A citation-based method for searching scientific literature

Kathleen Cullion, Kyle M Draheim, Nicole Hermance, Jennifer Tammam, Vishva M Sharma, Christopher Ware, George Nikov, Veena Krishnamoorthy, Pradip K Majumder, Michelle A Kelliher. Blood 2009
Times Cited: 106







List of co-cited articles
1124 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Andrew P Weng, Adolfo A Ferrando, Woojoong Lee, John P Morris, Lewis B Silverman, Cheryll Sanchez-Irizarry, Stephen C Blacklow, A Thomas Look, Jon C Aster. Science 2004
65

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia.
Teresa Palomero, Maria Luisa Sulis, Maria Cortina, Pedro J Real, Kelly Barnes, Maria Ciofani, Esther Caparros, Jean Buteau, Kristy Brown, Sherrie L Perkins,[...]. Nat Med 2007
660
50

Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia.
Pedro J Real, Valeria Tosello, Teresa Palomero, Mireia Castillo, Eva Hernando, Elisa de Stanchina, Maria Luisa Sulis, Kelly Barnes, Catherine Sawai, Irene Homminga,[...]. Nat Med 2009
323
50

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
Jennifer O'Neil, Jonathan Grim, Peter Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James Hardwick, Markus Welcker, Jules P Meijerink, Rob Pieters,[...]. J Exp Med 2007
494
37

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth.
Teresa Palomero, Wei Keat Lim, Duncan T Odom, Maria Luisa Sulis, Pedro J Real, Adam Margolin, Kelly C Barnes, Jennifer O'Neil, Donna Neuberg, Andrew P Weng,[...]. Proc Natl Acad Sci U S A 2006
592
36

c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma.
Andrew P Weng, John M Millholland, Yumi Yashiro-Ohtani, Marie Laure Arcangeli, Arthur Lau, Carol Wai, Cristina Del Bianco, Carlos G Rodriguez, Hong Sai, John Tobias,[...]. Genes Dev 2006
627
35

Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemia.
Steven M Chan, Andrew P Weng, Robert Tibshirani, Jon C Aster, Paul J Utz. Blood 2007
201
32

TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms.
L W Ellisen, J Bird, D C West, A L Soreng, T C Reynolds, S D Smith, J Sklar. Cell 1991
29

Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc.
Vishva Mitra Sharma, Jennifer A Calvo, Kyle M Draheim, Leslie A Cunningham, Nicole Hermance, Levi Beverly, Veena Krishnamoorthy, Manoj Bhasin, Anthony J Capobianco, Michelle A Kelliher. Mol Cell Biol 2006
207
28

The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia.
Benjamin J Thompson, Silvia Buonamici, Maria Luisa Sulis, Teresa Palomero, Tomas Vilimas, Giuseppe Basso, Adolfo Ferrando, Iannis Aifantis. J Exp Med 2007
348
27

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells.
Johan H van Es, Marielle E van Gijn, Orbicia Riccio, Maaike van den Born, Marc Vooijs, Harry Begthel, Miranda Cozijnsen, Sylvie Robine, Doug J Winton, Freddy Radtke,[...]. Nature 2005
27


Direct inhibition of the NOTCH transcription factor complex.
Raymond E Moellering, Melanie Cornejo, Tina N Davis, Cristina Del Bianco, Jon C Aster, Stephen C Blacklow, Andrew L Kung, D Gary Gilliland, Gregory L Verdine, James E Bradner. Nature 2009
559
25

Therapeutic antibody targeting of individual Notch receptors.
Yan Wu, Carol Cain-Hom, Lisa Choy, Thijs J Hagenbeek, Gladys P de Leon, Yongmei Chen, David Finkle, Rayna Venook, Xiumin Wu, John Ridgway,[...]. Nature 2010
516
24

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles.
W S Pear, J C Aster, M L Scott, R P Hasserjian, B Soffer, J Sklar, D Baltimore. J Exp Med 1996
563
23

Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemia.
Mark Y Chiang, Lanwei Xu, Olga Shestova, Gavin Histen, Sarah L'heureux, Candice Romany, M Eden Childs, Phyllis A Gimotty, Jon C Aster, Warren S Pear. J Clin Invest 2008
164
23

CSL-MAML-dependent Notch1 signaling controls T lineage-specific IL-7R{alpha} gene expression in early human thymopoiesis and leukemia.
Sara González-García, Marina García-Peydró, Enrique Martín-Gayo, Esteban Ballestar, Manel Esteller, Rafael Bornstein, José Luis de la Pompa, Adolfo A Ferrando, María L Toribio. J Exp Med 2009
106
19

