Laura D Bauler, Colin S Duckett, Mary X D O'Riordan. PLoS Pathog 2008
Times Cited: 81
Times Cited: 81
Times Cited
Times Co-cited
Similarity
XIAP mediates NOD signaling via interaction with RIP2.
Andreas Krieg, Ricardo G Correa, Jason B Garrison, Gaëlle Le Negrate, Kate Welsh, Ziwei Huang, Wolfram T Knoefel, John C Reed. Proc Natl Acad Sci U S A 2009
Andreas Krieg, Ricardo G Correa, Jason B Garrison, Gaëlle Le Negrate, Kate Welsh, Ziwei Huang, Wolfram T Knoefel, John C Reed. Proc Natl Acad Sci U S A 2009
54
XIAP deficiency in humans causes an X-linked lymphoproliferative syndrome.
Stéphanie Rigaud, Marie-Claude Fondanèche, Nathalie Lambert, Benoit Pasquier, Véronique Mateo, Pauline Soulas, Lionel Galicier, Françoise Le Deist, Frédéric Rieux-Laucat, Patrick Revy,[...]. Nature 2006
Stéphanie Rigaud, Marie-Claude Fondanèche, Nathalie Lambert, Benoit Pasquier, Véronique Mateo, Pauline Soulas, Lionel Galicier, Françoise Le Deist, Frédéric Rieux-Laucat, Patrick Revy,[...]. Nature 2006
49
The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity.
Rune Busk Damgaard, Ueli Nachbur, Monica Yabal, Wendy Wei-Lynn Wong, Berthe Katrine Fiil, Mischa Kastirr, Eva Rieser, James Arthur Rickard, Aleksandra Bankovacki, Christian Peschel,[...]. Mol Cell 2012
Rune Busk Damgaard, Ueli Nachbur, Monica Yabal, Wendy Wei-Lynn Wong, Berthe Katrine Fiil, Mischa Kastirr, Eva Rieser, James Arthur Rickard, Aleksandra Bankovacki, Christian Peschel,[...]. Mol Cell 2012
48
Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2.
Mathieu J M Bertrand, Karine Doiron, Katherine Labbé, Robert G Korneluk, Philip A Barker, Maya Saleh. Immunity 2009
Mathieu J M Bertrand, Karine Doiron, Katherine Labbé, Robert G Korneluk, Philip A Barker, Maya Saleh. Immunity 2009
43
cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination.
Mathieu J M Bertrand, Snezana Milutinovic, Kathleen M Dickson, Wai Chi Ho, Alain Boudreault, Jon Durkin, John W Gillard, James B Jaquith, Stephen J Morris, Philip A Barker. Mol Cell 2008
Mathieu J M Bertrand, Snezana Milutinovic, Kathleen M Dickson, Wai Chi Ho, Alain Boudreault, Jon Durkin, John W Gillard, James B Jaquith, Stephen J Morris, Philip A Barker. Mol Cell 2008
37
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis.
James E Vince, W Wei-Lynn Wong, Nufail Khan, Rebecca Feltham, Diep Chau, Afsar U Ahmed, Christopher A Benetatos, Srinivas K Chunduru, Stephen M Condon, Mark McKinlay,[...]. Cell 2007
James E Vince, W Wei-Lynn Wong, Nufail Khan, Rebecca Feltham, Diep Chau, Afsar U Ahmed, Christopher A Benetatos, Srinivas K Chunduru, Stephen M Condon, Mark McKinlay,[...]. Cell 2007
35
Deficiency of XIAP leads to sensitization for Chlamydophila pneumoniae pulmonary infection and dysregulation of innate immune response in mice.
Hridayesh Prakash, Marco Albrecht, Daniel Becker, Tanja Kuhlmann, Thomas Rudel. J Biol Chem 2010
Hridayesh Prakash, Marco Albrecht, Daniel Becker, Tanja Kuhlmann, Thomas Rudel. J Biol Chem 2010
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Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling.
