Robert A Schnoll, Freda Patterson, E Paul Wileyto, Rachel F Tyndale, Neal Benowitz, Caryn Lerman. Pharmacol Biochem Behav 2009
Times Cited: 156
Times Cited: 156
Times Cited
Times Co-cited
Similarity
Use of the nicotine metabolite ratio as a genetically informed biomarker of response to nicotine patch or varenicline for smoking cessation: a randomised, double-blind placebo-controlled trial.
Caryn Lerman, Robert A Schnoll, Larry W Hawk, Paul Cinciripini, Tony P George, E Paul Wileyto, Gary E Swan, Neal L Benowitz, Daniel F Heitjan, Rachel F Tyndale. Lancet Respir Med 2015
Caryn Lerman, Robert A Schnoll, Larry W Hawk, Paul Cinciripini, Tony P George, E Paul Wileyto, Gary E Swan, Neal L Benowitz, Daniel F Heitjan, Rachel F Tyndale. Lancet Respir Med 2015
60
Nicotine metabolite ratio predicts efficacy of transdermal nicotine for smoking cessation.
Caryn Lerman, Rachel Tyndale, Freda Patterson, E Paul Wileyto, Peter G Shields, Angela Pinto, Neal Benowitz. Clin Pharmacol Ther 2006
Caryn Lerman, Rachel Tyndale, Freda Patterson, E Paul Wileyto, Peter G Shields, Angela Pinto, Neal Benowitz. Clin Pharmacol Ther 2006
54
Nicotine metabolite ratio as an index of cytochrome P450 2A6 metabolic activity.
Delia Dempsey, Piotr Tutka, Peyton Jacob, Faith Allen, Kerri Schoedel, Rachel F Tyndale, Neal L Benowitz. Clin Pharmacol Ther 2004
Delia Dempsey, Piotr Tutka, Peyton Jacob, Faith Allen, Kerri Schoedel, Rachel F Tyndale, Neal L Benowitz. Clin Pharmacol Ther 2004
53
Toward personalized therapy for smoking cessation: a randomized placebo-controlled trial of bupropion.
F Patterson, R A Schnoll, E P Wileyto, A Pinto, L H Epstein, P G Shields, L W Hawk, R F Tyndale, N Benowitz, C Lerman. Clin Pharmacol Ther 2008
F Patterson, R A Schnoll, E P Wileyto, A Pinto, L H Epstein, P G Shields, L W Hawk, R F Tyndale, N Benowitz, C Lerman. Clin Pharmacol Ther 2008
48
Association of nicotine metabolite ratio and CYP2A6 genotype with smoking cessation treatment in African-American light smokers.
M K Ho, J C Mwenifumbo, N Al Koudsi, K S Okuyemi, J S Ahluwalia, N L Benowitz, R F Tyndale. Clin Pharmacol Ther 2009
M K Ho, J C Mwenifumbo, N Al Koudsi, K S Okuyemi, J S Ahluwalia, N L Benowitz, R F Tyndale. Clin Pharmacol Ther 2009
39
Known and novel sources of variability in the nicotine metabolite ratio in a large sample of treatment-seeking smokers.
Meghan J Chenoweth, Maria Novalen, Larry W Hawk, Robert A Schnoll, Tony P George, Paul M Cinciripini, Caryn Lerman, Rachel F Tyndale. Cancer Epidemiol Biomarkers Prev 2014
Meghan J Chenoweth, Maria Novalen, Larry W Hawk, Robert A Schnoll, Tony P George, Paul M Cinciripini, Caryn Lerman, Rachel F Tyndale. Cancer Epidemiol Biomarkers Prev 2014
52
Reproducibility of the nicotine metabolite ratio in cigarette smokers.
