David A Brown, Gayle M Passmore. Br J Pharmacol 2009
Times Cited: 444
Times Cited: 444
Times Cited
Times Co-cited
Similarity
KCNQ2 and KCNQ3 potassium channel subunits: molecular correlates of the M-channel.
H S Wang, Z Pan, W Shi, B S Brown, R S Wymore, I S Cohen, J E Dixon, D McKinnon. Science 1998
H S Wang, Z Pan, W Shi, B S Brown, R S Wymore, I S Cohen, J E Dixon, D McKinnon. Science 1998
35
Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neurone.
D A Brown, P R Adams. Nature 1980
D A Brown, P R Adams. Nature 1980
28
Neuronal KCNQ potassium channels: physiology and role in disease.
T J Jentsch. Nat Rev Neurosci 2000
T J Jentsch. Nat Rev Neurosci 2000
27
Pathways modulating neural KCNQ/M (Kv7) potassium channels.
Patrick Delmas, David A Brown. Nat Rev Neurosci 2005
Patrick Delmas, David A Brown. Nat Rev Neurosci 2005
26
KCNQ potassium channels: physiology, pathophysiology, and pharmacology.
J Robbins. Pharmacol Ther 2001
J Robbins. Pharmacol Ther 2001
18
PIP(2) activates KCNQ channels, and its hydrolysis underlies receptor-mediated inhibition of M currents.
Hailin Zhang, Liviu C Craciun, Tooraj Mirshahi, Tibor Rohács, Coeli M B Lopes, Taihao Jin, Diomedes E Logothetis. Neuron 2003
Hailin Zhang, Liviu C Craciun, Tooraj Mirshahi, Tibor Rohács, Coeli M B Lopes, Taihao Jin, Diomedes E Logothetis. Neuron 2003
18
The mechanism of action of retigabine (ezogabine), a first-in-class K+ channel opener for the treatment of epilepsy.
Martin J Gunthorpe, Charles H Large, Raman Sankar. Epilepsia 2012
Martin J Gunthorpe, Charles H Large, Raman Sankar. Epilepsia 2012
18
A potassium channel mutation in neonatal human epilepsy.
C Biervert, B C Schroeder, C Kubisch, S F Berkovic, P Propping, T J Jentsch, O K Steinlein. Science 1998
C Biervert, B C Schroeder, C Kubisch, S F Berkovic, P Propping, T J Jentsch, O K Steinlein. Science 1998
17
Conditional transgenic suppression of M channels in mouse brain reveals functions in neuronal excitability, resonance and behavior.
H Christian Peters, Hua Hu, Olaf Pongs, Johan F Storm, Dirk Isbrandt. Nat Neurosci 2005
H Christian Peters, Hua Hu, Olaf Pongs, Johan F Storm, Dirk Isbrandt. Nat Neurosci 2005
17
Modulation of Kv7 channels and excitability in the brain.
Derek L Greene, Naoto Hoshi. Cell Mol Life Sci 2017
Derek L Greene, Naoto Hoshi. Cell Mol Life Sci 2017
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Functional significance of axonal Kv7 channels in hippocampal pyramidal neurons.
Mala M Shah, Michele Migliore, Ignacio Valencia, Edward C Cooper, David A Brown. Proc Natl Acad Sci U S A 2008
Mala M Shah, Michele Migliore, Ignacio Valencia, Edward C Cooper, David A Brown. Proc Natl Acad Sci U S A 2008
16
A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns.
N A Singh, C Charlier, D Stauffer, B R DuPont, R J Leach, R Melis, G M Ronen, I Bjerre, T Quattlebaum, J V Murphy,[...]. Nat Genet 1998
N A Singh, C Charlier, D Stauffer, B R DuPont, R J Leach, R Melis, G M Ronen, I Bjerre, T Quattlebaum, J V Murphy,[...]. Nat Genet 1998
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Conditional deletions of epilepsy-associated KCNQ2 and KCNQ3 channels from cerebral cortex cause differential effects on neuronal excitability.
