Christopher A Jones, Nyall R London, Haoyu Chen, Kye Won Park, Dominique Sauvaget, Rebecca A Stockton, Joshua D Wythe, Wonhee Suh, Frederic Larrieu-Lahargue, Yoh-Suke Mukouyama, Per Lindblom, Pankaj Seth, Antonio Frias, Naoyuki Nishiya, Mark H Ginsberg, Holger Gerhardt, Kang Zhang, Dean Y Li. Nat Med 2008
Times Cited: 282
Times Cited: 282
Times Cited
Times Co-cited
Similarity
Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity.
Christopher A Jones, Naoyuki Nishiya, Nyall R London, Weiquan Zhu, Lise K Sorensen, Aubrey C Chan, Chinten J Lim, Haoyu Chen, Qisheng Zhang, Peter G Schultz,[...]. Nat Cell Biol 2009
Christopher A Jones, Naoyuki Nishiya, Nyall R London, Weiquan Zhu, Lise K Sorensen, Aubrey C Chan, Chinten J Lim, Haoyu Chen, Qisheng Zhang, Peter G Schultz,[...]. Nat Cell Biol 2009
34
Magic roundabout is a new member of the roundabout receptor family that is endothelial specific and expressed at sites of active angiogenesis.
Lukasz Huminiecki, Michael Gorn, Steven Suchting, Richard Poulsom, Roy Bicknell. Genomics 2002
Lukasz Huminiecki, Michael Gorn, Steven Suchting, Richard Poulsom, Roy Bicknell. Genomics 2002
32
Robo4 is a vascular-specific receptor that inhibits endothelial migration.
Kye Won Park, Clayton M Morrison, Lise K Sorensen, Christopher A Jones, Yi Rao, Chi-Bin Chien, Jane Y Wu, Lisa D Urness, Dean Y Li. Dev Biol 2003
Kye Won Park, Clayton M Morrison, Lise K Sorensen, Christopher A Jones, Yi Rao, Chi-Bin Chien, Jane Y Wu, Lisa D Urness, Dean Y Li. Dev Biol 2003
32
Robo4 maintains vessel integrity and inhibits angiogenesis by interacting with UNC5B.
Alexander W Koch, Thomas Mathivet, Bruno Larrivée, Raymond K Tong, Joe Kowalski, Laurence Pibouin-Fragner, Karine Bouvrée, Scott Stawicki, Katrina Nicholes, Nisha Rathore,[...]. Dev Cell 2011
Alexander W Koch, Thomas Mathivet, Bruno Larrivée, Raymond K Tong, Joe Kowalski, Laurence Pibouin-Fragner, Karine Bouvrée, Scott Stawicki, Katrina Nicholes, Nisha Rathore,[...]. Dev Cell 2011
30
Targeting Robo4-dependent Slit signaling to survive the cytokine storm in sepsis and influenza.
Nyall R London, Weiquan Zhu, Fernando A Bozza, Matthew C P Smith, Daniel M Greif, Lise K Sorensen, Luming Chen, Yuuki Kaminoh, Aubrey C Chan, Samuel F Passi,[...]. Sci Transl Med 2010
Nyall R London, Weiquan Zhu, Fernando A Bozza, Matthew C P Smith, Daniel M Greif, Lise K Sorensen, Luming Chen, Yuuki Kaminoh, Aubrey C Chan, Samuel F Passi,[...]. Sci Transl Med 2010
25
Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization.
Nicolas Rama, Alexandre Dubrac, Thomas Mathivet, Róisín-Ana Ní Chárthaigh, Gael Genet, Brunella Cristofaro, Laurence Pibouin-Fragner, Le Ma, Anne Eichmann, Alain Chédotal. Nat Med 2015
Nicolas Rama, Alexandre Dubrac, Thomas Mathivet, Róisín-Ana Ní Chárthaigh, Gael Genet, Brunella Cristofaro, Laurence Pibouin-Fragner, Le Ma, Anne Eichmann, Alain Chédotal. Nat Med 2015
21
Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity.
