Graham Pawelec, Evelyna Derhovanessian, Anis Larbi, Jan Strindhall, Anders Wikby. Rev Med Virol 2009
Times Cited: 220
Times Cited: 220
Times Cited
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Age-related change in peripheral blood T-lymphocyte subpopulations and cytomegalovirus infection in the very old: the Swedish longitudinal OCTO immune study.
J Olsson, A Wikby, B Johansson, S Löfgren, B O Nilsson, F G Ferguson. Mech Ageing Dev 2000
J Olsson, A Wikby, B Johansson, S Löfgren, B O Nilsson, F G Ferguson. Mech Ageing Dev 2000
17
Longitudinal studies of clonally expanded CD8 T cells reveal a repertoire shrinkage predicting mortality and an increased number of dysfunctional cytomegalovirus-specific T cells in the very elderly.
Sine Reker Hadrup, Jan Strindhall, Tania Køllgaard, Tina Seremet, Boo Johansson, Graham Pawelec, Per thor Straten, Anders Wikby. J Immunol 2006
Sine Reker Hadrup, Jan Strindhall, Tania Køllgaard, Tina Seremet, Boo Johansson, Graham Pawelec, Per thor Straten, Anders Wikby. J Immunol 2006
16
Inflamm-aging. An evolutionary perspective on immunosenescence.
C Franceschi, M Bonafè, S Valensin, F Olivieri, M De Luca, E Ottaviani, G De Benedictis. Ann N Y Acad Sci 2000
C Franceschi, M Bonafè, S Valensin, F Olivieri, M De Luca, E Ottaviani, G De Benedictis. Ann N Y Acad Sci 2000
16
Human T cell aging and the impact of persistent viral infections.
T Fülöp, A Larbi, G Pawelec. Front Immunol 2013
T Fülöp, A Larbi, G Pawelec. Front Immunol 2013
16
Biomarkers of human immunosenescence: impact of Cytomegalovirus infection.
Evelyna Derhovanessian, Anis Larbi, Graham Pawelec. Curr Opin Immunol 2009
Evelyna Derhovanessian, Anis Larbi, Graham Pawelec. Curr Opin Immunol 2009
15
Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals.
Naeem Khan, Naseer Shariff, Mark Cobbold, Rachel Bruton, Jenni A Ainsworth, Alan J Sinclair, Laxman Nayak, Paul A H Moss. J Immunol 2002
Naeem Khan, Naseer Shariff, Mark Cobbold, Rachel Bruton, Jenni A Ainsworth, Alan J Sinclair, Laxman Nayak, Paul A H Moss. J Immunol 2002
15
Cytomegalovirus-associated accumulation of late-differentiated CD4 T-cells correlates with poor humoral response to influenza vaccination.
Evelyna Derhovanessian, Heidi Theeten, Karin Hähnel, Pierre Van Damme, Nathalie Cools, Graham Pawelec. Vaccine 2013
Evelyna Derhovanessian, Heidi Theeten, Karin Hähnel, Pierre Van Damme, Nathalie Cools, Graham Pawelec. Vaccine 2013
18
Seropositivity to cytomegalovirus, inflammation, all-cause and cardiovascular disease-related mortality in the United States.
Amanda M Simanek, Jennifer Beam Dowd, Graham Pawelec, David Melzer, Ambarish Dutta, Allison E Aiello. PLoS One 2011
Amanda M Simanek, Jennifer Beam Dowd, Graham Pawelec, David Melzer, Ambarish Dutta, Allison E Aiello. PLoS One 2011
14
Long-term cytomegalovirus infection leads to significant changes in the composition of the CD8+ T-cell repertoire, which may be the basis for an imbalance in the cytokine production profile in elderly persons.
Giovanni Almanzar, Susanne Schwaiger, Brigitte Jenewein, Michael Keller, Dietmar Herndler-Brandstetter, Reinhard Würzner, Diether Schönitzer, Beatrix Grubeck-Loebenstein. J Virol 2005
Giovanni Almanzar, Susanne Schwaiger, Brigitte Jenewein, Michael Keller, Dietmar Herndler-Brandstetter, Reinhard Würzner, Diether Schönitzer, Beatrix Grubeck-Loebenstein. J Virol 2005
14
Cytomegalovirus infection: a driving force in human T cell immunosenescence.
Sven Koch, Anis Larbi, Dennis Ozcelik, Rafael Solana, Cécile Gouttefangeas, Sebastian Attig, Anders Wikby, Jan Strindhall, Claudio Franceschi, Graham Pawelec. Ann N Y Acad Sci 2007
Sven Koch, Anis Larbi, Dennis Ozcelik, Rafael Solana, Cécile Gouttefangeas, Sebastian Attig, Anders Wikby, Jan Strindhall, Claudio Franceschi, Graham Pawelec. Ann N Y Acad Sci 2007
14
Hallmark features of immunosenescence are absent in familial longevity.
