Patricia Cassina, Adriana Cassina, Mariana Pehar, Raquel Castellanos, Mandi Gandelman, Andrés de León, Kristine M Robinson, Ronald P Mason, Joseph S Beckman, Luis Barbeito, Rafael Radi. J Neurosci 2008
Times Cited: 220
Times Cited: 220
Times Cited
Times Co-cited
Similarity
Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons.
Makiko Nagai, Diane B Re, Tetsuya Nagata, Alcmène Chalazonitis, Thomas M Jessell, Hynek Wichterle, Serge Przedborski. Nat Neurosci 2007
Makiko Nagai, Diane B Re, Tetsuya Nagata, Alcmène Chalazonitis, Thomas M Jessell, Hynek Wichterle, Serge Przedborski. Nat Neurosci 2007
44
Astrocytes from familial and sporadic ALS patients are toxic to motor neurons.
Amanda M Haidet-Phillips, Mark E Hester, Carlos J Miranda, Kathrin Meyer, Lyndsey Braun, Ashley Frakes, SungWon Song, Shibi Likhite, Matthew J Murtha, Kevin D Foust,[...]. Nat Biotechnol 2011
Amanda M Haidet-Phillips, Mark E Hester, Carlos J Miranda, Kathrin Meyer, Lyndsey Braun, Ashley Frakes, SungWon Song, Shibi Likhite, Matthew J Murtha, Kevin D Foust,[...]. Nat Biotechnol 2011
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Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis.
Koji Yamanaka, Seung Joo Chun, Severine Boillee, Noriko Fujimori-Tonou, Hirofumi Yamashita, David H Gutmann, Ryosuke Takahashi, Hidemi Misawa, Don W Cleveland. Nat Neurosci 2008
Koji Yamanaka, Seung Joo Chun, Severine Boillee, Noriko Fujimori-Tonou, Hirofumi Yamashita, David H Gutmann, Ryosuke Takahashi, Hidemi Misawa, Don W Cleveland. Nat Neurosci 2008
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Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model.
Francesco Paolo Di Giorgio, Monica A Carrasco, Michelle C Siao, Tom Maniatis, Kevin Eggan. Nat Neurosci 2007
Francesco Paolo Di Giorgio, Monica A Carrasco, Michelle C Siao, Tom Maniatis, Kevin Eggan. Nat Neurosci 2007
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Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells.
Maria C N Marchetto, Alysson R Muotri, Yangling Mu, Alan M Smith, Gabriela G Cezar, Fred H Gage. Cell Stem Cell 2008
Maria C N Marchetto, Alysson R Muotri, Yangling Mu, Alan M Smith, Gabriela G Cezar, Fred H Gage. Cell Stem Cell 2008
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Dysregulation of astrocyte-motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis.
Laura Ferraiuolo, Adrian Higginbottom, Paul R Heath, Sian Barber, David Greenald, Janine Kirby, Pamela J Shaw. Brain 2011
Laura Ferraiuolo, Adrian Higginbottom, Paul R Heath, Sian Barber, David Greenald, Janine Kirby, Pamela J Shaw. Brain 2011
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Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo.
Sophia T Papadeas, Sarah E Kraig, Colin O'Banion, Angelo C Lepore, Nicholas J Maragakis. Proc Natl Acad Sci U S A 2011
Sophia T Papadeas, Sarah E Kraig, Colin O'Banion, Angelo C Lepore, Nicholas J Maragakis. Proc Natl Acad Sci U S A 2011
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Neurotoxic reactive astrocytes are induced by activated microglia.
Shane A Liddelow, Kevin A Guttenplan, Laura E Clarke, Frederick C Bennett, Christopher J Bohlen, Lucas Schirmer, Mariko L Bennett, Alexandra E Münch, Won-Suk Chung, Todd C Peterson,[...]. Nature 2017
Shane A Liddelow, Kevin A Guttenplan, Laura E Clarke, Frederick C Bennett, Christopher J Bohlen, Lucas Schirmer, Mariko L Bennett, Alexandra E Münch, Won-Suk Chung, Todd C Peterson,[...]. Nature 2017
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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis.