Biao Wang, Yang Xiao, Bei Bei Ding, Na Zhang, Xiao bin Yuan, Lü Gui, Kai Xian Qian, Shumin Duan, Zhengjun Chen, Yi Rao,[...]. Cancer Cell 2003
Biao Wang, Yang Xiao, Bei Bei Ding, Na Zhang, Xiao bin Yuan, Lü Gui, Kai Xian Qian, Shumin Duan, Zhengjun Chen, Yi Rao,[...]. Cancer Cell 2003
19
The Robo4 cytoplasmic domain is dispensable for vascular permeability and neovascularization.
Feng Zhang, Claudia Prahst, Thomas Mathivet, Laurence Pibouin-Fragner, Jiasheng Zhang, Gael Genet, Raymond Tong, Alexandre Dubrac, Anne Eichmann. Nat Commun 2016
Feng Zhang, Claudia Prahst, Thomas Mathivet, Laurence Pibouin-Fragner, Jiasheng Zhang, Gael Genet, Raymond Tong, Alexandre Dubrac, Anne Eichmann. Nat Commun 2016
59
Active involvement of Robo1 and Robo4 in filopodia formation and endothelial cell motility mediated via WASP and other actin nucleation-promoting factors.
Helen Sheldon, Maud Andre, John A Legg, Paul Heal, John M Herbert, Richard Sainson, Anshula S Sharma, Jan K Kitajewski, Victoria L Heath, Roy Bicknell. FASEB J 2009
Helen Sheldon, Maud Andre, John A Legg, Paul Heal, John M Herbert, Richard Sainson, Anshula S Sharma, Jan K Kitajewski, Victoria L Heath, Roy Bicknell. FASEB J 2009
19
Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance.
K Brose, K S Bland, K H Wang, D Arnott, W Henzel, C S Goodman, M Tessier-Lavigne, T Kidd. Cell 1999
K Brose, K S Bland, K H Wang, D Arnott, W Henzel, C S Goodman, M Tessier-Lavigne, T Kidd. Cell 1999
17
Slit2-Robo4 pathway modulates lipopolysaccharide-induced endothelial inflammation and its expression is dysregulated during endotoxemia.
Helong Zhao, Appakkudal R Anand, Ramesh K Ganju. J Immunol 2014
Helong Zhao, Appakkudal R Anand, Ramesh K Ganju. J Immunol 2014
25
Vascular Robo4 restricts proangiogenic VEGF signaling in breast.
Rebecca Marlow, Mikhail Binnewies, Lise K Sorensen, Stefanie D Monica, Phyllis Strickland, E Camilla Forsberg, Dean Y Li, Lindsay Hinck. Proc Natl Acad Sci U S A 2010
Rebecca Marlow, Mikhail Binnewies, Lise K Sorensen, Stefanie D Monica, Phyllis Strickland, E Camilla Forsberg, Dean Y Li, Lindsay Hinck. Proc Natl Acad Sci U S A 2010
23
roundabout4 is essential for angiogenesis in vivo.
Victoria M Bedell, Sang-Yeob Yeo, Kye Won Park, Jeffrey Chung, Pankaj Seth, Venkatesha Shivalingappa, Jinhua Zhao, Tomoko Obara, Vikas P Sukhatme, Iain A Drummond,[...]. Proc Natl Acad Sci U S A 2005
Victoria M Bedell, Sang-Yeob Yeo, Kye Won Park, Jeffrey Chung, Pankaj Seth, Venkatesha Shivalingappa, Jinhua Zhao, Tomoko Obara, Vikas P Sukhatme, Iain A Drummond,[...]. Proc Natl Acad Sci U S A 2005
15
Soluble Robo4 receptor inhibits in vivo angiogenesis and endothelial cell migration.