Evelyna Derhovanessian, Andrea B Maier, Robert Beck, Gerhard Jahn, Karin Hähnel, P Eline Slagboom, Anton J M de Craen, Rudi G J Westendorp, Graham Pawelec. J Immunol 2010
Evelyna Derhovanessian, Andrea B Maier, Robert Beck, Gerhard Jahn, Karin Hähnel, P Eline Slagboom, Anton J M de Craen, Rudi G J Westendorp, Graham Pawelec. J Immunol 2010
13
Cytomegalovirus-seropositivity has a profound influence on the magnitude of major lymphoid subsets within healthy individuals.
S Chidrawar, N Khan, W Wei, A McLarnon, N Smith, L Nayak, P Moss. Clin Exp Immunol 2009
S Chidrawar, N Khan, W Wei, A McLarnon, N Smith, L Nayak, P Moss. Clin Exp Immunol 2009
13
Cytomegalovirus infection enhances the immune response to influenza.
David Furman, Vladimir Jojic, Shalini Sharma, Shai S Shen-Orr, Cesar J L Angel, Suna Onengut-Gumuscu, Brian A Kidd, Holden T Maecker, Patrick Concannon, Cornelia L Dekker,[...]. Sci Transl Med 2015
David Furman, Vladimir Jojic, Shalini Sharma, Shai S Shen-Orr, Cesar J L Angel, Suna Onengut-Gumuscu, Brian A Kidd, Holden T Maecker, Patrick Concannon, Cornelia L Dekker,[...]. Sci Transl Med 2015
13
An immune risk phenotype, cognitive impairment, and survival in very late life: impact of allostatic load in Swedish octogenarian and nonagenarian humans.
Anders Wikby, Frederick Ferguson, Rosalyn Forsey, Julie Thompson, Jan Strindhall, Sture Löfgren, Bengt-Olof Nilsson, Jan Ernerudh, Graham Pawelec, Boo Johansson. J Gerontol A Biol Sci Med Sci 2005
Anders Wikby, Frederick Ferguson, Rosalyn Forsey, Julie Thompson, Jan Strindhall, Sture Löfgren, Bengt-Olof Nilsson, Jan Ernerudh, Graham Pawelec, Boo Johansson. J Gerontol A Biol Sci Med Sci 2005
11
Expansions of peripheral blood CD8 T-lymphocyte subpopulations and an association with cytomegalovirus seropositivity in the elderly: the Swedish NONA immune study.
Anders Wikby, Boo Johansson, Jadwiga Olsson, Sture Löfgren, Bengt Olof Nilsson, Frederick Ferguson. Exp Gerontol 2002
Anders Wikby, Boo Johansson, Jadwiga Olsson, Sture Löfgren, Bengt Olof Nilsson, Frederick Ferguson. Exp Gerontol 2002
11
Lack of antibody production following immunization in old age: association with CD8(+)CD28(-) T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines.
Maria Saurwein-Teissl, Thomas L Lung, Florentine Marx, Claudio Gschösser, Esther Asch, Imrich Blasko, Walther Parson, Günther Böck, Diether Schönitzer, Emanuelle Trannoy,[...]. J Immunol 2002
Maria Saurwein-Teissl, Thomas L Lung, Florentine Marx, Claudio Gschösser, Esther Asch, Imrich Blasko, Walther Parson, Günther Böck, Diether Schönitzer, Emanuelle Trannoy,[...]. J Immunol 2002
11
Infection with cytomegalovirus but not herpes simplex virus induces the accumulation of late-differentiated CD4+ and CD8+ T-cells in humans.
Evelyna Derhovanessian, Andrea B Maier, Karin Hähnel, Robert Beck, Anton J M de Craen, Eline P Slagboom, Rudi G J Westendorp, Graham Pawelec. J Gen Virol 2011
Evelyna Derhovanessian, Andrea B Maier, Karin Hähnel, Robert Beck, Anton J M de Craen, Eline P Slagboom, Rudi G J Westendorp, Graham Pawelec. J Gen Virol 2011
11
The inverted CD4/CD8 ratio and associated parameters in 66-year-old individuals: the Swedish HEXA immune study.
J Strindhall, M Skog, J Ernerudh, M Bengner, S Löfgren, A Matussek, B O Nilsson, A Wikby. Age (Dordr) 2013
J Strindhall, M Skog, J Ernerudh, M Bengner, S Löfgren, A Matussek, B O Nilsson, A Wikby. Age (Dordr) 2013
11
Role of cytomegalovirus in the T cell changes seen in elderly individuals.
