C W Greider. Mol Cell Biol 1991
Times Cited: 194
Times Cited: 194
Times Cited
Times Co-cited
Similarity
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts.
C W Greider, E H Blackburn. Cell 1985
C W Greider, E H Blackburn. Cell 1985
43
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis.
C W Greider, E H Blackburn. Nature 1989
C W Greider, E H Blackburn. Nature 1989
42
Specific association of human telomerase activity with immortal cells and cancer.
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
40
Reverse transcriptase motifs in the catalytic subunit of telomerase.
J Lingner, T R Hughes, A Shevchenko, M Mann, V Lundblad, T R Cech. Science 1997
J Lingner, T R Hughes, A Shevchenko, M Mann, V Lundblad, T R Cech. Science 1997
39
Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase.
Steven A Jacobs, Elaine R Podell, Thomas R Cech. Nat Struct Mol Biol 2006
Steven A Jacobs, Elaine R Podell, Thomas R Cech. Nat Struct Mol Biol 2006
35
The POT1-TPP1 telomere complex is a telomerase processivity factor.
Feng Wang, Elaine R Podell, Arthur J Zaug, Yuting Yang, Paul Baciu, Thomas R Cech, Ming Lei. Nature 2007
Feng Wang, Elaine R Podell, Arthur J Zaug, Yuting Yang, Paul Baciu, Thomas R Cech, Ming Lei. Nature 2007
32
The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats.
G B Morin. Cell 1989
G B Morin. Cell 1989
27
Structure of the Tribolium castaneum telomerase catalytic subunit TERT.
Andrew J Gillis, Anthony P Schuller, Emmanuel Skordalakes. Nature 2008
Andrew J Gillis, Anthony P Schuller, Emmanuel Skordalakes. Nature 2008
26
Telomerase catalytic subunit homologs from fission yeast and human.
T M Nakamura, G B Morin, K B Chapman, S L Weinrich, W H Andrews, J Lingner, C B Harley, T R Cech. Science 1997
T M Nakamura, G B Morin, K B Chapman, S L Weinrich, W H Andrews, J Lingner, C B Harley, T R Cech. Science 1997
25
Adding to the ends: what makes telomerase processive and how important is it?
Neal F Lue. Bioessays 2004
Neal F Lue. Bioessays 2004
42
A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon.
A M Olovnikov. J Theor Biol 1973
A M Olovnikov. J Theor Biol 1973
24
The structure and function of telomerase reverse transcriptase.
Chantal Autexier, Neal F Lue. Annu Rev Biochem 2006
Chantal Autexier, Neal F Lue. Annu Rev Biochem 2006
24
The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity.
C W Greider, E H Blackburn. Cell 1987
C W Greider, E H Blackburn. Cell 1987
23
RNA binding domain of telomerase reverse transcriptase.
C K Lai, J R Mitchell, K Collins. Mol Cell Biol 2001
C K Lai, J R Mitchell, K Collins. Mol Cell Biol 2001
22
Template boundary definition in Tetrahymena telomerase.
Cary K Lai, Michael C Miller, Kathleen Collins. Genes Dev 2002
Cary K Lai, Michael C Miller, Kathleen Collins. Genes Dev 2002
26
Functional organization of repeat addition processivity and DNA synthesis determinants in the human telomerase multimer.
Tara J Moriarty, Delphine T Marie-Egyptienne, Chantal Autexier. Mol Cell Biol 2004
Tara J Moriarty, Delphine T Marie-Egyptienne, Chantal Autexier. Mol Cell Biol 2004
23
TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase.
Huawei Xin, Dan Liu, Ma Wan, Amin Safari, Hyeung Kim, Wen Sun, Matthew S O'Connor, Zhou Songyang. Nature 2007
Huawei Xin, Dan Liu, Ma Wan, Amin Safari, Hyeung Kim, Wen Sun, Matthew S O'Connor, Zhou Songyang. Nature 2007
21
Telomeres shorten during ageing of human fibroblasts.