Steven Suchting, Paul Heal, Kiki Tahtis, Lorna M Stewart, Roy Bicknell. FASEB J 2005
Steven Suchting, Paul Heal, Kiki Tahtis, Lorna M Stewart, Roy Bicknell. FASEB J 2005
15
The neuronal repellent Slit inhibits leukocyte chemotaxis induced by chemotactic factors.
J Y Wu, L Feng, H T Park, N Havlioglu, L Wen, H Tang, K B Bacon, Jiang Zh, Zhang Xc, Y Rao. Nature 2001
J Y Wu, L Feng, H T Park, N Havlioglu, L Wen, H Tang, K B Bacon, Jiang Zh, Zhang Xc, Y Rao. Nature 2001
14
Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors.
T Kidd, K Brose, K J Mitchell, R D Fetter, M Tessier-Lavigne, C S Goodman, G Tear. Cell 1998
T Kidd, K Brose, K J Mitchell, R D Fetter, M Tessier-Lavigne, C S Goodman, G Tear. Cell 1998
14
Repulsive axon guidance molecule Slit3 is a novel angiogenic factor.
Bing Zhang, Ursula M Dietrich, Jian-Guo Geng, Roy Bicknell, Jeffrey D Esko, Lianchun Wang. Blood 2009
Bing Zhang, Ursula M Dietrich, Jian-Guo Geng, Roy Bicknell, Jeffrey D Esko, Lianchun Wang. Blood 2009
14
Structural insights into the Slit-Robo complex.
Cecile Morlot, Nicole M Thielens, Raimond B G Ravelli, Wieger Hemrika, Roland A Romijn, Piet Gros, Stephen Cusack, Andrew A McCarthy. Proc Natl Acad Sci U S A 2007
Cecile Morlot, Nicole M Thielens, Raimond B G Ravelli, Wieger Hemrika, Roland A Romijn, Piet Gros, Stephen Cusack, Andrew A McCarthy. Proc Natl Acad Sci U S A 2007
14
Magic roundabout, a tumor endothelial marker: expression and signaling.
Pankaj Seth, Yanfeng Lin, Jun-ichi Hanai, Venkatesha Shivalingappa, Mabel P Duyao, Vikas P Sukhatme. Biochem Biophys Res Commun 2005
Pankaj Seth, Yanfeng Lin, Jun-ichi Hanai, Venkatesha Shivalingappa, Mabel P Duyao, Vikas P Sukhatme. Biochem Biophys Res Commun 2005
13
A three-kilobase fragment of the human Robo4 promoter directs cell type-specific expression in endothelium.
Yoshiaki Okada, Kiichiro Yano, Enjing Jin, Nobuaki Funahashi, Mie Kitayama, Takefumi Doi, Katherine Spokes, David L Beeler, Shu-Ching Shih, Hitomi Okada,[...]. Circ Res 2007
Yoshiaki Okada, Kiichiro Yano, Enjing Jin, Nobuaki Funahashi, Mie Kitayama, Takefumi Doi, Katherine Spokes, David L Beeler, Shu-Ching Shih, Hitomi Okada,[...]. Circ Res 2007
20
Investigation of the Regulation of Roundabout4 by Hypoxia-Inducible Factor-1α in Microvascular Endothelial Cells.
Rui Tian, Zaoxia Liu, Hui Zhang, Xuexun Fang, Chenguang Wang, Shounan Qi, Yan Cheng, Guanfang Su. Invest Ophthalmol Vis Sci 2015
Rui Tian, Zaoxia Liu, Hui Zhang, Xuexun Fang, Chenguang Wang, Shounan Qi, Yan Cheng, Guanfang Su. Invest Ophthalmol Vis Sci 2015
66
Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.
