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The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.
Jinghui Zhang, Li Ding, Linda Holmfeldt, Gang Wu, Sue L Heatley, Debbie Payne-Turner, John Easton, Xiang Chen, Jianmin Wang, Michael Rusch,[...]. Nature 2012
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The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia.
Yu Liu, John Easton, Ying Shao, Jamie Maciaszek, Zhaoming Wang, Mark R Wilkinson, Kelly McCastlain, Michael Edmonson, Stanley B Pounds, Lei Shi,[...]. Nat Genet 2017
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Early T-cell precursor acute lymphoblastic leukemia/lymphoma (ETP-ALL/LBL) in adolescents and adults: a high-risk subtype.
Nitin Jain, Audrey V Lamb, Susan O'Brien, Farhad Ravandi, Marina Konopleva, Elias Jabbour, Zhuang Zuo, Jeffrey Jorgensen, Pei Lin, Sherry Pierce,[...]. Blood 2016
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The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia.
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Early Response-Based Therapy Stratification Improves Survival in Adult Early Thymic Precursor Acute Lymphoblastic Leukemia: A Group for Research on Adult Acute Lymphoblastic Leukemia Study.
Jonathan Bond, Carlos Graux, Ludovic Lhermitte, Diane Lara, Thomas Cluzeau, Thibaut Leguay, Agata Cieslak, Amélie Trinquand, Cedric Pastoret, Mohamed Belhocine,[...]. J Clin Oncol 2017
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Outcome for children and young people with Early T-cell precursor acute lymphoblastic leukaemia treated on a contemporary protocol, UKALL 2003.
Katharine Patrick, Rachel Wade, Nick Goulden, Chris Mitchell, Anthony V Moorman, Clare Rowntree, Sarah Jenkinson, Rachael Hough, Ajay Vora. Br J Haematol 2014
Katharine Patrick, Rachel Wade, Nick Goulden, Chris Mitchell, Anthony V Moorman, Clare Rowntree, Sarah Jenkinson, Rachael Hough, Ajay Vora. Br J Haematol 2014
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Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia.
Adolfo A Ferrando, Donna S Neuberg, Jane Staunton, Mignon L Loh, Christine Huard, Susana C Raimondi, Fred G Behm, Ching Hon Pui, James R Downing, D Gary Gilliland,[...]. Cancer Cell 2002
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The genetics and mechanisms of T cell acute lymphoblastic leukaemia.
Laura Belver, Adolfo Ferrando. Nat Rev Cancer 2016
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Maturation stage of T-cell acute lymphoblastic leukemia determines BCL-2 versus BCL-XL dependence and sensitivity to ABT-199.
Triona Ni Chonghaile, Justine E Roderick, Cian Glenfield, Jeremy Ryan, Stephen E Sallan, Lewis B Silverman, Mignon L Loh, Stephen P Hunger, Brent Wood, Daniel J DeAngelo,[...]. Cancer Discov 2014
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Clinical significance of early T-cell precursor acute lymphoblastic leukaemia: results of the Tokyo Children's Cancer Study Group Study L99-15.
Takeshi Inukai, Nobutaka Kiyokawa, Dario Campana, Elaine Coustan-Smith, Akira Kikuchi, Miyuki Kobayashi, Hiroyuki Takahashi, Katsuyoshi Koh, Atsushi Manabe, Masaaki Kumagai,[...]. Br J Haematol 2012
Takeshi Inukai, Nobutaka Kiyokawa, Dario Campana, Elaine Coustan-Smith, Akira Kikuchi, Miyuki Kobayashi, Hiroyuki Takahashi, Katsuyoshi Koh, Atsushi Manabe, Masaaki Kumagai,[...]. Br J Haematol 2012
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Clinical and molecular characterization of early T-cell precursor leukemia: a high-risk subgroup in adult T-ALL with a high frequency of FLT3 mutations.
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Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia.
Kathryn G Roberts, Yongjin Li, Debbie Payne-Turner, Richard C Harvey, Yung-Li Yang, Deqing Pei, Kelly McCastlain, Li Ding, Charles Lu, Guangchun Song,[...]. N Engl J Med 2014
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Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia.
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Proposals for the immunological classification of acute leukemias. European Group for the Immunological Characterization of Leukemias (EGIL).
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Toward a NOTCH1/FBXW7/RAS/PTEN-based oncogenetic risk classification of adult T-cell acute lymphoblastic leukemia: a Group for Research in Adult Acute Lymphoblastic Leukemia study.
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Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations.
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Efficacy of JAK/STAT pathway inhibition in murine xenograft models of early T-cell precursor (ETP) acute lymphoblastic leukemia.
Shannon L Maude, Sibasish Dolai, Cristina Delgado-Martin, Tiffaney Vincent, Alissa Robbins, Arthavan Selvanathan, Theresa Ryan, Junior Hall, Andrew C Wood, Sarah K Tasian,[...]. Blood 2015
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Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Andrew P Weng, Adolfo A Ferrando, Woojoong Lee, John P Morris, Lewis B Silverman, Cheryll Sanchez-Irizarry, Stephen C Blacklow, A Thomas Look, Jon C Aster. Science 2004
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The genetic basis and cell of origin of mixed phenotype acute leukaemia.