NOTCH is a key regulator of human T-cell acute leukemia initiating cell activity.
Florence Armstrong, Philippe Brunet de la Grange, Bastien Gerby, Marie-Christine Rouyez, Julien Calvo, Michaéla Fontenay, Nicolas Boissel, Hervé Dombret, André Baruchel, Judith Landman-Parker,[...]. Blood 2009
114
19

Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes.
Michael J Malecki, Cheryll Sanchez-Irizarry, Jennifer L Mitchell, Gavin Histen, Mina L Xu, Jon C Aster, Stephen C Blacklow. Mol Cell Biol 2006
186
19


Inhibition of NOTCH signaling by gamma secretase inhibitor engages the RB pathway and elicits cell cycle exit in T-cell acute lymphoblastic leukemia cells.
Sudhir S Rao, Jennifer O'Neil, Cole D Liberator, James S Hardwick, Xudong Dai, Theresa Zhang, Edyta Tyminski, Jing Yuan, Nancy E Kohl, Victoria M Richon,[...]. Cancer Res 2009
107
19

Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors.
Miguel Aste-Amézaga, Ningyan Zhang, Janet E Lineberger, Beth A Arnold, Timothy J Toner, Mingcheng Gu, Lingyi Huang, Salvatore Vitelli, Kim T Vo, Peter Haytko,[...]. PLoS One 2010
130
19

Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss.
Hind Medyouf, Xiuhua Gao, Florence Armstrong, Samuel Gusscott, Qing Liu, Amanda Larson Gedman, Larry H Matherly, Kirk R Schultz, Francoise Pflumio, Mingjian James You,[...]. Blood 2010
65
27

Notch signaling in leukemia.
Jon C Aster, Warren S Pear, Stephen C Blacklow. Annu Rev Pathol 2008
197
17

Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling.
Andrew P Weng, Yunsun Nam, Michael S Wolfe, Warren S Pear, James D Griffin, Stephen C Blacklow, Jon C Aster. Mol Cell Biol 2003
303
17

High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia.
Alejandro Gutierrez, Takaomi Sanda, Ruta Grebliunaite, Arkaitz Carracedo, Leonardo Salmena, Yebin Ahn, Suzanne Dahlberg, Donna Neuberg, Lisa A Moreau, Stuart S Winter,[...]. Blood 2009
318
17

PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability.
Ana Silva, J Andrés Yunes, Bruno A Cardoso, Leila R Martins, Patrícia Y Jotta, Miguel Abecasis, Alexandre E Nowill, Nick R Leslie, Angelo A Cardoso, Joao T Barata. J Clin Invest 2008
324
16

Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia.
Tomas Vilimas, Joaquina Mascarenhas, Teresa Palomero, Malay Mandal, Silvia Buonamici, Fanyong Meng, Benjamín Thompson, Christina Spaulding, Sami Macaroun, Maria-Luisa Alegre,[...]. Nat Med 2007
249
16

Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases.
Ila Joshi, Lisa M Minter, Janice Telfer, Renée M Demarest, Anthony J Capobianco, Jon C Aster, Piotr Sicinski, Abdul Fauq, Todd E Golde, Barbara A Osborne. Blood 2009
131
16

CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement, aberrant NOTCH1 activation and high sensitivity to gamma-secretase inhibitors.
T Palomero, K C Barnes, P J Real, J L Glade Bender, M L Sulis, V V Murty, A I Colovai, M Balbin, A A Ferrando. Leukemia 2006
111
16

Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2.
Orbicia Riccio, Marielle E van Gijn, April C Bezdek, Luca Pellegrinet, Johan H van Es, Ursula Zimber-Strobl, Lothar J Strobl, Tasuku Honjo, Hans Clevers, Freddy Radtke. EMBO Rep 2008
289
16

A Phase 1 study of the novel gamma-secretase inhibitor PF-03084014 in patients with T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma.
C Papayannidis, D J DeAngelo, W Stock, B Huang, M N Shaik, R Cesari, X Zheng, J M Reynolds, P A English, M Ozeck,[...]. Blood Cancer J 2015
71
22

Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation.
Joseph Milano, Jenny McKay, Claude Dagenais, Linda Foster-Brown, Francois Pognan, Reto Gadient, Robert T Jacobs, Anna Zacco, Barry Greenberg, Paul J Ciaccio. Toxicol Sci 2004
412
15


Deficient T cell fate specification in mice with an induced inactivation of Notch1.
F Radtke, A Wilson, G Stark, M Bauer, J van Meerwijk, H R MacDonald, M Aguet. Immunity 1999
15

