Francesco Ferraguti, Luca Crepaldi, Ferdinando Nicoletti. Pharmacol Rev 2008
Times Cited: 146
Times Cited: 146
Times Cited
Times Co-cited
Similarity
Metabotropic glutamate receptors: from the workbench to the bedside.
F Nicoletti, J Bockaert, G L Collingridge, P J Conn, F Ferraguti, D D Schoepp, J T Wroblewski, J P Pin. Neuropharmacology 2011
F Nicoletti, J Bockaert, G L Collingridge, P J Conn, F Ferraguti, D D Schoepp, J T Wroblewski, J P Pin. Neuropharmacology 2011
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Metabotropic glutamate receptors: physiology, pharmacology, and disease.
Colleen M Niswender, P Jeffrey Conn. Annu Rev Pharmacol Toxicol 2010
Colleen M Niswender, P Jeffrey Conn. Annu Rev Pharmacol Toxicol 2010
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Pharmacology and functions of metabotropic glutamate receptors.
P J Conn, J P Pin. Annu Rev Pharmacol Toxicol 1997
P J Conn, J P Pin. Annu Rev Pharmacol Toxicol 1997
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Differential localization of phosphoinositide-linked metabotropic glutamate receptor (mGluR1) and the inositol 1,4,5-trisphosphate receptor in rat brain.
M Fotuhi, A H Sharp, C E Glatt, P M Hwang, M von Krosigk, S H Snyder, T M Dawson. J Neurosci 1993
M Fotuhi, A H Sharp, C E Glatt, P M Hwang, M von Krosigk, S H Snyder, T M Dawson. J Neurosci 1993
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Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice.
A Aiba, M Kano, C Chen, M E Stanton, G D Fox, K Herrup, T A Zwingman, S Tonegawa. Cell 1994
A Aiba, M Kano, C Chen, M E Stanton, G D Fox, K Herrup, T A Zwingman, S Tonegawa. Cell 1994
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Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1.
F Conquet, Z I Bashir, C H Davies, H Daniel, F Ferraguti, F Bordi, K Franz-Bacon, A Reggiani, V Matarese, F Condé. Nature 1994
F Conquet, Z I Bashir, C H Davies, H Daniel, F Ferraguti, F Bordi, K Franz-Bacon, A Reggiani, V Matarese, F Condé. Nature 1994
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Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptors.
J C Tu, B Xiao, J P Yuan, A A Lanahan, K Leoffert, M Li, D J Linden, P F Worley. Neuron 1998
J C Tu, B Xiao, J P Yuan, A A Lanahan, K Leoffert, M Li, D J Linden, P F Worley. Neuron 1998
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Cellular localization of a metabotropic glutamate receptor in rat brain.
L J Martin, C D Blackstone, R L Huganir, D L Price. Neuron 1992
L J Martin, C D Blackstone, R L Huganir, D L Price. Neuron 1992
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Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice.
A Aiba, C Chen, K Herrup, C Rosenmund, C F Stevens, S Tonegawa. Cell 1994
A Aiba, C Chen, K Herrup, C Rosenmund, C F Stevens, S Tonegawa. Cell 1994
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Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system.
D D Schoepp. J Pharmacol Exp Ther 2001
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Synthesis, characterization, and monkey PET studies of [¹⁸F]MK-1312, a PET tracer for quantification of mGluR1 receptor occupancy by MK-5435.
Eric D Hostetler, Waisi Eng, Aniket D Joshi, Sandra Sanabria-Bohórquez, Hiroshi Kawamoto, Satoru Ito, Stacey O'Malley, Stephen Krause, Christine Ryan, Shil Patel,[...]. Synapse 2011
Eric D Hostetler, Waisi Eng, Aniket D Joshi, Sandra Sanabria-Bohórquez, Hiroshi Kawamoto, Satoru Ito, Stacey O'Malley, Stephen Krause, Christine Ryan, Shil Patel,[...]. Synapse 2011
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The metabotropic glutamate receptor (mGluR1 alpha) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction.
