Heng Du, Lan Guo, Fang Fang, Doris Chen, Alexander A Sosunov, Guy M McKhann, Yilin Yan, Chunyu Wang, Hong Zhang, Jeffery D Molkentin, Frank J Gunn-Moore, Jean Paul Vonsattel, Ottavio Arancio, John Xi Chen, Shi Du Yan. Nat Med 2008
Times Cited: 669
Times Cited: 669
Times Cited
Times Co-cited
Similarity
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.
Joyce W Lustbader, Maurizio Cirilli, Chang Lin, Hong Wei Xu, Kazuhiro Takuma, Ning Wang, Casper Caspersen, Xi Chen, Susan Pollak, Michael Chaney,[...]. Science 2004
Joyce W Lustbader, Maurizio Cirilli, Chang Lin, Hong Wei Xu, Kazuhiro Takuma, Ning Wang, Casper Caspersen, Xi Chen, Susan Pollak, Michael Chaney,[...]. Science 2004
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Cyclophilin D deficiency improves mitochondrial function and learning/memory in aging Alzheimer disease mouse model.
Heng Du, Lan Guo, Wensheng Zhang, Monika Rydzewska, Shidu Yan. Neurobiol Aging 2011
Heng Du, Lan Guo, Wensheng Zhang, Monika Rydzewska, Shidu Yan. Neurobiol Aging 2011
23
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death.
Christopher P Baines, Robert A Kaiser, Nicole H Purcell, N Scott Blair, Hanna Osinska, Michael A Hambleton, Eric W Brunskill, M Richard Sayen, Roberta A Gottlieb, Gerald W Dorn,[...]. Nature 2005
Christopher P Baines, Robert A Kaiser, Nicole H Purcell, N Scott Blair, Hanna Osinska, Michael A Hambleton, Eric W Brunskill, M Richard Sayen, Roberta A Gottlieb, Gerald W Dorn,[...]. Nature 2005
22
Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression.
Maria Manczak, Thimmappa S Anekonda, Edward Henson, Byung S Park, Joseph Quinn, P Hemachandra Reddy. Hum Mol Genet 2006
Maria Manczak, Thimmappa S Anekonda, Edward Henson, Byung S Park, Joseph Quinn, P Hemachandra Reddy. Hum Mol Genet 2006
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Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage.
Maria Manczak, Marcus J Calkins, P Hemachandra Reddy. Hum Mol Genet 2011
Maria Manczak, Marcus J Calkins, P Hemachandra Reddy. Hum Mol Genet 2011
18
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease.
Xinglong Wang, Bo Su, Hyoung-gon Lee, Xinyi Li, George Perry, Mark A Smith, Xiongwei Zhu. J Neurosci 2009
Xinglong Wang, Bo Su, Hyoung-gon Lee, Xinyi Li, George Perry, Mark A Smith, Xiongwei Zhu. J Neurosci 2009
18
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.
Evandro F Fang, Yujun Hou, Konstantinos Palikaras, Bryan A Adriaanse, Jesse S Kerr, Beimeng Yang, Sofie Lautrup, Md Mahdi Hasan-Olive, Domenica Caponio, Xiuli Dan,[...]. Nat Neurosci 2019
Evandro F Fang, Yujun Hou, Konstantinos Palikaras, Bryan A Adriaanse, Jesse S Kerr, Beimeng Yang, Sofie Lautrup, Md Mahdi Hasan-Olive, Domenica Caponio, Xiuli Dan,[...]. Nat Neurosci 2019
17
The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae.
Camilla A Hansson Petersen, Nyosha Alikhani, Homira Behbahani, Birgitta Wiehager, Pavel F Pavlov, Irina Alafuzoff, Ville Leinonen, Akira Ito, Bengt Winblad, Elzbieta Glaser,[...]. Proc Natl Acad Sci U S A 2008
Camilla A Hansson Petersen, Nyosha Alikhani, Homira Behbahani, Birgitta Wiehager, Pavel F Pavlov, Irina Alafuzoff, Ville Leinonen, Akira Ito, Bengt Winblad, Elzbieta Glaser,[...]. Proc Natl Acad Sci U S A 2008
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Mitochondria and Mitochondrial Cascades in Alzheimer's Disease.
