A citation-based method for searching scientific literature

Veit Hornung, Andrea Ablasser, Marie Charrel-Dennis, Franz Bauernfeind, Gabor Horvath, Daniel R Caffrey, Eicke Latz, Katherine A Fitzgerald. Nature 2009
Times Cited: 1524







List of co-cited articles
1258 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA.
Teresa Fernandes-Alnemri, Je-Wook Yu, Pinaki Datta, Jianghong Wu, Emad S Alnemri. Nature 2009
38

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Jianjin Shi, Yue Zhao, Kun Wang, Xuyan Shi, Yue Wang, Huanwei Huang, Yinghua Zhuang, Tao Cai, Fengchao Wang, Feng Shao. Nature 2015
23

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses.
Vijay A K Rathinam, Zhaozhao Jiang, Stephen N Waggoner, Shruti Sharma, Leah E Cole, Lisa Waggoner, Sivapriya Kailasan Vanaja, Brian G Monks, Sandhya Ganesan, Eicke Latz,[...]. Nat Immunol 2010
870
20


The inflammasomes.
Kate Schroder, Jurg Tschopp. Cell 2010
17

IFI16 is an innate immune sensor for intracellular DNA.
Leonie Unterholzner, Sinead E Keating, Marcin Baran, Kristy A Horan, Søren B Jensen, Shruti Sharma, Cherilyn M Sirois, Tengchuan Jin, Eicke Latz, T Sam Xiao,[...]. Nat Immunol 2010
17

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.
Xing Liu, Zhibin Zhang, Jianbin Ruan, Youdong Pan, Venkat Giri Magupalli, Hao Wu, Judy Lieberman. Nature 2016
979
17

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.
Lijun Sun, Jiaxi Wu, Fenghe Du, Xiang Chen, Zhijian J Chen. Science 2013
17

Inflammatory caspases are innate immune receptors for intracellular LPS.
Jianjin Shi, Yue Zhao, Yupeng Wang, Wenqing Gao, Jingjin Ding, Peng Li, Liyan Hu, Feng Shao. Nature 2014
967
16

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
Nobuhiko Kayagaki, Irma B Stowe, Bettina L Lee, Karen O'Rourke, Keith Anderson, Søren Warming, Trinna Cuellar, Benjamin Haley, Merone Roose-Girma, Qui T Phung,[...]. Nature 2015
16

HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA.
Tara L Roberts, Adi Idris, Jasmyn A Dunn, Greg M Kelly, Carol M Burnton, Samantha Hodgson, Lani L Hardy, Valerie Garceau, Matthew J Sweet, Ian L Ross,[...]. Science 2009
594
16

Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor.
Tengchuan Jin, Andrew Perry, Jiansheng Jiang, Patrick Smith, James A Curry, Leonie Unterholzner, Zhaozhao Jiang, Gabor Horvath, Vijay A Rathinam, Ricky W Johnstone,[...]. Immunity 2012
301
15

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome.
Tilmann Bürckstümmer, Christoph Baumann, Stephan Blüml, Evelyn Dixit, Gerhard Dürnberger, Hannah Jahn, Melanie Planyavsky, Martin Bilban, Jacques Colinge, Keiryn L Bennett,[...]. Nat Immunol 2009
721
15

Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death.
Jianjin Shi, Wenqing Gao, Feng Shao. Trends Biochem Sci 2017
707
14

Inflammasomes: mechanism of assembly, regulation and signalling.
Petr Broz, Vishva M Dixit. Nat Rev Immunol 2016
14

Mechanism and Regulation of NLRP3 Inflammasome Activation.
Yuan He, Hideki Hara, Gabriel Núñez. Trends Biochem Sci 2016
14

K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter.
Raúl Muñoz-Planillo, Peter Kuffa, Giovanny Martínez-Colón, Brenna L Smith, Thekkelnaycke M Rajendiran, Gabriel Núñez. Immunity 2013
988
14

Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
Franz G Bauernfeind, Gabor Horvath, Andrea Stutz, Emad S Alnemri, Kelly MacDonald, David Speert, Teresa Fernandes-Alnemri, Jianghong Wu, Brian G Monks, Katherine A Fitzgerald,[...]. J Immunol 2009
13

Non-canonical inflammasome activation targets caspase-11.
Nobuhiko Kayagaki, Søren Warming, Mohamed Lamkanfi, Lieselotte Vande Walle, Salina Louie, Jennifer Dong, Kim Newton, Yan Qu, Jinfeng Liu, Sherry Heldens,[...]. Nature 2011
13

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin.
Yupeng Wang, Wenqing Gao, Xuyan Shi, Jingjin Ding, Wang Liu, Huabin He, Kun Wang, Feng Shao. Nature 2017
623
12

Pore-forming activity and structural autoinhibition of the gasdermin family.
Jingjin Ding, Kun Wang, Wang Liu, Yang She, Qi Sun, Jianjin Shi, Hanzi Sun, Da-Cheng Wang, Feng Shao. Nature 2016
818
12

The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation.
Nathan Kelley, Devon Jeltema, Yanhui Duan, Yuan He. Int J Mol Sci 2019
508
12

Pathogen recognition and innate immunity.
Shizuo Akira, Satoshi Uematsu, Osamu Takeuchi. Cell 2006
12

Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes.
Alvin Lu, Venkat Giri Magupalli, Jianbin Ruan, Qian Yin, Maninjay K Atianand, Matthijn R Vos, Gunnar F Schröder, Katherine A Fitzgerald, Hao Wu, Edward H Egelman. Cell 2014
644
11

cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.
Andrea Ablasser, Marion Goldeck, Taner Cavlar, Tobias Deimling, Gregor Witte, Ingo Röhl, Karl-Peter Hopfner, Janos Ludwig, Veit Hornung. Nature 2013
713
11

Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects.
Xiao-Dong Li, Jiaxi Wu, Daxing Gao, Hua Wang, Lijun Sun, Zhijian J Chen. Science 2013
585
11

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Rebecca C Coll, Avril A B Robertson, Jae Jin Chae, Sarah C Higgins, Raúl Muñoz-Planillo, Marco C Inserra, Irina Vetter, Lara S Dungan, Brian G Monks, Andrea Stutz,[...]. Nat Med 2015
10

Mechanisms and functions of inflammasomes.
Mohamed Lamkanfi, Vishva M Dixit. Cell 2014
10

The NLRP3 inflammasome: molecular activation and regulation to therapeutics.
Karen V Swanson, Meng Deng, Jenny P-Y Ting. Nat Rev Immunol 2019
849
10

Pattern recognition receptors and inflammation.
Osamu Takeuchi, Shizuo Akira. Cell 2010
10



Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt.
Justin E Wilson, Alex S Petrucelli, Liang Chen, A Alicia Koblansky, Agnieszka D Truax, Yoshitaka Oyama, Arlin B Rogers, W June Brickey, Yuli Wang, Monika Schneider,[...]. Nat Med 2015
147
10

Gasdermin E suppresses tumour growth by activating anti-tumour immunity.
Zhibin Zhang, Ying Zhang, Shiyu Xia, Qing Kong, Shunying Li, Xing Liu, Caroline Junqueira, Karla F Meza-Sosa, Temy Mo Yin Mok, James Ansara,[...]. Nature 2020
178
10

Inflammasome Complexes: Emerging Mechanisms and Effector Functions.
Vijay A K Rathinam, Katherine A Fitzgerald. Cell 2016
371
10

Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA.
Jiaxi Wu, Lijun Sun, Xiang Chen, Fenghe Du, Heping Shi, Chuo Chen, Zhijian J Chen. Science 2013
10


Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome.
Hao Xu, Jieling Yang, Wenqing Gao, Lin Li, Peng Li, Li Zhang, Yi-Nan Gong, Xiaolan Peng, Jianzhong Jeff Xi, She Chen,[...]. Nature 2014
434
10


Inflammasomes: mechanism of action, role in disease, and therapeutics.
Haitao Guo, Justin B Callaway, Jenny P-Y Ting. Nat Med 2015
9

Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death.
Corey Rogers, Teresa Fernandes-Alnemri, Lindsey Mayes, Diana Alnemri, Gino Cingolani, Emad S Alnemri. Nat Commun 2017
405
9

Pyroptosis: host cell death and inflammation.
Tessa Bergsbaken, Susan L Fink, Brad T Cookson. Nat Rev Microbiol 2009
9

Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer.
Si Ming Man, Qifan Zhu, Liqin Zhu, Zhiping Liu, Rajendra Karki, Ankit Malik, Deepika Sharma, Liyuan Li, R K Subbarao Malireddi, Prajwal Gurung,[...]. Cell 2015
181
9

The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury.
Bo Hu, Chengcheng Jin, Hua-Bing Li, Jiyu Tong, Xinshou Ouyang, Naniye Malli Cetinbas, Shu Zhu, Till Strowig, Fred C Lam, Chen Zhao,[...]. Science 2016
152
9

IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes.
Jessica F Almine, Craig A J O'Hare, Gillian Dunphy, Ismar R Haga, Rangeetha J Naik, Abdelmadjid Atrih, Dympna J Connolly, Jordan Taylor, Ian R Kelsall, Andrew G Bowie,[...]. Nat Commun 2017
158
9

Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells.
Zhiwei Zhou, Huabin He, Kun Wang, Xuyan Shi, Yupeng Wang, Ya Su, Yao Wang, Da Li, Wang Liu, Yongliang Zhang,[...]. Science 2020
146
9

The AIM2 inflammasome: Sensor of pathogens and cellular perturbations.
Jérôme Lugrin, Fabio Martinon. Immunol Rev 2018
131
9

Noncanonical inflammasome activation by intracellular LPS independent of TLR4.
Nobuhiko Kayagaki, Michael T Wong, Irma B Stowe, Sree Ranjani Ramani, Lino C Gonzalez, Sachiko Akashi-Takamura, Kensuke Miyake, Juan Zhang, Wyne P Lee, Artur Muszyński,[...]. Science 2013
836
9

Assembly-driven activation of the AIM2 foreign-dsDNA sensor provides a polymerization template for downstream ASC.
Seamus R Morrone, Mariusz Matyszewski, Xiong Yu, Michael Delannoy, Edward H Egelman, Jungsan Sohn. Nat Commun 2015
77
11

Gout-associated uric acid crystals activate the NALP3 inflammasome.
Fabio Martinon, Virginie Pétrilli, Annick Mayor, Aubry Tardivel, Jürg Tschopp. Nature 2006
9


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.