Gideon St Helen, Maria Novalen, Daniel F Heitjan, Delia Dempsey, Peyton Jacob, Adel Aziziyeh, Victoria C Wing, Tony P George, Rachel F Tyndale, Neal L Benowitz. Cancer Epidemiol Biomarkers Prev 2012
Gideon St Helen, Maria Novalen, Daniel F Heitjan, Delia Dempsey, Peyton Jacob, Adel Aziziyeh, Victoria C Wing, Tony P George, Rachel F Tyndale, Neal L Benowitz. Cancer Epidemiol Biomarkers Prev 2012
42
Rapid nicotine clearance is associated with greater reward and heart rate increases from intravenous nicotine.
Mehmet Sofuoglu, Aryeh I Herman, Haleh Nadim, Peter Jatlow. Neuropsychopharmacology 2012
Mehmet Sofuoglu, Aryeh I Herman, Haleh Nadim, Peter Jatlow. Neuropsychopharmacology 2012
32
Genetic variation in nicotine metabolism predicts the efficacy of extended-duration transdermal nicotine therapy.
C Lerman, C Jepson, E P Wileyto, F Patterson, R Schnoll, M Mroziewicz, N Benowitz, R F Tyndale. Clin Pharmacol Ther 2010
C Lerman, C Jepson, E P Wileyto, F Patterson, R Schnoll, M Mroziewicz, N Benowitz, R F Tyndale. Clin Pharmacol Ther 2010
34
Nicotine chemistry, metabolism, kinetics and biomarkers.
Neal L Benowitz, Janne Hukkanen, Peyton Jacob. Handb Exp Pharmacol 2009
Neal L Benowitz, Janne Hukkanen, Peyton Jacob. Handb Exp Pharmacol 2009
27
Nicotine metabolite ratio (3-hydroxycotinine/cotinine) in plasma and urine by different analytical methods and laboratories: implications for clinical implementation.
Julie-Anne Tanner, Maria Novalen, Peter Jatlow, Marilyn A Huestis, Sharon E Murphy, Jaakko Kaprio, Aino Kankaanpää, Laurence Galanti, Cristiana Stefan, Tony P George,[...]. Cancer Epidemiol Biomarkers Prev 2015
Julie-Anne Tanner, Maria Novalen, Peter Jatlow, Marilyn A Huestis, Sharon E Murphy, Jaakko Kaprio, Aino Kankaanpää, Laurence Galanti, Cristiana Stefan, Tony P George,[...]. Cancer Epidemiol Biomarkers Prev 2015
50
The Fagerström Test for Nicotine Dependence: a revision of the Fagerström Tolerance Questionnaire.
T F Heatherton, L T Kozlowski, R C Frecker, K O Fagerström. Br J Addict 1991
T F Heatherton, L T Kozlowski, R C Frecker, K O Fagerström. Br J Addict 1991
25
Nicotine metabolite ratio as a predictor of cigarette consumption.
Neal L Benowitz, Ovide F Pomerleau, Cynthia S Pomerleau, Peyton Jacob. Nicotine Tob Res 2003
Neal L Benowitz, Ovide F Pomerleau, Cynthia S Pomerleau, Peyton Jacob. Nicotine Tob Res 2003
25
Pharmacotherapy effects on smoking cessation vary with nicotine metabolism gene (CYP2A6).
Li-Shiun Chen, A Joseph Bloom, Timothy B Baker, Stevens S Smith, Megan E Piper, Maribel Martinez, Nancy Saccone, Dorothy Hatsukami, Alison Goate, Laura Bierut. Addiction 2014
Li-Shiun Chen, A Joseph Bloom, Timothy B Baker, Stevens S Smith, Megan E Piper, Maribel Martinez, Nancy Saccone, Dorothy Hatsukami, Alison Goate, Laura Bierut. Addiction 2014
40
Female sex and oral contraceptive use accelerate nicotine metabolism.
Neal L Benowitz, Christina N Lessov-Schlaggar, Gary E Swan, Peyton Jacob. Clin Pharmacol Ther 2006
Neal L Benowitz, Christina N Lessov-Schlaggar, Gary E Swan, Peyton Jacob. Clin Pharmacol Ther 2006
24
Nicotine metabolite ratio predicts smoking topography and carcinogen biomarker level.