Thomas B Alexander, Zhaohui Gu, Ilaria Iacobucci, Kirsten Dickerson, John K Choi, Beisi Xu, Debbie Payne-Turner, Hiroki Yoshihara, Mignon L Loh, John Horan,[...]. Nature 2018
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PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia.
Zhaohui Gu, Michelle L Churchman, Kathryn G Roberts, Ian Moore, Xin Zhou, Joy Nakitandwe, Kohei Hagiwara, Stephane Pelletier, Sebastien Gingras, Hartmut Berns,[...]. Nat Genet 2019
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Improved Survival for Children and Young Adults With T-Lineage Acute Lymphoblastic Leukemia: Results From the Children's Oncology Group AALL0434 Methotrexate Randomization.
Stuart S Winter, Kimberly P Dunsmore, Meenakshi Devidas, Brent L Wood, Natia Esiashvili, Zhiguo Chen, Nancy Eisenberg, Nikki Briegel, Robert J Hayashi, Julie M Gastier-Foster,[...]. J Clin Oncol 2018
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The genetics and molecular biology of T-ALL.
Tiziana Girardi, Carmen Vicente, Jan Cools, Kim De Keersmaecker. Blood 2017
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Targeted sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia.
Carmen Vicente, Claire Schwab, Michaël Broux, Ellen Geerdens, Sandrine Degryse, Sofie Demeyer, Idoya Lahortiga, Alannah Elliott, Lucy Chilton, Roberta La Starza,[...]. Haematologica 2015
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ETV6 mutations in early immature human T cell leukemias.
Pieter Van Vlierberghe, Alberto Ambesi-Impiombato, Arianne Perez-Garcia, J Erika Haydu, Isaura Rigo, Michael Hadler, Valeria Tosello, Giusy Della Gatta, Elisabeth Paietta, Janis Racevskis,[...]. J Exp Med 2011
Pieter Van Vlierberghe, Alberto Ambesi-Impiombato, Arianne Perez-Garcia, J Erika Haydu, Isaura Rigo, Michael Hadler, Valeria Tosello, Giusy Della Gatta, Elisabeth Paietta, Janis Racevskis,[...]. J Exp Med 2011
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HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL).
Jean Soulier, Emmanuelle Clappier, Jean-Michel Cayuela, Armelle Regnault, Marina García-Peydró, Hervé Dombret, André Baruchel, Maria-Luisa Toribio, François Sigaux. Blood 2005
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A pediatric regimen for older adolescents and young adults with acute lymphoblastic leukemia: results of CALGB 10403.
Wendy Stock, Selina M Luger, Anjali S Advani, Jun Yin, Richard C Harvey, Charles G Mullighan, Cheryl L Willman, Noreen Fulton, Kristina M Laumann, Greg Malnassy,[...]. Blood 2019
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An early thymic precursor phenotype predicts outcome exclusively in HOXA-overexpressing adult T-cell acute lymphoblastic leukemia: a Group for Research in Adult Acute Lymphoblastic Leukemia study.
Jonathan Bond, Tony Marchand, Aurore Touzart, Agata Cieslak, Amélie Trinquand, Laurent Sutton, Isabelle Radford-Weiss, Ludovic Lhermitte, Salvatore Spicuglia, Hervé Dombret,[...]. Haematologica 2016
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Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study.
Martin Schrappe, Maria Grazia Valsecchi, Claus R Bartram, André Schrauder, Renate Panzer-Grümayer, Anja Möricke, Rosanna Parasole, Martin Zimmermann, Michael Dworzak, Barbara Buldini,[...]. Blood 2011
Martin Schrappe, Maria Grazia Valsecchi, Claus R Bartram, André Schrauder, Renate Panzer-Grümayer, Anja Möricke, Rosanna Parasole, Martin Zimmermann, Michael Dworzak, Barbara Buldini,[...]. Blood 2011
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Children's Oncology Group AALL0434: A Phase III Randomized Clinical Trial Testing Nelarabine in Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia.
Kimberly P Dunsmore, Stuart S Winter, Meenakshi Devidas, Brent L Wood, Natia Esiashvili, Zhiguo Chen, Nancy Eisenberg, Nikki Briegel, Robert J Hayashi, Julie M Gastier-Foster,[...]. J Clin Oncol 2020
Kimberly P Dunsmore, Stuart S Winter, Meenakshi Devidas, Brent L Wood, Natia Esiashvili, Zhiguo Chen, Nancy Eisenberg, Nikki Briegel, Robert J Hayashi, Julie M Gastier-Foster,[...]. J Clin Oncol 2020
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Oncogenetics and minimal residual disease are independent outcome predictors in adult patients with acute lymphoblastic leukemia.
