Michael T Alkire, Anthony G Hudetz, Giulio Tononi. Science 2008
Times Cited: 680
Times Cited: 680
Times Cited
Times Co-cited
Similarity
General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal.
Nicholas P Franks. Nat Rev Neurosci 2008
Nicholas P Franks. Nat Rev Neurosci 2008
29
General anesthesia, sleep, and coma.
Emery N Brown, Ralph Lydic, Nicholas D Schiff. N Engl J Med 2010
Emery N Brown, Ralph Lydic, Nicholas D Schiff. N Engl J Med 2010
17
General anesthesia and altered states of arousal: a systems neuroscience analysis.
Emery N Brown, Patrick L Purdon, Christa J Van Dort. Annu Rev Neurosci 2011
Emery N Brown, Patrick L Purdon, Christa J Van Dort. Annu Rev Neurosci 2011
15
Electroencephalogram signatures of loss and recovery of consciousness from propofol.
Patrick L Purdon, Eric T Pierce, Eran A Mukamel, Michael J Prerau, John L Walsh, Kin Foon K Wong, Andres F Salazar-Gomez, Priscilla G Harrell, Aaron L Sampson, Aylin Cimenser,[...]. Proc Natl Acad Sci U S A 2013
Patrick L Purdon, Eric T Pierce, Eran A Mukamel, Michael J Prerau, John L Walsh, Kin Foon K Wong, Andres F Salazar-Gomez, Priscilla G Harrell, Aaron L Sampson, Aylin Cimenser,[...]. Proc Natl Acad Sci U S A 2013
14
Neural correlates of consciousness: progress and problems.
Christof Koch, Marcello Massimini, Melanie Boly, Giulio Tononi. Nat Rev Neurosci 2016
Christof Koch, Marcello Massimini, Melanie Boly, Giulio Tononi. Nat Rev Neurosci 2016
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Breakdown of within- and between-network resting state functional magnetic resonance imaging connectivity during propofol-induced loss of consciousness.
Pierre Boveroux, Audrey Vanhaudenhuyse, Marie-Aurélie Bruno, Quentin Noirhomme, Séverine Lauwick, André Luxen, Christian Degueldre, Alain Plenevaux, Caroline Schnakers, Christophe Phillips,[...]. Anesthesiology 2010
Pierre Boveroux, Audrey Vanhaudenhuyse, Marie-Aurélie Bruno, Quentin Noirhomme, Séverine Lauwick, André Luxen, Christian Degueldre, Alain Plenevaux, Caroline Schnakers, Christophe Phillips,[...]. Anesthesiology 2010
14
A theoretically based index of consciousness independent of sensory processing and behavior.
Adenauer G Casali, Olivia Gosseries, Mario Rosanova, Mélanie Boly, Simone Sarasso, Karina R Casali, Silvia Casarotto, Marie-Aurélie Bruno, Steven Laureys, Giulio Tononi,[...]. Sci Transl Med 2013
Adenauer G Casali, Olivia Gosseries, Mario Rosanova, Mélanie Boly, Simone Sarasso, Karina R Casali, Silvia Casarotto, Marie-Aurélie Bruno, Steven Laureys, Giulio Tononi,[...]. Sci Transl Med 2013
14
Integrated information theory: from consciousness to its physical substrate.
Giulio Tononi, Melanie Boly, Marcello Massimini, Christof Koch. Nat Rev Neurosci 2016
Giulio Tononi, Melanie Boly, Marcello Massimini, Christof Koch. Nat Rev Neurosci 2016
14
Molecular and neuronal substrates for general anaesthetics.
Uwe Rudolph, Bernd Antkowiak. Nat Rev Neurosci 2004
Uwe Rudolph, Bernd Antkowiak. Nat Rev Neurosci 2004
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Conscious Processing and the Global Neuronal Workspace Hypothesis.
George A Mashour, Pieter Roelfsema, Jean-Pierre Changeux, Stanislas Dehaene. Neuron 2020
George A Mashour, Pieter Roelfsema, Jean-Pierre Changeux, Stanislas Dehaene. Neuron 2020
13
Differential Role of Prefrontal and Parietal Cortices in Controlling Level of Consciousness.
Dinesh Pal, Jon G Dean, Tiecheng Liu, Duan Li, Christopher J Watson, Anthony G Hudetz, George A Mashour. Curr Biol 2018
Dinesh Pal, Jon G Dean, Tiecheng Liu, Duan Li, Christopher J Watson, Anthony G Hudetz, George A Mashour. Curr Biol 2018
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Clinical Electroencephalography for Anesthesiologists: Part I: Background and Basic Signatures.
Patrick L Purdon, Aaron Sampson, Kara J Pavone, Emery N Brown. Anesthesiology 2015
Patrick L Purdon, Aaron Sampson, Kara J Pavone, Emery N Brown. Anesthesiology 2015
11
Signature of consciousness in the dynamics of resting-state brain activity.