Russell H Swerdlow. J Alzheimers Dis 2018
Russell H Swerdlow. J Alzheimers Dis 2018
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Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease.
Casper Caspersen, Ning Wang, Jun Yao, Alexander Sosunov, Xi Chen, Joyce W Lustbader, Hong Wei Xu, David Stern, Guy McKhann, Shi Du Yan. FASEB J 2005
Casper Caspersen, Ning Wang, Jun Yao, Alexander Sosunov, Xi Chen, Joyce W Lustbader, Hong Wei Xu, David Stern, Guy McKhann, Shi Du Yan. FASEB J 2005
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Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease.
Jia Yao, Ronald W Irwin, Liqin Zhao, Jon Nilsen, Ryan T Hamilton, Roberta Diaz Brinton. Proc Natl Acad Sci U S A 2009
Jia Yao, Ronald W Irwin, Liqin Zhao, Jon Nilsen, Ryan T Hamilton, Roberta Diaz Brinton. Proc Natl Acad Sci U S A 2009
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Impaired mitochondrial calcium efflux contributes to disease progression in models of Alzheimer's disease.
Pooja Jadiya, Devin W Kolmetzky, Dhanendra Tomar, Antonio Di Meco, Alyssa A Lombardi, Jonathan P Lambert, Timothy S Luongo, Marthe H Ludtmann, Domenico Praticò, John W Elrod. Nat Commun 2019
Pooja Jadiya, Devin W Kolmetzky, Dhanendra Tomar, Antonio Di Meco, Alyssa A Lombardi, Jonathan P Lambert, Timothy S Luongo, Marthe H Ludtmann, Domenico Praticò, John W Elrod. Nat Commun 2019
15
Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins.
Xinglong Wang, Bo Su, Sandra L Siedlak, Paula I Moreira, Hisashi Fujioka, Yang Wang, Gemma Casadesus, Xiongwei Zhu. Proc Natl Acad Sci U S A 2008
Xinglong Wang, Bo Su, Sandra L Siedlak, Paula I Moreira, Hisashi Fujioka, Yang Wang, Gemma Casadesus, Xiongwei Zhu. Proc Natl Acad Sci U S A 2008
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The Alzheimer's disease mitochondrial cascade hypothesis: progress and perspectives.
Russell H Swerdlow, Jeffrey M Burns, Shaharyar M Khan. Biochim Biophys Acta 2014
Russell H Swerdlow, Jeffrey M Burns, Shaharyar M Khan. Biochim Biophys Acta 2014
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Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage.
Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2012
Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2012
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Mitochondrial abnormalities in Alzheimer's disease.
K Hirai, G Aliev, A Nunomura, H Fujioka, R L Russell, C S Atwood, A B Johnson, Y Kress, H V Vinters, M Tabaton,[...]. J Neurosci 2001
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Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease.
P Hemachandra Reddy, M Flint Beal. Trends Mol Med 2008
P Hemachandra Reddy, M Flint Beal. Trends Mol Med 2008
13
Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice.
Virginie Rhein, Xiaomin Song, Andreas Wiesner, Lars M Ittner, Ginette Baysang, Fides Meier, Laurence Ozmen, Horst Bluethmann, Stefan Dröse, Ulrich Brandt,[...]. Proc Natl Acad Sci U S A 2009
Virginie Rhein, Xiaomin Song, Andreas Wiesner, Lars M Ittner, Ginette Baysang, Fides Meier, Laurence Ozmen, Horst Bluethmann, Stefan Dröse, Ulrich Brandt,[...]. Proc Natl Acad Sci U S A 2009
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Mitophagy and Alzheimer's Disease: Cellular and Molecular Mechanisms.
Jesse S Kerr, Bryan A Adriaanse, Nigel H Greig, Mark P Mattson, M Zameel Cader, Vilhelm A Bohr, Evandro F Fang. Trends Neurosci 2017
Jesse S Kerr, Bryan A Adriaanse, Nigel H Greig, Mark P Mattson, M Zameel Cader, Vilhelm A Bohr, Evandro F Fang. Trends Neurosci 2017
13
Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer's disease.