R J Looney, A Falsey, D Campbell, A Torres, J Kolassa, C Brower, R McCann, M Menegus, K McCormick, M Frampton,[...]. Clin Immunol 1999
R J Looney, A Falsey, D Campbell, A Torres, J Kolassa, C Brower, R McCann, M Menegus, K McCormick, M Frampton,[...]. Clin Immunol 1999
11
Association between cytomegalovirus infection, enhanced proinflammatory response and low level of anti-hemagglutinins during the anti-influenza vaccination--an impact of immunosenescence.
Piotr Trzonkowski, Jolanta Myśliwska, Ewa Szmit, Joanna Wieckiewicz, Krzysztof Lukaszuk, Lidia B Brydak, Magdalena Machała, Andrzej Myśliwski. Vaccine 2003
Piotr Trzonkowski, Jolanta Myśliwska, Ewa Szmit, Joanna Wieckiewicz, Krzysztof Lukaszuk, Lidia B Brydak, Magdalena Machała, Andrzej Myśliwski. Vaccine 2003
11
Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans.
Claudio Franceschi, Miriam Capri, Daniela Monti, Sergio Giunta, Fabiola Olivieri, Federica Sevini, Maria Panagiota Panourgia, Laura Invidia, Laura Celani, Maria Scurti,[...]. Mech Ageing Dev 2007
Claudio Franceschi, Miriam Capri, Daniela Monti, Sergio Giunta, Fabiola Olivieri, Federica Sevini, Maria Panagiota Panourgia, Laura Invidia, Laura Celani, Maria Scurti,[...]. Mech Ageing Dev 2007
11
Review of cytomegalovirus seroprevalence and demographic characteristics associated with infection.
Michael J Cannon, D Scott Schmid, Terri B Hyde. Rev Med Virol 2010
Michael J Cannon, D Scott Schmid, Terri B Hyde. Rev Med Virol 2010
11
Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects.
Andrew W Sylwester, Bridget L Mitchell, John B Edgar, Cara Taormina, Christian Pelte, Franziska Ruchti, Paul R Sleath, Kenneth H Grabstein, Nancy A Hosken, Florian Kern,[...]. J Exp Med 2005
Andrew W Sylwester, Bridget L Mitchell, John B Edgar, Cara Taormina, Christian Pelte, Franziska Ruchti, Paul R Sleath, Kenneth H Grabstein, Nancy A Hosken, Florian Kern,[...]. J Exp Med 2005
10
Herpesvirus-specific CD8 T cell immunity in old age: cytomegalovirus impairs the response to a coresident EBV infection.
Naeem Khan, Andrew Hislop, Nancy Gudgeon, Mark Cobbold, Rajiv Khanna, Laxman Nayak, Alan B Rickinson, Paul A H Moss. J Immunol 2004
Naeem Khan, Andrew Hislop, Nancy Gudgeon, Mark Cobbold, Rajiv Khanna, Laxman Nayak, Alan B Rickinson, Paul A H Moss. J Immunol 2004
10
Rudimentary signs of immunosenescence in Cytomegalovirus-seropositive healthy young adults.
James E Turner, John P Campbell, Kate M Edwards, Lauren J Howarth, Graham Pawelec, Sarah Aldred, Paul Moss, Mark T Drayson, Victoria E Burns, Jos A Bosch. Age (Dordr) 2014
James E Turner, John P Campbell, Kate M Edwards, Lauren J Howarth, Graham Pawelec, Sarah Aldred, Paul Moss, Mark T Drayson, Victoria E Burns, Jos A Bosch. Age (Dordr) 2014
18
Chronic herpesvirus reactivation occurs in aging.
Raymond P Stowe, Elena V Kozlova, Deborah L Yetman, Dennis M Walling, James S Goodwin, Ronald Glaser. Exp Gerontol 2007
Raymond P Stowe, Elena V Kozlova, Deborah L Yetman, Dennis M Walling, James S Goodwin, Ronald Glaser. Exp Gerontol 2007
10
Cytomegalovirus infection is associated with increased mortality in the older population.
George M Savva, Annette Pachnio, Baksho Kaul, Kevin Morgan, Felicia A Huppert, Carol Brayne, Paul A H Moss. Aging Cell 2013
George M Savva, Annette Pachnio, Baksho Kaul, Kevin Morgan, Felicia A Huppert, Carol Brayne, Paul A H Moss. Aging Cell 2013
10
Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections.
