Ilya Bezprozvanny. Trends Mol Med 2009
Times Cited: 288
Times Cited: 288
Times Cited
Times Co-cited
Similarity
Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease.
Ilya Bezprozvanny, Mark P Mattson. Trends Neurosci 2008
Ilya Bezprozvanny, Mark P Mattson. Trends Neurosci 2008
20
Calcium Hypothesis of Alzheimer's disease and brain aging: A framework for integrating new evidence into a comprehensive theory of pathogenesis.
. Alzheimers Dement 2017
. Alzheimers Dement 2017
11
Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations.
Huiping Tu, Omar Nelson, Arseny Bezprozvanny, Zhengnan Wang, Sheu-Fen Lee, Yi-Heng Hao, Lutgarde Serneels, Bart De Strooper, Gang Yu, Ilya Bezprozvanny. Cell 2006
Huiping Tu, Omar Nelson, Arseny Bezprozvanny, Zhengnan Wang, Sheu-Fen Lee, Yi-Heng Hao, Lutgarde Serneels, Bart De Strooper, Gang Yu, Ilya Bezprozvanny. Cell 2006
11
The versatility and universality of calcium signalling.
M J Berridge, P Lipp, M D Bootman. Nat Rev Mol Cell Biol 2000
M J Berridge, P Lipp, M D Bootman. Nat Rev Mol Cell Biol 2000
11
Reduced synaptic STIM2 expression and impaired store-operated calcium entry cause destabilization of mature spines in mutant presenilin mice.
Suya Sun, Hua Zhang, Jie Liu, Elena Popugaeva, Nan-Jie Xu, Stefan Feske, Charles L White, Ilya Bezprozvanny. Neuron 2014
Suya Sun, Hua Zhang, Jie Liu, Elena Popugaeva, Nan-Jie Xu, Stefan Feske, Charles L White, Ilya Bezprozvanny. Neuron 2014
10
Mechanism of Ca2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating.
King-Ho Cheung, Diana Shineman, Marioly Müller, César Cárdenas, Lijuan Mei, Jun Yang, Taisuke Tomita, Takeshi Iwatsubo, Virginia M-Y Lee, J Kevin Foskett. Neuron 2008
King-Ho Cheung, Diana Shineman, Marioly Müller, César Cárdenas, Lijuan Mei, Jun Yang, Taisuke Tomita, Takeshi Iwatsubo, Virginia M-Y Lee, J Kevin Foskett. Neuron 2008
10
Enhanced Store-Operated Calcium Entry Leads to Striatal Synaptic Loss in a Huntington's Disease Mouse Model.
Jun Wu, Daniel A Ryskamp, Xia Liang, Polina Egorova, Olga Zakharova, Gene Hung, Ilya Bezprozvanny. J Neurosci 2016
Jun Wu, Daniel A Ryskamp, Xia Liang, Polina Egorova, Olga Zakharova, Gene Hung, Ilya Bezprozvanny. J Neurosci 2016
11
Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons.
S L Chan, M Mayne, C P Holden, J D Geiger, M P Mattson. J Biol Chem 2000
S L Chan, M Mayne, C P Holden, J D Geiger, M P Mattson. J Biol Chem 2000
10
Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1.
Tie-Shan Tang, Huiping Tu, Edmond Y W Chan, Anton Maximov, Zhengnan Wang, Cheryl L Wellington, Michael R Hayden, Ilya Bezprozvanny. Neuron 2003
Tie-Shan Tang, Huiping Tu, Edmond Y W Chan, Anton Maximov, Zhengnan Wang, Cheryl L Wellington, Michael R Hayden, Ilya Bezprozvanny. Neuron 2003
9
Calcium signaling and molecular mechanisms underlying neurodegenerative diseases.
Ekaterina Pchitskaya, Elena Popugaeva, Ilya Bezprozvanny. Cell Calcium 2018
Ekaterina Pchitskaya, Elena Popugaeva, Ilya Bezprozvanny. Cell Calcium 2018
9
Dysregulation of neuronal calcium homeostasis in Alzheimer's disease - A therapeutic opportunity?
Elena Popugaeva, Ekaterina Pchitskaya, Ilya Bezprozvanny. Biochem Biophys Res Commun 2017
Elena Popugaeva, Ekaterina Pchitskaya, Ilya Bezprozvanny. Biochem Biophys Res Commun 2017
8
Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease.
