Young Duk Yang, Hawon Cho, Jae Yeon Koo, Min Ho Tak, Yeongyo Cho, Won-Sik Shim, Seung Pyo Park, Jesun Lee, Byeongjun Lee, Byung-Moon Kim, Ramin Raouf, Young Ki Shin, Uhtaek Oh. Nature 2008
Times Cited: 930
Times Cited: 930
Times Cited
Times Co-cited
Similarity
TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity.
Antonella Caputo, Emanuela Caci, Loretta Ferrera, Nicoletta Pedemonte, Cristina Barsanti, Elvira Sondo, Ulrich Pfeffer, Roberto Ravazzolo, Olga Zegarra-Moran, Luis J V Galietta. Science 2008
Antonella Caputo, Emanuela Caci, Loretta Ferrera, Nicoletta Pedemonte, Cristina Barsanti, Elvira Sondo, Ulrich Pfeffer, Roberto Ravazzolo, Olga Zegarra-Moran, Luis J V Galietta. Science 2008
77
Expression cloning of TMEM16A as a calcium-activated chloride channel subunit.
Björn Christian Schroeder, Tong Cheng, Yuh Nung Jan, Lily Yeh Jan. Cell 2008
Björn Christian Schroeder, Tong Cheng, Yuh Nung Jan, Lily Yeh Jan. Cell 2008
74
Structure and function of TMEM16 proteins (anoctamins).
Nicoletta Pedemonte, Luis J V Galietta. Physiol Rev 2014
Nicoletta Pedemonte, Luis J V Galietta. Physiol Rev 2014
34
Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM.
Cristina Paulino, Valeria Kalienkova, Andy K M Lam, Yvonne Neldner, Raimund Dutzler. Nature 2017
Cristina Paulino, Valeria Kalienkova, Andy K M Lam, Yvonne Neldner, Raimund Dutzler. Nature 2017
31
Cryo-EM structures of the TMEM16A calcium-activated chloride channel.
Shangyu Dang, Shengjie Feng, Jason Tien, Christian J Peters, David Bulkley, Marco Lolicato, Jianhua Zhao, Kathrin Zuberbühler, Wenlei Ye, Lijun Qi,[...]. Nature 2017
Shangyu Dang, Shengjie Feng, Jason Tien, Christian J Peters, David Bulkley, Marco Lolicato, Jianhua Zhao, Kathrin Zuberbühler, Wenlei Ye, Lijun Qi,[...]. Nature 2017
29
Calcium-activated chloride channels.
Criss Hartzell, Ilva Putzier, Jorge Arreola. Annu Rev Physiol 2005
Criss Hartzell, Ilva Putzier, Jorge Arreola. Annu Rev Physiol 2005
26
X-ray structure of a calcium-activated TMEM16 lipid scramblase.
Janine D Brunner, Novandy K Lim, Stephan Schenck, Alessia Duerst, Raimund Dutzler. Nature 2014
Janine D Brunner, Novandy K Lim, Stephan Schenck, Alessia Duerst, Raimund Dutzler. Nature 2014
24
Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling.
Adrian Britschgi, Anke Bill, Heike Brinkhaus, Christopher Rothwell, Ieuan Clay, Stephan Duss, Michael Rebhan, Pichai Raman, Chantale T Guy, Kristie Wetzel,[...]. Proc Natl Acad Sci U S A 2013
Adrian Britschgi, Anke Bill, Heike Brinkhaus, Christopher Rothwell, Ieuan Clay, Stephan Duss, Michael Rebhan, Pichai Raman, Chantale T Guy, Kristie Wetzel,[...]. Proc Natl Acad Sci U S A 2013
24
Calcium-dependent phospholipid scrambling by TMEM16F.
Jun Suzuki, Masato Umeda, Peter J Sims, Shigekazu Nagata. Nature 2010
Jun Suzuki, Masato Umeda, Peter J Sims, Shigekazu Nagata. Nature 2010
21
TMEM16A induces MAPK and contributes directly to tumorigenesis and cancer progression.
Umamaheswar Duvvuri, Daniel J Shiwarski, Dong Xiao, Carol Bertrand, Xin Huang, Robert S Edinger, Jason R Rock, Brian D Harfe, Brian J Henson, Karl Kunzelmann,[...]. Cancer Res 2012
Umamaheswar Duvvuri, Daniel J Shiwarski, Dong Xiao, Carol Bertrand, Xin Huang, Robert S Edinger, Jason R Rock, Brian D Harfe, Brian J Henson, Karl Kunzelmann,[...]. Cancer Res 2012
20
The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons.
