A citation-based method for searching scientific literature

Hiroki Ishikawa, Glen N Barber. Nature 2008
Times Cited: 1584







List of co-cited articles
896 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.
Lijun Sun, Jiaxi Wu, Fenghe Du, Xiang Chen, Zhijian J Chen. Science 2013
52


Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA.
Jiaxi Wu, Lijun Sun, Xiang Chen, Fenghe Du, Heping Shi, Chuo Chen, Zhijian J Chen. Science 2013
35

The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation.
Bo Zhong, Yan Yang, Shu Li, Yan-Yi Wang, Ying Li, Feici Diao, Caoqi Lei, Xiao He, Lu Zhang, Po Tien,[...]. Immunity 2008
852
33

cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.
Andrea Ablasser, Marion Goldeck, Taner Cavlar, Tobias Deimling, Gregor Witte, Ingo Röhl, Karl-Peter Hopfner, Janos Ludwig, Veit Hornung. Nature 2013
713
28

Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation.
Siqi Liu, Xin Cai, Jiaxi Wu, Qian Cong, Xiang Chen, Tuo Li, Fenghe Du, Junyao Ren, You-Tong Wu, Nick V Grishin,[...]. Science 2015
683
27

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization.
Wenxiang Sun, Yang Li, Lu Chen, Huihui Chen, Fuping You, Xiang Zhou, Yi Zhou, Zhonghe Zhai, Danying Chen, Zhengfan Jiang. Proc Natl Acad Sci U S A 2009
458
26

STING is a direct innate immune sensor of cyclic di-GMP.
Dara L Burdette, Kathryn M Monroe, Katia Sotelo-Troha, Jeff S Iwig, Barbara Eckert, Mamoru Hyodo, Yoshihiro Hayakawa, Russell E Vance. Nature 2011
825
22

STING: infection, inflammation and cancer.
Glen N Barber. Nat Rev Immunol 2015
499
21


Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.
Pu Gao, Manuel Ascano, Yang Wu, Winfried Barchet, Barbara L Gaffney, Thomas Zillinger, Artem A Serganov, Yizhou Liu, Roger A Jones, Gunther Hartmann,[...]. Cell 2013
486
20

Activated STING in a vascular and pulmonary syndrome.
Y Liu, A A Jesus, B Marrero, D Yang, S E Ramsey, G A Montealegre Sanchez, K Tenbrock, H Wittkowski, O Y Jones, H S Kuehn,[...]. N Engl J Med 2014
624
20

Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING.
Xu Zhang, Heping Shi, Jiaxi Wu, Xuewu Zhang, Lijun Sun, Chuo Chen, Zhijian J Chen. Mol Cell 2013
482
19

Structural basis of STING binding with and phosphorylation by TBK1.
Conggang Zhang, Guijun Shang, Xiang Gui, Xuewu Zhang, Xiao-Chen Bai, Zhijian J Chen. Nature 2019
170
19

Activation of STING requires palmitoylation at the Golgi.
Kojiro Mukai, Hiroyasu Konno, Tatsuya Akiba, Takefumi Uemura, Satoshi Waguri, Toshihide Kobayashi, Glen N Barber, Hiroyuki Arai, Tomohiko Taguchi. Nat Commun 2016
179
17

Autophagy induction via STING trafficking is a primordial function of the cGAS pathway.
Xiang Gui, Hui Yang, Tuo Li, Xiaojun Tan, Peiqing Shi, Minghao Li, Fenghe Du, Zhijian J Chen. Nature 2019
241
16

Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects.
Xiao-Dong Li, Jiaxi Wu, Daxing Gao, Hua Wang, Lijun Sun, Zhijian J Chen. Science 2013
585
16

STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors.
Liufu Deng, Hua Liang, Meng Xu, Xuanming Yang, Byron Burnette, Ainhoa Arina, Xiao-Dong Li, Helena Mauceri, Michael Beckett, Thomas Darga,[...]. Immunity 2014
849
16

Cyclic GMP-AMP synthase is activated by double-stranded DNA-induced oligomerization.
Xin Li, Chang Shu, Guanghui Yi, Catherine T Chaton, Catherine L Shelton, Jiasheng Diao, Xiaobing Zuo, C Cheng Kao, Andrew B Herr, Pingwei Li. Immunity 2013
265
15