K Wong, X R Ren, Y Z Huang, Y Xie, G Liu, H Saito, H Tang, L Wen, S M Brady-Kalnay, L Mei,[...]. Cell 2001
K Wong, X R Ren, Y Z Huang, Y Xie, G Liu, H Saito, H Tang, L Wen, S M Brady-Kalnay, L Mei,[...]. Cell 2001
10
SLIT2-mediated ROBO2 signaling restricts kidney induction to a single site.
Uta Grieshammer, Le Ma, Andrew S Plump, Fan Wang, Marc Tessier-Lavigne, Gail R Martin. Dev Cell 2004
Uta Grieshammer, Le Ma, Andrew S Plump, Fan Wang, Marc Tessier-Lavigne, Gail R Martin. Dev Cell 2004
10
Expression of Robo4 in the fibrovascular membranes from patients with proliferative diabetic retinopathy and its role in RF/6A and RPE cells.
Lvzhen Huang, Wenzhen Yu, Xiaoxin Li, Yongsheng Xu, Lanjun Niu, Xiangjun He, Jianqiang Dong, Zheng Yan. Mol Vis 2009
Lvzhen Huang, Wenzhen Yu, Xiaoxin Li, Yongsheng Xu, Lanjun Niu, Xiangjun He, Jianqiang Dong, Zheng Yan. Mol Vis 2009
33
Slit-2/Robo-1 modulates the CXCL12/CXCR4-induced chemotaxis of T cells.
Anil Prasad, Zahida Qamri, Jane Wu, Ramesh K Ganju. J Leukoc Biol 2007
Anil Prasad, Zahida Qamri, Jane Wu, Ramesh K Ganju. J Leukoc Biol 2007
11
Endothelial Robo4 suppresses breast cancer growth and metastasis through regulation of tumor angiogenesis.
Helong Zhao, Dinesh K Ahirwar, Steve Oghumu, Tasha Wilkie, Catherine A Powell, Mohd W Nasser, Abhay R Satoskar, Dean Y Li, Ramesh K Ganju. Mol Oncol 2016
Helong Zhao, Dinesh K Ahirwar, Steve Oghumu, Tasha Wilkie, Catherine A Powell, Mohd W Nasser, Abhay R Satoskar, Dean Y Li, Ramesh K Ganju. Mol Oncol 2016
36
Slit-2 induces a tumor-suppressive effect by regulating beta-catenin in breast cancer cells.
Anil Prasad, Vikram Paruchuri, Anju Preet, Farida Latif, Ramesh K Ganju. J Biol Chem 2008
Anil Prasad, Vikram Paruchuri, Anju Preet, Farida Latif, Ramesh K Ganju. J Biol Chem 2008
10
Robo4 signaling in endothelial cells implies attraction guidance mechanisms.
Sukhbir Kaur, Maria Domenica Castellone, Victoria M Bedell, Martha Konar, J Silvio Gutkind, Ramani Ramchandran. J Biol Chem 2006
Sukhbir Kaur, Maria Domenica Castellone, Victoria M Bedell, Martha Konar, J Silvio Gutkind, Ramani Ramchandran. J Biol Chem 2006
13
Endothelial cell-specific expression of roundabout 4 is regulated by differential DNA methylation of the proximal promoter.
Yoshiaki Okada, Nobuaki Funahashi, Toru Tanaka, Yuji Nishiyama, Lei Yuan, Keisuke Shirakura, Alexis S Turjman, Yoshihiro Kano, Hiroki Naruse, Ayano Suzuki,[...]. Arterioscler Thromb Vasc Biol 2014
Yoshiaki Okada, Nobuaki Funahashi, Toru Tanaka, Yuji Nishiyama, Lei Yuan, Keisuke Shirakura, Alexis S Turjman, Yoshihiro Kano, Hiroki Naruse, Ayano Suzuki,[...]. Arterioscler Thromb Vasc Biol 2014
56
Regulation of commissural axon pathfinding by slit and its Robo receptors.
