A citation-based method for searching scientific literature


List of co-cited articles
730 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


AMPK phosphorylation of raptor mediates a metabolic checkpoint.
Dana M Gwinn, David B Shackelford, Daniel F Egan, Maria M Mihaylova, Annabelle Mery, Debbie S Vasquez, Benjamin E Turk, Reuben J Shaw. Mol Cell 2008
19

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.
Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan. Nat Cell Biol 2011
17


The LKB1-AMPK pathway: metabolism and growth control in tumour suppression.
David B Shackelford, Reuben J Shaw. Nat Rev Cancer 2009
11

AMPK: guardian of metabolism and mitochondrial homeostasis.
Sébastien Herzig, Reuben J Shaw. Nat Rev Mol Cell Biol 2018
916
10

mTOR signaling in growth control and disease.
Mathieu Laplante, David M Sabatini. Cell 2012
8

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress.
Reuben J Shaw, Monica Kosmatka, Nabeel Bardeesy, Rebecca L Hurley, Lee A Witters, Ronald A DePinho, Lewis C Cantley. Proc Natl Acad Sci U S A 2004
8

AMPK: a nutrient and energy sensor that maintains energy homeostasis.
D Grahame Hardie, Fiona A Ross, Simon A Hawley. Nat Rev Mol Cell Biol 2012
8

Role of AMP-activated protein kinase in mechanism of metformin action.
G Zhou, R Myers, Y Li, Y Chen, X Shen, J Fenyk-Melody, M Wu, J Ventre, T Doebber, N Fujii,[...]. J Clin Invest 2001
8

mTOR Signaling in Growth, Metabolism, and Disease.
Robert A Saxton, David M Sabatini. Cell 2017
886
7

mTOR Signaling in Growth, Metabolism, and Disease.
Robert A Saxton, David M Sabatini. Cell 2017
7

Upstream and downstream of mTOR.
Nissim Hay, Nahum Sonenberg. Genes Dev 2004
6

TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth.
Ken Inoki, Hongjiao Ouyang, Tianqing Zhu, Charlotta Lindvall, Yian Wang, Xiaojie Zhang, Qian Yang, Christina Bennett, Yuko Harada, Kryn Stankunas,[...]. Cell 2006
933
6


Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase.
Anila K Madiraju, Derek M Erion, Yasmeen Rahimi, Xian-Man Zhang, Demetrios T Braddock, Ronald A Albright, Brett J Prigaro, John L Wood, Sanjay Bhanot, Michael J MacDonald,[...]. Nature 2014
672
6

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB.
Dos D Sarbassov, Siraj M Ali, Shomit Sengupta, Joon-Ho Sheen, Peggy P Hsu, Alex F Bagley, Andrew L Markhard, David M Sabatini. Mol Cell 2006
5

Activation of a metabolic gene regulatory network downstream of mTOR complex 1.
Katrin Düvel, Jessica L Yecies, Suchithra Menon, Pichai Raman, Alex I Lipovsky, Amanda L Souza, Ellen Triantafellow, Qicheng Ma, Regina Gorski, Stephen Cleaver,[...]. Mol Cell 2010
5


mTOR signaling at a glance.
Mathieu Laplante, David M Sabatini. J Cell Sci 2009
5

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
5

mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex.
John T Cunningham, Joseph T Rodgers, Daniel H Arlow, Francisca Vazquez, Vamsi K Mootha, Pere Puigserver. Nature 2007
942
5

LKB1 modulates lung cancer differentiation and metastasis.
Hongbin Ji, Matthew R Ramsey, D Neil Hayes, Cheng Fan, Kate McNamara, Piotr Kozlowski, Chad Torrice, Michael C Wu, Takeshi Shimamura, Samanthi A Perera,[...]. Nature 2007
701
5

Metformin improves healthspan and lifespan in mice.
Alejandro Martin-Montalvo, Evi M Mercken, Sarah J Mitchell, Hector H Palacios, Patricia L Mote, Morten Scheibye-Knudsen, Ana P Gomes, Theresa M Ward, Robin K Minor, Marie-José Blouin,[...]. Nat Commun 2013
690
5

Metformin: from mechanisms of action to therapies.
Marc Foretz, Bruno Guigas, Luc Bertrand, Michael Pollak, Benoit Viollet. Cell Metab 2014
611
5

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity.
Carles Cantó, Zachary Gerhart-Hines, Jerome N Feige, Marie Lagouge, Lilia Noriega, Jill C Milne, Peter J Elliott, Pere Puigserver, Johan Auwerx. Nature 2009
5