Rune Busk Damgaard, Berthe Katrine Fiil, Carsten Speckmann, Monica Yabal, Udo zur Stadt, Simon Bekker-Jensen, Philipp J Jost, Stephan Ehl, Niels Mailand, Mads Gyrd-Hansen. EMBO Mol Med 2013
Rune Busk Damgaard, Berthe Katrine Fiil, Carsten Speckmann, Monica Yabal, Udo zur Stadt, Simon Bekker-Jensen, Philipp J Jost, Stephan Ehl, Niels Mailand, Mads Gyrd-Hansen. EMBO Mol Med 2013
30
IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis.
Eugene Varfolomeev, John W Blankenship, Sarah M Wayson, Anna V Fedorova, Nobuhiko Kayagaki, Parie Garg, Kerry Zobel, Jasmin N Dynek, Linda O Elliott, Heidi J A Wallweber,[...]. Cell 2007
Eugene Varfolomeev, John W Blankenship, Sarah M Wayson, Anna V Fedorova, Nobuhiko Kayagaki, Parie Garg, Kerry Zobel, Jasmin N Dynek, Linda O Elliott, Heidi J A Wallweber,[...]. Cell 2007
29
Characterization of XIAP-deficient mice.
H Harlin, S B Reffey, C S Duckett, T Lindsten, C B Thompson. Mol Cell Biol 2001
H Harlin, S B Reffey, C S Duckett, T Lindsten, C B Thompson. Mol Cell Biol 2001
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A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation.
Mizuho Hasegawa, Yukari Fujimoto, Peter C Lucas, Hiroyasu Nakano, Koichi Fukase, Gabriel Núñez, Naohiro Inohara. EMBO J 2008
Mizuho Hasegawa, Yukari Fujimoto, Peter C Lucas, Hiroyasu Nakano, Koichi Fukase, Gabriel Núñez, Naohiro Inohara. EMBO J 2008
27
XIAP deficiency: a unique primary immunodeficiency best classified as X-linked familial hemophagocytic lymphohistiocytosis and not as X-linked lymphoproliferative disease.
Rebecca A Marsh, Lisa Madden, Brenda J Kitchen, Rajen Mody, Brad McClimon, Michael B Jordan, Jack J Bleesing, Kejian Zhang, Alexandra H Filipovich. Blood 2010
Rebecca A Marsh, Lisa Madden, Brenda J Kitchen, Rajen Mody, Brad McClimon, Michael B Jordan, Jack J Bleesing, Kejian Zhang, Alexandra H Filipovich. Blood 2010
25
Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.
James E Vince, W Wei-Lynn Wong, Ian Gentle, Kate E Lawlor, Ramanjaneyulu Allam, Lorraine O'Reilly, Kylie Mason, Olaf Gross, Stephen Ma, Greta Guarda,[...]. Immunity 2012
James E Vince, W Wei-Lynn Wong, Ian Gentle, Kate E Lawlor, Ramanjaneyulu Allam, Lorraine O'Reilly, Kylie Mason, Olaf Gross, Stephen Ma, Greta Guarda,[...]. Immunity 2012
25
XIAP induces NF-kappaB activation via the BIR1/TAB1 interaction and BIR1 dimerization.
Miao Lu, Su-Chang Lin, Yihua Huang, Young Jun Kang, Rebecca Rich, Yu-Chih Lo, David Myszka, Jiahuai Han, Hao Wu. Mol Cell 2007
Miao Lu, Su-Chang Lin, Yihua Huang, Young Jun Kang, Rebecca Rich, Yu-Chih Lo, David Myszka, Jiahuai Han, Hao Wu. Mol Cell 2007
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Inhibitor of apoptosis protein cIAP2 is essential for lipopolysaccharide-induced macrophage survival.
Damiano Conte, Martin Holcik, Charles A Lefebvre, Eric Lacasse, David J Picketts, Kathryn E Wright, Robert G Korneluk. Mol Cell Biol 2006
Damiano Conte, Martin Holcik, Charles A Lefebvre, Eric Lacasse, David J Picketts, Kathryn E Wright, Robert G Korneluk. Mol Cell Biol 2006
23
Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation.