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia.
Xose S Puente, Magda Pinyol, Víctor Quesada, Laura Conde, Gonzalo R Ordóñez, Neus Villamor, Georgia Escaramis, Pedro Jares, Sílvia Beà, Marcos González-Díaz,[...]. Nature 2011
15

The role of the PTEN/AKT Pathway in NOTCH1-induced leukemia.
Teresa Palomero, Maria Dominguez, Adolfo A Ferrando. Cell Cycle 2008
178
14

Activating Notch1 mutations in mouse models of T-ALL.
Jennifer O'Neil, Jennifer Calvo, Keith McKenna, Veena Krishnamoorthy, Jon C Aster, Craig H Bassing, Frederick W Alt, Michelle Kelliher, A Thomas Look. Blood 2006
184
14

Structural basis for autoinhibition of Notch.
Wendy R Gordon, Didem Vardar-Ulu, Gavin Histen, Cheryll Sanchez-Irizarry, Jon C Aster, Stephen C Blacklow. Nat Struct Mol Biol 2007
236
14

Evaluation of selective gamma-secretase inhibitor PF-03084014 for its antitumor efficacy and gastrointestinal safety to guide optimal clinical trial design.
Ping Wei, Marlena Walls, Ming Qiu, Richard Ding, Robert H Denlinger, Anthony Wong, Kosta Tsaparikos, Jitesh P Jani, Natilie Hosea, Michelle Sands,[...]. Mol Cancer Ther 2010
143
14

Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia.
Adolfo A Ferrando, Donna S Neuberg, Jane Staunton, Mignon L Loh, Christine Huard, Susana C Raimondi, Fred G Behm, Ching Hon Pui, James R Downing, D Gary Gilliland,[...]. Cancer Cell 2002
782
14

NOTCH1/FBXW7 mutation identifies a large subgroup with favorable outcome in adult T-cell acute lymphoblastic leukemia (T-ALL): a Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL) study.
Vahid Asnafi, Agnès Buzyn, Sandrine Le Noir, Frédéric Baleydier, Arnauld Simon, Kheira Beldjord, Oumedaly Reman, Francis Witz, Thierry Fagot, Emmanuelle Tavernier,[...]. Blood 2009
149
14

NOTCH1 extracellular juxtamembrane expansion mutations in T-ALL.
Maria Luisa Sulis, Odette Williams, Teresa Palomero, Valeria Tosello, Sasikala Pallikuppam, Pedro J Real, Kelly Barnes, Linda Zuurbier, Jules P Meijerink, Adolfo A Ferrando. Blood 2008
91
15

High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling.
Hind Medyouf, Samuel Gusscott, Hongfang Wang, Jen-Chieh Tseng, Carol Wai, Oksana Nemirovsky, Andreas Trumpp, Francoise Pflumio, Joan Carboni, Marco Gottardis,[...]. J Exp Med 2011
121
14

Notch1 inhibition targets the leukemia-initiating cells in a Tal1/Lmo2 mouse model of T-ALL.
Jessica Tatarek, Kathleen Cullion, Todd Ashworth, Rachel Gerstein, Jon C Aster, Michelle A Kelliher. Blood 2011
70
20

Preclinical analysis of the γ-secretase inhibitor PF-03084014 in combination with glucocorticoids in T-cell acute lymphoblastic leukemia.
Jeremy B Samon, Mireia Castillo-Martin, Michael Hadler, Alberto Ambesi-Impiobato, Elisabeth Paietta, Janis Racevskis, Peter H Wiernik, Jacob M Rowe, John Jakubczak, Sophia Randolph,[...]. Mol Cancer Ther 2012
83
16

An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.
Birgit Knoechel, Justine E Roderick, Kaylyn E Williamson, Jiang Zhu, Jens G Lohr, Matthew J Cotton, Shawn M Gillespie, Daniel Fernandez, Manching Ku, Hongfang Wang,[...]. Nat Genet 2014
236
14

Notch signalling: a simple pathway becomes complex.
Sarah J Bray. Nat Rev Mol Cell Biol 2006
13

Oncogenesis of T-ALL and nonmalignant consequences of overexpressing intracellular NOTCH1.
Xiaoyu Li, Fotini Gounari, Alexei Protopopov, Khashayarsha Khazaie, Harald von Boehmer. J Exp Med 2008
70
18

Structure of the Notch1-negative regulatory region: implications for normal activation and pathogenic signaling in T-ALL.
Wendy R Gordon, Monideepa Roy, Didem Vardar-Ulu, Megan Garfinkel, Marc R Mansour, Jon C Aster, Stephen C Blacklow. Blood 2009
117
13


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.