The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING.
Elie J Diner, Dara L Burdette, Stephen C Wilson, Kathryn M Monroe, Colleen A Kellenberger, Mamoru Hyodo, Yoshihiro Hayakawa, Ming C Hammond, Russell E Vance. Cell Rep 2013
413
15

Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP.
Guijun Shang, Conggang Zhang, Zhijian J Chen, Xiao-Chen Bai, Xuewu Zhang. Nature 2019
138
15

STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.
Seng-Ryong Woo, Mercedes B Fuertes, Leticia Corrales, Stefani Spranger, Michael J Furdyna, Michael Y K Leung, Ryan Duggan, Ying Wang, Glen N Barber, Katherine A Fitzgerald,[...]. Immunity 2014
746
15

Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing.
Qi Chen, Lijun Sun, Zhijian J Chen. Nat Immunol 2016
696
15

Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses.
Daxing Gao, Jiaxi Wu, You-Tong Wu, Fenghe Du, Chukwuemika Aroh, Nan Yan, Lijun Sun, Zhijian J Chen. Science 2013
606
14

Nuclear cGAS suppresses DNA repair and promotes tumorigenesis.
Haipeng Liu, Haiping Zhang, Xiangyang Wu, Dapeng Ma, Juehui Wu, Lin Wang, Yan Jiang, Yiyan Fei, Chenggang Zhu, Rong Tan,[...]. Nature 2018
199
14


Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity.
Leticia Corrales, Laura Hix Glickman, Sarah M McWhirter, David B Kanne, Kelsey E Sivick, George E Katibah, Seng-Ryong Woo, Edward Lemmens, Tamara Banda, Justin J Leong,[...]. Cell Rep 2015
574
13

Inherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestations.
Nadia Jeremiah, Bénédicte Neven, Matteo Gentili, Isabelle Callebaut, Sophia Maschalidi, Marie-Claude Stolzenberg, Nicolas Goudin, Marie-Louis Frémond, Patrick Nitschke, Thierry J Molina,[...]. J Clin Invest 2014
263
13

Signalling strength determines proapoptotic functions of STING.
Muhammet F Gulen, Ute Koch, Simone M Haag, Fabian Schuler, Lionel Apetoh, Andreas Villunger, Freddy Radtke, Andrea Ablasser. Nat Commun 2017
155
13

DNA sensing by the cGAS-STING pathway in health and disease.
Mona Motwani, Scott Pesiridis, Katherine A Fitzgerald. Nat Rev Genet 2019
263
12

Structure-function analysis of STING activation by c[G(2',5')pA(3',5')p] and targeting by antiviral DMXAA.
Pu Gao, Manuel Ascano, Thomas Zillinger, Weiyi Wang, Peihong Dai, Artem A Serganov, Barbara L Gaffney, Stewart Shuman, Roger A Jones, Liang Deng,[...]. Cell 2013
279
12


cGAS surveillance of micronuclei links genome instability to innate immunity.
Karen J Mackenzie, Paula Carroll, Carol-Anne Martin, Olga Murina, Adeline Fluteau, Daniel J Simpson, Nelly Olova, Hannah Sutcliffe, Jacqueline K Rainger, Andrea Leitch,[...]. Nature 2017
569
12

Structural mechanism of cytosolic DNA sensing by cGAS.
Filiz Civril, Tobias Deimling, Carina C de Oliveira Mann, Andrea Ablasser, Manuela Moldt, Gregor Witte, Veit Hornung, Karl-Peter Hopfner. Nature 2013
356
11

Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases.
Daxing Gao, Tuo Li, Xiao-Dong Li, Xiang Chen, Quan-Zhen Li, Mary Wight-Carter, Zhijian J Chen. Proc Natl Acad Sci U S A 2015
306
11

Cytoplasmic chromatin triggers inflammation in senescence and cancer.
Zhixun Dou, Kanad Ghosh, Maria Grazia Vizioli, Jiajun Zhu, Payel Sen, Kirk J Wangensteen, Johayra Simithy, Yemin Lan, Yanping Lin, Zhuo Zhou,[...]. Nature 2017
410
11

STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade.
Juan Fu, David B Kanne, Meredith Leong, Laura Hix Glickman, Sarah M McWhirter, Edward Lemmens, Ken Mechette, Justin J Leong, Peter Lauer, Weiqun Liu,[...]. Sci Transl Med 2015
364
11

Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage.
Gillian Dunphy, Sinéad M Flannery, Jessica F Almine, Dympna J Connolly, Christina Paulus, Kasper L Jønsson, Martin R Jakobsen, Michael M Nevels, Andrew G Bowie, Leonie Unterholzner. Mol Cell 2018
170
11

cGAS in action: Expanding roles in immunity and inflammation.
Andrea Ablasser, Zhijian J Chen. Science 2019
221
10

STING directly activates autophagy to tune the innate immune response.
Dong Liu, Hao Wu, Chenguang Wang, Yanjun Li, Huabin Tian, Sami Siraj, Sheikh Arslan Sehgal, Xiaohui Wang, Jun Wang, Yingli Shang,[...]. Cell Death Differ 2019
88
11

Mitochondrial DNA stress primes the antiviral innate immune response.
A Phillip West, William Khoury-Hanold, Matthew Staron, Michal C Tal, Cristiana M Pineda, Sabine M Lang, Megan Bestwick, Brett A Duguay, Nuno Raimundo, Donna A MacDuff,[...]. Nature 2015
709
10

STING-associated vasculopathy develops independently of IRF3 in mice.
James D Warner, Ricardo A Irizarry-Caro, Brock G Bennion, Teresa L Ai, Amber M Smith, Cathrine A Miner, Tomomi Sakai, Vijay K Gonugunta, Jianjun Wu, Derek J Platt,[...]. J Exp Med 2017
75
13

STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity.
Olivier Demaria, Aude De Gassart, Sanja Coso, Nicolas Gestermann, Jeremy Di Domizio, Lukas Flatz, Olivier Gaide, Olivier Michielin, Patrick Hwu, Tatiana V Petrova,[...]. Proc Natl Acad Sci U S A 2015
216
10

Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response.
Tatsuya Saitoh, Naonobu Fujita, Takuya Hayashi, Keigo Takahara, Takashi Satoh, Hanna Lee, Kohichi Matsunaga, Shun Kageyama, Hiroko Omori, Takeshi Noda,[...]. Proc Natl Acad Sci U S A 2009
485
10

STING Activation by Translocation from the ER Is Associated with Infection and Autoinflammatory Disease.
Nicole Dobbs, Nikolay Burnaevskiy, Didi Chen, Vijay K Gonugunta, Neal M Alto, Nan Yan. Cell Host Microbe 2015
210
10

A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1.
Baoyu Zhao, Fenglei Du, Pengbiao Xu, Chang Shu, Banumathi Sankaran, Samantha L Bell, Mengmeng Liu, Yuanjiu Lei, Xinsheng Gao, Xiaofeng Fu,[...]. Nature 2019
70
14

Design of amidobenzimidazole STING receptor agonists with systemic activity.
Joshi M Ramanjulu, G Scott Pesiridis, Jingsong Yang, Nestor Concha, Robert Singhaus, Shu-Yun Zhang, Jean-Luc Tran, Patrick Moore, Stephanie Lehmann, H Christian Eberl,[...]. Nature 2018
192
10

An orally available non-nucleotide STING agonist with antitumor activity.
Bo-Sheng Pan, Samanthi A Perera, Jennifer A Piesvaux, Jeremy P Presland, Gottfried K Schroeder, Jared N Cumming, B Wesley Trotter, Michael D Altman, Alexei V Buevich, Brandon Cash,[...]. Science 2020
60
16

The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3.
Moritz M Gaidt, Thomas S Ebert, Dhruv Chauhan, Katharina Ramshorn, Francesca Pinci, Sarah Zuber, Fionan O'Duill, Jonathan L Schmid-Burgk, Florian Hoss, Raymund Buhmann,[...]. Cell 2017
193
10

Targeting STING with covalent small-molecule inhibitors.
Simone M Haag, Muhammet F Gulen, Luc Reymond, Antoine Gibelin, Laurence Abrami, Alexiane Decout, Michael Heymann, F Gisou van der Goot, Gerardo Turcatti, Rayk Behrendt,[...]. Nature 2018
210
9


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.