Andrew A Strasser, Neal L Benowitz, Angela G Pinto, Kathy Z Tang, Stephen S Hecht, Steve G Carmella, Rachel F Tyndale, Caryn E Lerman. Cancer Epidemiol Biomarkers Prev 2011
Andrew A Strasser, Neal L Benowitz, Angela G Pinto, Kathy Z Tang, Stephen S Hecht, Steve G Carmella, Rachel F Tyndale, Caryn E Lerman. Cancer Epidemiol Biomarkers Prev 2011
26
Characterization of CYP2A6 involved in 3'-hydroxylation of cotinine in human liver microsomes.
M Nakajima, T Yamamoto, K Nunoya, T Yokoi, K Nagashima, K Inoue, Y Funae, N Shimada, T Kamataki, Y Kuroiwa. J Pharmacol Exp Ther 1996
M Nakajima, T Yamamoto, K Nunoya, T Yokoi, K Nagashima, K Inoue, Y Funae, N Shimada, T Kamataki, Y Kuroiwa. J Pharmacol Exp Ther 1996
23
Stability of the nicotine metabolite ratio in ad libitum and reducing smokers.
Marc E Mooney, Zhong-Ze Li, Sharon E Murphy, Paul R Pentel, Chap Le, Dorothy K Hatsukami. Cancer Epidemiol Biomarkers Prev 2008
Marc E Mooney, Zhong-Ze Li, Sharon E Murphy, Paul R Pentel, Chap Le, Dorothy K Hatsukami. Cancer Epidemiol Biomarkers Prev 2008
57
A Genome-Wide Association Study of a Biomarker of Nicotine Metabolism.
Anu Loukola, Jadwiga Buchwald, Richa Gupta, Teemu Palviainen, Jenni Hällfors, Emmi Tikkanen, Tellervo Korhonen, Miina Ollikainen, Antti-Pekka Sarin, Samuli Ripatti,[...]. PLoS Genet 2015
Anu Loukola, Jadwiga Buchwald, Richa Gupta, Teemu Palviainen, Jenni Hällfors, Emmi Tikkanen, Tellervo Korhonen, Miina Ollikainen, Antti-Pekka Sarin, Samuli Ripatti,[...]. PLoS Genet 2015
31
Within-subject variation of the salivary 3HC/COT ratio in regular daily smokers: prospects for estimating CYP2A6 enzyme activity in large-scale surveys of nicotine metabolic rate.
Rod A Lea, Stuart Dickson, Neal L Benowitz. J Anal Toxicol 2006
Rod A Lea, Stuart Dickson, Neal L Benowitz. J Anal Toxicol 2006
38
Metabolism and disposition kinetics of nicotine.
Janne Hukkanen, Peyton Jacob, Neal L Benowitz. Pharmacol Rev 2005
Janne Hukkanen, Peyton Jacob, Neal L Benowitz. Pharmacol Rev 2005
21
Relationship between CYP2A6 and CHRNA5-CHRNA3-CHRNB4 variation and smoking behaviors and lung cancer risk.
Catherine A Wassenaar, Qiong Dong, Qingyi Wei, Christopher I Amos, Margaret R Spitz, Rachel F Tyndale. J Natl Cancer Inst 2011
Catherine A Wassenaar, Qiong Dong, Qingyi Wei, Christopher I Amos, Margaret R Spitz, Rachel F Tyndale. J Natl Cancer Inst 2011
21
A major role for CYP2A6 in nicotine C-oxidation by human liver microsomes.
E S Messina, R F Tyndale, E M Sellers. J Pharmacol Exp Ther 1997
E S Messina, R F Tyndale, E M Sellers. J Pharmacol Exp Ther 1997
20
Ethnic variation in CYP2A6 and association of genetically slow nicotine metabolism and smoking in adult Caucasians.
