Randell T Libby, Katharine A Hagerman, Victor V Pineda, Rachel Lau, Diane H Cho, Sandy L Baccam, Michelle M Axford, John D Cleary, James M Moore, Bryce L Sopher, Stephen J Tapscott, Galina N Filippova, Christopher E Pearson, Albert R La Spada. PLoS Genet 2008
Times Cited: 100
Times Cited: 100
Times Cited
Times Co-cited
Similarity
Repeat instability: mechanisms of dynamic mutations.
Christopher E Pearson, Kerrie Nichol Edamura, John D Cleary. Nat Rev Genet 2005
Christopher E Pearson, Kerrie Nichol Edamura, John D Cleary. Nat Rev Genet 2005
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CTCF-binding sites flank CTG/CAG repeats and form a methylation-sensitive insulator at the DM1 locus.
G N Filippova, C P Thienes, B H Penn, D H Cho, Y J Hu, J M Moore, T R Klesert, V V Lobanenkov, S J Tapscott. Nat Genet 2001
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30
Antisense transcription and heterochromatin at the DM1 CTG repeats are constrained by CTCF.
Diane H Cho, Cortlandt P Thienes, Sarah E Mahoney, Erwin Analau, Galina N Filippova, Stephen J Tapscott. Mol Cell 2005
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Dnmt1 deficiency promotes CAG repeat expansion in the mouse germline.
Vincent Dion, Yunfu Lin, Leroy Hubert, Robert A Waterland, John H Wilson. Hum Mol Genet 2008
Vincent Dion, Yunfu Lin, Leroy Hubert, Robert A Waterland, John H Wilson. Hum Mol Genet 2008
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Repeat instability as the basis for human diseases and as a potential target for therapy.
Arturo López Castel, John D Cleary, Christopher E Pearson. Nat Rev Mol Cell Biol 2010
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Instability and chromatin structure of expanded trinucleotide repeats.
Vincent Dion, John H Wilson. Trends Genet 2009
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OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells.
Irina V Kovtun, Yuan Liu, Magnar Bjoras, Arne Klungland, Samuel H Wilson, Cynthia T McMurray. Nature 2007
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Genomic context drives SCA7 CAG repeat instability, while expressed SCA7 cDNAs are intergenerationally and somatically stable in transgenic mice.
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Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice.
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18
Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes.
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Mechanisms of trinucleotide repeat instability during human development.
Cynthia T McMurray. Nat Rev Genet 2010
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Tissue- and age-specific DNA replication patterns at the CTG/CAG-expanded human myotonic dystrophy type 1 locus.
John D Cleary, Stéphanie Tomé, Arturo López Castel, Gagan B Panigrahi, Laurent Foiry, Katharine A Hagerman, Hana Sroka, David Chitayat, Geneviève Gourdon, Christopher E Pearson. Nat Struct Mol Biol 2010
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32
CREB-binding protein modulates repeat instability in a Drosophila model for polyQ disease.
Joonil Jung, Nancy Bonini. Science 2007
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17
Transcription-induced CAG repeat contraction in human cells is mediated in part by transcription-coupled nucleotide excision repair.
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17
Evidence of cis-acting factors in replication-mediated trinucleotide repeat instability in primate cells.
John D Cleary, Kerrie Nichol, Yuh-Hwa Wang, Christopher E Pearson. Nat Genet 2002
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16
An antisense transcript spanning the CGG repeat region of FMR1 is upregulated in premutation carriers but silenced in full mutation individuals.
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16
Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome.
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Transcription promotes contraction of CAG repeat tracts in human cells.
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16
Somatic expansion behaviour of the (CTG)n repeat in myotonic dystrophy knock-in mice is differentially affected by Msh3 and Msh6 mismatch-repair proteins.
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15
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15
Pms2 is a genetic enhancer of trinucleotide CAG.CTG repeat somatic mosaicism: implications for the mechanism of triplet repeat expansion.
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15
Bidirectional expression of CUG and CAG expansion transcripts and intranuclear polyglutamine inclusions in spinocerebellar ataxia type 8.
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14
Mismatch repair gene Msh2 modifies the timing of early disease in Hdh(Q111) striatum.
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14
Expanded CTG repeat demarcates a boundary for abnormal CpG methylation in myotonic dystrophy patient tissues.
Arturo López Castel, Masayuki Nakamori, Stephanie Tomé, David Chitayat, Geneviève Gourdon, Charles A Thornton, Christopher E Pearson. Hum Mol Genet 2011
Arturo López Castel, Masayuki Nakamori, Stephanie Tomé, David Chitayat, Geneviève Gourdon, Charles A Thornton, Christopher E Pearson. Hum Mol Genet 2011
14
Xpa deficiency reduces CAG trinucleotide repeat instability in neuronal tissues in a mouse model of SCA1.
