A citation-based method for searching scientific literature

William W Hauswirth, Tomas S Aleman, Shalesh Kaushal, Artur V Cideciyan, Sharon B Schwartz, Lili Wang, Thomas J Conlon, Sanford L Boye, Terence R Flotte, Barry J Byrne, Samuel G Jacobson. Hum Gene Ther 2008
Times Cited: 725







List of co-cited articles
1372 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Safety and efficacy of gene transfer for Leber's congenital amaurosis.
Albert M Maguire, Francesca Simonelli, Eric A Pierce, Edward N Pugh, Federico Mingozzi, Jeannette Bennicelli, Sandro Banfi, Kathleen A Marshall, Francesco Testa, Enrico M Surace,[...]. N Engl J Med 2008
80

Effect of gene therapy on visual function in Leber's congenital amaurosis.
James W B Bainbridge, Alexander J Smith, Susie S Barker, Scott Robbie, Robert Henderson, Kamaljit Balaggan, Ananth Viswanathan, Graham E Holder, Andrew Stockman, Nick Tyler,[...]. N Engl J Med 2008
77

Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65-mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial.
Stephen Russell, Jean Bennett, Jennifer A Wellman, Daniel C Chung, Zi-Fan Yu, Amy Tillman, Janet Wittes, Julie Pappas, Okan Elci, Sarah McCague,[...]. Lancet 2017
703
43

Long-term effect of gene therapy on Leber's congenital amaurosis.
James W B Bainbridge, Manjit S Mehat, Venki Sundaram, Scott J Robbie, Susie E Barker, Caterina Ripamonti, Anastasios Georgiadis, Freya M Mowat, Stuart G Beattie, Peter J Gardner,[...]. N Engl J Med 2015
455
39

Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial.
Albert M Maguire, Katherine A High, Alberto Auricchio, J Fraser Wright, Eric A Pierce, Francesco Testa, Federico Mingozzi, Jeannette L Bennicelli, Gui-shuang Ying, Settimio Rossi,[...]. Lancet 2009
591
32

Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics.
Artur V Cideciyan, Tomas S Aleman, Sanford L Boye, Sharon B Schwartz, Shalesh Kaushal, Alejandro J Roman, Ji-Jing Pang, Alexander Sumaroka, Elizabeth A M Windsor, James M Wilson,[...]. Proc Natl Acad Sci U S A 2008
538
29

Gene therapy for leber congenital amaurosis caused by RPE65 mutations: safety and efficacy in 15 children and adults followed up to 3 years.
Samuel G Jacobson, Artur V Cideciyan, Ramakrishna Ratnakaram, Elise Heon, Sharon B Schwartz, Alejandro J Roman, Marc C Peden, Tomas S Aleman, Sanford L Boye, Alexander Sumaroka,[...]. Arch Ophthalmol 2012
437
27

Safety and durability of effect of contralateral-eye administration of AAV2 gene therapy in patients with childhood-onset blindness caused by RPE65 mutations: a follow-on phase 1 trial.
Jean Bennett, Jennifer Wellman, Kathleen A Marshall, Sarah McCague, Manzar Ashtari, Julie DiStefano-Pappas, Okan U Elci, Daniel C Chung, Junwei Sun, J Fraser Wright,[...]. Lancet 2016
258
26

Gene therapy restores vision in a canine model of childhood blindness.
G M Acland, G D Aguirre, J Ray, Q Zhang, T S Aleman, A V Cideciyan, S E Pearce-Kelling, V Anand, Y Zeng, A M Maguire,[...]. Nat Genet 2001
862
23

Efficacy, Safety, and Durability of Voretigene Neparvovec-rzyl in RPE65 Mutation-Associated Inherited Retinal Dystrophy: Results of Phase 1 and 3 Trials.
Albert M Maguire, Stephen Russell, Jennifer A Wellman, Daniel C Chung, Zi-Fan Yu, Amy Tillman, Janet Wittes, Julie Pappas, Okan Elci, Kathleen A Marshall,[...]. Ophthalmology 2019
133
23

Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial.
Robert E MacLaren, Markus Groppe, Alun R Barnard, Charles L Cottriall, Tanya Tolmachova, Len Seymour, K Reed Clark, Matthew J During, Frans P M Cremers, Graeme C M Black,[...]. Lancet 2014
520
23

In vivo-directed evolution of a new adeno-associated virus for therapeutic outer retinal gene delivery from the vitreous.
Deniz Dalkara, Leah C Byrne, Ryan R Klimczak, Meike Visel, Lu Yin, William H Merigan, John G Flannery, David V Schaffer. Sci Transl Med 2013
398
23