A Baude, Z Nusser, J D Roberts, E Mulvihill, R A McIlhinney, P Somogyi. Neuron 1993
A Baude, Z Nusser, J D Roberts, E Mulvihill, R A McIlhinney, P Somogyi. Neuron 1993
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A new approach to analyze cell surface protein complexes reveals specific heterodimeric metabotropic glutamate receptors.
Etienne Doumazane, Pauline Scholler, Jurriaan M Zwier, Eric Trinquet, Philippe Rondard, Jean-Philippe Pin. FASEB J 2011
Etienne Doumazane, Pauline Scholler, Jurriaan M Zwier, Eric Trinquet, Philippe Rondard, Jean-Philippe Pin. FASEB J 2011
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Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins.
J C Tu, B Xiao, S Naisbitt, J P Yuan, R S Petralia, P Brakeman, A Doan, V K Aakalu, A A Lanahan, M Sheng,[...]. Neuron 1999
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11
mGluR1 in cerebellar Purkinje cells essential for long-term depression, synapse elimination, and motor coordination.
T Ichise, M Kano, K Hashimoto, D Yanagihara, K Nakao, R Shigemoto, M Katsuki, A Aiba. Science 2000
T Ichise, M Kano, K Hashimoto, D Yanagihara, K Nakao, R Shigemoto, M Katsuki, A Aiba. Science 2000
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Homer: a protein that selectively binds metabotropic glutamate receptors.
P R Brakeman, A A Lanahan, R O'Brien, K Roche, C A Barnes, R L Huganir, P F Worley. Nature 1997
P R Brakeman, A A Lanahan, R O'Brien, K Roche, C A Barnes, R L Huganir, P F Worley. Nature 1997
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Sequence and expression of a metabotropic glutamate receptor.
M Masu, Y Tanabe, K Tsuchida, R Shigemoto, S Nakanishi. Nature 1991
M Masu, Y Tanabe, K Tsuchida, R Shigemoto, S Nakanishi. Nature 1991
10
Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction.
T Abe, H Sugihara, H Nawa, R Shigemoto, N Mizuno, S Nakanishi. J Biol Chem 1992
T Abe, H Sugihara, H Nawa, R Shigemoto, N Mizuno, S Nakanishi. J Biol Chem 1992
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The metabotropic glutamate receptors: structure and functions.
J P Pin, R Duvoisin. Neuropharmacology 1995
J P Pin, R Duvoisin. Neuropharmacology 1995
10
Paraneoplastic cerebellar ataxia due to autoantibodies against a glutamate receptor.
P Sillevis Smitt, A Kinoshita, B De Leeuw, W Moll, M Coesmans, D Jaarsma, S Henzen-Logmans, C Vecht, C De Zeeuw, N Sekiyama,[...]. N Engl J Med 2000
P Sillevis Smitt, A Kinoshita, B De Leeuw, W Moll, M Coesmans, D Jaarsma, S Henzen-Logmans, C Vecht, C De Zeeuw, N Sekiyama,[...]. N Engl J Med 2000
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Perisynaptic location of metabotropic glutamate receptors mGluR1 and mGluR5 on dendrites and dendritic spines in the rat hippocampus.
R Lujan, Z Nusser, J D Roberts, R Shigemoto, P Somogyi. Eur J Neurosci 1996
R Lujan, Z Nusser, J D Roberts, R Shigemoto, P Somogyi. Eur J Neurosci 1996
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Pharmacological enhancement of mGlu1 metabotropic glutamate receptors causes a prolonged symptomatic benefit in a mouse model of spinocerebellar ataxia type 1.
Serena Notartomaso, Cristina Zappulla, Francesca Biagioni, Milena Cannella, Domenico Bucci, Giada Mascio, Pamela Scarselli, Francesco Fazio, Filippo Weisz, Luana Lionetto,[...]. Mol Brain 2013
Serena Notartomaso, Cristina Zappulla, Francesca Biagioni, Milena Cannella, Domenico Bucci, Giada Mascio, Pamela Scarselli, Francesco Fazio, Filippo Weisz, Luana Lionetto,[...]. Mol Brain 2013
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2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist.