Heun Soh, Rima Pant, Joseph J LoTurco, Anastasios V Tzingounis. J Neurosci 2014
Heun Soh, Rima Pant, Joseph J LoTurco, Anastasios V Tzingounis. J Neurosci 2014
22
KCNQ2 is a nodal K+ channel.
Jérôme J Devaux, Kleopas A Kleopa, Edward C Cooper, Steven S Scherer. J Neurosci 2004
Jérôme J Devaux, Kleopas A Kleopa, Edward C Cooper, Steven S Scherer. J Neurosci 2004
15
KCNQ2 encephalopathy: emerging phenotype of a neonatal epileptic encephalopathy.
Sarah Weckhuysen, Simone Mandelstam, Arvid Suls, Dominique Audenaert, Tine Deconinck, Lieve R F Claes, Liesbet Deprez, Katrien Smets, Dimitrina Hristova, Iglika Yordanova,[...]. Ann Neurol 2012
Sarah Weckhuysen, Simone Mandelstam, Arvid Suls, Dominique Audenaert, Tine Deconinck, Lieve R F Claes, Liesbet Deprez, Katrien Smets, Dimitrina Hristova, Iglika Yordanova,[...]. Ann Neurol 2012
15
A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon.
Zongming Pan, Tingching Kao, Zsolt Horvath, Julia Lemos, Jai-Yoon Sul, Stephen D Cranstoun, Vann Bennett, Steven S Scherer, Edward C Cooper. J Neurosci 2006
Zongming Pan, Tingching Kao, Zsolt Horvath, Julia Lemos, Jai-Yoon Sul, Stephen D Cranstoun, Vann Bennett, Steven S Scherer, Edward C Cooper. J Neurosci 2006
14
Recovery from muscarinic modulation of M current channels requires phosphatidylinositol 4,5-bisphosphate synthesis.
Byung-Chang Suh, Bertil Hille. Neuron 2002
Byung-Chang Suh, Bertil Hille. Neuron 2002
13
Cryo-EM Structure of a KCNQ1/CaM Complex Reveals Insights into Congenital Long QT Syndrome.
Ji Sun, Roderick MacKinnon. Cell 2017
Ji Sun, Roderick MacKinnon. Cell 2017
13
KCNQ5, a novel potassium channel broadly expressed in brain, mediates M-type currents.
B C Schroeder, M Hechenberger, F Weinreich, C Kubisch, T J Jentsch. J Biol Chem 2000
B C Schroeder, M Hechenberger, F Weinreich, C Kubisch, T J Jentsch. J Biol Chem 2000
12
Regulation of Kv7 (KCNQ) K+ channel open probability by phosphatidylinositol 4,5-bisphosphate.
Yang Li, Nikita Gamper, Donald W Hilgemann, Mark S Shapiro. J Neurosci 2005
Yang Li, Nikita Gamper, Donald W Hilgemann, Mark S Shapiro. J Neurosci 2005
11
Heteromeric Kv7.2/7.3 channels differentially regulate action potential initiation and conduction in neocortical myelinated axons.
Arne Battefeld, Baouyen T Tran, Jason Gavrilis, Edward C Cooper, Maarten H P Kole. J Neurosci 2014
Arne Battefeld, Baouyen T Tran, Jason Gavrilis, Edward C Cooper, Maarten H P Kole. J Neurosci 2014
11
M channel KCNQ2 subunits are localized to key sites for control of neuronal network oscillations and synchronization in mouse brain.
E C Cooper, E Harrington, Y N Jan, L Y Jan. J Neurosci 2001
E C Cooper, E Harrington, Y N Jan, L Y Jan. J Neurosci 2001
11
Disruption of the epilepsy KCNQ2 gene results in neural hyperexcitability.