Safety and Long-Term Efficacy of AAV4 Gene Therapy in Patients with RPE65 Leber Congenital Amaurosis.
Guylène Le Meur, Pierre Lebranchu, Fanny Billaud, Oumeya Adjali, Sébastien Schmitt, Stéphane Bézieau, Yann Péréon, Romain Valabregue, Catherine Ivan, Christophe Darmon,[...]. Mol Ther 2018
63
34

Improvement and decline in vision with gene therapy in childhood blindness.
Samuel G Jacobson, Artur V Cideciyan, Alejandro J Roman, Alexander Sumaroka, Sharon B Schwartz, Elise Heon, William W Hauswirth. N Engl J Med 2015
243
20

Human retinal gene therapy for Leber congenital amaurosis shows advancing retinal degeneration despite enduring visual improvement.
Artur V Cideciyan, Samuel G Jacobson, William A Beltran, Alexander Sumaroka, Malgorzata Swider, Simone Iwabe, Alejandro J Roman, Melani B Olivares, Sharon B Schwartz, András M Komáromy,[...]. Proc Natl Acad Sci U S A 2013
299
18

Three-year follow-up after unilateral subretinal delivery of adeno-associated virus in patients with Leber congenital Amaurosis type 2.
Francesco Testa, Albert M Maguire, Settimio Rossi, Eric A Pierce, Paolo Melillo, Kathleen Marshall, Sandro Banfi, Enrico M Surace, Junwei Sun, Carmela Acerra,[...]. Ophthalmology 2013
224
18

AAV2 gene therapy readministration in three adults with congenital blindness.
Jean Bennett, Manzar Ashtari, Jennifer Wellman, Kathleen A Marshall, Laura L Cyckowski, Daniel C Chung, Sarah McCague, Eric A Pierce, Yifeng Chen, Jeannette L Bennicelli,[...]. Sci Transl Med 2012
282
18

Results at 2 Years after Gene Therapy for RPE65-Deficient Leber Congenital Amaurosis and Severe Early-Childhood-Onset Retinal Dystrophy.
Richard G Weleber, Mark E Pennesi, David J Wilson, Shalesh Kaushal, Laura R Erker, Lauren Jensen, Maureen T McBride, Terence R Flotte, Margaret Humphries, Roberto Calcedo,[...]. Ophthalmology 2016
112
17

Retinal AAV8-RS1 Gene Therapy for X-Linked Retinoschisis: Initial Findings from a Phase I/IIa Trial by Intravitreal Delivery.
Catherine Cukras, Henry E Wiley, Brett G Jeffrey, H Nida Sen, Amy Turriff, Yong Zeng, Camasamudram Vijayasarathy, Dario Marangoni, Lucia Ziccardi, Sten Kjellstrom,[...]. Mol Ther 2018
99
17

Long-term restoration of rod and cone vision by single dose rAAV-mediated gene transfer to the retina in a canine model of childhood blindness.
Gregory M Acland, Gustavo D Aguirre, Jean Bennett, Tomas S Aleman, Artur V Cideciyan, Jeannette Bennicelli, Nadine S Dejneka, Susan E Pearce-Kelling, Albert M Maguire, Krzysztof Palczewski,[...]. Mol Ther 2005
338
16

Gene Therapy for Leber Hereditary Optic Neuropathy: Low- and Medium-Dose Visual Results.
John Guy, William J Feuer, Janet L Davis, Vittorio Porciatti, Phillip J Gonzalez, Rajeshwari D Koilkonda, Huijun Yuan, William W Hauswirth, Byron L Lam. Ophthalmology 2017
104
15

Adenovirus-associated virus vector-mediated gene transfer in hemophilia B.
Amit C Nathwani, Edward G D Tuddenham, Savita Rangarajan, Cecilia Rosales, Jenny McIntosh, David C Linch, Pratima Chowdary, Anne Riddell, Arnulfo Jaquilmac Pie, Chris Harrington,[...]. N Engl J Med 2011
15

Antibody neutralization poses a barrier to intravitreal adeno-associated viral vector gene delivery to non-human primates.
M A Kotterman, L Yin, J M Strazzeri, J G Flannery, W H Merigan, D V Schaffer. Gene Ther 2015
104
15

Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina.
Hilda Petrs-Silva, Astra Dinculescu, Qiuhong Li, Wen-Tao Deng, Ji-Jing Pang, Seok-Hong Min, Vince Chiodo, Andy W Neeley, Lakshmanan Govindasamy, Antonette Bennett,[...]. Mol Ther 2011
182
15