F Gasparini, K Lingenhöhl, N Stoehr, P J Flor, M Heinrich, I Vranesic, M Biollaz, H Allgeier, R Heckendorn, S Urwyler,[...]. Neuropharmacology 1999
F Gasparini, K Lingenhöhl, N Stoehr, P J Flor, M Heinrich, I Vranesic, M Biollaz, H Allgeier, R Heckendorn, S Urwyler,[...]. Neuropharmacology 1999
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Regulation of neurotransmitter release by metabotropic glutamate receptors.
J Cartmell, D D Schoepp. J Neurochem 2000
J Cartmell, D D Schoepp. J Neurochem 2000
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Regulation of metabotropic glutamate receptor signaling, desensitization and endocytosis.
Gurpreet K Dhami, Stephen S G Ferguson. Pharmacol Ther 2006
Gurpreet K Dhami, Stephen S G Ferguson. Pharmacol Ther 2006
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Signal transduction and pharmacological characteristics of a metabotropic glutamate receptor, mGluR1, in transfected CHO cells.
I Aramori, S Nakanishi. Neuron 1992
I Aramori, S Nakanishi. Neuron 1992
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Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptors.
E Hermans, R A Challiss. Biochem J 2001
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Simplified reference tissue model for PET receptor studies.
A A Lammertsma, S P Hume. Neuroimage 1996
A A Lammertsma, S P Hume. Neuroimage 1996
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Group 1 mGluR-dependent synaptic long-term depression: mechanisms and implications for circuitry and disease.
Christian Lüscher, Kimberly M Huber. Neuron 2010
Christian Lüscher, Kimberly M Huber. Neuron 2010
9
Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1) in the central nervous system: an in situ hybridization study in adult and developing rat.
R Shigemoto, S Nakanishi, N Mizuno. J Comp Neurol 1992
R Shigemoto, S Nakanishi, N Mizuno. J Comp Neurol 1992
9
Radiosynthesis and evaluation of [11C]YM-202074 as a PET ligand for imaging the metabotropic glutamate receptor type 1.
Kazuhiko Yanamoto, Fujiko Konno, Chika Odawara, Tomoteru Yamasaki, Kazunori Kawamura, Akiko Hatori, Joji Yui, Hidekatsu Wakizaka, Nobuki Nengaki, Makoto Takei,[...]. Nucl Med Biol 2010
Kazuhiko Yanamoto, Fujiko Konno, Chika Odawara, Tomoteru Yamasaki, Kazunori Kawamura, Akiko Hatori, Joji Yui, Hidekatsu Wakizaka, Nobuki Nengaki, Makoto Takei,[...]. Nucl Med Biol 2010
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Synthesis, in vitro and in vivo evaluation of [11C]MMTP: a potential PET ligand for mGluR1 receptors.
Jaya Prabhakaran, Vattoly J Majo, Matthew S Milak, Suham A Kassir, Mikael Palner, Lyudmila Savenkova, Pratap Mali, Victoria Arango, J John Mann, Ramin V Parsey,[...]. Bioorg Med Chem Lett 2010
Jaya Prabhakaran, Vattoly J Majo, Matthew S Milak, Suham A Kassir, Mikael Palner, Lyudmila Savenkova, Pratap Mali, Victoria Arango, J John Mann, Ramin V Parsey,[...]. Bioorg Med Chem Lett 2010
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Differential plasma membrane distribution of metabotropic glutamate receptors mGluR1 alpha, mGluR2 and mGluR5, relative to neurotransmitter release sites.
R Luján, J D Roberts, R Shigemoto, H Ohishi, P Somogyi. J Chem Neuroanat 1997
R Luján, J D Roberts, R Shigemoto, H Ohishi, P Somogyi. J Chem Neuroanat 1997
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Metabotropic glutamate receptors: electrophysiological properties and role in plasticity.