H Watanabe, E Nagata, A Kosakai, M Nakamura, M Yokoyama, K Tanaka, H Sasai. J Neurochem 2000
H Watanabe, E Nagata, A Kosakai, M Nakamura, M Yokoyama, K Tanaka, H Sasai. J Neurochem 2000
11
Clinical spectrum of early onset epileptic encephalopathies caused by KCNQ2 mutation.
Mitsuhiro Kato, Takanori Yamagata, Masaya Kubota, Hiroshi Arai, Sumimasa Yamashita, Taku Nakagawa, Takanari Fujii, Kenji Sugai, Kaoru Imai, Tami Uster,[...]. Epilepsia 2013
Mitsuhiro Kato, Takanori Yamagata, Masaya Kubota, Hiroshi Arai, Sumimasa Yamashita, Taku Nakagawa, Takanari Fujii, Kenji Sugai, Kaoru Imai, Tami Uster,[...]. Epilepsia 2013
11
KCNQ/M currents in sensory neurons: significance for pain therapy.
Gayle M Passmore, Alexander A Selyanko, Mohini Mistry, Mona Al-Qatari, Stephen J Marsh, Elizabeth A Matthews, Anthony H Dickenson, Terry A Brown, Stephen A Burbidge, Martin Main,[...]. J Neurosci 2003
Gayle M Passmore, Alexander A Selyanko, Mohini Mistry, Mona Al-Qatari, Stephen J Marsh, Elizabeth A Matthews, Anthony H Dickenson, Terry A Brown, Stephen A Burbidge, Martin Main,[...]. J Neurosci 2003
11
KCNQ/M-currents contribute to the resting membrane potential in rat visceral sensory neurons.
Cynthia L Wladyka, Diana L Kunze. J Physiol 2006
Cynthia L Wladyka, Diana L Kunze. J Physiol 2006
10
Activation of expressed KCNQ potassium currents and native neuronal M-type potassium currents by the anti-convulsant drug retigabine.
L Tatulian, P Delmas, F C Abogadie, D A Brown. J Neurosci 2001
L Tatulian, P Delmas, F C Abogadie, D A Brown. J Neurosci 2001
10
KCNQ2 encephalopathy: Features, mutational hot spots, and ezogabine treatment of 11 patients.
John J Millichap, Kristen L Park, Tammy Tsuchida, Bruria Ben-Zeev, Lionel Carmant, Robert Flamini, Nishtha Joshi, Paul M Levisohn, Eric Marsh, Srishti Nangia,[...]. Neurol Genet 2016
John J Millichap, Kristen L Park, Tammy Tsuchida, Bruria Ben-Zeev, Lionel Carmant, Robert Flamini, Nishtha Joshi, Paul M Levisohn, Eric Marsh, Srishti Nangia,[...]. Neurol Genet 2016
10
M-type K+ channels in peripheral nociceptive pathways.
Xiaona Du, Haixia Gao, David Jaffe, Hailin Zhang, Nikita Gamper. Br J Pharmacol 2018
Xiaona Du, Haixia Gao, David Jaffe, Hailin Zhang, Nikita Gamper. Br J Pharmacol 2018
28
Suppression of KCNQ/M (Kv7) potassium channels in dorsal root ganglion neurons contributes to the development of bone cancer pain in a rat model.
Qin Zheng, Dong Fang, Min Liu, Jie Cai, You Wan, Ji-Sheng Han, Guo-Gang Xing. Pain 2013
Qin Zheng, Dong Fang, Min Liu, Jie Cai, You Wan, Ji-Sheng Han, Guo-Gang Xing. Pain 2013
13
The KCNQ5 potassium channel mediates a component of the afterhyperpolarization current in mouse hippocampus.