Victor Appay, P Rod Dunbar, Margaret Callan, Paul Klenerman, Geraldine M A Gillespie, Laura Papagno, Graham S Ogg, Abigail King, Franziska Lechner, Celsa A Spina,[...]. Nat Med 2002
Victor Appay, P Rod Dunbar, Margaret Callan, Paul Klenerman, Geraldine M A Gillespie, Laura Papagno, Graham S Ogg, Abigail King, Franziska Lechner, Celsa A Spina,[...]. Nat Med 2002
9
CD28 extinction in human T cells: altered functions and the program of T-cell senescence.
Abbe N Vallejo. Immunol Rev 2005
Abbe N Vallejo. Immunol Rev 2005
9
Cytomegalovirus infection and the risk of mortality and frailty in older women: a prospective observational cohort study.
George C Wang, Wen Hong L Kao, Peter Murakami, Qian-Li Xue, Roger B Chiou, Barbara Detrick, John F McDyer, Richard D Semba, Vincenzo Casolaro, Jeremy D Walston,[...]. Am J Epidemiol 2010
George C Wang, Wen Hong L Kao, Peter Murakami, Qian-Li Xue, Roger B Chiou, Barbara Detrick, John F McDyer, Richard D Semba, Vincenzo Casolaro, Jeremy D Walston,[...]. Am J Epidemiol 2010
9
Seropositivity and higher immunoglobulin g antibody levels against cytomegalovirus are associated with mortality in the population-based European prospective investigation of Cancer-Norfolk cohort.
Effrossyni Gkrania-Klotsas, Claudia Langenberg, Stephen J Sharp, Robert Luben, Kay-Tee Khaw, Nicholas J Wareham. Clin Infect Dis 2013
Effrossyni Gkrania-Klotsas, Claudia Langenberg, Stephen J Sharp, Robert Luben, Kay-Tee Khaw, Nicholas J Wareham. Clin Infect Dis 2013
14
Cytomegalovirus antibody levels, inflammation, and mortality among elderly Latinos over 9 years of follow-up.
Eric T Roberts, Mary N Haan, Jennifer Beam Dowd, Allison E Aiello. Am J Epidemiol 2010
Eric T Roberts, Mary N Haan, Jennifer Beam Dowd, Allison E Aiello. Am J Epidemiol 2010
9
Chronic cytomegalovirus infection and inflammation are associated with prevalent frailty in community-dwelling older women.
Heidi N Schmaltz, Linda P Fried, Qian-Li Xue, Jeremy Walston, Sean X Leng, Richard D Semba. J Am Geriatr Soc 2005
Heidi N Schmaltz, Linda P Fried, Qian-Li Xue, Jeremy Walston, Sean X Leng, Richard D Semba. J Am Geriatr Soc 2005
9
Memory inflation: continuous accumulation of antiviral CD8+ T cells over time.
Urs Karrer, Sophie Sierro, Markus Wagner, Annette Oxenius, Hartmut Hengel, Ulrich H Koszinowski, Rodney E Phillips, Paul Klenerman. J Immunol 2003
Urs Karrer, Sophie Sierro, Markus Wagner, Annette Oxenius, Hartmut Hengel, Ulrich H Koszinowski, Rodney E Phillips, Paul Klenerman. J Immunol 2003
9
Multiparameter flow cytometric analysis of CD4 and CD8 T cell subsets in young and old people.
Sven Koch, Anis Larbi, Evelyna Derhovanessian, Dennis Ozcelik, Elissaveta Naumova, Graham Pawelec. Immun Ageing 2008
Sven Koch, Anis Larbi, Evelyna Derhovanessian, Dennis Ozcelik, Elissaveta Naumova, Graham Pawelec. Immun Ageing 2008
8
The aging of the immune system.
Daniela Weiskopf, Birgit Weinberger, Beatrix Grubeck-Loebenstein. Transpl Int 2009
Daniela Weiskopf, Birgit Weinberger, Beatrix Grubeck-Loebenstein. Transpl Int 2009
8
Changes in CD8 and CD4 lymphocyte subsets, T cell proliferation responses and non-survival in the very old: the Swedish longitudinal OCTO-immune study.
A Wikby, P Maxson, J Olsson, B Johansson, F G Ferguson. Mech Ageing Dev 1998
A Wikby, P Maxson, J Olsson, B Johansson, F G Ferguson. Mech Ageing Dev 1998
8
Antibody response to influenza vaccination in the elderly: a quantitative review.
Katherine Goodwin, Cécile Viboud, Lone Simonsen. Vaccine 2006
Katherine Goodwin, Cécile Viboud, Lone Simonsen. Vaccine 2006
8
Latent infection with cytomegalovirus is associated with poor memory CD4 responses to influenza A core proteins in the elderly.