Tie-Shan Tang, Elizabeth Slow, Vitalie Lupu, Irina G Stavrovskaya, Mutsuyuki Sugimori, Rodolfo Llinás, Bruce S Kristal, Michael R Hayden, Ilya Bezprozvanny. Proc Natl Acad Sci U S A 2005
Tie-Shan Tang, Elizabeth Slow, Vitalie Lupu, Irina G Stavrovskaya, Mutsuyuki Sugimori, Rodolfo Llinás, Bruce S Kristal, Michael R Hayden, Ilya Bezprozvanny. Proc Natl Acad Sci U S A 2005
8
Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult, and aged Alzheimer's disease mice.
Grace E Stutzmann, Ian Smith, Antonella Caccamo, Salvatore Oddo, Frank M Laferla, Ian Parker. J Neurosci 2006
Grace E Stutzmann, Ian Smith, Antonella Caccamo, Salvatore Oddo, Frank M Laferla, Ian Parker. J Neurosci 2006
8
8
Familial Alzheimer disease-linked mutations specifically disrupt Ca2+ leak function of presenilin 1.
Omar Nelson, Huiping Tu, Tianhua Lei, Mostafa Bentahir, Bart de Strooper, Ilya Bezprozvanny. J Clin Invest 2007
Omar Nelson, Huiping Tu, Tianhua Lei, Mostafa Bentahir, Bart de Strooper, Ilya Bezprozvanny. J Clin Invest 2007
8
Abeta plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks.
Kishore V Kuchibhotla, Samuel T Goldman, Carli R Lattarulo, Hai-Yan Wu, Bradley T Hyman, Brian J Bacskai. Neuron 2008
Kishore V Kuchibhotla, Samuel T Goldman, Carli R Lattarulo, Hai-Yan Wu, Bradley T Hyman, Brian J Bacskai. Neuron 2008
8
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics.
John Hardy, Dennis J Selkoe. Science 2002
John Hardy, Dennis J Selkoe. Science 2002
8
Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease.
Frank M LaFerla. Nat Rev Neurosci 2002
Frank M LaFerla. Nat Rev Neurosci 2002
8
Involvement of endoplasmic reticulum Ca2+ release through ryanodine and inositol 1,4,5-triphosphate receptors in the neurotoxic effects induced by the amyloid-beta peptide.
Elisabete Ferreiro, Catarina R Oliveira, Cláudia Pereira. J Neurosci Res 2004
Elisabete Ferreiro, Catarina R Oliveira, Cláudia Pereira. J Neurosci Res 2004
8
Deviant ryanodine receptor-mediated calcium release resets synaptic homeostasis in presymptomatic 3xTg-AD mice.
Shreaya Chakroborty, Ivan Goussakov, Megan B Miller, Grace E Stutzmann. J Neurosci 2009
Shreaya Chakroborty, Ivan Goussakov, Megan B Miller, Grace E Stutzmann. J Neurosci 2009
8
Mitochondria as sensors and regulators of calcium signalling.
Rosario Rizzuto, Diego De Stefani, Anna Raffaello, Cristina Mammucari. Nat Rev Mol Cell Biol 2012
Rosario Rizzuto, Diego De Stefani, Anna Raffaello, Cristina Mammucari. Nat Rev Mol Cell Biol 2012
8
Calcium signalling: dynamics, homeostasis and remodelling.
Michael J Berridge, Martin D Bootman, H Llewelyn Roderick. Nat Rev Mol Cell Biol 2003
Michael J Berridge, Martin D Bootman, H Llewelyn Roderick. Nat Rev Mol Cell Biol 2003
8
A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter.
Diego De Stefani, Anna Raffaello, Enrico Teardo, Ildikò Szabò, Rosario Rizzuto. Nature 2011
Diego De Stefani, Anna Raffaello, Enrico Teardo, Ildikò Szabò, Rosario Rizzuto. Nature 2011
8
Calcium and ROS: A mutual interplay.
Agnes Görlach, Katharina Bertram, Sona Hudecova, Olga Krizanova. Redox Biol 2015
Agnes Görlach, Katharina Bertram, Sona Hudecova, Olga Krizanova. Redox Biol 2015
8
Susceptibility to Calcium Dysregulation during Brain Aging.
