Sokol V Todi, Brett J Winborn, K Matthew Scaglione, Jessica R Blount, Sue M Travis, Henry L Paulson. EMBO J 2009
Times Cited: 124
Times Cited: 124
Times Cited
Times Co-cited
Similarity
The deubiquitinating enzyme ataxin-3, a polyglutamine disease protein, edits Lys63 linkages in mixed linkage ubiquitin chains.
Brett J Winborn, Sue M Travis, Sokol V Todi, K Matthew Scaglione, Ping Xu, Aislinn J Williams, Robert E Cohen, Junmin Peng, Henry L Paulson. J Biol Chem 2008
Brett J Winborn, Sue M Travis, Sokol V Todi, K Matthew Scaglione, Ping Xu, Aislinn J Williams, Robert E Cohen, Junmin Peng, Henry L Paulson. J Biol Chem 2008
55
Activity and cellular functions of the deubiquitinating enzyme and polyglutamine disease protein ataxin-3 are regulated by ubiquitination at lysine 117.
Sokol V Todi, K Matthew Scaglione, Jessica R Blount, Venkatesha Basrur, Kevin P Conlon, Annalisa Pastore, Kojo Elenitoba-Johnson, Henry L Paulson. J Biol Chem 2010
Sokol V Todi, K Matthew Scaglione, Jessica R Blount, Venkatesha Basrur, Kevin P Conlon, Annalisa Pastore, Kojo Elenitoba-Johnson, Henry L Paulson. J Biol Chem 2010
60
The polyglutamine neurodegenerative protein ataxin-3 binds polyubiquitylated proteins and has ubiquitin protease activity.
Barrington Burnett, Fusheng Li, Randall N Pittman. Hum Mol Genet 2003
Barrington Burnett, Fusheng Li, Randall N Pittman. Hum Mol Genet 2003
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Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP.
K Matthew Scaglione, Eszter Zavodszky, Sokol V Todi, Srikanth Patury, Ping Xu, Edgardo Rodríguez-Lebrón, Svetlana Fischer, John Konen, Ana Djarmati, Junmin Peng,[...]. Mol Cell 2011
K Matthew Scaglione, Eszter Zavodszky, Sokol V Todi, Srikanth Patury, Ping Xu, Edgardo Rodríguez-Lebrón, Svetlana Fischer, John Konen, Ana Djarmati, Junmin Peng,[...]. Mol Cell 2011
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Breaking the chains: structure and function of the deubiquitinases.
David Komander, Michael J Clague, Sylvie Urbé. Nat Rev Mol Cell Biol 2009
David Komander, Michael J Clague, Sylvie Urbé. Nat Rev Mol Cell Biol 2009
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Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes.
Francisca E Reyes-Turcu, Karen H Ventii, Keith D Wilkinson. Annu Rev Biochem 2009
Francisca E Reyes-Turcu, Karen H Ventii, Keith D Wilkinson. Annu Rev Biochem 2009
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Ataxin-3 binds VCP/p97 and regulates retrotranslocation of ERAD substrates.
Xiaoyan Zhong, Randall N Pittman. Hum Mol Genet 2006
Xiaoyan Zhong, Randall N Pittman. Hum Mol Genet 2006
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CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1.
Y Kawaguchi, T Okamoto, M Taniwaki, M Aizawa, M Inoue, S Katayama, H Kawakami, S Nakamura, M Nishimura, I Akiguchi. Nat Genet 1994
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Toward understanding Machado-Joseph disease.
Maria do Carmo Costa, Henry L Paulson. Prog Neurobiol 2012
Maria do Carmo Costa, Henry L Paulson. Prog Neurobiol 2012
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The Machado-Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability.
Thomas M Durcan, Maria Kontogiannea, Thorhildur Thorarinsdottir, Lara Fallon, Aislinn J Williams, Ana Djarmati, Tadeu Fantaneanu, Henry L Paulson, Edward A Fon. Hum Mol Genet 2011
Thomas M Durcan, Maria Kontogiannea, Thorhildur Thorarinsdottir, Lara Fallon, Aislinn J Williams, Ana Djarmati, Tadeu Fantaneanu, Henry L Paulson, Edward A Fon. Hum Mol Genet 2011
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Defining the human deubiquitinating enzyme interaction landscape.