Hawon Cho, Young Duk Yang, Jesun Lee, Byeongjoon Lee, Tahnbee Kim, Yongwoo Jang, Seung Keun Back, Heung Sik Na, Brian D Harfe, Fan Wang,[...]. Nat Neurosci 2012
Hawon Cho, Young Duk Yang, Jesun Lee, Byeongjoon Lee, Tahnbee Kim, Yongwoo Jang, Seung Keun Back, Heung Sik Na, Brian D Harfe, Fan Wang,[...]. Nat Neurosci 2012
19
TMEM16F forms a Ca2+-activated cation channel required for lipid scrambling in platelets during blood coagulation.
Huanghe Yang, Andrew Kim, Tovo David, Daniel Palmer, Taihao Jin, Jason Tien, Fen Huang, Tong Cheng, Shaun R Coughlin, Yuh Nung Jan,[...]. Cell 2012
Huanghe Yang, Andrew Kim, Tovo David, Daniel Palmer, Taihao Jin, Jason Tien, Fen Huang, Tong Cheng, Shaun R Coughlin, Yuh Nung Jan,[...]. Cell 2012
19
Voltage- and calcium-dependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop.
Qinghuan Xiao, Kuai Yu, Patricia Perez-Cornejo, Yuanyuan Cui, Jorge Arreola, H Criss Hartzell. Proc Natl Acad Sci U S A 2011
Qinghuan Xiao, Kuai Yu, Patricia Perez-Cornejo, Yuanyuan Cui, Jorge Arreola, H Criss Hartzell. Proc Natl Acad Sci U S A 2011
19
Ani9, A Novel Potent Small-Molecule ANO1 Inhibitor with Negligible Effect on ANO2.
Yohan Seo, Ho K Lee, Jinhong Park, Dong-Kyu Jeon, Sungwoo Jo, Minjae Jo, Wan Namkung. PLoS One 2016
Yohan Seo, Ho K Lee, Jinhong Park, Dong-Kyu Jeon, Sungwoo Jo, Minjae Jo, Wan Namkung. PLoS One 2016
20
Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction.
Fen Huang, Hongkang Zhang, Meng Wu, Huanghe Yang, Makoto Kudo, Christian J Peters, Prescott G Woodruff, Owen D Solberg, Matthew L Donne, Xiaozhu Huang,[...]. Proc Natl Acad Sci U S A 2012
Fen Huang, Hongkang Zhang, Meng Wu, Huanghe Yang, Makoto Kudo, Christian J Peters, Prescott G Woodruff, Owen D Solberg, Matthew L Donne, Xiaozhu Huang,[...]. Proc Natl Acad Sci U S A 2012
18
Cryo-EM structures and functional characterization of the murine lipid scramblase TMEM16F.
Carolina Alvadia, Novandy K Lim, Vanessa Clerico Mosina, Gert T Oostergetel, Raimund Dutzler, Cristina Paulino. Elife 2019
Carolina Alvadia, Novandy K Lim, Vanessa Clerico Mosina, Gert T Oostergetel, Raimund Dutzler, Cristina Paulino. Elife 2019
25
Molecular basis of PIP2-dependent regulation of the Ca2+-activated chloride channel TMEM16A.
Son C Le, Zhiguang Jia, Jianhan Chen, Huanghe Yang. Nat Commun 2019
Son C Le, Zhiguang Jia, Jianhan Chen, Huanghe Yang. Nat Commun 2019
50
Known structures and unknown mechanisms of TMEM16 scramblases and channels.
Maria E Falzone, Mattia Malvezzi, Byoung-Cheol Lee, Alessio Accardi. J Gen Physiol 2018
Maria E Falzone, Mattia Malvezzi, Byoung-Cheol Lee, Alessio Accardi. J Gen Physiol 2018
29
Recent advances in TMEM16A: Structure, function, and disease.
Qiushuang Ji, Shuai Guo, Xuzhao Wang, Chunli Pang, Yong Zhan, Yafei Chen, Hailong An. J Cell Physiol 2019
Qiushuang Ji, Shuai Guo, Xuzhao Wang, Chunli Pang, Yong Zhan, Yafei Chen, Hailong An. J Cell Physiol 2019
30
Cell-specific mechanisms of TMEM16A Ca2+-activated chloride channel in cancer.
