A citation-based method for searching scientific literature

Kanako Sakuyama, Takamitsu Sasaki, Shuta Ujiie, Kanako Obata, Michinao Mizugaki, Masaaki Ishikawa, Masahiro Hiratsuka. Drug Metab Dispos 2008
Times Cited: 122







List of co-cited articles
896 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity






Crystal structure of human cytochrome P450 2D6.
Paul Rowland, Frank E Blaney, Martin G Smyth, Jo J Jones, Vaughan R Leydon, Amanda K Oxbrow, Ceri J Lewis, Mike G Tennant, Sandeep Modi, Drake S Eggleston,[...]. J Biol Chem 2006
338
20


A combination of mutations in the CYP2D6*17 (CYP2D6Z) allele causes alterations in enzyme function.
M Oscarson, M Hidestrand, I Johansson, M Ingelman-Sundberg. Mol Pharmacol 1997
120
19

Comparative metabolic capabilities and inhibitory profiles of CYP2D6.1, CYP2D6.10, and CYP2D6.17.
Hongwu Shen, Minxia M He, Houfu Liu, Steven A Wrighton, Li Wang, Bin Guo, Chuan Li. Drug Metab Dispos 2007
126
18

Functional characterization of wild-type and 49 CYP2D6 allelic variants for N-desmethyltamoxifen 4-hydroxylation activity.
Yuka Muroi, Takahiro Saito, Masamitsu Takahashi, Kanako Sakuyama, Yui Niinuma, Miyabi Ito, Chiharu Tsukada, Kiminori Ohta, Yasuyuki Endo, Akifumi Oda,[...]. Drug Metab Pharmacokinet 2014
33
54

Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry.
Ulrich M Zanger, Sebastian Raimundo, Michel Eichelbaum. Naunyn Schmiedebergs Arch Pharmacol 2004
587
17


Characterization of cytochrome P450 2D6.1 (CYP2D6.1), CYP2D6.2, and CYP2D6.17 activities toward model CYP2D6 substrates dextromethorphan, bufuralol, and debrisoquine.
Kenda A Marcucci, Robin E Pearce, Charles Crespi, Dorothy T Steimel, J Steven Leeder, Andrea Gaedigk. Drug Metab Dispos 2002
49
34

Characterization of the CYP2D6*29 allele commonly present in a black Tanzanian population causing reduced catalytic activity.
A Wennerholm, I Johansson, M Hidestrand, L Bertilsson, L L Gustafsson, M Ingelman-Sundberg. Pharmacogenetics 2001
66
24

Influence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects.
Magnus Ingelman-Sundberg, Sarah C Sim, Alvin Gomez, Cristina Rodriguez-Antona. Pharmacol Ther 2007
776
16

The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype.
A Gaedigk, S D Simon, R E Pearce, L D Bradford, M J Kennedy, J S Leeder. Clin Pharmacol Ther 2008
518
16


Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: characterization of 48 mutations and 53 alleles, their frequencies and evolution.
D Marez, M Legrand, N Sabbagh, J M Lo Guidice, C Spire, J J Lafitte, U A Meyer, F Broly. Pharmacogenetics 1997
314
14


Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine.
I Johansson, E Lundqvist, L Bertilsson, M L Dahl, F Sjöqvist, M Ingelman-Sundberg. Proc Natl Acad Sci U S A 1993
542
13


In vitro assessment of the allelic variants of cytochrome P450.
Masahiro Hiratsuka. Drug Metab Pharmacokinet 2012
89
14

A novel intronic mutation, 2988G>A, with high predictivity for impaired function of cytochrome P450 2D6 in white subjects.
Sebastian Raimundo, Claudia Toscano, Kathrin Klein, Joachim Fischer, Ernst-Ulrich Griese, Michel Eichelbaum, Matthias Schwab, Ulrich M Zanger. Clin Pharmacol Ther 2004
140
12


Genetic variations of human CYP2D6 in the Chinese Han population.
Jian-Chang Qian, Xin-Min Xu, Guo-Xin Hu, Da-Peng Dai, Ren-Ai Xu, Li-Ming Hu, Fang-Hong Li, Xiu-Hua Zhang, Jie-Fu Yang, Jian-Ping Cai. Pharmacogenomics 2013
48
22

Impaired expression of CYP2D6 in intermediate metabolizers carrying the *41 allele caused by the intronic SNP 2988G>A: evidence for modulation of splicing events.
Claudia Toscano, Kathrin Klein, Julia Blievernicht, Elke Schaeffeler, Tanja Saussele, Sebastian Raimundo, Michel Eichelbaum, Matthias Schwab, Ulrich M Zanger. Pharmacogenet Genomics 2006
70
14

Discovery of novel functional variants and extensive evaluation of CYP2D6 genetic polymorphisms in Koreans.
Su-Jun Lee, Sang Seop Lee, Hyun-Ju Jung, Ho-Sook Kim, Soo-Jin Park, Chang-Woo Yeo, Jae-Gook Shin. Drug Metab Dispos 2009
55
18