Barry J Dickson, Giorgio F Gilestro. Annu Rev Cell Dev Biol 2006
Barry J Dickson, Giorgio F Gilestro. Annu Rev Cell Dev Biol 2006
8
Silencing of directional migration in roundabout4 knockdown endothelial cells.
Sukhbir Kaur, Ganesh V Samant, Kallal Pramanik, Philip W Loscombe, Michael L Pendrak, David D Roberts, Ramani Ramchandran. BMC Cell Biol 2008
Sukhbir Kaur, Ganesh V Samant, Kallal Pramanik, Philip W Loscombe, Michael L Pendrak, David D Roberts, Ramani Ramchandran. BMC Cell Biol 2008
23
Molecular mechanisms and clinical applications of angiogenesis.
Peter Carmeliet, Rakesh K Jain. Nature 2011
Peter Carmeliet, Rakesh K Jain. Nature 2011
8
The chemorepellent Slit3 promotes monocyte migration.
Sacha B Geutskens, Peter L Hordijk, Paula B van Hennik. J Immunol 2010
Sacha B Geutskens, Peter L Hordijk, Paula B van Hennik. J Immunol 2010
22
Slit is the midline repellent for the robo receptor in Drosophila.
T Kidd, K S Bland, C S Goodman. Cell 1999
T Kidd, K S Bland, C S Goodman. Cell 1999
8
Roundabout 4 regulates blood-tumor barrier permeability through the modulation of ZO-1, Occludin, and Claudin-5 expression.
Heng Cai, Wenjing Liu, Yixue Xue, Xiuli Shang, Jing Liu, Zhen Li, Ping Wang, Libo Liu, Yi Hu, Yunhui Liu. J Neuropathol Exp Neurol 2015
Heng Cai, Wenjing Liu, Yixue Xue, Xiuli Shang, Jing Liu, Zhen Li, Ping Wang, Libo Liu, Yi Hu, Yunhui Liu. J Neuropathol Exp Neurol 2015
25
Slit2 Promotes Angiogenic Activity Via the Robo1-VEGFR2-ERK1/2 Pathway in Both In Vivo and In Vitro Studies.
Shanshan Li, Lvzhen Huang, Yaoyao Sun, Yujing Bai, Fei Yang, Wenzhen Yu, Fangting Li, Qi Zhang, Bin Wang, Jian-Guo Geng,[...]. Invest Ophthalmol Vis Sci 2015
Shanshan Li, Lvzhen Huang, Yaoyao Sun, Yujing Bai, Fei Yang, Wenzhen Yu, Fangting Li, Qi Zhang, Bin Wang, Jian-Guo Geng,[...]. Invest Ophthalmol Vis Sci 2015
29
Axon guidance factor SLIT2 inhibits neural invasion and metastasis in pancreatic cancer.
Andreas Göhrig, Katharina M Detjen, Georg Hilfenhaus, Jan L Körner, Martina Welzel, Ruza Arsenic, Rosa Schmuck, Marcus Bahra, Jane Y Wu, Bertram Wiedenmann,[...]. Cancer Res 2014
Andreas Göhrig, Katharina M Detjen, Georg Hilfenhaus, Jan L Körner, Martina Welzel, Ruza Arsenic, Rosa Schmuck, Marcus Bahra, Jane Y Wu, Bertram Wiedenmann,[...]. Cancer Res 2014
12
Diversity and specificity of actions of Slit2 proteolytic fragments in axon guidance.
K T Nguyen Ba-Charvet, K Brose, L Ma, K H Wang, V Marillat, C Sotelo, M Tessier-Lavigne, A Chédotal. J Neurosci 2001
K T Nguyen Ba-Charvet, K Brose, L Ma, K H Wang, V Marillat, C Sotelo, M Tessier-Lavigne, A Chédotal. J Neurosci 2001
8
Robo1/Robo4: differential expression of angiogenic markers in colorectal cancer.