D J Mahoney, H H Cheung, R Lejmi Mrad, S Plenchette, C Simard, E Enwere, V Arora, T W Mak, E C Lacasse, J Waring,[...]. Proc Natl Acad Sci U S A 2008
D J Mahoney, H H Cheung, R Lejmi Mrad, S Plenchette, C Simard, E Enwere, V Arora, T W Mak, E C Lacasse, J Waring,[...]. Proc Natl Acad Sci U S A 2008
23
Clinical similarities and differences of patients with X-linked lymphoproliferative syndrome type 1 (XLP-1/SAP deficiency) versus type 2 (XLP-2/XIAP deficiency).
Jana Pachlopnik Schmid, Danielle Canioni, Despina Moshous, Fabien Touzot, Nizar Mahlaoui, Fabian Hauck, Hirokazu Kanegane, Eduardo Lopez-Granados, Ester Mejstrikova, Isabelle Pellier,[...]. Blood 2011
Jana Pachlopnik Schmid, Danielle Canioni, Despina Moshous, Fabien Touzot, Nizar Mahlaoui, Fabian Hauck, Hirokazu Kanegane, Eduardo Lopez-Granados, Ester Mejstrikova, Isabelle Pellier,[...]. Blood 2011
23
c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation.
Eugene Varfolomeev, Tatiana Goncharov, Anna V Fedorova, Jasmin N Dynek, Kerry Zobel, Kurt Deshayes, Wayne J Fairbrother, Domagoj Vucic. J Biol Chem 2008
Eugene Varfolomeev, Tatiana Goncharov, Anna V Fedorova, Jasmin N Dynek, Kerry Zobel, Kurt Deshayes, Wayne J Fairbrother, Domagoj Vucic. J Biol Chem 2008
22
X-linked IAP is a direct inhibitor of cell-death proteases.
Q L Deveraux, R Takahashi, G S Salvesen, J C Reed. Nature 1997
Q L Deveraux, R Takahashi, G S Salvesen, J C Reed. Nature 1997
20
Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis.
Sean L Petersen, Lai Wang, Asligul Yalcin-Chin, Lin Li, Michael Peyton, John Minna, Patrick Harran, Xiaodong Wang. Cancer Cell 2007
Sean L Petersen, Lai Wang, Asligul Yalcin-Chin, Lin Li, Michael Peyton, John Minna, Patrick Harran, Xiaodong Wang. Cancer Cell 2007
20
IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis.
Mads Gyrd-Hansen, Maurice Darding, Maria Miasari, Massimo M Santoro, Lars Zender, Wen Xue, Tencho Tenev, Paula C A da Fonseca, Marketa Zvelebil, Janusz M Bujnicki,[...]. Nat Cell Biol 2008
Mads Gyrd-Hansen, Maurice Darding, Maria Miasari, Massimo M Santoro, Lars Zender, Wen Xue, Tencho Tenev, Paula C A da Fonseca, Marketa Zvelebil, Janusz M Bujnicki,[...]. Nat Cell Biol 2008
20
XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs.
Fiona L Scott, Jean-Bernard Denault, Stefan J Riedl, Hwain Shin, Martin Renatus, Guy S Salvesen. EMBO J 2005
Fiona L Scott, Jean-Bernard Denault, Stefan J Riedl, Hwain Shin, Martin Renatus, Guy S Salvesen. EMBO J 2005
20
Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines.
Ping-Hui Tseng, Atsushi Matsuzawa, Weizhou Zhang, Takashi Mino, Dario A A Vignali, Michael Karin. Nat Immunol 2010
Ping-Hui Tseng, Atsushi Matsuzawa, Weizhou Zhang, Takashi Mino, Dario A A Vignali, Michael Karin. Nat Immunol 2010
19
The Drosophila inhibitor of apoptosis protein DIAP2 functions in innate immunity and is essential to resist gram-negative bacterial infection.
François Leulier, Nouara Lhocine, Bruno Lemaitre, Pascal Meier. Mol Cell Biol 2006
François Leulier, Nouara Lhocine, Bruno Lemaitre, Pascal Meier. Mol Cell Biol 2006
18
An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif.
N E Crook, R J Clem, L K Miller. J Virol 1993
N E Crook, R J Clem, L K Miller. J Virol 1993
18
Mechanism of XIAP-mediated inhibition of caspase-9.
