Julie Gauthier, Dan Spiegelman, Amélie Piton, Ronald G Lafrenière, Sandra Laurent, Judith St-Onge, Line Lapointe, Fadi F Hamdan, Patrick Cossette, Laurent Mottron, Eric Fombonne, Ridha Joober, Claude Marineau, Pierre Drapeau, Guy A Rouleau. Am J Med Genet B Neuropsychiatr Genet 2009
Times Cited: 232
Times Cited: 232
Times Cited
Times Co-cited
Similarity
Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders.
Christelle M Durand, Catalina Betancur, Tobias M Boeckers, Juergen Bockmann, Pauline Chaste, Fabien Fauchereau, Gudrun Nygren, Maria Rastam, I Carina Gillberg, Henrik Anckarsäter,[...]. Nat Genet 2007
Christelle M Durand, Catalina Betancur, Tobias M Boeckers, Juergen Bockmann, Pauline Chaste, Fabien Fauchereau, Gudrun Nygren, Maria Rastam, I Carina Gillberg, Henrik Anckarsäter,[...]. Nat Genet 2007
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Contribution of SHANK3 mutations to autism spectrum disorder.
Rainald Moessner, Christian R Marshall, James S Sutcliffe, Jennifer Skaug, Dalila Pinto, John Vincent, Lonnie Zwaigenbaum, Bridget Fernandez, Wendy Roberts, Peter Szatmari,[...]. Am J Hum Genet 2007
Rainald Moessner, Christian R Marshall, James S Sutcliffe, Jennifer Skaug, Dalila Pinto, John Vincent, Lonnie Zwaigenbaum, Bridget Fernandez, Wendy Roberts, Peter Szatmari,[...]. Am J Hum Genet 2007
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Shank3 mutant mice display autistic-like behaviours and striatal dysfunction.
João Peça, Cátia Feliciano, Jonathan T Ting, Wenting Wang, Michael F Wells, Talaignair N Venkatraman, Christopher D Lascola, Zhanyan Fu, Guoping Feng. Nature 2011
João Peça, Cátia Feliciano, Jonathan T Ting, Wenting Wang, Michael F Wells, Talaignair N Venkatraman, Christopher D Lascola, Zhanyan Fu, Guoping Feng. Nature 2011
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Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: a gradient of severity in cognitive impairments.
Claire S Leblond, Caroline Nava, Anne Polge, Julie Gauthier, Guillaume Huguet, Serge Lumbroso, Fabienne Giuliano, Coline Stordeur, Christel Depienne, Kevin Mouzat,[...]. PLoS Genet 2014
Claire S Leblond, Caroline Nava, Anne Polge, Julie Gauthier, Guillaume Huguet, Serge Lumbroso, Fabienne Giuliano, Coline Stordeur, Christel Depienne, Kevin Mouzat,[...]. PLoS Genet 2014
52
Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication.
Ozlem Bozdagi, Takeshi Sakurai, Danae Papapetrou, Xiaobin Wang, Dara L Dickstein, Nagahide Takahashi, Yuji Kajiwara, Mu Yang, Adam M Katz, Maria Luisa Scattoni,[...]. Mol Autism 2010
Ozlem Bozdagi, Takeshi Sakurai, Danae Papapetrou, Xiaobin Wang, Dara L Dickstein, Nagahide Takahashi, Yuji Kajiwara, Mu Yang, Adam M Katz, Maria Luisa Scattoni,[...]. Mol Autism 2010
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Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3.
Xiaoming Wang, Portia A McCoy, Ramona M Rodriguiz, Yanzhen Pan, H Shawn Je, Adam C Roberts, Caroline J Kim, Janet Berrios, Jennifer S Colvin, Danielle Bousquet-Moore,[...]. Hum Mol Genet 2011
Xiaoming Wang, Portia A McCoy, Ramona M Rodriguiz, Yanzhen Pan, H Shawn Je, Adam C Roberts, Caroline J Kim, Janet Berrios, Jennifer S Colvin, Danielle Bousquet-Moore,[...]. Hum Mol Genet 2011
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Prevalence of SHANK3 variants in patients with different subtypes of autism spectrum disorders.