Metformin Inhibits Hepatic mTORC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex.
Jessica J Howell, Kristina Hellberg, Marc Turner, George Talbott, Matthew J Kolar, Debbie S Ross, Gerta Hoxhaj, Alan Saghatelian, Reuben J Shaw, Brendan D Manning. Cell Metab 2017
168
5


The TSC1-TSC2 complex: a molecular switchboard controlling cell growth.
Jingxiang Huang, Brendan D Manning. Biochem J 2008
785
5

Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria.
Hannah R Bridges, Andrew J Y Jones, Michael N Pollak, Judy Hirst. Biochem J 2014
364
4

SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth.
Thomas Porstmann, Claudio R Santos, Beatrice Griffiths, Megan Cully, Mary Wu, Sally Leevers, John R Griffiths, Yuen-Li Chung, Almut Schulze. Cell Metab 2008
785
4

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.
Yasemin Sancak, Timothy R Peterson, Yoav D Shaul, Robert A Lindquist, Carson C Thoreen, Liron Bar-Peled, David M Sabatini. Science 2008
4

Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
4

On the origin of cancer cells.
O WARBURG. Science 1956
4

Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK.
Chen-Song Zhang, Simon A Hawley, Yue Zong, Mengqi Li, Zhichao Wang, Alexander Gray, Teng Ma, Jiwen Cui, Jin-Wei Feng, Mingjiang Zhu,[...]. Nature 2017
249
4

The Dawn of the Age of Amino Acid Sensors for the mTORC1 Pathway.
Rachel L Wolfson, David M Sabatini. Cell Metab 2017
255
4

Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks.
Sebastian Alers, Antje S Löffler, Sebastian Wesselborg, Björn Stork. Mol Cell Biol 2012
765
4

Regulation of mTORC1 by amino acids.
Liron Bar-Peled, David M Sabatini. Trends Cell Biol 2014
498
4

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling.
Ken Inoki, Yong Li, Tian Xu, Kun-Liang Guan. Genes Dev 2003
4

Metformin and reduced risk of cancer in diabetic patients.
Josie M M Evans, Louise A Donnelly, Alistair M Emslie-Smith, Dario R Alessi, Andrew D Morris. BMJ 2005
4

Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1.
Isaam Ben Sahra, Claire Regazzetti, Guillaume Robert, Kathiane Laurent, Yannick Le Marchand-Brustel, Patrick Auberger, Jean-François Tanti, Sophie Giorgetti-Peraldi, Frédéric Bost. Cancer Res 2011
428
4


LKB1 is the upstream kinase in the AMP-activated protein kinase cascade.
Angela Woods, Stephen R Johnstone, Kristina Dickerson, Fiona C Leiper, Lee G D Fryer, Dietbert Neumann, Uwe Schlattner, Theo Wallimann, Marian Carlson, David Carling. Curr Biol 2003
4

Aging-associated reductions in AMP-activated protein kinase activity and mitochondrial biogenesis.
Richard M Reznick, Haihong Zong, Ji Li, Katsutaro Morino, Irene K Moore, Hannah J Yu, Zhen-Xiang Liu, Jianying Dong, Kirsty J Mustard, Simon A Hawley,[...]. Cell Metab 2007
348
4

A serine/threonine kinase gene defective in Peutz-Jeghers syndrome.
A Hemminki, D Markie, I Tomlinson, E Avizienyte, S Roth, A Loukola, G Bignell, W Warren, M Aminoff, P Höglund,[...]. Nature 1998
4

Cellular and molecular mechanisms of metformin: an overview.
Benoit Viollet, Bruno Guigas, Nieves Sanz Garcia, Jocelyne Leclerc, Marc Foretz, Fabrizio Andreelli. Clin Sci (Lond) 2012
964
4

Wnt/beta-catenin signaling: components, mechanisms, and diseases.
Bryan T MacDonald, Keiko Tamai, Xi He. Dev Cell 2009
4

Autophagy in the pathogenesis of disease.
Beth Levine, Guido Kroemer. Cell 2008
4

Autophagy: cellular and molecular mechanisms.
Danielle Glick, Sandra Barth, Kay F Macleod. J Pathol 2010
4

Autophagy: process and function.
Noboru Mizushima. Genes Dev 2007
4

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice.
Masaaki Komatsu, Satoshi Waguri, Takashi Ueno, Junichi Iwata, Shigeo Murata, Isei Tanida, Junji Ezaki, Noboru Mizushima, Yoshinori Ohsumi, Yasuo Uchiyama,[...]. J Cell Biol 2005
4


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.