Evelyna Derhovanessian, Andrea B Maier, Karin Hähnel, Janet E McElhaney, Eline P Slagboom, Graham Pawelec. J Immunol 2014
Evelyna Derhovanessian, Andrea B Maier, Karin Hähnel, Janet E McElhaney, Eline P Slagboom, Graham Pawelec. J Immunol 2014
11
The impact of CMV infection on survival in older humans.
Graham Pawelec, Janet E McElhaney, Allison E Aiello, Evelyna Derhovanessian. Curr Opin Immunol 2012
Graham Pawelec, Janet E McElhaney, Allison E Aiello, Evelyna Derhovanessian. Curr Opin Immunol 2012
8
Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals.
J J Goronzy, J W Fulbright, C S Crowson, G A Poland, W M O'Fallon, C M Weyand. J Virol 2001
J J Goronzy, J W Fulbright, C S Crowson, G A Poland, W M O'Fallon, C M Weyand. J Virol 2001
7
Immune parameters in a longitudinal study of a very old population of Swedish people: a comparison between survivors and nonsurvivors.
F G Ferguson, A Wikby, P Maxson, J Olsson, B Johansson. J Gerontol A Biol Sci Med Sci 1995
F G Ferguson, A Wikby, P Maxson, J Olsson, B Johansson. J Gerontol A Biol Sci Med Sci 1995
7
Phenotype and function of human T lymphocyte subsets: consensus and issues.
Victor Appay, Rene A W van Lier, Federica Sallusto, Mario Roederer. Cytometry A 2008
Victor Appay, Rene A W van Lier, Federica Sallusto, Mario Roederer. Cytometry A 2008
7
Lower proportion of naïve peripheral CD8+ T cells and an unopposed pro-inflammatory response to human Cytomegalovirus proteins in vitro are associated with longer survival in very elderly people.
Evelyna Derhovanessian, Andrea B Maier, Karin Hähnel, Henning Zelba, Anton J M de Craen, Helene Roelofs, Eline P Slagboom, Rudi G J Westendorp, Graham Pawelec. Age (Dordr) 2013
Evelyna Derhovanessian, Andrea B Maier, Karin Hähnel, Henning Zelba, Anton J M de Craen, Helene Roelofs, Eline P Slagboom, Rudi G J Westendorp, Graham Pawelec. Age (Dordr) 2013
13
The age-related increase in low-grade systemic inflammation (Inflammaging) is not driven by cytomegalovirus infection.
David B Bartlett, Charlotte M Firth, Anna C Phillips, Paul Moss, Daniel Baylis, Holly Syddall, Avan A Sayer, Cyrus Cooper, Janet M Lord. Aging Cell 2012
David B Bartlett, Charlotte M Firth, Anna C Phillips, Paul Moss, Daniel Baylis, Holly Syddall, Avan A Sayer, Cyrus Cooper, Janet M Lord. Aging Cell 2012
7
Innate immunosenescence: effect of aging on cells and receptors of the innate immune system in humans.
Rafael Solana, Raquel Tarazona, Inmaculada Gayoso, Olivier Lesur, Gilles Dupuis, Tamas Fulop. Semin Immunol 2012
Rafael Solana, Raquel Tarazona, Inmaculada Gayoso, Olivier Lesur, Gilles Dupuis, Tamas Fulop. Semin Immunol 2012
7
Aging and cytomegalovirus infection differentially and jointly affect distinct circulating T cell subsets in humans.
Anne M Wertheimer, Michael S Bennett, Byung Park, Jennifer L Uhrlaub, Carmine Martinez, Vesna Pulko, Noreen L Currier, Dragana Nikolich-Žugich, Jeffrey Kaye, Janko Nikolich-Žugich. J Immunol 2014
Anne M Wertheimer, Michael S Bennett, Byung Park, Jennifer L Uhrlaub, Carmine Martinez, Vesna Pulko, Noreen L Currier, Dragana Nikolich-Žugich, Jeffrey Kaye, Janko Nikolich-Žugich. J Immunol 2014
7
CMV latent infection improves CD8+ T response to SEB due to expansion of polyfunctional CD57+ cells in young individuals.
Alejandra Pera, Carmen Campos, Alonso Corona, Beatriz Sanchez-Correa, Raquel Tarazona, Anis Larbi, Rafael Solana. PLoS One 2014
Alejandra Pera, Carmen Campos, Alonso Corona, Beatriz Sanchez-Correa, Raquel Tarazona, Anis Larbi, Rafael Solana. PLoS One 2014
13
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.