Luigi Boccuto, Maria Lauri, Sara M Sarasua, Cindy D Skinner, Daniela Buccella, Alka Dwivedi, Daniela Orteschi, Julianne S Collins, Marcella Zollino, Paola Visconti,[...]. Eur J Hum Genet 2013
Luigi Boccuto, Maria Lauri, Sara M Sarasua, Cindy D Skinner, Daniela Buccella, Alka Dwivedi, Daniela Orteschi, Julianne S Collins, Marcella Zollino, Paola Visconti,[...]. Eur J Hum Genet 2013
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Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation.
Simone Berkel, Christian R Marshall, Birgit Weiss, Jennifer Howe, Ralph Roeth, Ute Moog, Volker Endris, Wendy Roberts, Peter Szatmari, Dalila Pinto,[...]. Nat Genet 2010
Simone Berkel, Christian R Marshall, Birgit Weiss, Jennifer Howe, Ralph Roeth, Ute Moog, Volker Endris, Wendy Roberts, Peter Szatmari, Dalila Pinto,[...]. Nat Genet 2010
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Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin.
S Naisbitt, E Kim, J C Tu, B Xiao, C Sala, J Valtschanoff, R J Weinberg, P F Worley, M Sheng. Neuron 1999
S Naisbitt, E Kim, J C Tu, B Xiao, C Sala, J Valtschanoff, R J Weinberg, P F Worley, M Sheng. Neuron 1999
38
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Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2.
Michael J Schmeisser, Elodie Ey, Stephanie Wegener, Juergen Bockmann, A Vanessa Stempel, Angelika Kuebler, Anna-Lena Janssen, Patrick T Udvardi, Ehab Shiban, Christina Spilker,[...]. Nature 2012
Michael J Schmeisser, Elodie Ey, Stephanie Wegener, Juergen Bockmann, A Vanessa Stempel, Angelika Kuebler, Anna-Lena Janssen, Patrick T Udvardi, Ehab Shiban, Christina Spilker,[...]. Nature 2012
31
SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties.
Kihoon Han, J Lloyd Holder, Christian P Schaaf, Hui Lu, Hongmei Chen, Hyojin Kang, Jianrong Tang, Zhenyu Wu, Shuang Hao, Sau Wai Cheung,[...]. Nature 2013
Kihoon Han, J Lloyd Holder, Christian P Schaaf, Hui Lu, Hongmei Chen, Hyojin Kang, Jianrong Tang, Zhenyu Wu, Shuang Hao, Sau Wai Cheung,[...]. Nature 2013
28
SHANK proteins: roles at the synapse and in autism spectrum disorder.
Patricia Monteiro, Guoping Feng. Nat Rev Neurosci 2017
Patricia Monteiro, Guoping Feng. Nat Rev Neurosci 2017
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SHANK1 Deletions in Males with Autism Spectrum Disorder.
Daisuke Sato, Anath C Lionel, Claire S Leblond, Aparna Prasad, Dalila Pinto, Susan Walker, Irene O'Connor, Carolyn Russell, Irene E Drmic, Fadi F Hamdan,[...]. Am J Hum Genet 2012
Daisuke Sato, Anath C Lionel, Claire S Leblond, Aparna Prasad, Dalila Pinto, Susan Walker, Irene O'Connor, Carolyn Russell, Irene E Drmic, Fadi F Hamdan,[...]. Am J Hum Genet 2012
26
Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1.
Albert Y Hung, Kensuke Futai, Carlo Sala, Juli G Valtschanoff, Jubin Ryu, Mollie A Woodworth, Fleur L Kidd, Clifford C Sung, Tsuyoshi Miyakawa, Mark F Bear,[...]. J Neurosci 2008
Albert Y Hung, Kensuke Futai, Carlo Sala, Juli G Valtschanoff, Jubin Ryu, Mollie A Woodworth, Fleur L Kidd, Clifford C Sung, Tsuyoshi Miyakawa, Mark F Bear,[...]. J Neurosci 2008
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Adult restoration of Shank3 expression rescues selective autistic-like phenotypes.