Kerri A Schoedel, Ewa B Hoffmann, Yushu Rao, Edward M Sellers, Rachel F Tyndale. Pharmacogenetics 2004
Kerri A Schoedel, Ewa B Hoffmann, Yushu Rao, Edward M Sellers, Rachel F Tyndale. Pharmacogenetics 2004
20
Genetic and environmental influences on the ratio of 3'hydroxycotinine to cotinine in plasma and urine.
Gary E Swan, Christina N Lessov-Schlaggar, Andrew W Bergen, Yungang He, Rachel F Tyndale, Neal L Benowitz. Pharmacogenet Genomics 2009
Gary E Swan, Christina N Lessov-Schlaggar, Andrew W Bergen, Yungang He, Rachel F Tyndale, Neal L Benowitz. Pharmacogenet Genomics 2009
29
Genetic variation in CYP2A6 predicts neural reactivity to smoking cues as measured using fMRI.
Deborah W Tang, Brian Hello, Margaret Mroziewicz, Lesley K Fellows, Rachel F Tyndale, Alain Dagher. Neuroimage 2012
Deborah W Tang, Brian Hello, Margaret Mroziewicz, Lesley K Fellows, Rachel F Tyndale, Alain Dagher. Neuroimage 2012
43
The relationship between the nicotine metabolite ratio and three self-report measures of nicotine dependence across sex and race.
Robert A Schnoll, Tony P George, Larry Hawk, Paul Cinciripini, Paul Wileyto, Rachel F Tyndale. Psychopharmacology (Berl) 2014
Robert A Schnoll, Tony P George, Larry Hawk, Paul Cinciripini, Paul Wileyto, Rachel F Tyndale. Psychopharmacology (Berl) 2014
39
Rate of nicotine metabolism and smoking cessation outcomes in a community-based sample of treatment-seeking smokers.
Amanda Kaufmann, Brian Hitsman, Patricia M Goelz, Anna Veluz-Wilkins, Sonja Blazekovic, Lindsay Powers, Frank T Leone, Peter Gariti, Rachel F Tyndale, Robert A Schnoll. Addict Behav 2015
Amanda Kaufmann, Brian Hitsman, Patricia M Goelz, Anna Veluz-Wilkins, Sonja Blazekovic, Lindsay Powers, Frank T Leone, Peter Gariti, Rachel F Tyndale, Robert A Schnoll. Addict Behav 2015
58
Determinants of the rate of nicotine metabolism and effects on smoking behavior.
Elaine Johnstone, Neal Benowitz, Anna Cargill, Robyn Jacob, Lesley Hinks, Ian Day, Mike Murphy, Robert Walton. Clin Pharmacol Ther 2006
Elaine Johnstone, Neal Benowitz, Anna Cargill, Robyn Jacob, Lesley Hinks, Ian Day, Mike Murphy, Robert Walton. Clin Pharmacol Ther 2006
16
CYP2A6 slow nicotine metabolism is associated with increased quitting by adolescent smokers.
Meghan J Chenoweth, Jennifer O'Loughlin, Marie-Pierre Sylvestre, Rachel F Tyndale. Pharmacogenet Genomics 2013
Meghan J Chenoweth, Jennifer O'Loughlin, Marie-Pierre Sylvestre, Rachel F Tyndale. Pharmacogenet Genomics 2013
34
CYP2A6 genotype and the metabolism and disposition kinetics of nicotine.
Neal L Benowitz, Gary E Swan, Peyton Jacob, Christina N Lessov-Schlaggar, Rachel F Tyndale. Clin Pharmacol Ther 2006
Neal L Benowitz, Gary E Swan, Peyton Jacob, Christina N Lessov-Schlaggar, Rachel F Tyndale. Clin Pharmacol Ther 2006
15
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.
Thorgeir E Thorgeirsson, Daniel F Gudbjartsson, Ida Surakka, Jacqueline M Vink, Najaf Amin, Frank Geller, Patrick Sulem, Thorunn Rafnar, Tõnu Esko, Stefan Walter,[...]. Nat Genet 2010
Thorgeir E Thorgeirsson, Daniel F Gudbjartsson, Ida Surakka, Jacqueline M Vink, Najaf Amin, Frank Geller, Patrick Sulem, Thorunn Rafnar, Tõnu Esko, Stefan Walter,[...]. Nat Genet 2010
15
Biomarkers for smoking cessation.