Simon J Beck, Lan Guo, Aarron Phensy, Jing Tian, Lu Wang, Neha Tandon, Esha Gauba, Lin Lu, Juan M Pascual, Sven Kroener,[...]. Nat Commun 2016
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15
Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction.
Latha Devi, Badanavalu M Prabhu, Domenico F Galati, Narayan G Avadhani, Hindupur K Anandatheerthavarada. J Neurosci 2006
Latha Devi, Badanavalu M Prabhu, Domenico F Galati, Narayan G Avadhani, Hindupur K Anandatheerthavarada. J Neurosci 2006
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A "mitochondrial cascade hypothesis" for sporadic Alzheimer's disease.
Russell H Swerdlow, Shaharyar M Khan. Med Hypotheses 2004
Russell H Swerdlow, Shaharyar M Khan. Med Hypotheses 2004
12
An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore.
Kambiz N Alavian, Gisela Beutner, Emma Lazrove, Silvio Sacchetti, Han-A Park, Pawel Licznerski, Hongmei Li, Panah Nabili, Kathryn Hockensmith, Morven Graham,[...]. Proc Natl Acad Sci U S A 2014
Kambiz N Alavian, Gisela Beutner, Emma Lazrove, Silvio Sacchetti, Han-A Park, Pawel Licznerski, Hongmei Li, Panah Nabili, Kathryn Hockensmith, Morven Graham,[...]. Proc Natl Acad Sci U S A 2014
12
Dimers of mitochondrial ATP synthase form the permeability transition pore.
Valentina Giorgio, Sophia von Stockum, Manuela Antoniel, Astrid Fabbro, Federico Fogolari, Michael Forte, Gary D Glick, Valeria Petronilli, Mario Zoratti, Ildikó Szabó,[...]. Proc Natl Acad Sci U S A 2013
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Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease.
Marcus J Calkins, Maria Manczak, Peizhong Mao, Ulziibat Shirendeb, P Hemachandra Reddy. Hum Mol Genet 2011
Marcus J Calkins, Maria Manczak, Peizhong Mao, Ulziibat Shirendeb, P Hemachandra Reddy. Hum Mol Genet 2011
11
Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease.
Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2012
Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2012
11
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases.
Michael T Lin, M Flint Beal. Nature 2006
Michael T Lin, M Flint Beal. Nature 2006
11
A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter.
Diego De Stefani, Anna Raffaello, Enrico Teardo, Ildikò Szabò, Rosario Rizzuto. Nature 2011
Diego De Stefani, Anna Raffaello, Enrico Teardo, Ildikò Szabò, Rosario Rizzuto. Nature 2011
11
Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia.
Anna C Schinzel, Osamu Takeuchi, Zhihong Huang, Jill K Fisher, Zhipeng Zhou, Jeffery Rubens, Claudio Hetz, Nika N Danial, Michael A Moskowitz, Stanley J Korsmeyer. Proc Natl Acad Sci U S A 2005
Anna C Schinzel, Osamu Takeuchi, Zhihong Huang, Jill K Fisher, Zhipeng Zhou, Jeffery Rubens, Claudio Hetz, Nika N Danial, Michael A Moskowitz, Stanley J Korsmeyer. Proc Natl Acad Sci U S A 2005
11
Hippocampal mutant APP and amyloid beta-induced cognitive decline, dendritic spine loss, defective autophagy, mitophagy and mitochondrial abnormalities in a mouse model of Alzheimer's disease.
Maria Manczak, Ramesh Kandimalla, Xiangling Yin, P Hemachandra Reddy. Hum Mol Genet 2018
Maria Manczak, Ramesh Kandimalla, Xiangling Yin, P Hemachandra Reddy. Hum Mol Genet 2018
11
PINK1 signalling rescues amyloid pathology and mitochondrial dysfunction in Alzheimer's disease.
