A citation-based method for searching scientific literature

L W Ellisen, J Bird, D C West, A L Soreng, T C Reynolds, S D Smith, J Sklar. Cell 1991
Times Cited: 1415







List of co-cited articles
1807 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Andrew P Weng, Adolfo A Ferrando, Woojoong Lee, John P Morris, Lewis B Silverman, Cheryll Sanchez-Irizarry, Stephen C Blacklow, A Thomas Look, Jon C Aster. Science 2004
59


FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
Jennifer O'Neil, Jonathan Grim, Peter Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James Hardwick, Markus Welcker, Jules P Meijerink, Rob Pieters,[...]. J Exp Med 2007
497
22

Notch1 functions as a tumor suppressor in mouse skin.
Michael Nicolas, Anita Wolfer, Kenneth Raj, J Alain Kummer, Pleasantine Mill, Mascha van Noort, Chi-chung Hui, Hans Clevers, G Paolo Dotto, Freddy Radtke. Nat Genet 2003
760
22

Notch signaling: cell fate control and signal integration in development.
S Artavanis-Tsakonas, M D Rand, R J Lake. Science 1999
21

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia.
Xose S Puente, Magda Pinyol, Víctor Quesada, Laura Conde, Gonzalo R Ordóñez, Neus Villamor, Georgia Escaramis, Pedro Jares, Sílvia Beà, Marcos González-Díaz,[...]. Nature 2011
20

Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1.
Nishant Agrawal, Mitchell J Frederick, Curtis R Pickering, Chetan Bettegowda, Kyle Chang, Ryan J Li, Carole Fakhry, Tong-Xin Xie, Jiexin Zhang, Jing Wang,[...]. Science 2011
20

Notch signalling in context.
Sarah J Bray. Nat Rev Mol Cell Biol 2016
489
20

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles.
W S Pear, J C Aster, M L Scott, R P Hasserjian, B Soffer, J Sklar, D Baltimore. J Exp Med 1996
564
19

The Varied Roles of Notch in Cancer.
Jon C Aster, Warren S Pear, Stephen C Blacklow. Annu Rev Pathol 2017
287
19

Therapeutic antibody targeting of individual Notch receptors.
Yan Wu, Carol Cain-Hom, Lisa Choy, Thijs J Hagenbeek, Gladys P de Leon, Yongmei Chen, David Finkle, Rayna Venook, Xiumin Wu, John Ridgway,[...]. Nature 2010
518
18

Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma.
Nicholas J Wang, Zachary Sanborn, Kelly L Arnett, Laura J Bayston, Wilson Liao, Charlotte M Proby, Irene M Leigh, Eric A Collisson, Patricia B Gordon, Lakshmi Jakkula,[...]. Proc Natl Acad Sci U S A 2011
312
18

Deficient T cell fate specification in mice with an induced inactivation of Notch1.
F Radtke, A Wilson, G Stark, M Bauer, J van Meerwijk, H R MacDonald, M Aguet. Immunity 1999
17

The mutational landscape of head and neck squamous cell carcinoma.
Nicolas Stransky, Ann Marie Egloff, Aaron D Tward, Aleksandar D Kostic, Kristian Cibulskis, Andrey Sivachenko, Gregory V Kryukov, Michael S Lawrence, Carrie Sougnez, Aaron McKenna,[...]. Science 2011
17

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia.
Teresa Palomero, Maria Luisa Sulis, Maria Cortina, Pedro J Real, Kelly Barnes, Maria Ciofani, Esther Caparros, Jean Buteau, Kristy Brown, Sherrie L Perkins,[...]. Nat Med 2007
663
16

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells.
Johan H van Es, Marielle E van Gijn, Orbicia Riccio, Maaike van den Born, Marc Vooijs, Harry Begthel, Miranda Cozijnsen, Sylvie Robine, Doug J Winton, Freddy Radtke,[...]. Nature 2005
15

c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma.
Andrew P Weng, John M Millholland, Yumi Yashiro-Ohtani, Marie Laure Arcangeli, Arthur Lau, Carol Wai, Cristina Del Bianco, Carlos G Rodriguez, Hong Sai, John Tobias,[...]. Genes Dev 2006
628
15

Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation.
A Rangarajan, C Talora, R Okuyama, M Nicolas, C Mammucari, H Oh, J C Aster, S Krishna, D Metzger, P Chambon,[...]. EMBO J 2001
670
15

A new tumor suppressor role for the Notch pathway in bladder cancer.
Theodoros Rampias, Paraskevi Vgenopoulou, Margaritis Avgeris, Alexander Polyzos, Konstantinos Stravodimos, Christos Valavanis, Andreas Scorilas, Apostolos Klinakis. Nat Med 2014
122
14

A Phase 1 study of the novel gamma-secretase inhibitor PF-03084014 in patients with T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma.
C Papayannidis, D J DeAngelo, W Stock, B Huang, M N Shaik, R Cesari, X Zheng, J M Reynolds, P A English, M Ozeck,[...]. Blood Cancer J 2015
71
19

Alterations of the Notch pathway in lung cancer.
Britta Westhoff, Ivan N Colaluca, Giovanni D'Ario, Maddalena Donzelli, Daniela Tosoni, Sara Volorio, Giuseppe Pelosi, Lorenzo Spaggiari, Giovanni Mazzarol, Giuseppe Viale,[...]. Proc Natl Acad Sci U S A 2009
297
13

Notch1 expression in early lymphopoiesis influences B versus T lineage determination.
J C Pui, D Allman, L Xu, S DeRocco, F G Karnell, S Bakkour, J Y Lee, T Kadesch, R R Hardy, J C Aster,[...]. Immunity 1999
743
13


Direct inhibition of the NOTCH transcription factor complex.
Raymond E Moellering, Melanie Cornejo, Tina N Davis, Cristina Del Bianco, Jon C Aster, Stephen C Blacklow, Andrew L Kung, D Gary Gilliland, Gregory L Verdine, James E Bradner. Nature 2009
562
13

Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation.
Giulia Fabbri, Silvia Rasi, Davide Rossi, Vladimir Trifonov, Hossein Khiabanian, Jing Ma, Adina Grunn, Marco Fangazio, Daniela Capello, Sara Monti,[...]. J Exp Med 2011
442
13

A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia.
Apostolos Klinakis, Camille Lobry, Omar Abdel-Wahab, Philmo Oh, Hiroshi Haeno, Silvia Buonamici, Inge van De Walle, Severine Cathelin, Thomas Trimarchi, Elisa Araldi,[...]. Nature 2011
279
13

Whole-genome sequencing identifies recurrent somatic NOTCH2 mutations in splenic marginal zone lymphoma.
Mark J Kiel, Thirunavukkarasu Velusamy, Bryan L Betz, Lili Zhao, Helmut G Weigelin, Mark Y Chiang, David R Huebner-Chan, Nathanael G Bailey, David T Yang, Govind Bhagat,[...]. J Exp Med 2012
200
13

Notch Signaling in Development, Tissue Homeostasis, and Disease.
Chris Siebel, Urban Lendahl. Physiol Rev 2017
364
13

Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma.
Robert Kridel, Barbara Meissner, Sanja Rogic, Merrill Boyle, Adele Telenius, Bruce Woolcock, Jay Gunawardana, Christopher Jenkins, Chris Cochrane, Susana Ben-Neriah,[...]. Blood 2012
233
12

Notch signalling in solid tumours: a little bit of everything but not all the time.
Prathibha Ranganathan, Kelly L Weaver, Anthony J Capobianco. Nat Rev Cancer 2011
566
12


Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor.
Hannah Harrison, Gillian Farnie, Sacha J Howell, Rebecca E Rock, Spyros Stylianou, Keith R Brennan, Nigel J Bundred, Robert B Clarke. Cancer Res 2010
369
12

High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival.
Michael Reedijk, Silvia Odorcic, Lynn Chang, Hui Zhang, Naomi Miller, David R McCready, Gina Lockwood, Sean E Egan. Cancer Res 2005
565
12

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE.
C Brou, F Logeat, N Gupta, C Bessia, O LeBail, J R Doedens, A Cumano, P Roux, R A Black, A Israël. Mol Cell 2000
842
12

Therapeutic modulation of Notch signalling--are we there yet?
Emma R Andersson, Urban Lendahl. Nat Rev Drug Discov 2014
316
12

Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia.
Pedro J Real, Valeria Tosello, Teresa Palomero, Mireia Castillo, Eva Hernando, Elisa de Stanchina, Maria Luisa Sulis, Kelly Barnes, Catherine Sawai, Irene Homminga,[...]. Nat Med 2009
325
12

The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development.
Davide Rossi, Vladimir Trifonov, Marco Fangazio, Alessio Bruscaggin, Silvia Rasi, Valeria Spina, Sara Monti, Tiziana Vaisitti, Francesca Arruga, Rosella Famà,[...]. J Exp Med 2012
258
12

Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer.
Giovanni Roti, Anne Carlton, Kenneth N Ross, Michele Markstein, Kostandin Pajcini, Angela H Su, Norbert Perrimon, Warren S Pear, Andrew L Kung, Stephen C Blacklow,[...]. Cancer Cell 2013
96
11

Targeting Notch signaling with a Notch2/Notch3 antagonist (tarextumab) inhibits tumor growth and decreases tumor-initiating cell frequency.
Wan-Ching Yen, Marcus M Fischer, Fumiko Axelrod, Christopher Bond, Jennifer Cain, Belinda Cancilla, William R Henner, Rene Meisner, Aaron Sato, Jalpa Shah,[...]. Clin Cancer Res 2015
163
11

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth.
Teresa Palomero, Wei Keat Lim, Duncan T Odom, Maria Luisa Sulis, Pedro J Real, Adam Margolin, Kelly C Barnes, Jennifer O'Neil, Donna Neuberg, Andrew P Weng,[...]. Proc Natl Acad Sci U S A 2006
595
11

Notch signalling: a simple pathway becomes complex.
Sarah J Bray. Nat Rev Mol Cell Biol 2006
11

Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2.
Orbicia Riccio, Marielle E van Gijn, April C Bezdek, Luca Pellegrinet, Johan H van Es, Ursula Zimber-Strobl, Lothar J Strobl, Tasuku Honjo, Hans Clevers, Freddy Radtke. EMBO Rep 2008
290
11

Structural basis for autoinhibition of Notch.
Wendy R Gordon, Didem Vardar-Ulu, Gavin Histen, Cheryll Sanchez-Irizarry, Jon C Aster, Stephen C Blacklow. Nat Struct Mol Biol 2007
236
11

Notch as a tumour suppressor.
Craig S Nowell, Freddy Radtke. Nat Rev Cancer 2017
192
11

Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation.
Joseph Milano, Jenny McKay, Claude Dagenais, Linda Foster-Brown, Francois Pognan, Reto Gadient, Robert T Jacobs, Anna Zacco, Barry Greenberg, Paul J Ciaccio. Toxicol Sci 2004
413
11

NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers.
Hongfang Wang, Chongzhi Zang, Len Taing, Kelly L Arnett, Yinling Joey Wong, Warren S Pear, Stephen C Blacklow, X Shirley Liu, Jon C Aster. Proc Natl Acad Sci U S A 2014
153
11

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.
L Wu, J C Aster, S C Blacklow, R Lake, S Artavanis-Tsakonas, J D Griffin. Nat Genet 2000
441
11

A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia.
Daniel Herranz, Alberto Ambesi-Impiombato, Teresa Palomero, Stephanie A Schnell, Laura Belver, Agnieszka A Wendorff, Luyao Xu, Mireia Castillo-Martin, David Llobet-Navás, Carlos Cordon-Cardo,[...]. Nat Med 2014
255
11

A Phase I First-in-Human Study of Enoticumab (REGN421), a Fully Human Delta-like Ligand 4 (Dll4) Monoclonal Antibody in Patients with Advanced Solid Tumors.
Elena Gabriela Chiorean, Patricia LoRusso, Robert Matthew Strother, Jennifer R Diamond, Anne Younger, Wells A Messersmith, Lieve Adriaens, Liming Liu, Richard J Kao, Albert Thomas DiCioccio,[...]. Clin Cancer Res 2015
81
13

Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition.
Roger A Habets, Charles E de Bock, Lutgarde Serneels, Inge Lodewijckx, Delphine Verbeke, David Nittner, Rajeshwar Narlawar, Sofie Demeyer, James Dooley, Adrian Liston,[...]. Sci Transl Med 2019
48
22


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.