Pablo Barttfeld, Lynn Uhrig, Jacobo D Sitt, Mariano Sigman, Béchir Jarraya, Stanislas Dehaene. Proc Natl Acad Sci U S A 2015
Pablo Barttfeld, Lynn Uhrig, Jacobo D Sitt, Mariano Sigman, Béchir Jarraya, Stanislas Dehaene. Proc Natl Acad Sci U S A 2015
11
Thalamus Modulates Consciousness via Layer-Specific Control of Cortex.
Michelle J Redinbaugh, Jessica M Phillips, Niranjan A Kambi, Sounak Mohanta, Samantha Andryk, Gaven L Dooley, Mohsen Afrasiabi, Aeyal Raz, Yuri B Saalmann. Neuron 2020
Michelle J Redinbaugh, Jessica M Phillips, Niranjan A Kambi, Sounak Mohanta, Samantha Andryk, Gaven L Dooley, Mohsen Afrasiabi, Aeyal Raz, Yuri B Saalmann. Neuron 2020
12
Bottom-Up and Top-Down Mechanisms of General Anesthetics Modulate Different Dimensions of Consciousness.
George A Mashour, Anthony G Hudetz. Front Neural Circuits 2017
George A Mashour, Anthony G Hudetz. Front Neural Circuits 2017
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Neural Correlates of Unconsciousness in Large-Scale Brain Networks.
George A Mashour, Anthony G Hudetz. Trends Neurosci 2018
George A Mashour, Anthony G Hudetz. Trends Neurosci 2018
14
Effects of sevoflurane and propofol on frontal electroencephalogram power and coherence.
Oluwaseun Akeju, M Brandon Westover, Kara J Pavone, Aaron L Sampson, Katharine E Hartnack, Emery N Brown, Patrick L Purdon. Anesthesiology 2014
Oluwaseun Akeju, M Brandon Westover, Kara J Pavone, Aaron L Sampson, Katharine E Hartnack, Emery N Brown, Patrick L Purdon. Anesthesiology 2014
10
Experimental and theoretical approaches to conscious processing.
Stanislas Dehaene, Jean-Pierre Changeux. Neuron 2011
Stanislas Dehaene, Jean-Pierre Changeux. Neuron 2011
10
Towards a Comprehensive Understanding of Anesthetic Mechanisms of Action: A Decade of Discovery.
Hugh C Hemmings, Paul M Riegelhaupt, Max B Kelz, Ken Solt, Roderic G Eckenhoff, Beverley A Orser, Peter A Goldstein. Trends Pharmacol Sci 2019
Hugh C Hemmings, Paul M Riegelhaupt, Max B Kelz, Ken Solt, Roderic G Eckenhoff, Beverley A Orser, Peter A Goldstein. Trends Pharmacol Sci 2019
12
Thalamic microinjection of nicotine reverses sevoflurane-induced loss of righting reflex in the rat.
Michael T Alkire, Jayme R McReynolds, Emily L Hahn, Akash N Trivedi. Anesthesiology 2007
Michael T Alkire, Jayme R McReynolds, Emily L Hahn, Akash N Trivedi. Anesthesiology 2007
9
Unresponsiveness ≠ unconsciousness.
Robert D Sanders, Giulio Tononi, Steven Laureys, Jamie W Sleigh. Anesthesiology 2012
Robert D Sanders, Giulio Tononi, Steven Laureys, Jamie W Sleigh. Anesthesiology 2012
9
Consciousness and Complexity during Unresponsiveness Induced by Propofol, Xenon, and Ketamine.
Simone Sarasso, Melanie Boly, Martino Napolitani, Olivia Gosseries, Vanessa Charland-Verville, Silvia Casarotto, Mario Rosanova, Adenauer Girardi Casali, Jean-Francois Brichant, Pierre Boveroux,[...]. Curr Biol 2015
Simone Sarasso, Melanie Boly, Martino Napolitani, Olivia Gosseries, Vanessa Charland-Verville, Silvia Casarotto, Mario Rosanova, Adenauer Girardi Casali, Jean-Francois Brichant, Pierre Boveroux,[...]. Curr Biol 2015
9
Disruption of frontal-parietal communication by ketamine, propofol, and sevoflurane.
UnCheol Lee, SeungWoo Ku, GyuJeong Noh, SeungHye Baek, ByungMoon Choi, George A Mashour. Anesthesiology 2013
UnCheol Lee, SeungWoo Ku, GyuJeong Noh, SeungHye Baek, ByungMoon Choi, George A Mashour. Anesthesiology 2013
9
General Anesthesia Decouples Cortical Pyramidal Neurons.