Kheira Beldjord, Sylvie Chevret, Vahid Asnafi, Françoise Huguet, Marie-Laure Boulland, Thibaut Leguay, Xavier Thomas, Jean-Michel Cayuela, Nathalie Grardel, Yves Chalandon,[...]. Blood 2014
Kheira Beldjord, Sylvie Chevret, Vahid Asnafi, Françoise Huguet, Marie-Laure Boulland, Thibaut Leguay, Xavier Thomas, Jean-Michel Cayuela, Nathalie Grardel, Yves Chalandon,[...]. Blood 2014
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Clinical Experience With Venetoclax Combined With Chemotherapy for Relapsed or Refractory T-Cell Acute Lymphoblastic Leukemia.
Guillaume Richard-Carpentier, Elias Jabbour, Nicholas J Short, Caitlin R Rausch, Jonathan M Savoy, Prithviraj Bose, Musa Yilmaz, Nitin Jain, Gautam Borthakur, Maro Ohanian,[...]. Clin Lymphoma Myeloma Leuk 2020
Guillaume Richard-Carpentier, Elias Jabbour, Nicholas J Short, Caitlin R Rausch, Jonathan M Savoy, Prithviraj Bose, Musa Yilmaz, Nitin Jain, Gautam Borthakur, Maro Ohanian,[...]. Clin Lymphoma Myeloma Leuk 2020
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Unique clinico-biological, genetic and prognostic features of adult early T-cell precursor acute lymphoblastic leukemia.
Eulàlia Genescà, Mireia Morgades, Pau Montesinos, Pere Barba, Cristina Gil, Ramon Guàrdia, María-José Moreno, Daniel Martínez-Carballeira, Irene García-Cadenas, Susana Vives,[...]. Haematologica 2020
Eulàlia Genescà, Mireia Morgades, Pau Montesinos, Pere Barba, Cristina Gil, Ramon Guàrdia, María-José Moreno, Daniel Martínez-Carballeira, Irene García-Cadenas, Susana Vives,[...]. Haematologica 2020
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Early T-cell precursor acute lymphoblastic leukaemia in children treated in AIEOP centres with AIEOP-BFM protocols: a retrospective analysis.
Valentino Conter, Maria Grazia Valsecchi, Barbara Buldini, Rosanna Parasole, Franco Locatelli, Antonella Colombini, Carmelo Rizzari, Maria Caterina Putti, Elena Barisone, Luca Lo Nigro,[...]. Lancet Haematol 2016
Valentino Conter, Maria Grazia Valsecchi, Barbara Buldini, Rosanna Parasole, Franco Locatelli, Antonella Colombini, Carmelo Rizzari, Maria Caterina Putti, Elena Barisone, Luca Lo Nigro,[...]. Lancet Haematol 2016
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FLT3 mutations in early T-cell precursor ALL characterize a stem cell like leukemia and imply the clinical use of tyrosine kinase inhibitors.
Martin Neumann, Ebru Coskun, Lars Fransecky, Liliana H Mochmann, Isabelle Bartram, Nasrin Farhadi Sartangi, Sandra Heesch, Nicola Gökbuget, Stefan Schwartz, Christian Brandts,[...]. PLoS One 2013
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A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study.
Monique L Den Boer, Marjon van Slegtenhorst, Renée X De Menezes, Meyling H Cheok, Jessica G C A M Buijs-Gladdines, Susan T C J M Peters, Laura J C M Van Zutven, H Berna Beverloo, Peter J Van der Spek, Gaby Escherich,[...]. Lancet Oncol 2009
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ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia.
Sofie Peirs, Filip Matthijssens, Steven Goossens, Inge Van de Walle, Katia Ruggero, Charles E de Bock, Sandrine Degryse, Kirsten Canté-Barrett, Delphine Briot, Emmanuelle Clappier,[...]. Blood 2014
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Prognostic relevance of integrated genetic profiling in adult T-cell acute lymphoblastic leukemia.
Pieter Van Vlierberghe, Alberto Ambesi-Impiombato, Kim De Keersmaecker, Michael Hadler, Elisabeth Paietta, Martin S Tallman, Jacob M Rowe, Carles Forne, Montserrat Rue, Adolfo A Ferrando. Blood 2013
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Immature MEF2C-dysregulated T-cell leukemia patients have an early T-cell precursor acute lymphoblastic leukemia gene signature and typically have non-rearranged T-cell receptors.
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Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia.
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Pediatric-inspired therapy in adults with Philadelphia chromosome-negative acute lymphoblastic leukemia: the GRAALL-2003 study.
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The molecular profile of adult T-cell acute lymphoblastic leukemia: mutations in RUNX1 and DNMT3A are associated with poor prognosis in T-ALL.
Vera Grossmann, Claudia Haferlach, Sandra Weissmann, Andreas Roller, Sonja Schindela, Franziska Poetzinger, Kathrin Stadler, Frauke Bellos, Wolfgang Kern, Torsten Haferlach,[...]. Genes Chromosomes Cancer 2013
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Long-term outcome of a pediatric-inspired regimen used for adults aged 18-50 years with newly diagnosed acute lymphoblastic leukemia.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.