Yuan Mei, Patricia Monteiro, Yang Zhou, Jin-Ah Kim, Xian Gao, Zhanyan Fu, Guoping Feng. Nature 2016
Yuan Mei, Patricia Monteiro, Yang Zhou, Jin-Ah Kim, Xian Gao, Zhanyan Fu, Guoping Feng. Nature 2016
26
Loss of predominant Shank3 isoforms results in hippocampus-dependent impairments in behavior and synaptic transmission.
Mehreen Kouser, Haley E Speed, Colleen M Dewey, Jeremy M Reimers, Allie J Widman, Natasha Gupta, Shunan Liu, Thomas C Jaramillo, Muhammad Bangash, Bo Xiao,[...]. J Neurosci 2013
Mehreen Kouser, Haley E Speed, Colleen M Dewey, Jeremy M Reimers, Allie J Widman, Natasha Gupta, Shunan Liu, Thomas C Jaramillo, Muhammad Bangash, Bo Xiao,[...]. J Neurosci 2013
25
Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins.
J C Tu, B Xiao, S Naisbitt, J P Yuan, R S Petralia, P Brakeman, A Doan, V K Aakalu, A A Lanahan, M Sheng,[...]. Neuron 1999
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The 22q13.3 Deletion Syndrome (Phelan-McDermid Syndrome).
K Phelan, H E McDermid. Mol Syndromol 2012
K Phelan, H E McDermid. Mol Syndromol 2012
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Functional impact of global rare copy number variation in autism spectrum disorders.
Dalila Pinto, Alistair T Pagnamenta, Lambertus Klei, Richard Anney, Daniele Merico, Regina Regan, Judith Conroy, Tiago R Magalhaes, Catarina Correia, Brett S Abrahams,[...]. Nature 2010
Dalila Pinto, Alistair T Pagnamenta, Lambertus Klei, Richard Anney, Daniele Merico, Regina Regan, Judith Conroy, Tiago R Magalhaes, Catarina Correia, Brett S Abrahams,[...]. Nature 2010
25
Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function.
Hyejung Won, Hye-Ryeon Lee, Heon Yung Gee, Won Mah, Jae-Ick Kim, Jiseok Lee, Seungmin Ha, Changuk Chung, Eun Suk Jung, Yi Sul Cho,[...]. Nature 2012
Hyejung Won, Hye-Ryeon Lee, Heon Yung Gee, Won Mah, Jae-Ick Kim, Jiseok Lee, Seungmin Ha, Changuk Chung, Eun Suk Jung, Yi Sul Cho,[...]. Nature 2012
24
Reduced excitatory neurotransmission and mild autism-relevant phenotypes in adolescent Shank3 null mutant mice.
Mu Yang, Ozlem Bozdagi, Maria Luisa Scattoni, Markus Wöhr, Florence I Roullet, Adam M Katz, Danielle N Abrams, David Kalikhman, Harrison Simon, Leuk Woldeyohannes,[...]. J Neurosci 2012
Mu Yang, Ozlem Bozdagi, Maria Luisa Scattoni, Markus Wöhr, Florence I Roullet, Adam M Katz, Danielle N Abrams, David Kalikhman, Harrison Simon, Leuk Woldeyohannes,[...]. J Neurosci 2012
24
Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism.
Stéphane Jamain, Hélène Quach, Catalina Betancur, Maria Råstam, Catherine Colineaux, I Carina Gillberg, Henrik Soderstrom, Bruno Giros, Marion Leboyer, Christopher Gillberg,[...]. Nat Genet 2003
Stéphane Jamain, Hélène Quach, Catalina Betancur, Maria Råstam, Catherine Colineaux, I Carina Gillberg, Henrik Soderstrom, Bruno Giros, Marion Leboyer, Christopher Gillberg,[...]. Nat Genet 2003
23
De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia.