R Anwyl. Brain Res Brain Res Rev 1999
R Anwyl. Brain Res Brain Res Rev 1999
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Glutamate receptors: brain function and signal transduction.
S Nakanishi, Y Nakajima, M Masu, Y Ueda, K Nakahara, D Watanabe, S Yamaguchi, S Kawabata, M Okada. Brain Res Brain Res Rev 1998
S Nakanishi, Y Nakajima, M Masu, Y Ueda, K Nakahara, D Watanabe, S Yamaguchi, S Kawabata, M Okada. Brain Res Brain Res Rev 1998
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Metabotropic glutamate receptors 1 and 5 differentially regulate CA1 pyramidal cell function.
G Mannaioni, M J Marino, O Valenti, S F Traynelis, P J Conn. J Neurosci 2001
G Mannaioni, M J Marino, O Valenti, S F Traynelis, P J Conn. J Neurosci 2001
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Radiosynthesis and preliminary evaluation of 4-[18F]fluoro-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methylbenzamide as a new positron emission tomography ligand for metabotropic glutamate receptor subtype 1.
Tomoteru Yamasaki, Masayuki Fujinaga, Yuichiro Yoshida, Katsushi Kumata, Joji Yui, Kazunori Kawamura, Akiko Hatori, Toshimitsu Fukumura, Ming-Rong Zhang. Bioorg Med Chem Lett 2011
Tomoteru Yamasaki, Masayuki Fujinaga, Yuichiro Yoshida, Katsushi Kumata, Joji Yui, Kazunori Kawamura, Akiko Hatori, Toshimitsu Fukumura, Ming-Rong Zhang. Bioorg Med Chem Lett 2011
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Distribution of metabotropic glutamate receptor mGluR3 in the mouse CNS: differential location relative to pre- and postsynaptic sites.
Y Tamaru, S Nomura, N Mizuno, R Shigemoto. Neuroscience 2001
Y Tamaru, S Nomura, N Mizuno, R Shigemoto. Neuroscience 2001
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Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins.
B Xiao, J C Tu, R S Petralia, J P Yuan, A Doan, C D Breder, A Ruggiero, A A Lanahan, R J Wenthold, P F Worley. Neuron 1998
B Xiao, J C Tu, R S Petralia, J P Yuan, A Doan, C D Breder, A Ruggiero, A A Lanahan, R J Wenthold, P F Worley. Neuron 1998
8
Preclinical and the first clinical studies on [11C]ITMM for mapping metabotropic glutamate receptor subtype 1 by positron emission tomography.
Jun Toyohara, Muneyuki Sakata, Masayuki Fujinaga, Tomoteru Yamasaki, Keiichi Oda, Kenji Ishii, Ming Rong Zhang, Cristina Maria Moriguchi Jeckel, Kiichi Ishiwata. Nucl Med Biol 2013
Jun Toyohara, Muneyuki Sakata, Masayuki Fujinaga, Tomoteru Yamasaki, Keiichi Oda, Kenji Ishii, Ming Rong Zhang, Cristina Maria Moriguchi Jeckel, Kiichi Ishiwata. Nucl Med Biol 2013
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Type-1 metabotropic glutamate receptor in cerebellar Purkinje cells: a key molecule responsible for long-term depression, endocannabinoid signalling and synapse elimination.
Masanobu Kano, Kouichi Hashimoto, Toshihide Tabata. Philos Trans R Soc Lond B Biol Sci 2008
Masanobu Kano, Kouichi Hashimoto, Toshihide Tabata. Philos Trans R Soc Lond B Biol Sci 2008
9
Initial human PET studies of metabotropic glutamate receptor type 1 ligand 11C-ITMM.
Jun Toyohara, Muneyuki Sakata, Keiichi Oda, Kenji Ishii, Kimiteru Ito, Mikio Hiura, Masayuki Fujinaga, Tomoteru Yamasaki, Ming Rong Zhang, Kiichi Ishiwata. J Nucl Med 2013
Jun Toyohara, Muneyuki Sakata, Keiichi Oda, Kenji Ishii, Kimiteru Ito, Mikio Hiura, Masayuki Fujinaga, Tomoteru Yamasaki, Ming Rong Zhang, Kiichi Ishiwata. J Nucl Med 2013
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Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain.