Leber congenital amaurosis: genes, proteins and disease mechanisms.
Anneke I den Hollander, Ronald Roepman, Robert K Koenekoop, Frans P M Cremers. Prog Retin Eye Res 2008
543
15

Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration.
Francesca Simonelli, Albert M Maguire, Francesco Testa, Eric A Pierce, Federico Mingozzi, Jeannette L Bennicelli, Settimio Rossi, Kathleen Marshall, Sandro Banfi, Enrico M Surace,[...]. Mol Ther 2010
386
15

Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle.
T M Redmond, S Yu, E Lee, D Bok, D Hamasaki, N Chen, P Goletz, J X Ma, R K Crouch, K Pfeifer. Nat Genet 1998
743
14

Treatment of retinitis pigmentosa due to MERTK mutations by ocular subretinal injection of adeno-associated virus gene vector: results of a phase I trial.
Nicola G Ghazi, Emad B Abboud, Sawsan R Nowilaty, Hisham Alkuraya, Abdulrahman Alhommadi, Huimin Cai, Rui Hou, Wen-Tao Deng, Sanford L Boye, Abdulrahman Almaghamsi,[...]. Hum Genet 2016
140
14

Gene Therapy for Leber Hereditary Optic Neuropathy: Initial Results.
William J Feuer, Joyce C Schiffman, Janet L Davis, Vittorio Porciatti, Phillip Gonzalez, Rajeshwari D Koilkonda, Huijun Yuan, Anil Lalwani, Byron L Lam, John Guy. Ophthalmology 2016
140
14

Single-Dose Gene-Replacement Therapy for Spinal Muscular Atrophy.
Jerry R Mendell, Samiah Al-Zaidy, Richard Shell, W Dave Arnold, Louise R Rodino-Klapac, Thomas W Prior, Linda Lowes, Lindsay Alfano, Katherine Berry, Kathleen Church,[...]. N Engl J Med 2017
966
14

Initial results from a first-in-human gene therapy trial on X-linked retinitis pigmentosa caused by mutations in RPGR.
Jasmina Cehajic-Kapetanovic, Kanmin Xue, Cristina Martinez-Fernandez de la Camara, Anika Nanda, Alexandra Davies, Laura J Wood, Anna Paola Salvetti, M Dominik Fischer, James W Aylward, Alun R Barnard,[...]. Nat Med 2020
102
14

Identifying photoreceptors in blind eyes caused by RPE65 mutations: Prerequisite for human gene therapy success.
Samuel G Jacobson, Tomas S Aleman, Artur V Cideciyan, Alexander Sumaroka, Sharon B Schwartz, Elizabeth A M Windsor, Elias I Traboulsi, Elise Heon, Steven J Pittler, Ann H Milam,[...]. Proc Natl Acad Sci U S A 2005
210
13

Efficacy and Safety of Retinal Gene Therapy Using Adeno-Associated Virus Vector for Patients With Choroideremia: A Randomized Clinical Trial.
M Dominik Fischer, G Alex Ochakovski, Benjamin Beier, Immanuel P Seitz, Yousof Vaheb, Constanze Kortuem, Felix F L Reichel, Laura Kuehlewein, Nadine A Kahle, Tobias Peters,[...]. JAMA Ophthalmol 2019
40
32

Two-Year Results After AAV2-Mediated Gene Therapy for Choroideremia: The Alberta Experience.
Ioannis S Dimopoulos, Stephanie C Hoang, Alina Radziwon, Natalia M Binczyk, Miguel C Seabra, Robert E MacLaren, Rizwan Somani, Matthew T S Tennant, Ian M MacDonald. Am J Ophthalmol 2018
84
15

Effect of an intravitreal antisense oligonucleotide on vision in Leber congenital amaurosis due to a photoreceptor cilium defect.
Artur V Cideciyan, Samuel G Jacobson, Arlene V Drack, Allen C Ho, Jason Charng, Alexandra V Garafalo, Alejandro J Roman, Alexander Sumaroka, Ian C Han, Maria D Hochstedler,[...]. Nat Med 2019
117
13

Intraocular route of AAV2 vector administration defines humoral immune response and therapeutic potential.
Qiuhong Li, Rehae Miller, Ping-Yang Han, Jijing Pang, Astra Dinculescu, Vince Chiodo, William W Hauswirth. Mol Vis 2008
135
13