K J Bough, C Lerman, J E Rose, F J McClernon, P J Kenny, R F Tyndale, S P David, E A Stein, G R Uhl, D V Conti,[...]. Clin Pharmacol Ther 2013
K J Bough, C Lerman, J E Rose, F J McClernon, P J Kenny, R F Tyndale, S P David, E A Stein, G R Uhl, D V Conti,[...]. Clin Pharmacol Ther 2013
34
15
Interplay of genetic risk factors (CHRNA5-CHRNA3-CHRNB4) and cessation treatments in smoking cessation success.
Li-Shiun Chen, Timothy B Baker, Megan E Piper, Naomi Breslau, Dale S Cannon, Kimberly F Doheny, Stephanie M Gogarten, Eric O Johnson, Nancy L Saccone, Jen C Wang,[...]. Am J Psychiatry 2012
Li-Shiun Chen, Timothy B Baker, Megan E Piper, Naomi Breslau, Dale S Cannon, Kimberly F Doheny, Stephanie M Gogarten, Eric O Johnson, Nancy L Saccone, Jen C Wang,[...]. Am J Psychiatry 2012
15
Precision Medicine for Tobacco Dependence: Development and Validation of the Nicotine Metabolite Ratio.
Cheyenne E Allenby, Kelly A Boylan, Caryn Lerman, Mary Falcone. J Neuroimmune Pharmacol 2016
Cheyenne E Allenby, Kelly A Boylan, Caryn Lerman, Mary Falcone. J Neuroimmune Pharmacol 2016
42
Systematic review of the relationship between the 3-hydroxycotinine/cotinine ratio and cigarette dependence.
Oliver West, Peter Hajek, Hayden McRobbie. Psychopharmacology (Berl) 2011
Oliver West, Peter Hajek, Hayden McRobbie. Psychopharmacology (Berl) 2011
40
Nicotinic acetylcholine receptor variation and response to smoking cessation therapies.
Andrew W Bergen, Harold S Javitz, Ruth Krasnow, Denise Nishita, Martha Michel, David V Conti, Jinghua Liu, Won Lee, Christopher K Edlund, Sharon Hall,[...]. Pharmacogenet Genomics 2013
Andrew W Bergen, Harold S Javitz, Ruth Krasnow, Denise Nishita, Martha Michel, David V Conti, Jinghua Liu, Won Lee, Christopher K Edlund, Sharon Hall,[...]. Pharmacogenet Genomics 2013
23
Meta-analysis and imputation refines the association of 15q25 with smoking quantity.
Jason Z Liu, Federica Tozzi, Dawn M Waterworth, Sreekumar G Pillai, Pierandrea Muglia, Lefkos Middleton, Wade Berrettini, Christopher W Knouff, Xin Yuan, Gérard Waeber,[...]. Nat Genet 2010
Jason Z Liu, Federica Tozzi, Dawn M Waterworth, Sreekumar G Pillai, Pierandrea Muglia, Lefkos Middleton, Wade Berrettini, Christopher W Knouff, Xin Yuan, Gérard Waeber,[...]. Nat Genet 2010
14
Stability of the nicotine metabolite ratio in smokers of progressively reduced nicotine content cigarettes.
Gideon St Helen, Peyton Jacob, Neal L Benowitz. Nicotine Tob Res 2013
Gideon St Helen, Peyton Jacob, Neal L Benowitz. Nicotine Tob Res 2013
60
Role of human cytochrome P4502A6 in C-oxidation of nicotine.
M Nakajima, T Yamamoto, K Nunoya, T Yokoi, K Nagashima, K Inoue, Y Funae, N Shimada, T Kamataki, Y Kuroiwa. Drug Metab Dispos 1996
M Nakajima, T Yamamoto, K Nunoya, T Yokoi, K Nagashima, K Inoue, Y Funae, N Shimada, T Kamataki, Y Kuroiwa. Drug Metab Dispos 1996
14
A variant associated with nicotine dependence, lung cancer and peripheral arterial disease.