Mathew E Sowa, Eric J Bennett, Steven P Gygi, J Wade Harper. Cell 2009
Mathew E Sowa, Eric J Bennett, Steven P Gygi, J Wade Harper. Cell 2009
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Ataxin-3 suppresses polyglutamine neurodegeneration in Drosophila by a ubiquitin-associated mechanism.
John M Warrick, Lance M Morabito, Julide Bilen, Beth Gordesky-Gold, Lynn Z Faust, Henry L Paulson, Nancy M Bonini. Mol Cell 2005
John M Warrick, Lance M Morabito, Julide Bilen, Beth Gordesky-Gold, Lynn Z Faust, Henry L Paulson, Nancy M Bonini. Mol Cell 2005
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Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3.
H L Paulson, M K Perez, Y Trottier, J Q Trojanowski, S H Subramony, S S Das, P Vig, J L Mandel, K H Fischbeck, R N Pittman. Neuron 1997
H L Paulson, M K Perez, Y Trottier, J Q Trojanowski, S H Subramony, S S Das, P Vig, J L Mandel, K H Fischbeck, R N Pittman. Neuron 1997
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Ataxin-3 interactions with rad23 and valosin-containing protein and its associations with ubiquitin chains and the proteasome are consistent with a role in ubiquitin-mediated proteolysis.
Ellen W Doss-Pepe, Edward S Stenroos, William G Johnson, Kiran Madura. Mol Cell Biol 2003
Ellen W Doss-Pepe, Edward S Stenroos, William G Johnson, Kiran Madura. Mol Cell Biol 2003
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An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis.
Annett Boeddrich, Sébastien Gaumer, Annette Haacke, Nikolay Tzvetkov, Mario Albrecht, Bernd O Evert, Eva C Müller, Rudi Lurz, Peter Breuer, Nancy Schugardt,[...]. EMBO J 2006
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22
Ataxin-3 represses transcription via chromatin binding, interaction with histone deacetylase 3, and histone deacetylation.
Bernd O Evert, Julieta Araujo, Ana M Vieira-Saecker, Rob A I de Vos, Sigrid Harendza, Thomas Klockgether, Ullrich Wüllner. J Neurosci 2006
Bernd O Evert, Julieta Araujo, Ana M Vieira-Saecker, Rob A I de Vos, Sigrid Harendza, Thomas Klockgether, Ullrich Wüllner. J Neurosci 2006
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The polyglutamine neurodegenerative protein ataxin 3 regulates aggresome formation.
Barrington G Burnett, Randall N Pittman. Proc Natl Acad Sci U S A 2005
Barrington G Burnett, Randall N Pittman. Proc Natl Acad Sci U S A 2005
22
A genomic and functional inventory of deubiquitinating enzymes.
Sebastian M B Nijman, Mark P A Luna-Vargas, Arno Velds, Thijn R Brummelkamp, Annette M G Dirac, Titia K Sixma, René Bernards. Cell 2005
Sebastian M B Nijman, Mark P A Luna-Vargas, Arno Velds, Thijn R Brummelkamp, Annette M G Dirac, Titia K Sixma, René Bernards. Cell 2005
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Inactivation of the mouse Atxn3 (ataxin-3) gene increases protein ubiquitination.
Ina Schmitt, Marion Linden, Hassan Khazneh, Bernd O Evert, Peter Breuer, Thomas Klockgether, Ullrich Wuellner. Biochem Biophys Res Commun 2007
Ina Schmitt, Marion Linden, Hassan Khazneh, Bernd O Evert, Peter Breuer, Thomas Klockgether, Ullrich Wuellner. Biochem Biophys Res Commun 2007
22
The solution structure of the Josephin domain of ataxin-3: structural determinants for molecular recognition.
Giuseppe Nicastro, Rajesh P Menon, Laura Masino, Philip P Knowles, Neil Q McDonald, Annalisa Pastore. Proc Natl Acad Sci U S A 2005
Giuseppe Nicastro, Rajesh P Menon, Laura Masino, Philip P Knowles, Neil Q McDonald, Annalisa Pastore. Proc Natl Acad Sci U S A 2005
21
Josephin domain of ataxin-3 contains two distinct ubiquitin-binding sites.