Eric N Shiozaki, Jijie Chai, Daniel J Rigotti, Stefan J Riedl, Pingwei Li, Srinivasa M Srinivasula, Emad S Alnemri, Robert Fairman, Yigong Shi. Mol Cell 2003
Eric N Shiozaki, Jijie Chai, Daniel J Rigotti, Stefan J Riedl, Pingwei Li, Srinivasa M Srinivasula, Emad S Alnemri, Robert Fairman, Yigong Shi. Mol Cell 2003
18
The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases.
Brendan P Eckelman, Guy S Salvesen. J Biol Chem 2006
Brendan P Eckelman, Guy S Salvesen. J Biol Chem 2006
18
Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction.
Tobias L Haas, Christoph H Emmerich, Björn Gerlach, Anna C Schmukle, Stefanie M Cordier, Eva Rieser, Rebecca Feltham, James Vince, Uwe Warnken, Till Wenger,[...]. Mol Cell 2009
Tobias L Haas, Christoph H Emmerich, Björn Gerlach, Anna C Schmukle, Stefanie M Cordier, Eva Rieser, Rebecca Feltham, James Vince, Uwe Warnken, Till Wenger,[...]. Mol Cell 2009
18
Patients with X-linked lymphoproliferative disease due to BIRC4 mutation have normal invariant natural killer T-cell populations.
Rebecca A Marsh, Joyce Villanueva, Mi-Ok Kim, Kejian Zhang, Dan Marmer, Kimberly A Risma, Michael B Jordan, Jack J Bleesing, Alexandra H Filipovich. Clin Immunol 2009
Rebecca A Marsh, Joyce Villanueva, Mi-Ok Kim, Kejian Zhang, Dan Marmer, Kimberly A Risma, Michael B Jordan, Jack J Bleesing, Alexandra H Filipovich. Clin Immunol 2009
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cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms.
Maria Feoktistova, Peter Geserick, Beate Kellert, Diana Panayotova Dimitrova, Claudia Langlais, Mike Hupe, Kelvin Cain, Marion MacFarlane, Georg Häcker, Martin Leverkus. Mol Cell 2011
Maria Feoktistova, Peter Geserick, Beate Kellert, Diana Panayotova Dimitrova, Claudia Langlais, Mike Hupe, Kelvin Cain, Marion MacFarlane, Georg Häcker, Martin Leverkus. Mol Cell 2011
17
Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family.
Brendan P Eckelman, Guy S Salvesen, Fiona L Scott. EMBO Rep 2006
Brendan P Eckelman, Guy S Salvesen, Fiona L Scott. EMBO Rep 2006
16
TNF-alpha induces two distinct caspase-8 activation pathways.
Lai Wang, Fenghe Du, Xiaodong Wang. Cell 2008
Lai Wang, Fenghe Du, Xiaodong Wang. Cell 2008
16
Structural basis of caspase-7 inhibition by XIAP.
J Chai, E Shiozaki, S M Srinivasula, Q Wu, P Datta, E S Alnemri, Y Shi. Cell 2001
J Chai, E Shiozaki, S M Srinivasula, Q Wu, P Datta, E S Alnemri, Y Shi. Cell 2001
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The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins.
M Rothe, M G Pan, W J Henzel, T M Ayres, D V Goeddel. Cell 1995
M Rothe, M G Pan, W J Henzel, T M Ayres, D V Goeddel. Cell 1995
16
NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2.
Yibin Yang, Catherine Yin, Amit Pandey, Derek Abbott, Christopher Sassetti, Michelle A Kelliher. J Biol Chem 2007
Yibin Yang, Catherine Yin, Amit Pandey, Derek Abbott, Christopher Sassetti, Michelle A Kelliher. J Biol Chem 2007
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Regulation of apoptosis by XIAP ubiquitin-ligase activity.
Andrew J Schile, María García-Fernández, Hermann Steller. Genes Dev 2008
Andrew J Schile, María García-Fernández, Hermann Steller. Genes Dev 2008
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IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer.
Mads Gyrd-Hansen, Pascal Meier. Nat Rev Cancer 2010
Mads Gyrd-Hansen, Pascal Meier. Nat Rev Cancer 2010
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Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease.
J P Hugot, M Chamaillard, H Zouali, S Lesage, J P Cézard, J Belaiche, S Almer, C Tysk, C A O'Morain, M Gassull,[...]. Nature 2001
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The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs.