Ashok Kumar, Karthik Bodhinathan, Thomas C Foster. Front Aging Neurosci 2009
Ashok Kumar, Karthik Bodhinathan, Thomas C Foster. Front Aging Neurosci 2009
9
Neuronal calcium signaling: function and dysfunction.
Marisa Brini, Tito Calì, Denis Ottolini, Ernesto Carafoli. Cell Mol Life Sci 2014
Marisa Brini, Tito Calì, Denis Ottolini, Ernesto Carafoli. Cell Mol Life Sci 2014
7
Amyloid beta oligomers (A beta(1-42) globulomer) suppress spontaneous synaptic activity by inhibition of P/Q-type calcium currents.
Volker Nimmrich, Christiane Grimm, Andreas Draguhn, Stefan Barghorn, Alexander Lehmann, Hans Schoemaker, Heinz Hillen, Gerhard Gross, Ulrich Ebert, Claus Bruehl. J Neurosci 2008
Volker Nimmrich, Christiane Grimm, Andreas Draguhn, Stefan Barghorn, Alexander Lehmann, Hans Schoemaker, Heinz Hillen, Gerhard Gross, Ulrich Ebert, Claus Bruehl. J Neurosci 2008
7
Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.
Angela M Bruno, Jeff Y Huang, David A Bennett, Robert A Marr, Michelle L Hastings, Grace E Stutzmann. Neurobiol Aging 2012
Angela M Bruno, Jeff Y Huang, David A Bennett, Robert A Marr, Michelle L Hastings, Grace E Stutzmann. Neurobiol Aging 2012
8
Gain-of-function enhancement of IP3 receptor modal gating by familial Alzheimer's disease-linked presenilin mutants in human cells and mouse neurons.
King-Ho Cheung, Lijuan Mei, Don-On Daniel Mak, Ikuo Hayashi, Takeshi Iwatsubo, David E Kang, J Kevin Foskett. Sci Signal 2010
King-Ho Cheung, Lijuan Mei, Don-On Daniel Mak, Ikuo Hayashi, Takeshi Iwatsubo, David E Kang, J Kevin Foskett. Sci Signal 2010
7
Neuronal store-operated calcium entry pathway as a novel therapeutic target for Huntington's disease treatment.
Jun Wu, Hsin-Pei Shih, Vladimir Vigont, Lori Hrdlicka, Len Diggins, Carol Singh, Matt Mahoney, Richard Chesworth, Gideon Shapiro, Olga Zimina,[...]. Chem Biol 2011
Jun Wu, Hsin-Pei Shih, Vladimir Vigont, Lori Hrdlicka, Len Diggins, Carol Singh, Matt Mahoney, Richard Chesworth, Gideon Shapiro, Olga Zimina,[...]. Chem Biol 2011
7
Familial Alzheimer's disease-associated presenilin 1 mutants promote γ-secretase cleavage of STIM1 to impair store-operated Ca2+ entry.
Benjamin Chun-Kit Tong, Claire Shuk-Kwan Lee, Wing-Hei Cheng, Kwok-On Lai, J Kevin Foskett, King-Ho Cheung. Sci Signal 2016
Benjamin Chun-Kit Tong, Claire Shuk-Kwan Lee, Wing-Hei Cheng, Kwok-On Lai, J Kevin Foskett, King-Ho Cheung. Sci Signal 2016
12
Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability.
Grace E Stutzmann, Antonella Caccamo, Frank M LaFerla, Ian Parker. J Neurosci 2004
Grace E Stutzmann, Antonella Caccamo, Frank M LaFerla, Ian Parker. J Neurosci 2004
7
Dantrolene is neuroprotective in Huntington's disease transgenic mouse model.
Xi Chen, Jun Wu, Svetlana Lvovskaya, Emily Herndon, Charlene Supnet, Ilya Bezprozvanny. Mol Neurodegener 2011
Xi Chen, Jun Wu, Svetlana Lvovskaya, Emily Herndon, Charlene Supnet, Ilya Bezprozvanny. Mol Neurodegener 2011
10
Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum.
N Arispe, E Rojas, H B Pollard. Proc Natl Acad Sci U S A 1993
N Arispe, E Rojas, H B Pollard. Proc Natl Acad Sci U S A 1993
7
Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway.