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20
Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS).
David S Howland, Jian Liu, Yijin She, Beth Goad, Nicholas J Maragakis, Benjamin Kim, Jamie Erickson, John Kulik, Lisa DeVito, George Psaltis,[...]. Proc Natl Acad Sci U S A 2002
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Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond.
Hristelina Ilieva, Magdalini Polymenidou, Don W Cleveland. J Cell Biol 2009
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Onset and progression in inherited ALS determined by motor neurons and microglia.
Séverine Boillée, Koji Yamanaka, Christian S Lobsiger, Neal G Copeland, Nancy A Jenkins, George Kassiotis, George Kollias, Don W Cleveland. Science 2006
Séverine Boillée, Koji Yamanaka, Christian S Lobsiger, Neal G Copeland, Nancy A Jenkins, George Kassiotis, George Kollias, Don W Cleveland. Science 2006
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Necroptosis drives motor neuron death in models of both sporadic and familial ALS.
Diane B Re, Virginia Le Verche, Changhao Yu, Mackenzie W Amoroso, Kristin A Politi, Sudarshan Phani, Burcin Ikiz, Lucas Hoffmann, Martijn Koolen, Tetsuya Nagata,[...]. Neuron 2014
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19
Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS.
Kathrin Meyer, Laura Ferraiuolo, Carlos J Miranda, Shibi Likhite, Sohyun McElroy, Samantha Renusch, Dara Ditsworth, Clotilde Lagier-Tourenne, Richard A Smith, John Ravits,[...]. Proc Natl Acad Sci U S A 2014
Kathrin Meyer, Laura Ferraiuolo, Carlos J Miranda, Shibi Likhite, Sohyun McElroy, Samantha Renusch, Dara Ditsworth, Clotilde Lagier-Tourenne, Richard A Smith, John Ravits,[...]. Proc Natl Acad Sci U S A 2014
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Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation.
Francesco Paolo Di Giorgio, Gabriella L Boulting, Samuel Bobrowicz, Kevin C Eggan. Cell Stem Cell 2008
Francesco Paolo Di Giorgio, Gabriella L Boulting, Samuel Bobrowicz, Kevin C Eggan. Cell Stem Cell 2008
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Neuroprotective effects of the mitochondria-targeted antioxidant MitoQ in a model of inherited amyotrophic lateral sclerosis.
Ernesto Miquel, Adriana Cassina, Laura Martínez-Palma, José M Souza, Carmen Bolatto, Sebastián Rodríguez-Bottero, Angela Logan, Robin A J Smith, Michael P Murphy, Luis Barbeito,[...]. Free Radic Biol Med 2014
Ernesto Miquel, Adriana Cassina, Laura Martínez-Palma, José M Souza, Carmen Bolatto, Sebastián Rodríguez-Bottero, Angela Logan, Robin A J Smith, Michael P Murphy, Luis Barbeito,[...]. Free Radic Biol Med 2014
20
Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice.
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ALS: a disease of motor neurons and their nonneuronal neighbors.
Séverine Boillée, Christine Vande Velde, Don W Cleveland. Neuron 2006
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17
Astrocyte loss of mutant SOD1 delays ALS disease onset and progression in G85R transgenic mice.
Lijun Wang, David H Gutmann, Raymond P Roos. Hum Mol Genet 2011
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Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis.
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16
Phenotypically aberrant astrocytes that promote motoneuron damage in a model of inherited amyotrophic lateral sclerosis.
Pablo Díaz-Amarilla, Silvia Olivera-Bravo, Emiliano Trias, Andrea Cragnolini, Laura Martínez-Palma, Patricia Cassina, Joseph Beckman, Luis Barbeito. Proc Natl Acad Sci U S A 2011
Pablo Díaz-Amarilla, Silvia Olivera-Bravo, Emiliano Trias, Andrea Cragnolini, Laura Martínez-Palma, Patricia Cassina, Joseph Beckman, Luis Barbeito. Proc Natl Acad Sci U S A 2011
15
Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease.