C B Harley, A B Futcher, C W Greider. Nature 1990
C B Harley, A B Futcher, C W Greider. Nature 1990
20
Shelterin: the protein complex that shapes and safeguards human telomeres.
Titia de Lange. Genes Dev 2005
Titia de Lange. Genes Dev 2005
20
POT1-TPP1 enhances telomerase processivity by slowing primer dissociation and aiding translocation.
Chrysa M Latrick, Thomas R Cech. EMBO J 2010
Chrysa M Latrick, Thomas R Cech. EMBO J 2010
20
The anchor site of telomerase from Euplotes aediculatus revealed by photo-cross-linking to single- and double-stranded DNA primers.
P W Hammond, T N Lively, T R Cech. Mol Cell Biol 1997
P W Hammond, T N Lively, T R Cech. Mol Cell Biol 1997
21
37
Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT.
S L Weinrich, R Pruzan, L Ma, M Ouellette, V M Tesmer, S E Holt, A G Bodnar, S Lichtsteiner, N W Kim, J B Trager,[...]. Nat Genet 1997
S L Weinrich, R Pruzan, L Ma, M Ouellette, V M Tesmer, S E Holt, A G Bodnar, S Lichtsteiner, N W Kim, J B Trager,[...]. Nat Genet 1997
19
The RNA component of human telomerase.
J Feng, W D Funk, S S Wang, S L Weinrich, A A Avilion, C P Chiu, R R Adams, E Chang, R C Allsopp, J Yu. Science 1995
J Feng, W D Funk, S S Wang, S L Weinrich, A A Avilion, C P Chiu, R R Adams, E Chang, R C Allsopp, J Yu. Science 1995
19
Characterization of physical and functional anchor site interactions in human telomerase.
Haley D M Wyatt, Deirdre A Lobb, Tara L Beattie. Mol Cell Biol 2007
Haley D M Wyatt, Deirdre A Lobb, Tara L Beattie. Mol Cell Biol 2007
38
19
Structural basis for telomerase catalytic subunit TERT binding to RNA template and telomeric DNA.
Meghan Mitchell, Andrew Gillis, Mizuko Futahashi, Haruhiko Fujiwara, Emmanuel Skordalakes. Nat Struct Mol Biol 2010
Meghan Mitchell, Andrew Gillis, Mizuko Futahashi, Haruhiko Fujiwara, Emmanuel Skordalakes. Nat Struct Mol Biol 2010
19
Determinants in mammalian telomerase RNA that mediate enzyme processivity and cross-species incompatibility.
Jiunn-Liang Chen, Carol W Greider. EMBO J 2003
Jiunn-Liang Chen, Carol W Greider. EMBO J 2003
18
The C terminus of the human telomerase reverse transcriptase is a determinant of enzyme processivity.
Sylvain Huard, Tara J Moriarty, Chantal Autexier. Nucleic Acids Res 2003
Sylvain Huard, Tara J Moriarty, Chantal Autexier. Nucleic Acids Res 2003
25
18
High-resolution physical and functional mapping of the template adjacent DNA binding site in catalytically active telomerase.
Erez Romi, Nava Baran, Marina Gantman, Michael Shmoish, Bosun Min, Kathleen Collins, Haim Manor. Proc Natl Acad Sci U S A 2007
Erez Romi, Nava Baran, Marina Gantman, Michael Shmoish, Bosun Min, Kathleen Collins, Haim Manor. Proc Natl Acad Sci U S A 2007
56
RNA/DNA hybrid binding affinity determines telomerase template-translocation efficiency.
Xiaodong Qi, Mingyi Xie, Andrew F Brown, Christopher J Bley, Joshua D Podlevsky, Julian J-L Chen. EMBO J 2012
Xiaodong Qi, Mingyi Xie, Andrew F Brown, Christopher J Bley, Joshua D Podlevsky, Julian J-L Chen. EMBO J 2012
40
A conserved telomerase motif within the catalytic domain of telomerase reverse transcriptase is specifically required for repeat addition processivity.