Giuseppe Nicastro, Laura Masino, Veronica Esposito, Rajesh P Menon, Alfonso De Simone, Franca Fraternali, Annalisa Pastore. Biopolymers 2009
Giuseppe Nicastro, Laura Masino, Veronica Esposito, Rajesh P Menon, Alfonso De Simone, Franca Fraternali, Annalisa Pastore. Biopolymers 2009
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Defining the role of ubiquitin-interacting motifs in the polyglutamine disease protein, ataxin-3.
Sarah J Shoesmith Berke, Yaohui Chai, Ginger L Marrs, Hsiang Wen, Henry L Paulson. J Biol Chem 2005
Sarah J Shoesmith Berke, Yaohui Chai, Ginger L Marrs, Hsiang Wen, Henry L Paulson. J Biol Chem 2005
27
Regulation of retrotranslocation by p97-associated deubiquitinating enzyme ataxin-3.
Qiuyan Wang, Lianyun Li, Yihong Ye. J Cell Biol 2006
Qiuyan Wang, Lianyun Li, Yihong Ye. J Cell Biol 2006
21
Co-chaperone CHIP associates with expanded polyglutamine protein and promotes their degradation by proteasomes.
Nihar Ranjan Jana, Priyanka Dikshit, Anand Goswami, Svetlana Kotliarova, Shigeo Murata, Keiji Tanaka, Nobuyuki Nukina. J Biol Chem 2005
Nihar Ranjan Jana, Priyanka Dikshit, Anand Goswami, Svetlana Kotliarova, Shigeo Murata, Keiji Tanaka, Nobuyuki Nukina. J Biol Chem 2005
20
Polyglutamine diseases: the special case of ataxin-3 and Machado-Joseph disease.
Carlos A Matos, Sandra de Macedo-Ribeiro, Ana Luísa Carvalho. Prog Neurobiol 2011
Carlos A Matos, Sandra de Macedo-Ribeiro, Ana Luísa Carvalho. Prog Neurobiol 2011
21
Ubiquitination regulates the neuroprotective function of the deubiquitinase ataxin-3 in vivo.
Wei-Ling Tsou, Aaron A Burr, Michelle Ouyang, Jessica R Blount, K Matthew Scaglione, Sokol V Todi. J Biol Chem 2013
Wei-Ling Tsou, Aaron A Burr, Michelle Ouyang, Jessica R Blount, K Matthew Scaglione, Sokol V Todi. J Biol Chem 2013
58
Understanding the role of the Josephin domain in the PolyUb binding and cleavage properties of ataxin-3.
Giuseppe Nicastro, Sokol V Todi, Ezgi Karaca, Alexandre M J J Bonvin, Henry L Paulson, Annalisa Pastore. PLoS One 2010
Giuseppe Nicastro, Sokol V Todi, Ezgi Karaca, Alexandre M J J Bonvin, Henry L Paulson, Annalisa Pastore. PLoS One 2010
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Ubiquitin-binding site 2 of ataxin-3 prevents its proteasomal degradation by interacting with Rad23.
Jessica R Blount, Wei-Ling Tsou, Gorica Ristic, Aaron A Burr, Michelle Ouyang, Holland Galante, K Matthew Scaglione, Sokol V Todi. Nat Commun 2014
Jessica R Blount, Wei-Ling Tsou, Gorica Ristic, Aaron A Burr, Michelle Ouyang, Holland Galante, K Matthew Scaglione, Sokol V Todi. Nat Commun 2014
44
Deubiquitinating function of ataxin-3: insights from the solution structure of the Josephin domain.
Yuxin Mao, Francesca Senic-Matuglia, Pier Paolo Di Fiore, Simona Polo, Michael E Hodsdon, Pietro De Camilli. Proc Natl Acad Sci U S A 2005
Yuxin Mao, Francesca Senic-Matuglia, Pier Paolo Di Fiore, Simona Polo, Michael E Hodsdon, Pietro De Camilli. Proc Natl Acad Sci U S A 2005
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Machado-Joseph disease gene product is a cytoplasmic protein widely expressed in brain.