Ganesh M Shankar, Brenda L Bloodgood, Matthew Townsend, Dominic M Walsh, Dennis J Selkoe, Bernardo L Sabatini. J Neurosci 2007
Ganesh M Shankar, Brenda L Bloodgood, Matthew Townsend, Dominic M Walsh, Dennis J Selkoe, Bernardo L Sabatini. J Neurosci 2007
7
Calcium signaling in neurodegeneration.
Philippe Marambaud, Ute Dreses-Werringloer, Valérie Vingtdeux. Mol Neurodegener 2009
Philippe Marambaud, Ute Dreses-Werringloer, Valérie Vingtdeux. Mol Neurodegener 2009
7
Calcium signaling and amyloid toxicity in Alzheimer disease.
Angelo Demuro, Ian Parker, Grace E Stutzmann. J Biol Chem 2010
Angelo Demuro, Ian Parker, Grace E Stutzmann. J Biol Chem 2010
7
Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine.
Fernanda G De Felice, Pauline T Velasco, Mary P Lambert, Kirsten Viola, Sara J Fernandez, Sergio T Ferreira, William L Klein. J Biol Chem 2007
Fernanda G De Felice, Pauline T Velasco, Mary P Lambert, Kirsten Viola, Sara J Fernandez, Sergio T Ferreira, William L Klein. J Biol Chem 2007
6
SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production.
Kim N Green, Angelo Demuro, Yama Akbari, Brian D Hitt, Ian F Smith, Ian Parker, Frank M LaFerla. J Cell Biol 2008
Kim N Green, Angelo Demuro, Yama Akbari, Brian D Hitt, Ian F Smith, Ian Parker, Frank M LaFerla. J Cell Biol 2008
6
Store-Operated Calcium Channel Complex in Postsynaptic Spines: A New Therapeutic Target for Alzheimer's Disease Treatment.
Hua Zhang, Suya Sun, Lili Wu, Ekaterina Pchitskaya, Olga Zakharova, Klementina Fon Tacer, Ilya Bezprozvanny. J Neurosci 2016
Hua Zhang, Suya Sun, Lili Wu, Ekaterina Pchitskaya, Olga Zakharova, Klementina Fon Tacer, Ilya Bezprozvanny. J Neurosci 2016
8
Regulation of NMDA receptor trafficking by amyloid-beta.
Eric M Snyder, Yi Nong, Claudia G Almeida, Surojit Paul, Timothy Moran, Eun Young Choi, Angus C Nairn, Michael W Salter, Paul J Lombroso, Gunnar K Gouras,[...]. Nat Neurosci 2005
Eric M Snyder, Yi Nong, Claudia G Almeida, Surojit Paul, Timothy Moran, Eun Young Choi, Angus C Nairn, Michael W Salter, Paul J Lombroso, Gunnar K Gouras,[...]. Nat Neurosci 2005
6
The cytosolic N-terminus of presenilin-1 potentiates mouse ryanodine receptor single channel activity.
Volodymyr Rybalchenko, Sung-Yong Hwang, Nataliya Rybalchenko, Peter Koulen. Int J Biochem Cell Biol 2008
Volodymyr Rybalchenko, Sung-Yong Hwang, Nataliya Rybalchenko, Peter Koulen. Int J Biochem Cell Biol 2008
8
Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice.
M A Leissring, Y Akbari, C M Fanger, M D Cahalan, M P Mattson, F M LaFerla. J Cell Biol 2000
M A Leissring, Y Akbari, C M Fanger, M D Cahalan, M P Mattson, F M LaFerla. J Cell Biol 2000
6
Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease.
Melinda M Zeron, Oskar Hansson, Nansheng Chen, Cheryl L Wellington, Blair R Leavitt, Patrik Brundin, Michael R Hayden, Lynn A Raymond. Neuron 2002
Melinda M Zeron, Oskar Hansson, Nansheng Chen, Cheryl L Wellington, Blair R Leavitt, Patrik Brundin, Michael R Hayden, Lynn A Raymond. Neuron 2002
6
The synaptic maintenance problem: membrane recycling, Ca2+ homeostasis and late onset degeneration.
Ilya Bezprozvanny, Peter Robin Hiesinger. Mol Neurodegener 2013
Ilya Bezprozvanny, Peter Robin Hiesinger. Mol Neurodegener 2013
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.