Neal F Lue, You-Chin Lin, I Saira Mian. Mol Cell Biol 2003
Neal F Lue, You-Chin Lin, I Saira Mian. Mol Cell Biol 2003
33
Telomere length homeostasis is achieved via a switch between telomerase- extendible and -nonextendible states.
M Teresa Teixeira, Milica Arneric, Peter Sperisen, Joachim Lingner. Cell 2004
M Teresa Teixeira, Milica Arneric, Peter Sperisen, Joachim Lingner. Cell 2004
17
An anchor site-type defect in human telomerase that disrupts telomere length maintenance and cellular immortalization.
Tara J Moriarty, Ryan J Ward, Michael A S Taboski, Chantal Autexier. Mol Biol Cell 2005
Tara J Moriarty, Ryan J Ward, Michael A S Taboski, Chantal Autexier. Mol Biol Cell 2005
38
17
Telomerase recognizes its template by using an adjacent RNA motif.
Michael C Miller, Kathleen Collins. Proc Natl Acad Sci U S A 2002
Michael C Miller, Kathleen Collins. Proc Natl Acad Sci U S A 2002
27
Template boundary definition in mammalian telomerase.
Jiunn-Liang Chen, Carol W Greider. Genes Dev 2003
Jiunn-Liang Chen, Carol W Greider. Genes Dev 2003
17
Requirements for the dGTP-dependent repeat addition processivity of recombinant Tetrahymena telomerase.
C D Hardy, C S Schultz, K Collins. J Biol Chem 2001
C D Hardy, C S Schultz, K Collins. J Biol Chem 2001
35
Multiple DNA-binding sites in Tetrahymena telomerase.
Sharon N Finger, Tracy M Bryan. Nucleic Acids Res 2008
Sharon N Finger, Tracy M Bryan. Nucleic Acids Res 2008
56
Mutation in TERT separates processivity from anchor-site function.
Arthur J Zaug, Elaine R Podell, Thomas R Cech. Nat Struct Mol Biol 2008
Arthur J Zaug, Elaine R Podell, Thomas R Cech. Nat Struct Mol Biol 2008
36
Mammalian telomeres end in a large duplex loop.
J D Griffith, L Comeau, S Rosenfield, R M Stansel, A Bianchi, H Moss, T de Lange. Cell 1999
J D Griffith, L Comeau, S Rosenfield, R M Stansel, A Bianchi, H Moss, T de Lange. Cell 1999
16
Tetrahymena telomerase catalyzes nucleolytic cleavage and nonprocessive elongation.
K Collins, C W Greider. Genes Dev 1993
K Collins, C W Greider. Genes Dev 1993
16
Telomere length homeostasis requires that telomerase levels are limiting.
Gaël Cristofari, Joachim Lingner. EMBO J 2006
Gaël Cristofari, Joachim Lingner. EMBO J 2006
16
A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis.
Andrew S Venteicher, Eladio B Abreu, Zhaojing Meng, Kelly E McCann, Rebecca M Terns, Timothy D Veenstra, Michael P Terns, Steven E Artandi. Science 2009
Andrew S Venteicher, Eladio B Abreu, Zhaojing Meng, Kelly E McCann, Rebecca M Terns, Timothy D Veenstra, Michael P Terns, Steven E Artandi. Science 2009
16
Human telomerase domain interactions capture DNA for TEN domain-dependent processive elongation.
Aaron R Robart, Kathleen Collins. Mol Cell 2011
Aaron R Robart, Kathleen Collins. Mol Cell 2011
31
A mutant of Tetrahymena telomerase reverse transcriptase with increased processivity.
T M Bryan, K J Goodrich, T R Cech. J Biol Chem 2000
T M Bryan, K J Goodrich, T R Cech. J Biol Chem 2000
20
Pot1, the putative telomere end-binding protein in fission yeast and humans.
P Baumann, T R Cech. Science 2001
P Baumann, T R Cech. Science 2001
15
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.