A citation-based method for searching scientific literature

Judit Pallos, Laszlo Bodai, Tamas Lukacsovich, Judith M Purcell, Joan S Steffan, Leslie Michels Thompson, J Lawrence Marsh. Hum Mol Genet 2008
Times Cited: 207







List of co-cited articles
1827 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease.
Tiago Fleming Outeiro, Eirene Kontopoulos, Stephen M Altmann, Irina Kufareva, Katherine E Strathearn, Allison M Amore, Catherine B Volk, Michele M Maxwell, Jean-Christophe Rochet, Pamela J McLean,[...]. Science 2007
783
32

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila.
J S Steffan, L Bodai, J Pallos, M Poelman, A McCampbell, B L Apostol, A Kazantsev, E Schmidt, Y Z Zhu, M Greenwald,[...]. Nature 2001
912
31

SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis.
Ruth Luthi-Carter, David M Taylor, Judit Pallos, Emmanuel Lambert, Allison Amore, Alex Parker, Hilary Moffitt, Donna L Smith, Heike Runne, Ozgun Gokce,[...]. Proc Natl Acad Sci U S A 2010
236
30

The sirtuin 2 inhibitor AK-7 is neuroprotective in Huntington's disease mouse models.
Vanita Chopra, Luisa Quinti, Jinho Kim, Lorraine Vollor, K Lakshmi Narayanan, Christina Edgerly, Patricia M Cipicchio, Molly A Lauver, Soo Hyuk Choi, Richard B Silverman,[...]. Cell Rep 2012
124
24

Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets.
Mali Jiang, Jiawei Wang, Jinrong Fu, Lin Du, Hyunkyung Jeong, Tim West, Lan Xiang, Qi Peng, Zhipeng Hou, Huan Cai,[...]. Nat Med 2011
247
24

Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway.
Hyunkyung Jeong, Dena E Cohen, Libin Cui, Andrea Supinski, Jeffrey N Savas, Joseph R Mazzulli, John R Yates, Laura Bordone, Leonard Guarente, Dimitri Krainc. Nat Med 2011
251
24


A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease.
Marianne R Smith, Adeela Syed, Tamas Lukacsovich, Judy Purcell, Brett A Barbaro, Shane A Worthge, Stephen R Wei, Giuseppe Pollio, Letizia Magnoni, Carla Scali,[...]. Hum Mol Genet 2014
87
24

The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice.
Elizabeth A Thomas, Giovanni Coppola, Paula A Desplats, Bin Tang, Elisabetta Soragni, Ryan Burnett, Fuying Gao, Kelsey M Fitzgerald, Jenna F Borok, David Herman,[...]. Proc Natl Acad Sci U S A 2008
214
20

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity.
F C Nucifora , M Sasaki, M F Peters, H Huang, J K Cooper, M Yamada, H Takahashi, S Tsuji, J Troncoso, V L Dawson,[...]. Science 2001
823
20

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease.
Emma Hockly, Victoria M Richon, Benjamin Woodman, Donna L Smith, Xianbo Zhou, Eddie Rosa, Kirupa Sathasivam, Shabnam Ghazi-Noori, Amarbirpal Mahal, Philip A S Lowden,[...]. Proc Natl Acad Sci U S A 2003
635
19

An exploratory double-blind, randomized clinical trial with selisistat, a SirT1 inhibitor, in patients with Huntington's disease.
Sigurd D Süssmuth, Salman Haider, G Bernhard Landwehrmeyer, Ruth Farmer, Chris Frost, Giovanna Tripepi, Claus A Andersen, Marco Di Bacco, Claudia Lamanna, Enrica Diodato,[...]. Br J Clin Pharmacol 2015
93
20

SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis.
Dohoon Kim, Minh Dang Nguyen, Matthew M Dobbin, Andre Fischer, Farahnaz Sananbenesi, Joseph T Rodgers, Ivana Delalle, Joseph A Baur, Guangchao Sui, Sean M Armour,[...]. EMBO J 2007
791
18