H L Paulson, S S Das, P B Crino, M K Perez, S C Patel, D Gotsdiner, K H Fischbeck, R N Pittman. Ann Neurol 1997
H L Paulson, S S Das, P B Crino, M K Perez, S C Patel, D Gotsdiner, K H Fischbeck, R N Pittman. Ann Neurol 1997
18
CK2-dependent phosphorylation determines cellular localization and stability of ataxin-3.
Thorsten Mueller, Peter Breuer, Ina Schmitt, Jochen Walter, Bernd O Evert, Ullrich Wüllner. Hum Mol Genet 2009
Thorsten Mueller, Peter Breuer, Ina Schmitt, Jochen Walter, Bernd O Evert, Ullrich Wüllner. Hum Mol Genet 2009
26
Ataxin-3 is a histone-binding protein with two independent transcriptional corepressor activities.
Fusheng Li, Todd Macfarlan, Randall N Pittman, Debabrata Chakravarti. J Biol Chem 2002
Fusheng Li, Todd Macfarlan, Randall N Pittman, Debabrata Chakravarti. J Biol Chem 2002
17
Molecular clearance of ataxin-3 is regulated by a mammalian E4.
Masaki Matsumoto, Masayoshi Yada, Shigetsugu Hatakeyama, Hiroshi Ishimoto, Teiichi Tanimura, Shoji Tsuji, Akira Kakizuka, Masatoshi Kitagawa, Keiichi I Nakayama. EMBO J 2004
Masaki Matsumoto, Masayoshi Yada, Shigetsugu Hatakeyama, Hiroshi Ishimoto, Teiichi Tanimura, Shoji Tsuji, Akira Kakizuka, Masatoshi Kitagawa, Keiichi I Nakayama. EMBO J 2004
17
Ataxin-3, the MJD1 gene product, interacts with the two human homologs of yeast DNA repair protein RAD23, HHR23A and HHR23B.
G Wang, N Sawai, S Kotliarova, I Kanazawa, N Nukina. Hum Mol Genet 2000
G Wang, N Sawai, S Kotliarova, I Kanazawa, N Nukina. Hum Mol Genet 2000
16
Cellular turnover of the polyglutamine disease protein ataxin-3 is regulated by its catalytic activity.
Sokol V Todi, Mario N Laco, Brett J Winborn, Sue M Travis, Hsiang M Wen, Henry L Paulson. J Biol Chem 2007
Sokol V Todi, Mario N Laco, Brett J Winborn, Sue M Travis, Hsiang M Wen, Henry L Paulson. J Biol Chem 2007
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Deubiquitylases from genes to organism.
Michael J Clague, Igor Barsukov, Judy M Coulson, Han Liu, Daniel J Rigden, Sylvie Urbé. Physiol Rev 2013
Michael J Clague, Igor Barsukov, Judy M Coulson, Han Liu, Daniel J Rigden, Sylvie Urbé. Physiol Rev 2013
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Domain architecture of the polyglutamine protein ataxin-3: a globular domain followed by a flexible tail.
Laura Masino, Valeria Musi, Rajesh P Menon, Paola Fusi, Geoff Kelly, Thomas A Frenkiel, Yvon Trottier, Annalisa Pastore. FEBS Lett 2003
Laura Masino, Valeria Musi, Rajesh P Menon, Paola Fusi, Geoff Kelly, Thomas A Frenkiel, Yvon Trottier, Annalisa Pastore. FEBS Lett 2003
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Poly-ubiquitin binding by the polyglutamine disease protein ataxin-3 links its normal function to protein surveillance pathways.
Yaohui Chai, Sarah Shoesmith Berke, Robert E Cohen, Henry L Paulson. J Biol Chem 2004
Yaohui Chai, Sarah Shoesmith Berke, Robert E Cohen, Henry L Paulson. J Biol Chem 2004
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Mechanism and consequences for paralog-specific sumoylation of ubiquitin-specific protease 25.
Erik Meulmeester, Marion Kunze, He Hsuan Hsiao, Henning Urlaub, Frauke Melchior. Mol Cell 2008
Erik Meulmeester, Marion Kunze, He Hsuan Hsiao, Henning Urlaub, Frauke Melchior. Mol Cell 2008
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An isoform of ataxin-3 accumulates in the nucleus of neuronal cells in affected brain regions of SCA3 patients.