Anastassios V Tzingounis, Matthias Heidenreich, Tatjana Kharkovets, Guillermo Spitzmaul, Henrik S Jensen, Roger A Nicoll, Thomas J Jentsch. Proc Natl Acad Sci U S A 2010
Anastassios V Tzingounis, Matthias Heidenreich, Tatjana Kharkovets, Guillermo Spitzmaul, Henrik S Jensen, Roger A Nicoll, Thomas J Jentsch. Proc Natl Acad Sci U S A 2010
11
KCNQ/M channels control spike afterdepolarization and burst generation in hippocampal neurons.
Cuiyong Yue, Yoel Yaari. J Neurosci 2004
Cuiyong Yue, Yoel Yaari. J Neurosci 2004
9
Moderate loss of function of cyclic-AMP-modulated KCNQ2/KCNQ3 K+ channels causes epilepsy.
B C Schroeder, C Kubisch, V Stein, T J Jentsch. Nature 1998
B C Schroeder, C Kubisch, V Stein, T J Jentsch. Nature 1998
9
Polarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domains.
Hee Jung Chung, Yuh Nung Jan, Lily Y Jan. Proc Natl Acad Sci U S A 2006
Hee Jung Chung, Yuh Nung Jan, Lily Y Jan. Proc Natl Acad Sci U S A 2006
9
Regulation of neural KCNQ channels: signalling pathways, structural motifs and functional implications.
Ciria C Hernandez, Oleg Zaika, Gleb P Tolstykh, Mark S Shapiro. J Physiol 2008
Ciria C Hernandez, Oleg Zaika, Gleb P Tolstykh, Mark S Shapiro. J Physiol 2008
9
Dominant-negative effects of KCNQ2 mutations are associated with epileptic encephalopathy.
Gökce Orhan, Merle Bock, Dorien Schepers, Elena I Ilina, Stephanie Nadine Reichel, Heidi Löffler, Nicole Jezutkovic, Sarah Weckhuysen, Simone Mandelstam, Arvid Suls,[...]. Ann Neurol 2014
Gökce Orhan, Merle Bock, Dorien Schepers, Elena I Ilina, Stephanie Nadine Reichel, Heidi Löffler, Nicole Jezutkovic, Sarah Weckhuysen, Simone Mandelstam, Arvid Suls,[...]. Ann Neurol 2014
9
Driving with no brakes: molecular pathophysiology of Kv7 potassium channels.
Maria Virginia Soldovieri, Francesco Miceli, Maurizio Taglialatela. Physiology (Bethesda) 2011
Maria Virginia Soldovieri, Francesco Miceli, Maurizio Taglialatela. Physiology (Bethesda) 2011
9
Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons.
Brian J Wainger, Evangelos Kiskinis, Cassidy Mellin, Ole Wiskow, Steve S W Han, Jackson Sandoe, Numa P Perez, Luis A Williams, Seungkyu Lee, Gabriella Boulting,[...]. Cell Rep 2014
Brian J Wainger, Evangelos Kiskinis, Cassidy Mellin, Ole Wiskow, Steve S W Han, Jackson Sandoe, Numa P Perez, Luis A Williams, Seungkyu Lee, Gabriella Boulting,[...]. Cell Rep 2014
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A pore mutation in a novel KQT-like potassium channel gene in an idiopathic epilepsy family.
C Charlier, N A Singh, S G Ryan, T B Lewis, B E Reus, R J Leach, M Leppert. Nat Genet 1998
C Charlier, N A Singh, S G Ryan, T B Lewis, B E Reus, R J Leach, M Leppert. Nat Genet 1998
9
KCNQ-Encoded Potassium Channels as Therapeutic Targets.
Vincenzo Barrese, Jennifer B Stott, Iain A Greenwood. Annu Rev Pharmacol Toxicol 2018
Vincenzo Barrese, Jennifer B Stott, Iain A Greenwood. Annu Rev Pharmacol Toxicol 2018
14
KCNQ channel openers reverse depressive symptoms via an active resilience mechanism.