Histone deacetylase inhibition by sodium butyrate chemotherapy ameliorates the neurodegenerative phenotype in Huntington's disease mice.
Robert J Ferrante, James K Kubilus, Junghee Lee, Hoon Ryu, Ayshe Beesen, Birgit Zucker, Karen Smith, Neil W Kowall, Rajiv R Ratan, Ruth Luthi-Carter,[...]. J Neurosci 2003
492
18

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.
J S Steffan, A Kazantsev, O Spasic-Boskovic, M Greenwald, Y Z Zhu, H Gohler, E E Wanker, G P Bates, D E Housman, L M Thompson. Proc Natl Acad Sci U S A 2000
795
17


Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons.
J Alex Parker, Margarita Arango, Salima Abderrahmane, Emmanuel Lambert, Cendrine Tourette, Hélène Catoire, Christian Néri. Nat Genet 2005
381
16

Acetylation targets mutant huntingtin to autophagosomes for degradation.
Hyunkyung Jeong, Florian Then, Thomas J Melia, Joseph R Mazzulli, Libin Cui, Jeffrey N Savas, Cindy Voisine, Paolo Paganetti, Naoko Tanese, Anne C Hart,[...]. Cell 2009
279
16

Differential contributions of Caenorhabditis elegans histone deacetylases to huntingtin polyglutamine toxicity.
Emily A Bates, Martin Victor, Adriana K Jones, Yang Shi, Anne C Hart. J Neurosci 2006
116
15

Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease.
Gabriella Gardian, Susan E Browne, Dong-Kug Choi, Peter Klivenyi, Jason Gregorio, James K Kubilus, Hoon Ryu, Brett Langley, Rajiv R Ratan, Robert J Ferrante,[...]. J Biol Chem 2005
338
15

Mammalian sirtuins: biological insights and disease relevance.
Marcia C Haigis, David A Sinclair. Annu Rev Pathol 2010
15


The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase.
Brian J North, Brett L Marshall, Margie T Borra, John M Denu, Eric Verdin. Mol Cell 2003
14

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan.
Konrad T Howitz, Kevin J Bitterman, Haim Y Cohen, Dudley W Lamming, Siva Lavu, Jason G Wood, Robert E Zipkin, Phuong Chung, Anne Kisielewski, Li-Li Zhang,[...]. Nature 2003
14

Histones associated with downregulated genes are hypo-acetylated in Huntington's disease models.
Ghazaleh Sadri-Vakili, Bérengère Bouzou, Caroline L Benn, Mee-Ohk Kim, Prianka Chawla, Ryan P Overland, Kelly E Glajch, Eva Xia, Zhihua Qiu, Steven M Hersch,[...]. Hum Mol Genet 2007
158
13

Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease.
Haiqun Jia, Judit Pallos, Vincent Jacques, Alice Lau, Bin Tang, Andrew Cooper, Adeela Syed, Judith Purcell, Yi Chen, Shefali Sharma,[...]. Neurobiol Dis 2012
117
13




Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase.
Haim Y Cohen, Christine Miller, Kevin J Bitterman, Nathan R Wall, Brian Hekking, Benedikt Kessler, Konrad T Howitz, Myriam Gorospe, Rafael de Cabo, David A Sinclair. Science 2004
12

Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation.
Jim P Dompierre, Juliette D Godin, Bénédicte C Charrin, Fabrice P Cordelières, Stephen J King, Sandrine Humbert, Frédéric Saudou. J Neurosci 2007
563
12

Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau.
Kim N Green, Joan S Steffan, Hilda Martinez-Coria, Xuemin Sun, Steven S Schreiber, Leslie Michels Thompson, Frank M LaFerla. J Neurosci 2008
252
12

Resveratrol protects against peripheral deficits in a mouse model of Huntington's disease.
Daniel J Ho, Noel Y Calingasan, Elizabeth Wille, Magali Dumont, M Flint Beal. Exp Neurol 2010
97
12

Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.
Libin Cui, Hyunkyung Jeong, Fran Borovecki, Christopher N Parkhurst, Naoko Tanese, Dimitri Krainc. Cell 2006
763
12