Tencho Tenev, Katiuscia Bianchi, Maurice Darding, Meike Broemer, Claudia Langlais, Fredrik Wallberg, Anna Zachariou, Juanita Lopez, Marion MacFarlane, Kelvin Cain,[...]. Mol Cell 2011
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XIAP restricts TNF- and RIP3-dependent cell death and inflammasome activation.
Monica Yabal, Nicole Müller, Heiko Adler, Nathalie Knies, Christina J Groß, Rune Busk Damgaard, Hirokazu Kanegane, Marc Ringelhan, Thomas Kaufmann, Mathias Heikenwälder,[...]. Cell Rep 2014
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A Smac mimetic rescue screen reveals roles for inhibitor of apoptosis proteins in tumor necrosis factor-alpha signaling.
Alex Gaither, Dale Porter, Yao Yao, Jason Borawski, Guang Yang, Jerry Donovan, David Sage, Joanna Slisz, Mary Tran, Christopher Straub,[...]. Cancer Res 2007
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Posttranscriptional downregulation of c-IAP2 by the ubiquitin protein ligase c-IAP1 in vivo.
Dietrich B Conze, Lori Albert, David A Ferrick, David V Goeddel, Wen-Chen Yeh, Tak Mak, Jonathan D Ashwell. Mol Cell Biol 2005
Dietrich B Conze, Lori Albert, David A Ferrick, David V Goeddel, Wen-Chen Yeh, Tak Mak, Jonathan D Ashwell. Mol Cell Biol 2005
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Virus-triggered ubiquitination of TRAF3/6 by cIAP1/2 is essential for induction of interferon-beta (IFN-beta) and cellular antiviral response.
Ai-Ping Mao, Shu Li, Bo Zhong, Ying Li, Jie Yan, Qi Li, Chengwen Teng, Hong-Bing Shu. J Biol Chem 2010
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X-linked lymphoproliferative syndromes: brothers or distant cousins?
Alexandra H Filipovich, Kejian Zhang, Andrew L Snow, Rebecca A Marsh. Blood 2010
Alexandra H Filipovich, Kejian Zhang, Andrew L Snow, Rebecca A Marsh. Blood 2010
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A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease.
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Linear ubiquitination prevents inflammation and regulates immune signalling.
Björn Gerlach, Stefanie M Cordier, Anna C Schmukle, Christoph H Emmerich, Eva Rieser, Tobias L Haas, Andrew I Webb, James A Rickard, Holly Anderton, Wendy W-L Wong,[...]. Nature 2011
Björn Gerlach, Stefanie M Cordier, Anna C Schmukle, Christoph H Emmerich, Eva Rieser, Tobias L Haas, Andrew I Webb, James A Rickard, Holly Anderton, Wendy W-L Wong,[...]. Nature 2011
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IAPs limit activation of RIP kinases by TNF receptor 1 during development.
Maryline Moulin, Holly Anderton, Anne K Voss, Tim Thomas, Wendy Wei-Lynn Wong, Aleksandra Bankovacki, Rebecca Feltham, Diep Chau, Wendy D Cook, John Silke,[...]. EMBO J 2012
Maryline Moulin, Holly Anderton, Anne K Voss, Tim Thomas, Wendy Wei-Lynn Wong, Aleksandra Bankovacki, Rebecca Feltham, Diep Chau, Wendy D Cook, John Silke,[...]. EMBO J 2012
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X-linked inhibitor of apoptosis (XIAP) deficiency: the spectrum of presenting manifestations beyond hemophagocytic lymphohistiocytosis.
C Speckmann, K Lehmberg, M H Albert, R B Damgaard, M Fritsch, M Gyrd-Hansen, A Rensing-Ehl, T Vraetz, B Grimbacher, U Salzer,[...]. Clin Immunol 2013
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Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain.
Y Huang, Y C Park, R L Rich, D Segal, D G Myszka, H Wu. Cell 2001
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Structural basis for the inhibition of caspase-3 by XIAP.
S J Riedl, M Renatus, R Schwarzenbacher, Q Zhou, C Sun, S W Fesik, R C Liddington, G S Salvesen. Cell 2001
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13
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.