Angelo C Lepore, Britta Rauck, Christine Dejea, Andrea C Pardo, Mahendra S Rao, Jeffrey D Rothstein, Nicholas J Maragakis. Nat Neurosci 2008
Angelo C Lepore, Britta Rauck, Christine Dejea, Andrea C Pardo, Mahendra S Rao, Jeffrey D Rothstein, Nicholas J Maragakis. Nat Neurosci 2008
14
Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation.
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14
Modulation of astrocytic mitochondrial function by dichloroacetate improves survival and motor performance in inherited amyotrophic lateral sclerosis.
Ernesto Miquel, Adriana Cassina, Laura Martínez-Palma, Carmen Bolatto, Emiliano Trías, Mandi Gandelman, Rafael Radi, Luis Barbeito, Patricia Cassina. PLoS One 2012
Ernesto Miquel, Adriana Cassina, Laura Martínez-Palma, Carmen Bolatto, Emiliano Trías, Mandi Gandelman, Rafael Radi, Luis Barbeito, Patricia Cassina. PLoS One 2012
20
13
Sporadic ALS Astrocytes Induce Neuronal Degeneration In Vivo.
Kun Qian, Hailong Huang, Andrew Peterson, Baoyang Hu, Nicholas J Maragakis, Guo-Li Ming, Hong Chen, Su-Chun Zhang. Stem Cell Reports 2017
Kun Qian, Hailong Huang, Andrew Peterson, Baoyang Hu, Nicholas J Maragakis, Guo-Li Ming, Hong Chen, Su-Chun Zhang. Stem Cell Reports 2017
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Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis.
Marcelo R Vargas, Delinda A Johnson, Daniel W Sirkis, Albee Messing, Jeffrey A Johnson. J Neurosci 2008
Marcelo R Vargas, Delinda A Johnson, Daniel W Sirkis, Albee Messing, Jeffrey A Johnson. J Neurosci 2008
12
Genomic analysis of reactive astrogliosis.
Jennifer L Zamanian, Lijun Xu, Lynette C Foo, Navid Nouri, Lu Zhou, Rona G Giffard, Ben A Barres. J Neurosci 2012
Jennifer L Zamanian, Lijun Xu, Lynette C Foo, Navid Nouri, Lu Zhou, Rona G Giffard, Ben A Barres. J Neurosci 2012
12
Focal degeneration of astrocytes in amyotrophic lateral sclerosis.
D Rossi, L Brambilla, C F Valori, C Roncoroni, A Crugnola, T Yokota, D E Bredesen, A Volterra. Cell Death Differ 2008
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12
Increased glutathione biosynthesis by Nrf2 activation in astrocytes prevents p75NTR-dependent motor neuron apoptosis.
Marcelo R Vargas, Mariana Pehar, Patricia Cassina, Joseph S Beckman, Luis Barbeito. J Neurochem 2006
Marcelo R Vargas, Mariana Pehar, Patricia Cassina, Joseph S Beckman, Luis Barbeito. J Neurochem 2006
12
ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.
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12
Abnormal intracellular calcium signaling and SNARE-dependent exocytosis contributes to SOD1G93A astrocyte-mediated toxicity in amyotrophic lateral sclerosis.
Hibiki Kawamata, Seng Kah Ng, Natalia Diaz, Suzanne Burstein, Lydie Morel, Alexandra Osgood, Brittany Sider, Haruki Higashimori, Philip G Haydon, Giovanni Manfredi,[...]. J Neurosci 2014
Hibiki Kawamata, Seng Kah Ng, Natalia Diaz, Suzanne Burstein, Lydie Morel, Alexandra Osgood, Brittany Sider, Haruki Higashimori, Philip G Haydon, Giovanni Manfredi,[...]. J Neurosci 2014
21
Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis.