Fang Du, Qing Yu, Shijun Yan, Gang Hu, Lih-Fen Lue, Douglas G Walker, Long Wu, Shi Fang Yan, Kim Tieu, Shirley ShiDu Yan. Brain 2017
Fang Du, Qing Yu, Shijun Yan, Gang Hu, Lih-Fen Lue, Douglas G Walker, Long Wu, Shi Fang Yan, Kim Tieu, Shirley ShiDu Yan. Brain 2017
10
Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D.
Emy Basso, Lisa Fante, Jonathan Fowlkes, Valeria Petronilli, Michael A Forte, Paolo Bernardi. J Biol Chem 2005
Emy Basso, Lisa Fante, Jonathan Fowlkes, Valeria Petronilli, Michael A Forte, Paolo Bernardi. J Biol Chem 2005
10
Cyclophilin D Promotes Brain Mitochondrial F1FO ATP Synthase Dysfunction in Aging Mice.
Esha Gauba, Lan Guo, Heng Du. J Alzheimers Dis 2017
Esha Gauba, Lan Guo, Heng Du. J Alzheimers Dis 2017
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Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model.
Heng Du, Lan Guo, Shiqiang Yan, Alexander A Sosunov, Guy M McKhann, Shirley ShiDu Yan. Proc Natl Acad Sci U S A 2010
Heng Du, Lan Guo, Shiqiang Yan, Alexander A Sosunov, Guy M McKhann, Shirley ShiDu Yan. Proc Natl Acad Sci U S A 2010
10
Purified F-ATP synthase forms a Ca2+-dependent high-conductance channel matching the mitochondrial permeability transition pore.
Andrea Urbani, Valentina Giorgio, Andrea Carrer, Cinzia Franchin, Giorgio Arrigoni, Chimari Jiko, Kazuhiro Abe, Shintaro Maeda, Kyoko Shinzawa-Itoh, Janna F M Bogers,[...]. Nat Commun 2019
Andrea Urbani, Valentina Giorgio, Andrea Carrer, Cinzia Franchin, Giorgio Arrigoni, Chimari Jiko, Kazuhiro Abe, Shintaro Maeda, Kyoko Shinzawa-Itoh, Janna F M Bogers,[...]. Nat Commun 2019
10
Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD.
Jason Karch, Michael J Bround, Hadi Khalil, Michelle A Sargent, Nadina Latchman, Naohiro Terada, Pablo M Peixoto, Jeffery D Molkentin. Sci Adv 2019
Jason Karch, Michael J Bround, Hadi Khalil, Michelle A Sargent, Nadina Latchman, Naohiro Terada, Pablo M Peixoto, Jeffery D Molkentin. Sci Adv 2019
11
NCLX is an essential component of mitochondrial Na+/Ca2+ exchange.
Raz Palty, William F Silverman, Michal Hershfinkel, Teresa Caporale, Stefano L Sensi, Julia Parnis, Christiane Nolte, Daniel Fishman, Varda Shoshan-Barmatz, Sharon Herrmann,[...]. Proc Natl Acad Sci U S A 2010
Raz Palty, William F Silverman, Michal Hershfinkel, Teresa Caporale, Stefano L Sensi, Julia Parnis, Christiane Nolte, Daniel Fishman, Varda Shoshan-Barmatz, Sharon Herrmann,[...]. Proc Natl Acad Sci U S A 2010
10
Mitochondria dysfunction in the pathogenesis of Alzheimer's disease: recent advances.
Wenzhang Wang, Fanpeng Zhao, Xiaopin Ma, George Perry, Xiongwei Zhu. Mol Neurodegener 2020
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Mitochondrial Ca2+ overload underlies Abeta oligomers neurotoxicity providing an unexpected mechanism of neuroprotection by NSAIDs.
Sara Sanz-Blasco, Ruth A Valero, Ignacio Rodríguez-Crespo, Carlos Villalobos, Lucía Núñez. PLoS One 2008
Sara Sanz-Blasco, Ruth A Valero, Ignacio Rodríguez-Crespo, Carlos Villalobos, Lucía Núñez. PLoS One 2008
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Oxidative stress and mitochondrial dysfunction in Alzheimer's disease.
