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Times Cited: 1083
Times Cited: 1083
Times Cited
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Similarity
Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1.
Christopher I Amos, Xifeng Wu, Peter Broderick, Ivan P Gorlov, Jian Gu, Timothy Eisen, Qiong Dong, Qing Zhang, Xiangjun Gu, Jayaram Vijayakrishnan,[...]. Nat Genet 2008
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A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25.
Rayjean J Hung, James D McKay, Valerie Gaborieau, Paolo Boffetta, Mia Hashibe, David Zaridze, Anush Mukeria, Neonilia Szeszenia-Dabrowska, Jolanta Lissowska, Peter Rudnai,[...]. Nature 2008
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Genome-wide meta-analyses identify multiple loci associated with smoking behavior.
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Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.
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Variants in nicotinic receptors and risk for nicotine dependence.
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Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs.
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Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.
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Habenular α5 nicotinic receptor subunit signalling controls nicotine intake.
Christie D Fowler, Qun Lu, Paul M Johnson, Michael J Marks, Paul J Kenny. Nature 2011
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Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.
Nancy L Saccone, Robert C Culverhouse, Tae-Hwi Schwantes-An, Dale S Cannon, Xiangning Chen, Sven Cichon, Ina Giegling, Shizhong Han, Younghun Han, Kaisu Keskitalo-Vuokko,[...]. PLoS Genet 2010
Nancy L Saccone, Robert C Culverhouse, Tae-Hwi Schwantes-An, Dale S Cannon, Xiangning Chen, Sven Cichon, Ina Giegling, Shizhong Han, Younghun Han, Kaisu Keskitalo-Vuokko,[...]. PLoS Genet 2010
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Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking.
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Meta-analysis and imputation refines the association of 15q25 with smoking quantity.
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Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
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Novel genes identified in a high-density genome wide association study for nicotine dependence.
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Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals.
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Aversion to nicotine is regulated by the balanced activity of β4 and α5 nicotinic receptor subunits in the medial habenula.
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The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.
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9
Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence.
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Nicotinic receptors in the habenulo-interpeduncular system are necessary for nicotine withdrawal in mice.
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Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
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Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci.
A Mesut Erzurumluoglu, Mengzhen Liu, Victoria E Jackson, Daniel R Barnes, Gargi Datta, Carl A Melbourne, Robin Young, Chiara Batini, Praveen Surendran, Tao Jiang,[...]. Mol Psychiatry 2020
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PLINK: a tool set for whole-genome association and population-based linkage analyses.
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A meta-analysis of estimated genetic and environmental effects on smoking behavior in male and female adult twins.
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Principal components analysis corrects for stratification in genome-wide association studies.
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Crucial role of nicotinic α5 subunit variants for Ca2+ fluxes in ventral midbrain neurons.
Miriam Sciaccaluga, Claudia Moriconi, Katiuscia Martinello, Myriam Catalano, Isabel Bermudez, Jerry A Stitzel, Uwe Maskos, Sergio Fucile. FASEB J 2015
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CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis--a meta-analysis.
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Li-Shiun Chen, Rayjean J Hung, Timothy Baker, Amy Horton, Rob Culverhouse, Nancy Saccone, Iona Cheng, Bo Deng, Younghun Han, Helen M Hansen,[...]. J Natl Cancer Inst 2015
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Second-generation PLINK: rising to the challenge of larger and richer datasets.
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An atlas of genetic correlations across human diseases and traits.
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8
A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction.
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Functional contributions of alpha5 subunit to neuronal acetylcholine receptor channels.
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GCTA: a tool for genome-wide complex trait analysis.
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7
Acetylcholine receptor (AChR) α5 subunit variant associated with risk for nicotine dependence and lung cancer reduces (α4β2)₂α5 AChR function.
Alexander Kuryatov, Wade Berrettini, Jon Lindstrom. Mol Pharmacol 2011
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7
Nicotine consumption is regulated by a human polymorphism in dopamine neurons.
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Nicotine addiction and nicotinic receptors: lessons from genetically modified mice.
Jean-Pierre Changeux. Nat Rev Neurosci 2010
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Interplay of genetic risk factors (CHRNA5-CHRNA3-CHRNB4) and cessation treatments in smoking cessation success.
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The habenulo-interpeduncular pathway in nicotine aversion and withdrawal.
Beatriz Antolin-Fontes, Jessica L Ables, Andreas Görlich, Inés Ibañez-Tallon. Neuropharmacology 2015
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Genetic variants on 15q25.1, smoking, and lung cancer: an assessment of mediation and interaction.
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7
Genome-wide meta-analyses of smoking behaviors in African Americans.
S P David, A Hamidovic, G K Chen, A W Bergen, J Wessel, J L Kasberger, W M Brown, S Petruzella, E L Thacker, Y Kim,[...]. Transl Psychiatry 2012
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Habenula "cholinergic" neurons co-release glutamate and acetylcholine and activate postsynaptic neurons via distinct transmission modes.
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Differential expression and function of nicotinic acetylcholine receptors in subdivisions of medial habenula.
Pei-Yu Shih, Staci E Engle, Gyeon Oh, Purnima Deshpande, Nyssa L Puskar, Henry A Lester, Ryan M Drenan. J Neurosci 2014
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8
Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.
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Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes.
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CHRNB3 is more strongly associated with Fagerström test for cigarette dependence-based nicotine dependence than cigarettes per day: phenotype definition changes genome-wide association studies results.
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The UK Biobank resource with deep phenotyping and genomic data.
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Association of the CHRNA5-A3-B4 gene cluster with heaviness of smoking: a meta-analysis.
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Rodent habenulo-interpeduncular pathway expresses a large variety of uncommon nAChR subtypes, but only the alpha3beta4* and alpha3beta3beta4* subtypes mediate acetylcholine release.
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A Decade of GWAS Results in Lung Cancer.
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Genome-wide and candidate gene association study of cigarette smoking behaviors.
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A CHRNA5 Smoking Risk Variant Decreases the Aversive Effects of Nicotine in Humans.
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13
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.