Thorgeir E Thorgeirsson, Frank Geller, Patrick Sulem, Thorunn Rafnar, Anna Wiste, Kristinn P Magnusson, Andrei Manolescu, Gudmar Thorleifsson, Hreinn Stefansson, Andres Ingason,[...]. Nature 2008
Thorgeir E Thorgeirsson, Frank Geller, Patrick Sulem, Thorunn Rafnar, Anna Wiste, Kristinn P Magnusson, Andrei Manolescu, Gudmar Thorleifsson, Hreinn Stefansson, Andres Ingason,[...]. Nature 2008
13
Variation in trans-3'-hydroxycotinine glucuronidation does not alter the nicotine metabolite ratio or nicotine intake.
Andy Z X Zhu, Qian Zhou, Lisa Sanderson Cox, Jasjit S Ahluwalia, Neal L Benowitz, Rachel F Tyndale. PLoS One 2013
Andy Z X Zhu, Qian Zhou, Lisa Sanderson Cox, Jasjit S Ahluwalia, Neal L Benowitz, Rachel F Tyndale. PLoS One 2013
40
CYP2A6 and CYP2B6 genetic variation and its association with nicotine metabolism in South Western Alaska Native people.
Matthew J Binnington, Andy Z X Zhu, Caroline C Renner, Anne P Lanier, Dorothy K Hatsukami, Neal L Benowitz, Rachel F Tyndale. Pharmacogenet Genomics 2012
Matthew J Binnington, Andy Z X Zhu, Caroline C Renner, Anne P Lanier, Dorothy K Hatsukami, Neal L Benowitz, Rachel F Tyndale. Pharmacogenet Genomics 2012
38
The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European-Americans.
Joseph Bloom, Anthony L Hinrichs, Jen C Wang, Linda B von Weymarn, Evan D Kharasch, Laura J Bierut, Alison Goate, Sharon E Murphy. Pharmacogenet Genomics 2011
Joseph Bloom, Anthony L Hinrichs, Jen C Wang, Linda B von Weymarn, Evan D Kharasch, Laura J Bierut, Alison Goate, Sharon E Murphy. Pharmacogenet Genomics 2011
19
Determination of the nicotine metabolites cotinine and trans-3'-hydroxycotinine in biologic fluids of smokers and non-smokers using liquid chromatography-tandem mass spectrometry: biomarkers for tobacco smoke exposure and for phenotyping cytochrome P450 2A6 activity.
Peyton Jacob, Lisa Yu, Minjiang Duan, Lita Ramos, Olivia Yturralde, Neal L Benowitz. J Chromatogr B Analyt Technol Biomed Life Sci 2011
Peyton Jacob, Lisa Yu, Minjiang Duan, Lita Ramos, Olivia Yturralde, Neal L Benowitz. J Chromatogr B Analyt Technol Biomed Life Sci 2011
11
Pharmacological interventions for smoking cessation: an overview and network meta-analysis.
Kate Cahill, Sarah Stevens, Rafael Perera, Tim Lancaster. Cochrane Database Syst Rev 2013
Kate Cahill, Sarah Stevens, Rafael Perera, Tim Lancaster. Cochrane Database Syst Rev 2013
11
Outcome criteria in smoking cessation trials: proposal for a common standard.
Robert West, Peter Hajek, Lindsay Stead, John Stapleton. Addiction 2005
Robert West, Peter Hajek, Lindsay Stead, John Stapleton. Addiction 2005
11
Rate of nicotine metabolism and withdrawal symptoms in adolescent light smokers.
Mark L Rubinstein, Neal L Benowitz, Glenna M Auerback, Anna-Barbara Moscicki. Pediatrics 2008
Mark L Rubinstein, Neal L Benowitz, Glenna M Auerback, Anna-Barbara Moscicki. Pediatrics 2008
25
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.