Hui Wang, Liang Zou, Ke Ma, Jiankun Yu, Huizhe Wu, Minjie Wei, Qinghuan Xiao. Mol Cancer 2017
Hui Wang, Liang Zou, Ke Ma, Jiankun Yu, Huizhe Wu, Minjie Wei, Qinghuan Xiao. Mol Cancer 2017
24
The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.
Simon R Bushell, Ashley C W Pike, Maria E Falzone, Nils J G Rorsman, Chau M Ta, Robin A Corey, Thomas D Newport, John C Christianson, Lara F Scofano, Chitra A Shintre,[...]. Nat Commun 2019
Simon R Bushell, Ashley C W Pike, Maria E Falzone, Nils J G Rorsman, Chau M Ta, Robin A Corey, Thomas D Newport, John C Christianson, Lara F Scofano, Chitra A Shintre,[...]. Nat Commun 2019
30
Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A.
Cristina Paulino, Yvonne Neldner, Andy Km Lam, Valeria Kalienkova, Janine Denise Brunner, Stephan Schenck, Raimund Dutzler. Elife 2017
Cristina Paulino, Yvonne Neldner, Andy Km Lam, Valeria Kalienkova, Janine Denise Brunner, Stephan Schenck, Raimund Dutzler. Elife 2017
16
Studies on expression and function of the TMEM16A calcium-activated chloride channel.
Fen Huang, Jason R Rock, Brian D Harfe, Tong Cheng, Xiaozhu Huang, Yuh Nung Jan, Lily Yeh Jan. Proc Natl Acad Sci U S A 2009
Fen Huang, Jason R Rock, Brian D Harfe, Tong Cheng, Xiaozhu Huang, Yuh Nung Jan, Lily Yeh Jan. Proc Natl Acad Sci U S A 2009
15
TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells.
Wan Namkung, Puay-Wah Phuan, A S Verkman. J Biol Chem 2011
Wan Namkung, Puay-Wah Phuan, A S Verkman. J Biol Chem 2011
15
TMEM16F (Anoctamin 6), an anion channel of delayed Ca(2+) activation.
Søren Grubb, Kristian A Poulsen, Christian Ammitzbøll Juul, Tania Kyed, Thomas K Klausen, Erik Hviid Larsen, Else K Hoffmann. J Gen Physiol 2013
Søren Grubb, Kristian A Poulsen, Christian Ammitzbøll Juul, Tania Kyed, Thomas K Klausen, Erik Hviid Larsen, Else K Hoffmann. J Gen Physiol 2013
16
Phosphatidylinositol 4,5-bisphosphate, cholesterol, and fatty acids modulate the calcium-activated chloride channel TMEM16A (ANO1).
José J De Jesús-Pérez, Silvia Cruz-Rangel, Ángeles E Espino-Saldaña, Ataúlfo Martínez-Torres, Zhiqiang Qu, H Criss Hartzell, Nancy E Corral-Fernandez, Patricia Pérez-Cornejo, Jorge Arreola. Biochim Biophys Acta Mol Cell Biol Lipids 2018
José J De Jesús-Pérez, Silvia Cruz-Rangel, Ángeles E Espino-Saldaña, Ataúlfo Martínez-Torres, Zhiqiang Qu, H Criss Hartzell, Nancy E Corral-Fernandez, Patricia Pérez-Cornejo, Jorge Arreola. Biochim Biophys Acta Mol Cell Biol Lipids 2018
36
Inhibition of TMEM16A expression suppresses growth and invasion in human colorectal cancer cells.
Yujie Sui, Meiyan Sun, Fei Wu, Longfei Yang, Weihua Di, Guizhen Zhang, Lili Zhong, Zhiming Ma, Jinhao Zheng, Xuedong Fang,[...]. PLoS One 2014
Yujie Sui, Meiyan Sun, Fei Wu, Longfei Yang, Weihua Di, Guizhen Zhang, Lili Zhong, Zhiming Ma, Jinhao Zheng, Xuedong Fang,[...]. PLoS One 2014
17
Expression of anoctamin 1/TMEM16A by interstitial cells of Cajal is fundamental for slow wave activity in gastrointestinal muscles.
Sung Jin Hwang, Peter J A Blair, Fiona C Britton, Kate E O'Driscoll, Grant Hennig, Yulia R Bayguinov, Jason R Rock, Brian D Harfe, Kenton M Sanders, Sean M Ward. J Physiol 2009
Sung Jin Hwang, Peter J A Blair, Fiona C Britton, Kate E O'Driscoll, Grant Hennig, Yulia R Bayguinov, Jason R Rock, Brian D Harfe, Kenton M Sanders, Sean M Ward. J Physiol 2009
14
TMEM16B induces chloride currents activated by calcium in mammalian cells.