Julie Gauthier, Nathalie Champagne, Ronald G Lafrenière, Lan Xiong, Dan Spiegelman, Edna Brustein, Mathieu Lapointe, Huashan Peng, Mélanie Côté, Anne Noreau,[...]. Proc Natl Acad Sci U S A 2010
Julie Gauthier, Nathalie Champagne, Ronald G Lafrenière, Lan Xiong, Dan Spiegelman, Edna Brustein, Mathieu Lapointe, Huashan Peng, Mélanie Côté, Anne Noreau,[...]. Proc Natl Acad Sci U S A 2010
22
Communication impairments in mice lacking Shank1: reduced levels of ultrasonic vocalizations and scent marking behavior.
Markus Wöhr, Florence I Roullet, Albert Y Hung, Morgan Sheng, Jacqueline N Crawley. PLoS One 2011
Markus Wöhr, Florence I Roullet, Albert Y Hung, Morgan Sheng, Jacqueline N Crawley. PLoS One 2011
22
An architectural framework that may lie at the core of the postsynaptic density.
Marisa K Baron, Tobias M Boeckers, Bianca Vaida, Salem Faham, Mari Gingery, Michael R Sawaya, Danielle Salyer, Eckart D Gundelfinger, James U Bowie. Science 2006
Marisa K Baron, Tobias M Boeckers, Bianca Vaida, Salem Faham, Mari Gingery, Michael R Sawaya, Danielle Salyer, Eckart D Gundelfinger, James U Bowie. Science 2006
21
Sociability and motor functions in Shank1 mutant mice.
Jill L Silverman, Sarah M Turner, Charlotte L Barkan, Seda S Tolu, Roheeni Saxena, Albert Y Hung, Morgan Sheng, Jacqueline N Crawley. Brain Res 2011
Jill L Silverman, Sarah M Turner, Charlotte L Barkan, Seda S Tolu, Roheeni Saxena, Albert Y Hung, Morgan Sheng, Jacqueline N Crawley. Brain Res 2011
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Molecular characterisation of the 22q13 deletion syndrome supports the role of haploinsufficiency of SHANK3/PROSAP2 in the major neurological symptoms.
H L Wilson, A C C Wong, S R Shaw, W-Y Tse, G A Stapleton, M C Phelan, S Hu, J Marshall, H E McDermid. J Med Genet 2003
H L Wilson, A C C Wong, S R Shaw, W-Y Tse, G A Stapleton, M C Phelan, S Hu, J Marshall, H E McDermid. J Med Genet 2003
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Genetic and functional analyses of SHANK2 mutations suggest a multiple hit model of autism spectrum disorders.
Claire S Leblond, Jutta Heinrich, Richard Delorme, Christian Proepper, Catalina Betancur, Guillaume Huguet, Marina Konyukh, Pauline Chaste, Elodie Ey, Maria Rastam,[...]. PLoS Genet 2012
Claire S Leblond, Jutta Heinrich, Richard Delorme, Christian Proepper, Catalina Betancur, Guillaume Huguet, Marina Konyukh, Pauline Chaste, Elodie Ey, Maria Rastam,[...]. PLoS Genet 2012
20
Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects.
Yang Zhou, Tobias Kaiser, Patrícia Monteiro, Xiangyu Zhang, Marie S Van der Goes, Dongqing Wang, Boaz Barak, Menglong Zeng, Chenchen Li, Congyi Lu,[...]. Neuron 2016
Yang Zhou, Tobias Kaiser, Patrícia Monteiro, Xiangyu Zhang, Marie S Van der Goes, Dongqing Wang, Boaz Barak, Menglong Zeng, Chenchen Li, Congyi Lu,[...]. Neuron 2016
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The emerging role of SHANK genes in neuropsychiatric disorders.