AAV8-vectored suprachoroidal gene transfer produces widespread ocular transgene expression.
Kun Ding, Jikui Shen, Zibran Hafiz, Sean F Hackett, Raquel Lima E Silva, Mahmood Khan, Valeria E Lorenc, Daiqin Chen, Rishi Chadha, Minie Zhang,[...]. J Clin Invest 2019
48
25

Human RPE65 gene therapy for Leber congenital amaurosis: persistence of early visual improvements and safety at 1 year.
Artur V Cideciyan, William W Hauswirth, Tomas S Aleman, Shalesh Kaushal, Sharon B Schwartz, Sanford L Boye, Elizabeth A M Windsor, Thomas J Conlon, Alexander Sumaroka, Ji-Jing Pang,[...]. Hum Gene Ther 2009
246
12

RPE65 is the isomerohydrolase in the retinoid visual cycle.
Gennadiy Moiseyev, Ying Chen, Yusuke Takahashi, Bill X Wu, Jian-Xing Ma. Proc Natl Acad Sci U S A 2005
383
12

Safety and Vision Outcomes of Subretinal Gene Therapy Targeting Cone Photoreceptors in Achromatopsia: A Nonrandomized Controlled Trial.
M Dominik Fischer, Stylianos Michalakis, Barbara Wilhelm, Ditta Zobor, Regine Muehlfriedel, Susanne Kohl, Nicole Weisschuh, G Alex Ochakovski, Reinhild Klein, Christian Schoen,[...]. JAMA Ophthalmol 2020
47
25


Choroideremia Gene Therapy Phase 2 Clinical Trial: 24-Month Results.
Byron L Lam, Janet L Davis, Ninel Z Gregori, Robert E MacLaren, Aniz Girach, Jennifer D Verriotto, Belen Rodriguez, Potyra R Rosa, Xiaojun Zhang, William J Feuer. Am J Ophthalmol 2019
78
14

Long-term safety and efficacy of factor IX gene therapy in hemophilia B.
Amit C Nathwani, Ulreke M Reiss, Edward G D Tuddenham, Cecilia Rosales, Pratima Chowdary, Jenny McIntosh, Marco Della Peruta, Elsa Lheriteau, Nishal Patel, Deepak Raj,[...]. N Engl J Med 2014
749
11

Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous.
Deniz Dalkara, Kathleen D Kolstad, Natalia Caporale, Meike Visel, Ryan R Klimczak, David V Schaffer, John G Flannery. Mol Ther 2009
190
11

Adeno-associated virus vector as a platform for gene therapy delivery.
Dan Wang, Phillip W L Tai, Guangping Gao. Nat Rev Drug Discov 2019
527
11

Suprachoroidal and Subretinal Injections of AAV Using Transscleral Microneedles for Retinal Gene Delivery in Nonhuman Primates.
Glenn Yiu, Sook Hyun Chung, Iris N Mollhoff, Uyen Tu Nguyen, Sara M Thomasy, Jesse Yoo, Donna Taraborelli, Glenn Noronha. Mol Ther Methods Clin Dev 2020
39
28

Restoration of vision in RPE65-deficient Briard dogs using an AAV serotype 4 vector that specifically targets the retinal pigmented epithelium.
G Le Meur, K Stieger, A J Smith, M Weber, J Y Deschamps, D Nivard, A Mendes-Madeira, N Provost, Y Péréon, Y Cherel,[...]. Gene Ther 2007
145
10

Defining the residual vision in leber congenital amaurosis caused by RPE65 mutations.
Samuel G Jacobson, Tomas S Aleman, Artur V Cideciyan, Alejandro J Roman, Alexander Sumaroka, Elizabeth A M Windsor, Sharon B Schwartz, Elise Heon, Edwin M Stone. Invest Ophthalmol Vis Sci 2009
96
10

Results at 5 Years After Gene Therapy for RPE65-Deficient Retinal Dystrophy.
Mark E Pennesi, Richard G Weleber, Paul Yang, Chris Whitebirch, Beverly Thean, Terence R Flotte, Margaret Humphries, Elvira Chegarnov, Kathleen N Beasley, J Timothy Stout,[...]. Hum Gene Ther 2018
26
38

Safety and efficacy of subretinal readministration of a viral vector in large animals to treat congenital blindness.
Defne Amado, Federico Mingozzi, Daniel Hui, Jeannette L Bennicelli, Zhangyong Wei, Yifeng Chen, Erin Bote, Rebecca L Grant, Jeffrey A Golden, Kristina Narfstrom,[...]. Sci Transl Med 2010
90
11


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.