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Nuclear localization of ataxin-3 is required for the manifestation of symptoms in SCA3: in vivo evidence.
Ulrike Bichelmeier, Thorsten Schmidt, Jeannette Hübener, Jana Boy, Lukas Rüttiger, Karina Häbig, Sven Poths, Michael Bonin, Marlies Knipper, Werner J Schmidt,[...]. J Neurosci 2007
Ulrike Bichelmeier, Thorsten Schmidt, Jeannette Hübener, Jana Boy, Lukas Rüttiger, Karina Häbig, Sven Poths, Michael Bonin, Marlies Knipper, Werner J Schmidt,[...]. J Neurosci 2007
15
Splice isoforms of the polyglutamine disease protein ataxin-3 exhibit similar enzymatic yet different aggregation properties.
Ginny Marie Harris, Katerina Dodelzon, Lijie Gong, Pedro Gonzalez-Alegre, Henry L Paulson. PLoS One 2010
Ginny Marie Harris, Katerina Dodelzon, Lijie Gong, Pedro Gonzalez-Alegre, Henry L Paulson. PLoS One 2010
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Interaction of the polyglutamine protein ataxin-3 with Rad23 regulates toxicity in Drosophila models of Spinocerebellar Ataxia Type 3.
Joanna R Sutton, Jessica R Blount, Kozeta Libohova, Wei-Ling Tsou, Gnanada S Joshi, Henry L Paulson, Maria do Carmo Costa, K Matthew Scaglione, Sokol V Todi. Hum Mol Genet 2017
Joanna R Sutton, Jessica R Blount, Kozeta Libohova, Wei-Ling Tsou, Gnanada S Joshi, Henry L Paulson, Maria do Carmo Costa, K Matthew Scaglione, Sokol V Todi. Hum Mol Genet 2017
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The two-stage pathway of ataxin-3 fibrillogenesis involves a polyglutamine-independent step.
Andrew M Ellisdon, Bronwen Thomas, Stephen P Bottomley. J Biol Chem 2006
Andrew M Ellisdon, Bronwen Thomas, Stephen P Bottomley. J Biol Chem 2006
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Enhancement of proteasome activity by a small-molecule inhibitor of USP14.
Byung-Hoon Lee, Min Jae Lee, Soyeon Park, Dong-Chan Oh, Suzanne Elsasser, Ping-Chung Chen, Carlos Gartner, Nevena Dimova, John Hanna, Steven P Gygi,[...]. Nature 2010
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14
Balancing act: deubiquitinating enzymes in the nervous system.
Sokol V Todi, Henry L Paulson. Trends Neurosci 2011
Sokol V Todi, Henry L Paulson. Trends Neurosci 2011
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Phosphorylation of ataxin-3 by glycogen synthase kinase 3beta at serine 256 regulates the aggregation of ataxin-3.
Erkang Fei, Nali Jia, Tao Zhang, Xiaochuan Ma, Hongfeng Wang, Chao Liu, Wei Zhang, Lili Ding, Nobuyuki Nukina, Guanghui Wang. Biochem Biophys Res Commun 2007
Erkang Fei, Nali Jia, Tao Zhang, Xiaochuan Ma, Hongfeng Wang, Chao Liu, Wei Zhang, Lili Ding, Nobuyuki Nukina, Guanghui Wang. Biochem Biophys Res Commun 2007
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Proteotoxic stress increases nuclear localization of ataxin-3.
Christopher P Reina, Xiaoyan Zhong, Randall N Pittman. Hum Mol Genet 2010
Christopher P Reina, Xiaoyan Zhong, Randall N Pittman. Hum Mol Genet 2010
22
Characterization of the structure and the amyloidogenic properties of the Josephin domain of the polyglutamine-containing protein ataxin-3.
Laura Masino, Giuseppe Nicastro, Rajesh P Menon, Fabrizio Dal Piaz, Lesley Calder, Annalisa Pastore. J Mol Biol 2004
Laura Masino, Giuseppe Nicastro, Rajesh P Menon, Fabrizio Dal Piaz, Lesley Calder, Annalisa Pastore. J Mol Biol 2004
13
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.