Simone Pifferi, Michele Dibattista, Anna Menini. Pflugers Arch 2009
Simone Pifferi, Michele Dibattista, Anna Menini. Pflugers Arch 2009
14
The Sixth Transmembrane Segment Is a Major Gating Component of the TMEM16A Calcium-Activated Chloride Channel.
Christian J Peters, John M Gilchrist, Jason Tien, Neville P Bethel, Lijun Qi, Tingxu Chen, Lynn Wang, Yuh Nung Jan, Michael Grabe, Lily Y Jan. Neuron 2018
Christian J Peters, John M Gilchrist, Jason Tien, Neville P Bethel, Lijun Qi, Tingxu Chen, Lynn Wang, Yuh Nung Jan, Michael Grabe, Lily Y Jan. Neuron 2018
29
A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity.
Jason Tien, Christian J Peters, Xiu Ming Wong, Tong Cheng, Yuh Nung Jan, Lily Yeh Jan, Huanghe Yang. Elife 2014
Jason Tien, Christian J Peters, Xiu Ming Wong, Tong Cheng, Yuh Nung Jan, Lily Yeh Jan, Huanghe Yang. Elife 2014
14
Contrasting effects of phosphatidylinositol 4,5-bisphosphate on cloned TMEM16A and TMEM16B channels.
Chau M Ta, Kathryn E Acheson, Nils J G Rorsman, Remco C Jongkind, Paolo Tammaro. Br J Pharmacol 2017
Chau M Ta, Kathryn E Acheson, Nils J G Rorsman, Remco C Jongkind, Paolo Tammaro. Br J Pharmacol 2017
43
Identification of a lipid scrambling domain in ANO6/TMEM16F.
Kuai Yu, Jarred M Whitlock, Kyleen Lee, Eric A Ortlund, Yuan Yuan Cui, H Criss Hartzell. Elife 2015
Kuai Yu, Jarred M Whitlock, Kyleen Lee, Eric A Ortlund, Yuan Yuan Cui, H Criss Hartzell. Elife 2015
13
Inhibition of Ca(2+)-activated Cl(-) channel ANO1/TMEM16A expression suppresses tumor growth and invasiveness in human prostate carcinoma.
Wen Liu, Min Lu, Baogang Liu, Yi Huang, KeWei Wang. Cancer Lett 2012
Wen Liu, Min Lu, Baogang Liu, Yi Huang, KeWei Wang. Cancer Lett 2012
13
ANO1/TMEM16A interacts with EGFR and correlates with sensitivity to EGFR-targeting therapy in head and neck cancer.
Anke Bill, Abraham Gutierrez, Sucheta Kulkarni, Carolyn Kemp, Debora Bonenfant, Hans Voshol, Umamaheswar Duvvuri, L Alex Gaither. Oncotarget 2015
Anke Bill, Abraham Gutierrez, Sucheta Kulkarni, Carolyn Kemp, Debora Bonenfant, Hans Voshol, Umamaheswar Duvvuri, L Alex Gaither. Oncotarget 2015
21
International Union of Basic and Clinical Pharmacology. LXXXV: calcium-activated chloride channels.
Fen Huang, Xiuming Wong, Lily Y Jan. Pharmacol Rev 2012
Fen Huang, Xiuming Wong, Lily Y Jan. Pharmacol Rev 2012
13
MicroRNA-381 inhibits the metastasis of gastric cancer by targeting TMEM16A expression.
Qinghua Cao, Fang Liu, Kaiyuan Ji, Ni Liu, Yuan He, Wenhui Zhang, Liantang Wang. J Exp Clin Cancer Res 2017
Qinghua Cao, Fang Liu, Kaiyuan Ji, Ni Liu, Yuan He, Wenhui Zhang, Liantang Wang. J Exp Clin Cancer Res 2017
13
Inhibition of Calcium-Activated Chloride Channel ANO1/TMEM16A Suppresses Tumor Growth and Invasion in Human Lung Cancer.
Linghan Jia, Wen Liu, Lizhao Guan, Min Lu, KeWei Wang. PLoS One 2015
Linghan Jia, Wen Liu, Lizhao Guan, Min Lu, KeWei Wang. PLoS One 2015
17
Independent activation of ion conduction pores in the double-barreled calcium-activated chloride channel TMEM16A.
