A citation-based method for searching scientific literature

Sahoko Matsuoka, Yuichi Oike, Ichiro Onoyama, Atsushi Iwama, Fumio Arai, Keiyo Takubo, Yoichi Mashimo, Hideyuki Oguro, Eriko Nitta, Keisuke Ito, Kana Miyamoto, Hiroki Yoshiwara, Kentaro Hosokawa, Yuka Nakamura, Yumiko Gomei, Hiroko Iwasaki, Yasuhide Hayashi, Yumi Matsuzaki, Keiko Nakayama, Yasuo Ikeda, Akira Hata, Shigeru Chiba, Keiichi I Nakayama, Toshio Suda. Genes Dev 2008
Times Cited: 145







List of co-cited articles
1406 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7.
Benjamin J Thompson, Vladimir Jankovic, Jie Gao, Silvia Buonamici, Alan Vest, Jennifer May Lee, Jiri Zavadil, Stephen D Nimer, Iannis Aifantis. J Exp Med 2008
128
48

Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis.
Ichiro Onoyama, Ryosuke Tsunematsu, Akinobu Matsumoto, Taichi Kimura, Ignacio Moreno de Alborán, Keiko Nakayama, Keiichi I Nakayama. J Exp Med 2007
151
46


FBXW7/hCDC4 is a general tumor suppressor in human cancer.
Shahab Akhoondi, Dahui Sun, Natalie von der Lehr, Sophia Apostolidou, Kathleen Klotz, Alena Maljukova, Diana Cepeda, Heidi Fiegl, Dimitra Dafou, Christian Marth,[...]. Cancer Res 2007
372
34

SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
Hiroyuki Inuzuka, Shavali Shaik, Ichiro Onoyama, Daming Gao, Alan Tseng, Richard S Maser, Bo Zhai, Lixin Wan, Alejandro Gutierrez, Alan W Lau,[...]. Nature 2011
477
33

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.
Masayoshi Yada, Shigetsugu Hatakeyama, Takumi Kamura, Masaaki Nishiyama, Ryosuke Tsunematsu, Hiroyuki Imaki, Noriko Ishida, Fumihiko Okumura, Keiko Nakayama, Keiichi I Nakayama. EMBO J 2004
579
32

Ubiquitin ligases: cell-cycle control and cancer.
Keiichi I Nakayama, Keiko Nakayama. Nat Rev Cancer 2006
29

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation.
Markus Welcker, Amir Orian, Jianping Jin, Jonathan E Grim, J Wade Harper, Robert N Eisenman, Bruce E Clurman. Proc Natl Acad Sci U S A 2004
655
29

Regulation of hematopoietic stem cell differentiation by a single ubiquitin ligase-substrate complex.
Linsey Reavie, Giusy Della Gatta, Kelly Crusio, Beatriz Aranda-Orgilles, Shannon M Buckley, Benjamin Thompson, Eugine Lee, Jie Gao, Andrea L Bredemeyer, Beth A Helmink,[...]. Nat Immunol 2010
87
31

Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene.
Jian-Hua Mao, Jesus Perez-Losada, Di Wu, Reyno Delrosario, Ryosuke Tsunematsu, Keiichi I Nakayama, Ken Brown, Sheila Bryson, Allan Balmain. Nature 2004
307
26

The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability.
Bryan King, Thomas Trimarchi, Linsey Reavie, Luyao Xu, Jasper Mullenders, Panagiotis Ntziachristos, Beatriz Aranda-Orgilles, Arianne Perez-Garcia, Junwei Shi, Christopher Vakoc,[...]. Cell 2013
223
26

Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7.
Ingrid E Wertz, Saritha Kusam, Cynthia Lam, Toru Okamoto, Wendy Sandoval, Daniel J Anderson, Elizabeth Helgason, James A Ernst, Mike Eby, Jinfeng Liu,[...]. Nature 2011
578
25

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase.
D M Koepp, L K Schaefer, X Ye, K Keyomarsi, C Chu, J W Harper, S J Elledge. Science 2001
629
25

Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development.
Ryosuke Tsunematsu, Keiko Nakayama, Yuichi Oike, Masaaki Nishiyama, Noriko Ishida, Shigetsugu Hatakeyama, Yasumasa Bessho, Ryoichiro Kageyama, Toshio Suda, Keiichi I Nakayama. J Biol Chem 2004
204
25

FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation.
Roya Babaei-Jadidi, Ningning Li, Anas Saadeddin, Bradley Spencer-Dene, Anett Jandke, Belal Muhammad, ElSayed E Ibrahim, Ranjithmenon Muraleedharan, Mohammed Abuzinadah, Hayley Davis,[...]. J Exp Med 2011
133
25

Ablation of Fbxw7 eliminates leukemia-initiating cells by preventing quiescence.
Shoichiro Takeishi, Akinobu Matsumoto, Ichiro Onoyama, Kazuhito Naka, Atsushi Hirao, Keiichi I Nakayama. Cancer Cell 2013
115
24

The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia.
Benjamin J Thompson, Silvia Buonamici, Maria Luisa Sulis, Teresa Palomero, Tomas Vilimas, Giuseppe Basso, Adolfo Ferrando, Iannis Aifantis. J Exp Med 2007
354
23

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
Jennifer O'Neil, Jonathan Grim, Peter Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James Hardwick, Markus Welcker, Jules P Meijerink, Rob Pieters,[...]. J Exp Med 2007
504
22

Fbxw7-dependent degradation of Notch is required for control of "stemness" and neuronal-glial differentiation in neural stem cells.
Akinobu Matsumoto, Ichiro Onoyama, Takehiko Sunabori, Ryoichiro Kageyama, Hideyuki Okano, Keiichi I Nakayama. J Biol Chem 2011
81
27

Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein.
Michael T Tetzlaff, Wei Yu, Mamie Li, Pumin Zhang, Milton Finegold, Kathleen Mahon, J Wade Harper, Robert J Schwartz, Stephen J Elledge. Proc Natl Acad Sci U S A 2004
203
21

F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor.
Rocio Sancho, Anett Jandke, Hayley Davis, Markus E Diefenbacher, Ian Tomlinson, Axel Behrens. Gastroenterology 2010
94
22

Regulation of c-Myc ubiquitination controls chronic myelogenous leukemia initiation and progression.
Linsey Reavie, Shannon M Buckley, Evangelia Loizou, Shoichiro Takeishi, Beatriz Aranda-Orgilles, Delphine Ndiaye-Lobry, Omar Abdel-Wahab, Sherif Ibrahim, Keiichi I Nakayama, Iannis Aifantis. Cancer Cell 2013
85
24

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line.
H Strohmaier, C H Spruck, P Kaiser, K A Won, O Sangfelt, S I Reed. Nature 2001
490
20

FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression.
Jian-Hua Mao, Il-Jin Kim, Di Wu, Joan Climent, Hio Chung Kang, Reyno DelRosario, Allan Balmain. Science 2008
311
19

Inactivation of hCDC4 can cause chromosomal instability.
Harith Rajagopalan, Prasad V Jallepalli, Carlo Rago, Victor E Velculescu, Kenneth W Kinzler, Bert Vogelstein, Christoph Lengauer. Nature 2004
440
19

Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun.
Joerg D Hoeck, Anett Jandke, Sophia M Blake, Emma Nye, Bradley Spencer-Dene, Sebastian Brandner, Axel Behrens. Nat Neurosci 2010
130
18

Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liver.
Ichiro Onoyama, Atsushi Suzuki, Akinobu Matsumoto, Kengo Tomita, Hideki Katagiri, Yuichi Oike, Keiko Nakayama, Keiichi I Nakayama. J Clin Invest 2011
83
21

The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling.
Abdolrahman S Nateri, Lluís Riera-Sans, Clive Da Costa, Axel Behrens. Science 2004
300
17

The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase.
Wenyi Wei, Jianping Jin, Susanne Schlisio, J Wade Harper, William G Kaelin. Cancer Cell 2005
321
17

RING domain E3 ubiquitin ligases.
Raymond J Deshaies, Claudio A P Joazeiro. Annu Rev Biochem 2009
17

Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor.
N Gupta-Rossi, O Le Bail, H Gonen, C Brou, F Logeat, E Six, A Ciechanover, A Israël. J Biol Chem 2001
297
16

Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication.
K Nakayama, H Nagahama, Y A Minamishima, M Matsumoto, I Nakamichi, K Kitagawa, M Shirane, R Tsunematsu, T Tsukiyama, N Ishida,[...]. EMBO J 2000
609
16

Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities.
Ryan J Davis, Markus Welcker, Bruce E Clurman. Cancer Cell 2014
238
16

hCDC4 gene mutations in endometrial cancer.
Charles H Spruck, Heimo Strohmaier, Olle Sangfelt, Hannes M Müller, Michael Hubalek, Elisabeth Müller-Holzner, Christian Marth, Martin Widschwendter, Steven I Reed. Cancer Res 2002
229
15

Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases.
Bing Hao, Stephanie Oehlmann, Mathew E Sowa, J Wade Harper, Nikola P Pavletich. Mol Cell 2007
334
15

Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase.
Sang-Hyun Min, Alan W Lau, Tae Ho Lee, Hiroyuki Inuzuka, Shuo Wei, Pengyu Huang, Shavali Shaik, Daniel Yenhong Lee, Greg Finn, Martin Balastik,[...]. Mol Cell 2012
119
15

Roles of F-box proteins in cancer.
Zhiwei Wang, Pengda Liu, Hiroyuki Inuzuka, Wenyi Wei. Nat Rev Cancer 2014
306
15


hCDC4b, a regulator of cyclin E, as a direct transcriptional target of p53.
Takashi Kimura, Mitsukazu Gotoh, Yusuke Nakamura, Hirofumi Arakawa. Cancer Sci 2003
94
14

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Andrew P Weng, Adolfo A Ferrando, Woojoong Lee, John P Morris, Lewis B Silverman, Cheryll Sanchez-Irizarry, Stephen C Blacklow, A Thomas Look, Jon C Aster. Science 2004
14

A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size.
Markus Welcker, Amir Orian, Jonathan E Grim, Robert N Eisenman, Bruce E Clurman. Curr Biol 2004
237
14

c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation.
Anne Wilson, Mark J Murphy, Thordur Oskarsson, Konstantinos Kaloulis, Michael D Bettess, Gabriela M Oser, Anne-Catherine Pasche, Christian Knabenhans, H Robson Macdonald, Andreas Trumpp. Genes Dev 2004
548
14


Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma.
Luca Busino, Scott E Millman, Luigi Scotto, Christos A Kyratsous, Venkatesha Basrur, Owen O'Connor, Alexander Hoffmann, Kojo S Elenitoba-Johnson, Michele Pagano. Nat Cell Biol 2012
136
14

Tumor suppressor functions of FBW7 in cancer development and progression.
Zhiwei Wang, Hiroyuki Inuzuka, Jiateng Zhong, Lixin Wan, Hidefumi Fukushima, Fazlul H Sarkar, Wenyi Wei. FEBS Lett 2012
128
14

Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer.
Shahab Akhoondi, Linda Lindström, Martin Widschwendter, Martin Corcoran, Jonas Bergh, Charles Spruck, Dan Grandér, Olle Sangfelt. Breast Cancer Res 2010
61
21

Fbw7 and p53 cooperatively suppress advanced and chromosomally unstable intestinal cancer.
Jonathan E Grim, Sue E Knoblaugh, Katherine A Guthrie, Amanda Hagar, Jherek Swanger, Jessica Hespelt, Jeffrey J Delrow, Tom Small, William M Grady, Keiichi I Nakayama,[...]. Mol Cell Biol 2012
63
20

Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression.
Chia-Hsin Chan, John Kenneth Morrow, Chien-Feng Li, Yuan Gao, Guoxiang Jin, Asad Moten, Loren J Stagg, John E Ladbury, Zhen Cai, Dazhi Xu,[...]. Cell 2013
262
13

Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers.
Richard S Maser, Bhudipa Choudhury, Peter J Campbell, Bin Feng, Kwok-Kin Wong, Alexei Protopopov, Jennifer O'Neil, Alejandro Gutierrez, Elena Ivanova, Ilana Perna,[...]. Nature 2007
301
12

The E3 ubiquitin ligase c-Cbl restricts development and functions of hematopoietic stem cells.
Chozhavendan Rathinam, Christine B F Thien, Wallace Y Langdon, Hua Gu, Richard A Flavell. Genes Dev 2008
84
14


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.