Leroy Hubert, Yunfu Lin, Vincent Dion, John H Wilson. Hum Mol Genet 2011
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24
Msh3 is a limiting factor in the formation of intergenerational CTG expansions in DM1 transgenic mice.
Laurent Foiry, Li Dong, Cédric Savouret, Laurence Hubert, Hein te Riele, Claudine Junien, Geneviève Gourdon. Hum Genet 2006
Laurent Foiry, Li Dong, Cédric Savouret, Laurence Hubert, Hein te Riele, Claudine Junien, Geneviève Gourdon. Hum Genet 2006
13
Genome-wide demethylation destabilizes CTG.CAG trinucleotide repeats in mammalian cells.
Vera Gorbunova, Andrei Seluanov, David Mittelman, John H Wilson. Hum Mol Genet 2004
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22
Somatic expansion of the Huntington's disease CAG repeat in the brain is associated with an earlier age of disease onset.
Meera Swami, Audrey E Hendricks, Tammy Gillis, Tiffany Massood, Jayalakshmi Mysore, Richard H Myers, Vanessa C Wheeler. Hum Mol Genet 2009
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13
DNA instability in postmitotic neurons.
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13
R loops stimulate genetic instability of CTG.CAG repeats.
Yunfu Lin, Sharon Y R Dent, John H Wilson, Robert D Wells, Marek Napierala. Proc Natl Acad Sci U S A 2010
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13
Somatic and gonadal mosaicism of the Huntington disease gene CAG repeat in brain and sperm.
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13
Non-ATG-initiated translation directed by microsatellite expansions.
Tao Zu, Brian Gibbens, Noelle S Doty, Mário Gomes-Pereira, Aline Huguet, Matthew D Stone, Jamie Margolis, Mark Peterson, Todd W Markowski, Melissa A C Ingram,[...]. Proc Natl Acad Sci U S A 2011
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13
CTCF regulates ataxin-7 expression through promotion of a convergently transcribed, antisense noncoding RNA.
Bryce L Sopher, Paula D Ladd, Victor V Pineda, Randell T Libby, Susan M Sunkin, James B Hurley, Cortlandt P Thienes, Terry Gaasterland, Galina N Filippova, Albert R La Spada. Neuron 2011
Bryce L Sopher, Paula D Ladd, Victor V Pineda, Randell T Libby, Susan M Sunkin, James B Hurley, Cortlandt P Thienes, Terry Gaasterland, Galina N Filippova, Albert R La Spada. Neuron 2011
13
The contribution of cis-elements to disease-associated repeat instability: clinical and experimental evidence.
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12
(CAG)(n)-hairpin DNA binds to Msh2-Msh3 and changes properties of mismatch recognition.
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12
Myotonic dystrophy mutation: an unstable CTG repeat in the 3' untranslated region of the gene.
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12
Cis-acting modifiers of expanded CAG/CTG triplet repeat expandability: associations with flanking GC content and proximity to CpG islands.
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13
Cohesin mediates transcriptional insulation by CCCTC-binding factor.
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12
Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation.
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12
Stoichiometry of base excision repair proteins correlates with increased somatic CAG instability in striatum over cerebellum in Huntington's disease transgenic mice.
Agathi-Vassiliki Goula, Brian R Berquist, David M Wilson, Vanessa C Wheeler, Yvon Trottier, Karine Merienne. PLoS Genet 2009
Agathi-Vassiliki Goula, Brian R Berquist, David M Wilson, Vanessa C Wheeler, Yvon Trottier, Karine Merienne. PLoS Genet 2009
12
Bidirectional transcription stimulates expansion and contraction of expanded (CTG)*(CAG) repeats.
Masayuki Nakamori, Christopher E Pearson, Charles A Thornton. Hum Mol Genet 2011
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17
Molecular basis of myotonic dystrophy: expansion of a trinucleotide (CTG) repeat at the 3' end of a transcript encoding a protein kinase family member.
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11
MSH2-dependent germinal CTG repeat expansions are produced continuously in spermatogonia from DM1 transgenic mice.
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14
Slipped (CTG)*(CAG) repeats can be correctly repaired, escape repair or undergo error-prone repair.
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11
Transgenic mice carrying large human genomic sequences with expanded CTG repeat mimic closely the DM CTG repeat intergenerational and somatic instability.
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11
Somatic instability of the CTG repeat in mice transgenic for the myotonic dystrophy region is age dependent but not correlated to the relative intertissue transcription levels and proliferative capacities.
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16
Trinucleotide expansion in haploid germ cells by gap repair.
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11
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.