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha.
Marie Lagouge, Carmen Argmann, Zachary Gerhart-Hines, Hamid Meziane, Carles Lerin, Frederic Daussin, Nadia Messadeq, Jill Milne, Philip Lambert, Peter Elliott,[...]. Cell 2006
12

Nucleocytoplasmic shuttling of the NAD+-dependent histone deacetylase SIRT1.
Masaya Tanno, Jun Sakamoto, Tetsuji Miura, Kazuaki Shimamoto, Yoshiyuki Horio. J Biol Chem 2007
537
11

SAHA decreases HDAC 2 and 4 levels in vivo and improves molecular phenotypes in the R6/2 mouse model of Huntington's disease.
Michal Mielcarek, Caroline L Benn, Sophie A Franklin, Donna L Smith, Ben Woodman, Paul A Marks, Gillian P Bates. PLoS One 2011
116
11

ESET/SETDB1 gene expression and histone H3 (K9) trimethylation in Huntington's disease.
Hoon Ryu, Junghee Lee, Sean W Hagerty, Byoung Yul Soh, Sara E McAlpin, Kerry A Cormier, Karen M Smith, Robert J Ferrante. Proc Natl Acad Sci U S A 2006
217
11

Genome-wide histone acetylation is altered in a transgenic mouse model of Huntington's disease.
Karen N McFarland, Sudeshna Das, Ting Ting Sun, Dmitri Leyfer, Eva Xia, Gavin R Sangrey, Alexandre Kuhn, Ruth Luthi-Carter, Timothy W Clark, Ghazaleh Sadri-Vakili,[...]. PLoS One 2012
59
18

Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1.
Andrew D Napper, Jeffrey Hixon, Thomas McDonagh, Kenneth Keavey, Jean-Francois Pons, Jonathan Barker, Wei Tsung Yau, Patricia Amouzegh, Adam Flegg, Estelle Hamelin,[...]. J Med Chem 2005
359
11

Evidence for a common mechanism of SIRT1 regulation by allosteric activators.
Basil P Hubbard, Ana P Gomes, Han Dai, Jun Li, April W Case, Thomas Considine, Thomas V Riera, Jessica E Lee, Sook Yen E, Dudley W Lamming,[...]. Science 2013
428
11

Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins.
Eriko Michishita, Jean Y Park, Jenna M Burneskis, J Carl Barrett, Izumi Horikawa. Mol Biol Cell 2005
970
10

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1.
Joseph T Rodgers, Carlos Lerin, Wilhelm Haas, Steven P Gygi, Bruce M Spiegelman, Pere Puigserver. Nature 2005
10


Sir2 mediates longevity in the fly through a pathway related to calorie restriction.
Blanka Rogina, Stephen L Helfand. Proc Natl Acad Sci U S A 2004
941
10

SIRT2 regulates NF-κB dependent gene expression through deacetylation of p65 Lys310.
Karin M Rothgiesser, Süheda Erener, Susanne Waibel, Bernhard Lüscher, Michael O Hottiger. J Cell Sci 2010
260
10

Regional and cellular gene expression changes in human Huntington's disease brain.
Angela Hodges, Andrew D Strand, Aaron K Aragaki, Alexandre Kuhn, Thierry Sengstag, Gareth Hughes, Lyn A Elliston, Cathy Hartog, Darlene R Goldstein, Doris Thu,[...]. Hum Mol Genet 2006
540
10

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
10

SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1.
Michelle Pacholec, John E Bleasdale, Boris Chrunyk, David Cunningham, Declan Flynn, Robert S Garofalo, David Griffith, Matt Griffor, Pat Loulakis, Brandon Pabst,[...]. J Biol Chem 2010
682
10

The Sirtuin 2 microtubule deacetylase is an abundant neuronal protein that accumulates in the aging CNS.
Michele M Maxwell, Elizabeth M Tomkinson, Johnathan Nobles, John W Wizeman, Allison M Amore, Luisa Quinti, Vanita Chopra, Steven M Hersch, Aleksey G Kazantsev. Hum Mol Genet 2011
132
10


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.