A citation-based method for searching scientific literature

Xiaofeng Zheng, Sarah Linke, José M Dias, Xiaowei Zheng, Katarina Gradin, Tristan P Wallis, Brett R Hamilton, Maria Gustafsson, Jorge L Ruas, Sarah Wilkins, Rebecca L Bilton, Kerstin Brismar, Murray L Whitelaw, Teresa Pereira, Jeffrey J Gorman, Johan Ericson, Daniel J Peet, Urban Lendahl, Lorenz Poellinger. Proc Natl Acad Sci U S A 2008
Times Cited: 192







List of co-cited articles
1271 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Hypoxia requires notch signaling to maintain the undifferentiated cell state.
Maria V Gustafsson, Xiaowei Zheng, Teresa Pereira, Katarina Gradin, Shaobo Jin, Johan Lundkvist, Jorge L Ruas, Lorenz Poellinger, Urban Lendahl, Maria Bondesson. Dev Cell 2005
830
49


FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor.
David Lando, Daniel J Peet, Jeffrey J Gorman, Dean A Whelan, Murray L Whitelaw, Richard K Bruick. Genes Dev 2002
26

Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor.
Mathew L Coleman, Michael A McDonough, Kirsty S Hewitson, Charlotte Coles, Jasmin Mecinovic, Mariola Edelmann, Kristina M Cook, Matthew E Cockman, David E Lancaster, Benedikt M Kessler,[...]. J Biol Chem 2007
167
25

Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH).
Matthew E Cockman, David E Lancaster, Ineke P Stolze, Kirsty S Hewitson, Michael A McDonough, Mathew L Coleman, Charlotte H Coles, Xiaohong Yu, Ronald T Hay, Steven C Ley,[...]. Proc Natl Acad Sci U S A 2006
220
21

The asparaginyl hydroxylase factor inhibiting HIF-1alpha is an essential regulator of metabolism.
Na Zhang, Zhenxing Fu, Sarah Linke, Johana Chicher, Jeffrey J Gorman, DeeAnn Visk, Gabriel G Haddad, Lorenz Poellinger, Daniel J Peet, Frank Powell,[...]. Cell Metab 2010
173
21

Notch signaling mediates hypoxia-induced tumor cell migration and invasion.
Cecilia Sahlgren, Maria V Gustafsson, Shaobo Jin, Lorenz Poellinger, Urban Lendahl. Proc Natl Acad Sci U S A 2008
588
20


Differences in hydroxylation and binding of Notch and HIF-1alpha demonstrate substrate selectivity for factor inhibiting HIF-1 (FIH-1).
Sarah E Wilkins, Jaana Hyvärinen, Johana Chicher, Jeffrey J Gorman, Daniel J Peet, Rebecca L Bilton, Peppi Koivunen. Int J Biochem Cell Biol 2009
45
40

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation.
A C Epstein, J M Gleadle, L A McNeill, K S Hewitson, J O'Rourke, D R Mole, M Mukherji, E Metzen, M I Wilson, A Dhanda,[...]. Cell 2001
17


Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation.
P Jaakkola, D R Mole, Y M Tian, M I Wilson, J Gielbert, S J Gaskell, A von Kriegsheim, H F Hebestreit, M Mukherji, C J Schofield,[...]. Science 2001
16

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch.
David Lando, Daniel J Peet, Dean A Whelan, Jeffrey J Gorman, Murray L Whitelaw. Science 2002
16

Hypoxia-mediated activation of Dll4-Notch-Hey2 signaling in endothelial progenitor cells and adoption of arterial cell fate.
Holger Diez, Andreas Fischer, Anja Winkler, Cheng-Jun Hu, Antonis K Hatzopoulos, Georg Breier, Manfred Gessler. Exp Cell Res 2007
164
16

Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family.
Kirsty S Hewitson, Luke A McNeill, Madeline V Riordan, Ya-Min Tian, Alex N Bullock, Richard W Welford, Jonathan M Elkins, Neil J Oldham, Shoumo Bhattacharya, Jonathan M Gleadle,[...]. J Biol Chem 2002
551
16


HIF-1α is critical for hypoxia-mediated maintenance of glioblastoma stem cells by activating Notch signaling pathway.
L Qiang, T Wu, H-W Zhang, N Lu, R Hu, Y-J Wang, L Zhao, F-H Chen, X-T Wang, Q-D You,[...]. Cell Death Differ 2012
208
12

Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases.
Peppi Koivunen, Maija Hirsilä, Volkmar Günzler, Kari I Kivirikko, Johanna Myllyharju. J Biol Chem 2004
316
11

Factor inhibiting HIF-1 (FIH-1) modulates protein interactions of apoptosis-stimulating p53 binding protein 2 (ASPP2).
Kirsten Janke, Ulf Brockmeier, Katja Kuhlmann, Martin Eisenacher, Jan Nolde, Helmut E Meyer, Heimo Mairbäurl, Eric Metzen. J Cell Sci 2013
35
31

Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors.
Ya-Min Tian, Kar Kheng Yeoh, Myung Kyu Lee, Tuula Eriksson, Benedikt M Kessler, Holger B Kramer, Mariola J Edelmann, Carsten Willam, Christopher W Pugh, Christopher J Schofield,[...]. J Biol Chem 2011
130
11

Factor inhibiting HIF (FIH) recognizes distinct molecular features within hypoxia-inducible factor-α (HIF-α) versus ankyrin repeat substrates.
Sarah E Wilkins, Sarah Karttunen, Rachel J Hampton-Smith, Iain Murchland, Anne Chapman-Smith, Daniel J Peet. J Biol Chem 2012
24
45