Audrey Guilmatre, Guillaume Huguet, Richard Delorme, Thomas Bourgeron. Dev Neurobiol 2014
Audrey Guilmatre, Guillaume Huguet, Richard Delorme, Thomas Bourgeron. Dev Neurobiol 2014
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Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits.
Olga Peñagarikano, Brett S Abrahams, Edward I Herman, Kellen D Winden, Amos Gdalyahu, Hongmei Dong, Lisa I Sonnenblick, Robin Gruver, Joel Almajano, Anatol Bragin,[...]. Cell 2011
Olga Peñagarikano, Brett S Abrahams, Edward I Herman, Kellen D Winden, Amos Gdalyahu, Hongmei Dong, Lisa I Sonnenblick, Robin Gruver, Joel Almajano, Anatol Bragin,[...]. Cell 2011
17
Autism-associated mutations in ProSAP2/Shank3 impair synaptic transmission and neurexin-neuroligin-mediated transsynaptic signaling.
Magali H Arons, Charlotte J Thynne, Andreas M Grabrucker, Dong Li, Michael Schoen, Juliette E Cheyne, Tobias M Boeckers, Johanna M Montgomery, Craig C Garner. J Neurosci 2012
Magali H Arons, Charlotte J Thynne, Andreas M Grabrucker, Dong Li, Michael Schoen, Juliette E Cheyne, Tobias M Boeckers, Johanna M Montgomery, Craig C Garner. J Neurosci 2012
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Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies.
Andreas M Grabrucker, Michael J Schmeisser, Michael Schoen, Tobias M Boeckers. Trends Cell Biol 2011
Andreas M Grabrucker, Michael J Schmeisser, Michael Schoen, Tobias M Boeckers. Trends Cell Biol 2011
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De novo mutations in schizophrenia implicate synaptic networks.
Menachem Fromer, Andrew J Pocklington, David H Kavanagh, Hywel J Williams, Sarah Dwyer, Padhraig Gormley, Lyudmila Georgieva, Elliott Rees, Priit Palta, Douglas M Ruderfer,[...]. Nature 2014
Menachem Fromer, Andrew J Pocklington, David H Kavanagh, Hywel J Williams, Sarah Dwyer, Padhraig Gormley, Lyudmila Georgieva, Elliott Rees, Priit Palta, Douglas M Ruderfer,[...]. Nature 2014
16
Proline-rich synapse-associated proteins ProSAP1 and ProSAP2 interact with synaptic proteins of the SAPAP/GKAP family.
T M Boeckers, C Winter, K H Smalla, M R Kreutz, J Bockmann, C Seidenbecher, C C Garner, E D Gundelfinger. Biochem Biophys Res Commun 1999
T M Boeckers, C Winter, K H Smalla, M R Kreutz, J Bockmann, C Seidenbecher, C C Garner, E D Gundelfinger. Biochem Biophys Res Commun 1999
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Disruption of the ProSAP2 gene in a t(12;22)(q24.1;q13.3) is associated with the 22q13.3 deletion syndrome.
M C Bonaglia, R Giorda, R Borgatti, G Felisari, C Gagliardi, A Selicorni, O Zuffardi. Am J Hum Genet 2001
M C Bonaglia, R Giorda, R Borgatti, G Felisari, C Gagliardi, A Selicorni, O Zuffardi. Am J Hum Genet 2001
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Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism.
Xiaoming Wang, Alexandra L Bey, Brittany M Katz, Alexandra Badea, Namsoo Kim, Lisa K David, Lara J Duffney, Sunil Kumar, Stephen D Mague, Samuel W Hulbert,[...]. Nat Commun 2016
Xiaoming Wang, Alexandra L Bey, Brittany M Katz, Alexandra Badea, Namsoo Kim, Lisa K David, Lara J Duffney, Sunil Kumar, Stephen D Mague, Samuel W Hulbert,[...]. Nat Commun 2016
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SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients.