Mototaka Suzuki, Matthew E Larkum. Cell 2020
Mototaka Suzuki, Matthew E Larkum. Cell 2020
12
Breakdown of cortical effective connectivity during sleep.
Marcello Massimini, Fabio Ferrarelli, Reto Huber, Steve K Esser, Harpreet Singh, Giulio Tononi. Science 2005
Marcello Massimini, Fabio Ferrarelli, Reto Huber, Steve K Esser, Harpreet Singh, Giulio Tononi. Science 2005
8
Complexity of Multi-Dimensional Spontaneous EEG Decreases during Propofol Induced General Anaesthesia.
Michael Schartner, Anil Seth, Quentin Noirhomme, Melanie Boly, Marie-Aurelie Bruno, Steven Laureys, Adam Barrett. PLoS One 2015
Michael Schartner, Anil Seth, Quentin Noirhomme, Melanie Boly, Marie-Aurelie Bruno, Steven Laureys, Adam Barrett. PLoS One 2015
8
Breakdown in cortical effective connectivity during midazolam-induced loss of consciousness.
Fabio Ferrarelli, Marcello Massimini, Simone Sarasso, Adenauer Casali, Brady A Riedner, Giuditta Angelini, Giulio Tononi, Robert A Pearce. Proc Natl Acad Sci U S A 2010
Fabio Ferrarelli, Marcello Massimini, Simone Sarasso, Adenauer Casali, Brady A Riedner, Giuditta Angelini, Giulio Tononi, Robert A Pearce. Proc Natl Acad Sci U S A 2010
8
Thalamocortical model for a propofol-induced alpha-rhythm associated with loss of consciousness.
Shinung Ching, Aylin Cimenser, Patrick L Purdon, Emery N Brown, Nancy J Kopell. Proc Natl Acad Sci U S A 2010
Shinung Ching, Aylin Cimenser, Patrick L Purdon, Emery N Brown, Nancy J Kopell. Proc Natl Acad Sci U S A 2010
8
The alpha2-adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effects.
Laura E Nelson, Jun Lu, Tianzhi Guo, Clifford B Saper, Nicholas P Franks, Mervyn Maze. Anesthesiology 2003
Laura E Nelson, Jun Lu, Tianzhi Guo, Clifford B Saper, Nicholas P Franks, Mervyn Maze. Anesthesiology 2003
7
Disruption of thalamic functional connectivity is a neural correlate of dexmedetomidine-induced unconsciousness.
Oluwaseun Akeju, Marco L Loggia, Ciprian Catana, Kara J Pavone, Rafael Vazquez, James Rhee, Violeta Contreras Ramirez, Daniel B Chonde, David Izquierdo-Garcia, Grae Arabasz,[...]. Elife 2014
Oluwaseun Akeju, Marco L Loggia, Ciprian Catana, Kara J Pavone, Rafael Vazquez, James Rhee, Violeta Contreras Ramirez, Daniel B Chonde, David Izquierdo-Garcia, Grae Arabasz,[...]. Elife 2014
8
The sedative component of anesthesia is mediated by GABA(A) receptors in an endogenous sleep pathway.
L E Nelson, T Z Guo, J Lu, C B Saper, N P Franks, M Maze. Nat Neurosci 2002
L E Nelson, T Z Guo, J Lu, C B Saper, N P Franks, M Maze. Nat Neurosci 2002
7
Electrical stimulation of the ventral tegmental area induces reanimation from general anesthesia.
Ken Solt, Christa J Van Dort, Jessica J Chemali, Norman E Taylor, Jonathan D Kenny, Emery N Brown. Anesthesiology 2014
Ken Solt, Christa J Van Dort, Jessica J Chemali, Norman E Taylor, Jonathan D Kenny, Emery N Brown. Anesthesiology 2014
8
Human consciousness is supported by dynamic complex patterns of brain signal coordination.
A Demertzi, E Tagliazucchi, S Dehaene, G Deco, P Barttfeld, F Raimondo, C Martial, D Fernández-Espejo, B Rohaut, H U Voss,[...]. Sci Adv 2019
A Demertzi, E Tagliazucchi, S Dehaene, G Deco, P Barttfeld, F Raimondo, C Martial, D Fernández-Espejo, B Rohaut, H U Voss,[...]. Sci Adv 2019
7
Regional slow waves and spindles in human sleep.
Yuval Nir, Richard J Staba, Thomas Andrillon, Vladyslav V Vyazovskiy, Chiara Cirelli, Itzhak Fried, Giulio Tononi. Neuron 2011
Yuval Nir, Richard J Staba, Thomas Andrillon, Vladyslav V Vyazovskiy, Chiara Cirelli, Itzhak Fried, Giulio Tononi. Neuron 2011
7
Local sleep in awake rats.