Xinglong Wang, Wenzhang Wang, Li Li, George Perry, Hyoung-gon Lee, Xiongwei Zhu. Biochim Biophys Acta 2014
Xinglong Wang, Wenzhang Wang, Li Li, George Perry, Hyoung-gon Lee, Xiongwei Zhu. Biochim Biophys Acta 2014
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Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brain.
Katherine J Kopeikina, George A Carlson, Rose Pitstick, Adam E Ludvigson, Alan Peters, Jennifer I Luebke, Robert M Koffie, Matthew P Frosch, Bradley T Hyman, Tara L Spires-Jones. Am J Pathol 2011
Katherine J Kopeikina, George A Carlson, Rose Pitstick, Adam E Ludvigson, Alan Peters, Jennifer I Luebke, Robert M Koffie, Matthew P Frosch, Bradley T Hyman, Tara L Spires-Jones. Am J Pathol 2011
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The Mitochondrial Permeability Transition Pore: Channel Formation by F-ATP Synthase, Integration in Signal Transduction, and Role in Pathophysiology.
Paolo Bernardi, Andrea Rasola, Michael Forte, Giovanna Lippe. Physiol Rev 2015
Paolo Bernardi, Andrea Rasola, Michael Forte, Giovanna Lippe. Physiol Rev 2015
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Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter.
Joshua M Baughman, Fabiana Perocchi, Hany S Girgis, Molly Plovanich, Casey A Belcher-Timme, Yasemin Sancak, X Robert Bao, Laura Strittmatter, Olga Goldberger, Roman L Bogorad,[...]. Nature 2011
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9
Cyclophilin D modulates mitochondrial F0F1-ATP synthase by interacting with the lateral stalk of the complex.
Valentina Giorgio, Elena Bisetto, Maria Eugenia Soriano, Federica Dabbeni-Sala, Emy Basso, Valeria Petronilli, Michael A Forte, Paolo Bernardi, Giovanna Lippe. J Biol Chem 2009
Valentina Giorgio, Elena Bisetto, Maria Eugenia Soriano, Federica Dabbeni-Sala, Emy Basso, Valeria Petronilli, Michael A Forte, Paolo Bernardi, Giovanna Lippe. J Biol Chem 2009
9
Mitochondrial permeability transition pore in Alzheimer's disease: cyclophilin D and amyloid beta.
Heng Du, Shirley ShiDu Yan. Biochim Biophys Acta 2010
Heng Du, Shirley ShiDu Yan. Biochim Biophys Acta 2010
9
Parkin-mediated mitophagy in mutant hAPP neurons and Alzheimer's disease patient brains.
Xuan Ye, Xiaqin Sun, Valentin Starovoytov, Qian Cai. Hum Mol Genet 2015
Xuan Ye, Xiaqin Sun, Valentin Starovoytov, Qian Cai. Hum Mol Genet 2015
9
Mitochondrial permeability transition pore contributes to mitochondrial dysfunction in fibroblasts of patients with sporadic Alzheimer's disease.
María José Pérez, Daniela P Ponce, Alejandra Aranguiz, Maria I Behrens, Rodrigo A Quintanilla. Redox Biol 2018
María José Pérez, Daniela P Ponce, Alejandra Aranguiz, Maria I Behrens, Rodrigo A Quintanilla. Redox Biol 2018
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Persistence of the mitochondrial permeability transition in the absence of subunit c of human ATP synthase.
Jiuya He, Holly C Ford, Joe Carroll, Shujing Ding, Ian M Fearnley, John E Walker. Proc Natl Acad Sci U S A 2017
Jiuya He, Holly C Ford, Joe Carroll, Shujing Ding, Ian M Fearnley, John E Walker. Proc Natl Acad Sci U S A 2017
9
The Ca2+-induced membrane transition in mitochondria. II. Nature of the Ca2+ trigger site.
R A Haworth, D R Hunter. Arch Biochem Biophys 1979
R A Haworth, D R Hunter. Arch Biochem Biophys 1979
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.