Ashley E Frakes, Laura Ferraiuolo, Amanda M Haidet-Phillips, Leah Schmelzer, Lyndsey Braun, Carlos J Miranda, Katherine J Ladner, Adam K Bevan, Kevin D Foust, Jonathan P Godbout,[...]. Neuron 2014
Ashley E Frakes, Laura Ferraiuolo, Amanda M Haidet-Phillips, Leah Schmelzer, Lyndsey Braun, Carlos J Miranda, Katherine J Ladner, Adam K Bevan, Kevin D Foust, Jonathan P Godbout,[...]. Neuron 2014
12
Connexin 43 in astrocytes contributes to motor neuron toxicity in amyotrophic lateral sclerosis.
Akshata A Almad, Arpitha Doreswamy, Sarah K Gross, Jean-Philippe Richard, Yuqing Huo, Norman Haughey, Nicholas J Maragakis. Glia 2016
Akshata A Almad, Arpitha Doreswamy, Sarah K Gross, Jean-Philippe Richard, Yuqing Huo, Norman Haughey, Nicholas J Maragakis. Glia 2016
15
Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity.
Philip Van Damme, Elke Bogaert, Maarten Dewil, Nicole Hersmus, Dora Kiraly, Wendy Scheveneels, Ilse Bockx, Dries Braeken, Nathalie Verpoorten, Kristien Verhoeven,[...]. Proc Natl Acad Sci U S A 2007
Philip Van Damme, Elke Bogaert, Maarten Dewil, Nicole Hersmus, Dora Kiraly, Wendy Scheveneels, Ilse Bockx, Dries Braeken, Nathalie Verpoorten, Kristien Verhoeven,[...]. Proc Natl Acad Sci U S A 2007
12
Expression of ALS-linked TDP-43 mutant in astrocytes causes non-cell-autonomous motor neuron death in rats.
Jianbin Tong, Cao Huang, Fangfang Bi, Qinxue Wu, Bo Huang, Xionghao Liu, Fang Li, Hongxia Zhou, Xu-Gang Xia. EMBO J 2013
Jianbin Tong, Cao Huang, Fangfang Bi, Qinxue Wu, Bo Huang, Xionghao Liu, Fang Li, Hongxia Zhou, Xu-Gang Xia. EMBO J 2013
12
Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy.
Andrea Serio, Bilada Bilican, Sami J Barmada, Dale Michael Ando, Chen Zhao, Rick Siller, Karen Burr, Ghazal Haghi, David Story, Agnes Lumi Nishimura,[...]. Proc Natl Acad Sci U S A 2013
Andrea Serio, Bilada Bilican, Sami J Barmada, Dale Michael Ando, Chen Zhao, Rick Siller, Karen Burr, Ghazal Haghi, David Story, Agnes Lumi Nishimura,[...]. Proc Natl Acad Sci U S A 2013
12
Astrocyte-derived TGF-β1 accelerates disease progression in ALS mice by interfering with the neuroprotective functions of microglia and T cells.
Fumito Endo, Okiru Komine, Noriko Fujimori-Tonou, Masahisa Katsuno, Shijie Jin, Seiji Watanabe, Gen Sobue, Mari Dezawa, Tony Wyss-Coray, Koji Yamanaka. Cell Rep 2015
Fumito Endo, Okiru Komine, Noriko Fujimori-Tonou, Masahisa Katsuno, Shijie Jin, Seiji Watanabe, Gen Sobue, Mari Dezawa, Tony Wyss-Coray, Koji Yamanaka. Cell Rep 2015
12
12
12
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS.
Mariely DeJesus-Hernandez, Ian R Mackenzie, Bradley F Boeve, Adam L Boxer, Matt Baker, Nicola J Rutherford, Alexandra M Nicholson, NiCole A Finch, Heather Flynn, Jennifer Adamson,[...]. Neuron 2011
Mariely DeJesus-Hernandez, Ian R Mackenzie, Bradley F Boeve, Adam L Boxer, Matt Baker, Nicola J Rutherford, Alexandra M Nicholson, NiCole A Finch, Heather Flynn, Jennifer Adamson,[...]. Neuron 2011
11
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD.