Frequent distribution of ultrarapid metabolizers of debrisoquine in an ethiopian population carrying duplicated and multiduplicated functional CYP2D6 alleles.
E Aklillu, I Persson, L Bertilsson, I Johansson, F Rodrigues, M Ingelman-Sundberg. J Pharmacol Exp Ther 1996
306
10

Detection of the poor metabolizer-associated CYP2D6(D) gene deletion allele by long-PCR technology.
V M Steen, O A Andreassen, A K Daly, T Tefre, A L Børresen, J R Idle, A K Gulbrandsen. Pharmacogenetics 1995
241
10


CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer: the breast international group 1-98 trial.
Meredith M Regan, Brian Leyland-Jones, Mark Bouzyk, Olivia Pagani, Weining Tang, Roswitha Kammler, Patrizia Dell'orto, Maria Olivia Biasi, Beat Thürlimann, Maria B Lyng,[...]. J Natl Cancer Inst 2012
238
10

Elucidation of the genetic basis of the common 'intermediate metabolizer' phenotype for drug oxidation by CYP2D6.
S Raimundo, J Fischer, M Eichelbaum, E U Griese, M Schwab, U M Zanger. Pharmacogenetics 2000
156
10

Common CYP2D6 polymorphisms affecting alternative splicing and transcription: long-range haplotypes with two regulatory variants modulate CYP2D6 activity.
Danxin Wang, Ming J Poi, Xiaochun Sun, Andrea Gaedigk, J Steven Leeder, Wolfgang Sadee. Hum Mol Genet 2014
74
13

Interethnic variability of CYP2D6 alleles and of predicted and measured metabolic phenotypes across world populations.
Adrián LLerena, Maria Eugenia G Naranjo, Fernanda Rodrigues-Soares, Eva M Penas-LLedó, Humberto Fariñas, Eduardo Tarazona-Santos. Expert Opin Drug Metab Toxicol 2014
100
10

Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450 2D6 genotype and codeine therapy: 2014 update.
K R Crews, A Gaedigk, H M Dunnenberger, J S Leeder, T E Klein, K E Caudle, C E Haidar, D D Shen, J T Callaghan, S Sadhasivam,[...]. Clin Pharmacol Ther 2014
407
10


Identification of the primary gene defect at the cytochrome P450 CYP2D locus.
A C Gough, J S Miles, N K Spurr, J E Moss, A Gaedigk, M Eichelbaum, C R Wolf. Nature 1990
318
9


Two novel CYP2D6*10 haplotypes as possible causes of a poor metabolic phenotype in Japanese.
Masayuki Matsunaga, Hiroshi Yamazaki, Kazuma Kiyotani, Shunsuke Iwano, Jyunji Saruwatari, Kazuko Nakagawa, Akiko Soyama, Shogo Ozawa, Jun-Ichi Sawada, Eiji Kashiyama,[...]. Drug Metab Dispos 2009
23
39


Systematic polymorphism analysis of the CYP2D6 gene in four different geographical Han populations in mainland China.
Shengying Qin, Lu Shen, Aiping Zhang, Jing Xie, Wen Shen, Lingling Chen, Jimin Tang, Yuyu Xiong, Lun Yang, Yongyong Shi,[...]. Genomics 2008
50
18


Clinical Pharmacogenetics Implementation Consortium guideline for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants.
J K Hicks, J J Swen, C F Thorn, K Sangkuhl, E D Kharasch, V L Ellingrod, T C Skaar, D J Müller, A Gaedigk, J C Stingl. Clin Pharmacol Ther 2013
287
9

Molecular genetics of CYP2D6: clinical relevance with focus on psychotropic drugs.
Leif Bertilsson, Marja-Liisa Dahl, Per Dalén, Ayman Al-Shurbaji. Br J Clin Pharmacol 2002
356
9

Complexities of CYP2D6 gene analysis and interpretation.
Andrea Gaedigk. Int Rev Psychiatry 2013
140
9



Prediction of CYP2D6 phenotype from genotype across world populations.
Andrea Gaedigk, Katrin Sangkuhl, Michelle Whirl-Carrillo, Teri Klein, J Steven Leeder. Genet Med 2017
255
9

CYP2D6*36 gene arrangements within the cyp2d6 locus: association of CYP2D6*36 with poor metabolizer status.
Andrea Gaedigk, L Dianne Bradford, Sarah W Alander, J Steven Leeder. Drug Metab Dispos 2006
72
11

Comprehensive analysis of the genetic factors determining expression and function of hepatic CYP2D6.
U M Zanger, J Fischer, S Raimundo, T Stüven, B O Evert, M Schwab, M Eichelbaum. Pharmacogenetics 2001
203
8

CYP2D6.10 present in human liver microsomes shows low catalytic activity and thermal stability.
Katsunori Nakamura, Noritaka Ariyoshi, Tsuyoshi Yokoi, Satoru Ohgiya, Michihiro Chida, Kazuo Nagashima, Kazuaki Inoue, Takao Kodama, Noriaki Shimada, Tetsuya Kamataki. Biochem Biophys Res Commun 2002
38
21


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.