Vladyslav V Vyazovskiy, Umberto Olcese, Erin C Hanlon, Yuval Nir, Chiara Cirelli, Giulio Tononi. Nature 2011
Vladyslav V Vyazovskiy, Umberto Olcese, Erin C Hanlon, Yuval Nir, Chiara Cirelli, Giulio Tononi. Nature 2011
7
Are the Neural Correlates of Consciousness in the Front or in the Back of the Cerebral Cortex? Clinical and Neuroimaging Evidence.
Melanie Boly, Marcello Massimini, Naotsugu Tsuchiya, Bradley R Postle, Christof Koch, Giulio Tononi. J Neurosci 2017
Melanie Boly, Marcello Massimini, Naotsugu Tsuchiya, Bradley R Postle, Christof Koch, Giulio Tononi. J Neurosci 2017
7
Studies on the mechanism of general anesthesia.
Mahmud Arif Pavel, E Nicholas Petersen, Hao Wang, Richard A Lerner, Scott B Hansen. Proc Natl Acad Sci U S A 2020
Mahmud Arif Pavel, E Nicholas Petersen, Hao Wang, Richard A Lerner, Scott B Hansen. Proc Natl Acad Sci U S A 2020
10
Rapid fragmentation of neuronal networks at the onset of propofol-induced unconsciousness.
Laura D Lewis, Veronica S Weiner, Eran A Mukamel, Jacob A Donoghue, Emad N Eskandar, Joseph R Madsen, William S Anderson, Leigh R Hochberg, Sydney S Cash, Emery N Brown,[...]. Proc Natl Acad Sci U S A 2012
Laura D Lewis, Veronica S Weiner, Eran A Mukamel, Jacob A Donoghue, Emad N Eskandar, Joseph R Madsen, William S Anderson, Leigh R Hochberg, Sydney S Cash, Emery N Brown,[...]. Proc Natl Acad Sci U S A 2012
7
Propofol anesthesia and sleep: a high-density EEG study.
Michael Murphy, Marie-Aurélie Bruno, Brady A Riedner, Pierre Boveroux, Quentin Noirhomme, Eric C Landsness, Jean-Francois Brichant, Christophe Phillips, Marcello Massimini, Steven Laureys,[...]. Sleep 2011
Michael Murphy, Marie-Aurélie Bruno, Brady A Riedner, Pierre Boveroux, Quentin Noirhomme, Eric C Landsness, Jean-Francois Brichant, Christophe Phillips, Marcello Massimini, Steven Laureys,[...]. Sleep 2011
7
Sleep state switching.
Clifford B Saper, Patrick M Fuller, Nigel P Pedersen, Jun Lu, Thomas E Scammell. Neuron 2010
Clifford B Saper, Patrick M Fuller, Nigel P Pedersen, Jun Lu, Thomas E Scammell. Neuron 2010
7
A Common Neuroendocrine Substrate for Diverse General Anesthetics and Sleep.
Li-Feng Jiang-Xie, Luping Yin, Shengli Zhao, Vincent Prevosto, Bao-Xia Han, Kafui Dzirasa, Fan Wang. Neuron 2019
Li-Feng Jiang-Xie, Luping Yin, Shengli Zhao, Vincent Prevosto, Bao-Xia Han, Kafui Dzirasa, Fan Wang. Neuron 2019
13
Disruption of corticocortical information transfer during ketamine anesthesia in the primate brain.
Karen E Schroeder, Zachary T Irwin, Matt Gaidica, J Nicole Bentley, Parag G Patil, George A Mashour, Cynthia A Chestek. Neuroimage 2016
Karen E Schroeder, Zachary T Irwin, Matt Gaidica, J Nicole Bentley, Parag G Patil, George A Mashour, Cynthia A Chestek. Neuroimage 2016
14
From the phenomenology to the mechanisms of consciousness: Integrated Information Theory 3.0.
Masafumi Oizumi, Larissa Albantakis, Giulio Tononi. PLoS Comput Biol 2014
Masafumi Oizumi, Larissa Albantakis, Giulio Tononi. PLoS Comput Biol 2014
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Slow-wave activity saturation and thalamocortical isolation during propofol anesthesia in humans.
Róisín Ní Mhuircheartaigh, Catherine Warnaby, Richard Rogers, Saad Jbabdi, Irene Tracey. Sci Transl Med 2013
Róisín Ní Mhuircheartaigh, Catherine Warnaby, Richard Rogers, Saad Jbabdi, Irene Tracey. Sci Transl Med 2013
6
Top-down mechanisms of anesthetic-induced unconsciousness.
George A Mashour. Front Syst Neurosci 2014
George A Mashour. Front Syst Neurosci 2014
8
Brain areas that influence general anesthesia.
L Stan Leung, Tao Luo, Jingyi Ma, Ian Herrick. Prog Neurobiol 2014
L Stan Leung, Tao Luo, Jingyi Ma, Ian Herrick. Prog Neurobiol 2014
9
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