Jörn Gröne, Oliver Doebler, Christoph Loddenkemper, Birgit Hotz, Heinz-Johannes Buhr, Sarah Bhargava. Oncol Rep 2006
Jörn Gröne, Oliver Doebler, Christoph Loddenkemper, Birgit Hotz, Heinz-Johannes Buhr, Sarah Bhargava. Oncol Rep 2006
13
Suppression of Slit2/Robo1 mediated HUVEC migration by Robo4.
Satoshi Enomoto, Kenichi Mitsui, Takeshi Kawamura, Hiroko Iwanari, Kenji Daigo, Keiko Horiuchi, Takashi Minami, Tatsuhiko Kodama, Takao Hamakubo. Biochem Biophys Res Commun 2016
Satoshi Enomoto, Kenichi Mitsui, Takeshi Kawamura, Hiroko Iwanari, Kenji Daigo, Keiko Horiuchi, Takashi Minami, Tatsuhiko Kodama, Takao Hamakubo. Biochem Biophys Res Commun 2016
44
Role of ROBO4 signalling in developmental and pathological angiogenesis.
Suresh Singh Yadav, Gopeshwar Narayan. Biomed Res Int 2014
Suresh Singh Yadav, Gopeshwar Narayan. Biomed Res Int 2014
34
A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish.
Jason E Fish, Joshua D Wythe, Tong Xiao, Benoit G Bruneau, Didier Y R Stainier, Deepak Srivastava, Stephanie Woo. Development 2011
Jason E Fish, Joshua D Wythe, Tong Xiao, Benoit G Bruneau, Didier Y R Stainier, Deepak Srivastava, Stephanie Woo. Development 2011
7
Over-expression of Slit2 induces vessel formation and changes blood vessel permeability in mouse brain.
Hai-xiong Han, Jian-guo Geng. Acta Pharmacol Sin 2011
Hai-xiong Han, Jian-guo Geng. Acta Pharmacol Sin 2011
30
Robo4 cooperates with CXCR4 to specify hematopoietic stem cell localization to bone marrow niches.
Stephanie Smith-Berdan, Andrew Nguyen, Deena Hassanein, Matthew Zimmer, Fernando Ugarte, Jesús Ciriza, Dean Li, Marcos E García-Ojeda, Lindsay Hinck, E Camilla Forsberg. Cell Stem Cell 2011
Stephanie Smith-Berdan, Andrew Nguyen, Deena Hassanein, Matthew Zimmer, Fernando Ugarte, Jesús Ciriza, Dean Li, Marcos E García-Ojeda, Lindsay Hinck, E Camilla Forsberg. Cell Stem Cell 2011
7
Favorable prognosis of operable non-small cell lung cancer (NSCLC) patients harboring an increased expression of tumor endothelial markers (TEMs).
Andreas Pircher, Michael Fiegl, Gerold Untergasser, Isabel Heidegger, Michael Medinger, Johann Kern, Wolfgang Hilbe. Lung Cancer 2013
Andreas Pircher, Michael Fiegl, Gerold Untergasser, Isabel Heidegger, Michael Medinger, Johann Kern, Wolfgang Hilbe. Lung Cancer 2013
41
Moving away from the midline: new developments for Slit and Robo.
Athena R Ypsilanti, Yvrick Zagar, Alain Chédotal. Development 2010
Athena R Ypsilanti, Yvrick Zagar, Alain Chédotal. Development 2010
7
Mutations affecting growth cone guidance in Drosophila: genes necessary for guidance toward or away from the midline.
M Seeger, G Tear, D Ferres-Marco, C S Goodman. Neuron 1993
M Seeger, G Tear, D Ferres-Marco, C S Goodman. Neuron 1993
7
slit: an EGF-homologous locus of D. melanogaster involved in the development of the embryonic central nervous system.
J M Rothberg, D A Hartley, Z Walther, S Artavanis-Tsakonas. Cell 1988
J M Rothberg, D A Hartley, Z Walther, S Artavanis-Tsakonas. Cell 1988
7
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.