Novandy K Lim, Andy K M Lam, Raimund Dutzler. J Gen Physiol 2016
Novandy K Lim, Andy K M Lam, Raimund Dutzler. J Gen Physiol 2016
24
Independent activation of distinct pores in dimeric TMEM16A channels.
Grace Jeng, Muskaan Aggarwal, Wei-Ping Yu, Tsung-Yu Chen. J Gen Physiol 2016
Grace Jeng, Muskaan Aggarwal, Wei-Ping Yu, Tsung-Yu Chen. J Gen Physiol 2016
27
Regulation of TMEM16A chloride channel properties by alternative splicing.
Loretta Ferrera, Antonella Caputo, Ifeoma Ubby, Erica Bussani, Olga Zegarra-Moran, Roberto Ravazzolo, Franco Pagani, Luis J V Galietta. J Biol Chem 2009
Loretta Ferrera, Antonella Caputo, Ifeoma Ubby, Erica Bussani, Olga Zegarra-Moran, Roberto Ravazzolo, Franco Pagani, Luis J V Galietta. J Biol Chem 2009
13
ANO2 is the cilial calcium-activated chloride channel that may mediate olfactory amplification.
Aaron B Stephan, Eleen Y Shum, Sarah Hirsh, Katherine D Cygnar, Johannes Reisert, Haiqing Zhao. Proc Natl Acad Sci U S A 2009
Aaron B Stephan, Eleen Y Shum, Sarah Hirsh, Katherine D Cygnar, Johannes Reisert, Haiqing Zhao. Proc Natl Acad Sci U S A 2009
13
Phosphatidylinositol 4,5-bisphosphate (PIP2) and Ca2+ are both required to open the Cl- channel TMEM16A.
Maiwase Tembo, Katherine L Wozniak, Rachel E Bainbridge, Anne E Carlson. J Biol Chem 2019
Maiwase Tembo, Katherine L Wozniak, Rachel E Bainbridge, Anne E Carlson. J Biol Chem 2019
54
A network of phosphatidylinositol 4,5-bisphosphate binding sites regulates gating of the Ca2+-activated Cl- channel ANO1 (TMEM16A).
Kuai Yu, Tao Jiang, YuanYuan Cui, Emad Tajkhorshid, H Criss Hartzell. Proc Natl Acad Sci U S A 2019
Kuai Yu, Tao Jiang, YuanYuan Cui, Emad Tajkhorshid, H Criss Hartzell. Proc Natl Acad Sci U S A 2019
46
Explaining calcium-dependent gating of anoctamin-1 chloride channels requires a revised topology.
Kuai Yu, Charity Duran, Zhiqiang Qu, Yuan-Yuan Cui, H Criss Hartzell. Circ Res 2012
Kuai Yu, Charity Duran, Zhiqiang Qu, Yuan-Yuan Cui, H Criss Hartzell. Circ Res 2012
12
ANO1 amplification and expression in HNSCC with a high propensity for future distant metastasis and its functions in HNSCC cell lines.
C Ayoub, C Wasylyk, Y Li, E Thomas, L Marisa, A Robé, M Roux, J Abecassis, A de Reyniès, B Wasylyk. Br J Cancer 2010
C Ayoub, C Wasylyk, Y Li, E Thomas, L Marisa, A Robé, M Roux, J Abecassis, A de Reyniès, B Wasylyk. Br J Cancer 2010
12
Enhanced expression of ANO1 in head and neck squamous cell carcinoma causes cell migration and correlates with poor prognosis.
Christian Ruiz, Joana Raquel Martins, Florian Rudin, Sandra Schneider, Tanja Dietsche, Claude A Fischer, Luigi Tornillo, Luigi M Terracciano, Rainer Schreiber, Lukas Bubendorf,[...]. PLoS One 2012
Christian Ruiz, Joana Raquel Martins, Florian Rudin, Sandra Schneider, Tanja Dietsche, Claude A Fischer, Luigi Tornillo, Luigi M Terracciano, Rainer Schreiber, Lukas Bubendorf,[...]. PLoS One 2012
12
Calcium-dependent phospholipid scramblase activity of TMEM16 protein family members.
Jun Suzuki, Toshihiro Fujii, Takeshi Imao, Kenji Ishihara, Hiroshi Kuba, Shigekazu Nagata. J Biol Chem 2013
Jun Suzuki, Toshihiro Fujii, Takeshi Imao, Kenji Ishihara, Hiroshi Kuba, Shigekazu Nagata. J Biol Chem 2013
12
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.