1L.
Hanneke Vlaming, Fred van Leeuwen. Chromosoma 2016
42
26

DOT1L, the H3K79 methyltransferase, is required for MLL-AF9-mediated leukemogenesis.
Anh Tram Nguyen, Olena Taranova, Jin He, Yi Zhang. Blood 2011
174
11

The Polycomb complex PRC2 and its mark in life.
Raphaël Margueron, Danny Reinberg. Nature 2011
11

DOT1L and H3K79 Methylation in Transcription and Genomic Stability.
Katherine Wood, Michael Tellier, Shona Murphy. Biomolecules 2018
76
14

DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation.
Laura Godfrey, Nicholas T Crump, Ross Thorne, I-Jun Lau, Emmanouela Repapi, Dimitra Dimou, Alastair L Smith, Joe R Harman, Jelena M Telenius, A Marieke Oudelaar,[...]. Nat Commun 2019
38
28

AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes.
Aniruddha J Deshpande, Anagha Deshpande, Amit U Sinha, Liying Chen, Jenny Chang, Ali Cihan, Maurizio Fazio, Chun-Wei Chen, Nan Zhu, Richard Koche,[...]. Cancer Cell 2014
105
10

Nonprocessive methylation by Dot1 leads to functional redundancy of histone H3K79 methylation states.
Floor Frederiks, Manuel Tzouros, Gideon Oudgenoeg, Tibor van Welsem, Maarten Fornerod, Jeroen Krijgsveld, Fred van Leeuwen. Nat Struct Mol Biol 2008
114
10

Characterization of the grappa gene, the Drosophila histone H3 lysine 79 methyltransferase.
Gregory A Shanower, Martin Muller, Jason L Blanton, Viktor Honti, Henrik Gyurkovics, Paul Schedl. Genetics 2005
93
10

Interplay of chromatin modifiers on a short basic patch of histone H4 tail defines the boundary of telomeric heterochromatin.
Mohammed Altaf, Rhea T Utley, Nicolas Lacoste, Song Tan, Scott D Briggs, Jacques Côté. Mol Cell 2007
147
10

Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae.
M S Singer, A Kahana, A J Wolf, L L Meisinger, S E Peterson, C Goggin, M Mahowald, D E Gottschling. Genetics 1998
364
10

Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks.
Yentram Huyen, Omar Zgheib, Richard A Ditullio, Vassilis G Gorgoulis, Panayotis Zacharatos, Tom J Petty, Emily A Sheston, Hestia S Mellert, Elena S Stavridi, Thanos D Halazonetis. Nature 2004
652
10

AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia.
Chengqi Lin, Edwin R Smith, Hidehisa Takahashi, Ka Chun Lai, Skylar Martin-Brown, Laurence Florens, Michael P Washburn, Joan W Conaway, Ronald C Conaway, Ali Shilatifard. Mol Cell 2010
386
10

Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation.
Stephanie Y Jo, Eric M Granowicz, Ivan Maillard, Dafydd Thomas, Jay L Hess. Blood 2011
146
10

Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
Evan J Worden, Niklas A Hoffmann, Chad W Hicks, Cynthia Wolberger. Cell 2019
78
12

Structural Basis of Dot1L Stimulation by Histone H2B Lysine 120 Ubiquitination.
Marco Igor Valencia-Sánchez, Pablo De Ioannes, Miao Wang, Nikita Vasilyev, Ruoyu Chen, Evgeny Nudler, Jean-Paul Armache, Karim-Jean Armache. Mol Cell 2019
56
17

A bivalent chromatin structure marks key developmental genes in embryonic stem cells.
Bradley E Bernstein, Tarjei S Mikkelsen, Xiaohui Xie, Michael Kamal, Dana J Huebert, James Cuff, Ben Fry, Alex Meissner, Marius Wernig, Kathrin Plath,[...]. Cell 2006
9


Crystal structure of the nucleosome core particle at 2.8 A resolution.
K Luger, A W Mäder, R K Richmond, D F Sargent, T J Richmond. Nature 1997
9

Regulation of chromatin structure by site-specific histone H3 methyltransferases.
S Rea, F Eisenhaber, D O'Carroll, B D Strahl, Z W Sun, M Schmid, S Opravil, K Mechtler, C P Ponting, C D Allis,[...]. Nature 2000
9

Early mammalian erythropoiesis requires the Dot1L methyltransferase.
Yi Feng, Yanping Yang, Manoela M Ortega, Jessica N Copeland, Mingcai Zhang, Jennifer B Jacob, Timothy A Fields, Jay L Vivian, Patrick E Fields. Blood 2010
80
11

Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo.
Dmitry Borkin, Shihan He, Hongzhi Miao, Katarzyna Kempinska, Jonathan Pollock, Jennifer Chase, Trupta Purohit, Bhavna Malik, Ting Zhao, Jingya Wang,[...]. Cancer Cell 2015
194
9

Misguided transcriptional elongation causes mixed lineage leukemia.
Dorothee Mueller, María-Paz García-Cuéllar, Christian Bach, Sebastian Buhl, Emanuel Maethner, Robert K Slany. PLoS Biol 2009
145
9


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.