Alan E Renton, Elisa Majounie, Adrian Waite, Javier Simón-Sánchez, Sara Rollinson, J Raphael Gibbs, Jennifer C Schymick, Hannu Laaksovirta, John C van Swieten, Liisa Myllykangas,[...]. Neuron 2011
Alan E Renton, Elisa Majounie, Adrian Waite, Javier Simón-Sánchez, Sara Rollinson, J Raphael Gibbs, Jennifer C Schymick, Hannu Laaksovirta, John C van Swieten, Liisa Myllykangas,[...]. Neuron 2011
11
Mutant SOD1-expressing astrocytes release toxic factors that trigger motoneuron death by inducing hyperexcitability.
Elsa Fritz, Pamela Izaurieta, Alexandra Weiss, Franco R Mir, Patricio Rojas, David Gonzalez, Fabiola Rojas, Robert H Brown, Rodolfo Madrid, Brigitte van Zundert. J Neurophysiol 2013
Elsa Fritz, Pamela Izaurieta, Alexandra Weiss, Franco R Mir, Patricio Rojas, David Gonzalez, Fabiola Rojas, Robert H Brown, Rodolfo Madrid, Brigitte van Zundert. J Neurophysiol 2013
15
Astrocytes expressing mutant SOD1 and TDP43 trigger motoneuron death that is mediated via sodium channels and nitroxidative stress.
Fabiola Rojas, Nicole Cortes, Sebastian Abarzua, Agnieszka Dyrda, Brigitte van Zundert. Front Cell Neurosci 2014
Fabiola Rojas, Nicole Cortes, Sebastian Abarzua, Agnieszka Dyrda, Brigitte van Zundert. Front Cell Neurosci 2014
15
Wildtype motoneurons, ALS-Linked SOD1 mutation and glutamate profoundly modify astrocyte metabolism and lactate shuttling.
Blandine Madji Hounoum, Sylvie Mavel, Emmanuelle Coque, Franck Patin, Patrick Vourc'h, Sylviane Marouillat, Lydie Nadal-Desbarats, Patrick Emond, Philippe Corcia, Christian R Andres,[...]. Glia 2017
Blandine Madji Hounoum, Sylvie Mavel, Emmanuelle Coque, Franck Patin, Patrick Vourc'h, Sylviane Marouillat, Lydie Nadal-Desbarats, Patrick Emond, Philippe Corcia, Christian R Andres,[...]. Glia 2017
37
Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse.
Ye Zhang, Steven A Sloan, Laura E Clarke, Christine Caneda, Colton A Plaza, Paul D Blumenthal, Hannes Vogel, Gary K Steinberg, Michael S B Edwards, Gordon Li,[...]. Neuron 2016
Ye Zhang, Steven A Sloan, Laura E Clarke, Christine Caneda, Colton A Plaza, Paul D Blumenthal, Hannes Vogel, Gary K Steinberg, Michael S B Edwards, Gordon Li,[...]. Neuron 2016
11
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Manuela Neumann, Deepak M Sampathu, Linda K Kwong, Adam C Truax, Matthew C Micsenyi, Thomas T Chou, Jennifer Bruce, Theresa Schuck, Murray Grossman, Christopher M Clark,[...]. Science 2006
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11
A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models.
Giulia E Tyzack, Claire E Hall, Christopher R Sibley, Tomasz Cymes, Serhiy Forostyak, Giulia Carlino, Ione F Meyer, Giampietro Schiavo, Su-Chun Zhang, George M Gibbons,[...]. Nat Commun 2017
Giulia E Tyzack, Claire E Hall, Christopher R Sibley, Tomasz Cymes, Serhiy Forostyak, Giulia Carlino, Ione F Meyer, Giampietro Schiavo, Su-Chun Zhang, George M Gibbons,[...]. Nat Commun 2017
17
Reactive gliosis and the multicellular response to CNS damage and disease.
Joshua E Burda, Michael V Sofroniew. Neuron 2014
Joshua E Burda, Michael V Sofroniew. Neuron 2014
10
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis.
Jemeen Sreedharan, Ian P Blair, Vineeta B Tripathi, Xun Hu, Caroline Vance, Boris Rogelj, Steven Ackerley, Jennifer C Durnall, Kelly L Williams, Emanuele Buratti,[...]. Science 2008
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10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.