FIH-dependent asparaginyl hydroxylation of ankyrin repeat domain-containing proteins.
Matthew E Cockman, James D Webb, Peter J Ratcliffe. Ann N Y Acad Sci 2009
63
17

Interaction between Notch and Hif-alpha in development and survival of Drosophila blood cells.
Tina Mukherjee, William Sang Kim, Lolitika Mandal, Utpal Banerjee. Science 2011
126
10

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis.
P H Maxwell, M S Wiesener, G W Chang, S C Clifford, E C Vaux, M E Cockman, C C Wykoff, C W Pugh, E R Maher, P J Ratcliffe. Nature 1999
10

Notch signaling: simplicity in design, versatility in function.
Emma R Andersson, Rickard Sandberg, Urban Lendahl. Development 2011
657
10

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Andrew P Weng, Adolfo A Ferrando, Woojoong Lee, John P Morris, Lewis B Silverman, Cheryll Sanchez-Irizarry, Stephen C Blacklow, A Thomas Look, Jon C Aster. Science 2004
10

Targeting HIF-1 for cancer therapy.
Gregg L Semenza. Nat Rev Cancer 2003
10

Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response.
Kerstin Hein, Gerhard Mittler, Wiebke Cizelsky, Michael Kühl, Francesca Ferrante, Robert Liefke, Ina M Berger, Steffen Just, J Eric Sträng, Hans A Kestler,[...]. Sci Signal 2015
47
21

FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1.
Carsten C Scholz, Javier Rodriguez, Christina Pickel, Stephen Burr, Jacqueline-Alba Fabrizio, Karen A Nolan, Patrick Spielmann, Miguel A S Cavadas, Bianca Crifo, Doug N Halligan,[...]. PLoS Biol 2016
58
17


Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
G L Wang, B H Jiang, E A Rue, G L Semenza. Proc Natl Acad Sci U S A 1995
9

Notch-1 mediates hypoxia-induced angiogenesis in rheumatoid arthritis.
Wei Gao, Catherine Sweeney, Mary Connolly, Aisling Kennedy, Chin Teck Ng, Jennifer McCormick, Douglas J Veale, Ursula Fearon. Arthritis Rheum 2012
59
15

Oxygen sensing by HIF hydroxylases.
Christopher J Schofield, Peter J Ratcliffe. Nat Rev Mol Cell Biol 2004
9


Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase.
Virginia Guarani, Gianluca Deflorian, Claudio A Franco, Marcus Krüger, Li-Kun Phng, Katie Bentley, Louise Toussaint, Franck Dequiedt, Raul Mostoslavsky, Mirko H H Schmidt,[...]. Nature 2011
264
9

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
Jennifer O'Neil, Jonathan Grim, Peter Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James Hardwick, Markus Welcker, Jules P Meijerink, Rob Pieters,[...]. J Exp Med 2007
511
9

Notch signaling: cell fate control and signal integration in development.
S Artavanis-Tsakonas, M D Rand, R J Lake. Science 1999
9

Asparagine beta-hydroxylation stabilizes the ankyrin repeat domain fold.
Leanne Kelly, Michael A McDonough, Mathew L Coleman, Peter J Ratcliffe, Christopher J Schofield. Mol Biosyst 2009
44
20




Hypoxia-inducible factors and the response to hypoxic stress.
Amar J Majmundar, Waihay J Wong, M Celeste Simon. Mol Cell 2010
8

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing.
M Ivan, K Kondo, H Yang, W Kim, J Valiando, M Ohh, A Salic, J M Asara, W S Lane, W G Kaelin. Science 2001
8


Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis.
Irene Noguera-Troise, Christopher Daly, Nicholas J Papadopoulos, Sandra Coetzee, Pat Boland, Nicholas W Gale, Hsin Chieh Lin, George D Yancopoulos, Gavin Thurston. Nature 2006
789
8

Hypo- and hyperactivated Notch signaling induce a glycolytic switch through distinct mechanisms.
Sebastian K-J Landor, Anders P Mutvei, Veronika Mamaeva, Shaobo Jin, Morten Busk, Ronald Borra, Tove J Grönroos, Pauliina Kronqvist, Urban Lendahl, Cecilia Maria Sahlgren. Proc Natl Acad Sci U S A 2011
82
9

Asparagine and aspartate hydroxylation of the cytoskeletal ankyrin family is catalyzed by factor-inhibiting hypoxia-inducible factor.
Ming Yang, Wei Ge, Rasheduzzaman Chowdhury, Timothy D W Claridge, Holger B Kramer, Bernhard Schmierer, Michael A McDonough, Lingzhi Gong, Benedikt M Kessler, Peter J Ratcliffe,[...]. J Biol Chem 2011
47
17

Nontranscriptional role of Hif-1α in activation of γ-secretase and notch signaling in breast cancer.
Jennifer C Villa, Danica Chiu, Alissa H Brandes, Freddy E Escorcia, Carlos H Villa, William F Maguire, Cheng-Jun Hu, Elisa de Stanchina, M Celeste Simon, Sangram S Sisodia,[...]. Cell Rep 2014
87
9

Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel.
Sarah Karttunen, Michael Duffield, Nathan R Scrimgeour, Lauren Squires, Wai Li Lim, Mark L Dallas, Jason L Scragg, Johana Chicher, Keyur A Dave, Murray L Whitelaw,[...]. J Cell Sci 2015
30
26

The Notch signalling system: recent insights into the complexity of a conserved pathway.
K G Guruharsha, Mark W Kankel, Spyros Artavanis-Tsakonas. Nat Rev Genet 2012
483
7


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.