Aleksandr Shcheglovitov, Olesya Shcheglovitova, Masayuki Yazawa, Thomas Portmann, Rui Shu, Vittorio Sebastiano, Anna Krawisz, Wendy Froehlich, Jonathan A Bernstein, Joachim F Hallmayer,[...]. Nature 2013
Aleksandr Shcheglovitov, Olesya Shcheglovitova, Masayuki Yazawa, Thomas Portmann, Rui Shu, Vittorio Sebastiano, Anna Krawisz, Wendy Froehlich, Jonathan A Bernstein, Joachim F Hallmayer,[...]. Nature 2013
15
The postsynaptic density proteins Homer and Shank form a polymeric network structure.
Mariko Kato Hayashi, Chunyan Tang, Chiara Verpelli, Radhakrishnan Narayanan, Marissa H Stearns, Rui-Ming Xu, Huilin Li, Carlo Sala, Yasunori Hayashi. Cell 2009
Mariko Kato Hayashi, Chunyan Tang, Chiara Verpelli, Radhakrishnan Narayanan, Marissa H Stearns, Rui-Ming Xu, Huilin Li, Carlo Sala, Yasunori Hayashi. Cell 2009
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Prospective investigation of autism and genotype-phenotype correlations in 22q13 deletion syndrome and SHANK3 deficiency.
Latha Soorya, Alexander Kolevzon, Jessica Zweifach, Teresa Lim, Yuriy Dobry, Lily Schwartz, Yitzchak Frank, A Ting Wang, Guiqing Cai, Elena Parkhomenko,[...]. Mol Autism 2013
Latha Soorya, Alexander Kolevzon, Jessica Zweifach, Teresa Lim, Yuriy Dobry, Lily Schwartz, Yitzchak Frank, A Ting Wang, Guiqing Cai, Elena Parkhomenko,[...]. Mol Autism 2013
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Regulation of dendritic spine morphology and synaptic function by Shank and Homer.
C Sala, V Piëch, N R Wilson, M Passafaro, G Liu, M Sheng. Neuron 2001
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Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2.
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Synaptic, transcriptional and chromatin genes disrupted in autism.
Silvia De Rubeis, Xin He, Arthur P Goldberg, Christopher S Poultney, Kaitlin Samocha, A Erucment Cicek, Yan Kou, Li Liu, Menachem Fromer, Susan Walker,[...]. Nature 2014
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ProSAP/Shank proteins - a family of higher order organizing molecules of the postsynaptic density with an emerging role in human neurological disease.
Tobias M Boeckers, Jürgen Bockmann, Michael R Kreutz, Eckart D Gundelfinger. J Neurochem 2002
Tobias M Boeckers, Jürgen Bockmann, Michael R Kreutz, Eckart D Gundelfinger. J Neurochem 2002
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The contribution of de novo coding mutations to autism spectrum disorder.
Ivan Iossifov, Brian J O'Roak, Stephan J Sanders, Michael Ronemus, Niklas Krumm, Dan Levy, Holly A Stessman, Kali T Witherspoon, Laura Vives, Karynne E Patterson,[...]. Nature 2014
Ivan Iossifov, Brian J O'Roak, Stephan J Sanders, Michael Ronemus, Niklas Krumm, Dan Levy, Holly A Stessman, Kali T Witherspoon, Laura Vives, Karynne E Patterson,[...]. Nature 2014
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SHANK3 mutations identified in autism lead to modification of dendritic spine morphology via an actin-dependent mechanism.
C M Durand, J Perroy, F Loll, D Perrais, L Fagni, T Bourgeron, M Montcouquiol, N Sans. Mol Psychiatry 2012
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Autism genome-wide copy number variation reveals ubiquitin and neuronal genes.
Joseph T Glessner, Kai Wang, Guiqing Cai, Olena Korvatska, Cecilia E Kim, Shawn Wood, Haitao Zhang, Annette Estes, Camille W Brune, Jonathan P Bradfield,[...]. Nature 2009
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14
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.