R Shigemoto, S Nomura, H Ohishi, H Sugihara, S Nakanishi, N Mizuno. Neurosci Lett 1993
R Shigemoto, S Nomura, H Ohishi, H Sugihara, S Nakanishi, N Mizuno. Neurosci Lett 1993
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Metabotropic glutamate receptors as novel targets for anxiety and stress disorders.
Chad J Swanson, Mark Bures, Michael P Johnson, Anni-Maija Linden, James A Monn, Darryle D Schoepp. Nat Rev Drug Discov 2005
Chad J Swanson, Mark Bures, Michael P Johnson, Anni-Maija Linden, James A Monn, Darryle D Schoepp. Nat Rev Drug Discov 2005
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Neuroprotective effects of the selective type 1 metabotropic glutamate receptor antagonist YM-202074 in rat stroke models.
Atsuyuki Kohara, Masayasu Takahashi, Shin-Ichi Yatsugi, Seiji Tamura, Yoshitsugu Shitaka, Satoshi Hayashibe, Shigeki Kawabata, Masamichi Okada. Brain Res 2008
Atsuyuki Kohara, Masayasu Takahashi, Shin-Ichi Yatsugi, Seiji Tamura, Yoshitsugu Shitaka, Satoshi Hayashibe, Shigeki Kawabata, Masamichi Okada. Brain Res 2008
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JNJ16259685, a highly potent, selective and systemically active mGlu1 receptor antagonist.
Hilde Lavreysen, Ria Wouters, François Bischoff, Sandrina Nóbrega Pereira, Xavier Langlois, Saskia Blokland, Marijke Somers, Lieve Dillen, Anne S J Lesage. Neuropharmacology 2004
Hilde Lavreysen, Ria Wouters, François Bischoff, Sandrina Nóbrega Pereira, Xavier Langlois, Saskia Blokland, Marijke Somers, Lieve Dillen, Anne S J Lesage. Neuropharmacology 2004
7
Synthesis and evaluation of 6-[1-(2-[(18)F]fluoro-3-pyridyl)-5-methyl-1H-1,2,3-triazol-4-yl]quinoline for positron emission tomography imaging of the metabotropic glutamate receptor type 1 in brain.
Masayuki Fujinaga, Tomoteru Yamasaki, Kazunori Kawamura, Katsushi Kumata, Akiko Hatori, Joji Yui, Kazuhiko Yanamoto, Yuichiro Yoshida, Masanao Ogawa, Nobuki Nengaki,[...]. Bioorg Med Chem 2011
Masayuki Fujinaga, Tomoteru Yamasaki, Kazunori Kawamura, Katsushi Kumata, Akiko Hatori, Joji Yui, Kazuhiko Yanamoto, Yuichiro Yoshida, Masanao Ogawa, Nobuki Nengaki,[...]. Bioorg Med Chem 2011
22
A positron emission tomography radioligand for the in vivo labeling of metabotropic glutamate 1 receptor: (3-ethyl-2-[11C]methyl-6-quinolinyl)(cis- 4-methoxycyclohexyl)methanone.
Yiyun Huang, Raj Narendran, François Bischoff, Ningning Guo, Zhihong Zhu, Sung-A Bae, Anne S Lesage, Marc Laruelle. J Med Chem 2005
Yiyun Huang, Raj Narendran, François Bischoff, Ningning Guo, Zhihong Zhu, Sung-A Bae, Anne S Lesage, Marc Laruelle. J Med Chem 2005
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Subsynaptic segregation of metabotropic and ionotropic glutamate receptors as revealed by immunogold localization.
Z Nusser, E Mulvihill, P Streit, P Somogyi. Neuroscience 1994
Z Nusser, E Mulvihill, P Streit, P Somogyi. Neuroscience 1994
7
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.