Allyson K Friedman, Barbara Juarez, Stacy M Ku, Hongxing Zhang, Rhodora C Calizo, Jessica J Walsh, Dipesh Chaudhury, Song Zhang, Angel Hawkins, David M Dietz,[...]. Nat Commun 2016
Allyson K Friedman, Barbara Juarez, Stacy M Ku, Hongxing Zhang, Rhodora C Calizo, Jessica J Walsh, Dipesh Chaudhury, Song Zhang, Angel Hawkins, David M Dietz,[...]. Nat Commun 2016
10
Mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions show seizures and neuronal plasticity without synaptic reorganization.
Nanda A Singh, James F Otto, E Jill Dahle, Chris Pappas, Jonathan D Leslie, Alex Vilaythong, Jeffrey L Noebels, H Steve White, Karen S Wilcox, Mark F Leppert. J Physiol 2008
Nanda A Singh, James F Otto, E Jill Dahle, Chris Pappas, Jonathan D Leslie, Alex Vilaythong, Jeffrey L Noebels, H Steve White, Karen S Wilcox, Mark F Leppert. J Physiol 2008
9
Kv7/KCNQ/M-channels in rat glutamatergic hippocampal axons and their role in regulation of excitability and transmitter release.
K Vervaeke, N Gu, C Agdestein, H Hu, J F Storm. J Physiol 2006
K Vervaeke, N Gu, C Agdestein, H Hu, J F Storm. J Physiol 2006
8
Heterozygous loss of epilepsy gene KCNQ2 alters social, repetitive and exploratory behaviors.
Eung Chang Kim, Jaimin Patel, Jiaren Zhang, Heun Soh, Justin S Rhodes, Anastasios V Tzingounis, Hee Jung Chung. Genes Brain Behav 2020
Eung Chang Kim, Jaimin Patel, Jiaren Zhang, Heun Soh, Justin S Rhodes, Anastasios V Tzingounis, Hee Jung Chung. Genes Brain Behav 2020
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Extending the KCNQ2 encephalopathy spectrum: clinical and neuroimaging findings in 17 patients.
Sarah Weckhuysen, Vanja Ivanovic, Rik Hendrickx, Rudy Van Coster, Helle Hjalgrim, Rikke S Møller, Sabine Grønborg, An-Sofie Schoonjans, Berten Ceulemans, Sinead B Heavin,[...]. Neurology 2013
Sarah Weckhuysen, Vanja Ivanovic, Rik Hendrickx, Rudy Van Coster, Helle Hjalgrim, Rikke S Møller, Sabine Grønborg, An-Sofie Schoonjans, Berten Ceulemans, Sinead B Heavin,[...]. Neurology 2013
8
Similar early characteristics but variable neurological outcome of patients with a de novo mutation of KCNQ2.
Mathieu Milh, Nadia Boutry-Kryza, Julie Sutera-Sardo, Cyril Mignot, Stéphane Auvin, Caroline Lacoste, Nathalie Villeneuve, Agathe Roubertie, Bénédicte Heron, Maryline Carneiro,[...]. Orphanet J Rare Dis 2013
Mathieu Milh, Nadia Boutry-Kryza, Julie Sutera-Sardo, Cyril Mignot, Stéphane Auvin, Caroline Lacoste, Nathalie Villeneuve, Agathe Roubertie, Bénédicte Heron, Maryline Carneiro,[...]. Orphanet J Rare Dis 2013
12
Genotype-phenotype correlations in neonatal epilepsies caused by mutations in the voltage sensor of K(v)7.2 potassium channel subunits.
Francesco Miceli, Maria Virginia Soldovieri, Paolo Ambrosino, Vincenzo Barrese, Michele Migliore, Maria Roberta Cilio, Maurizio Taglialatela. Proc Natl Acad Sci U S A 2013
Francesco Miceli, Maria Virginia Soldovieri, Paolo Ambrosino, Vincenzo Barrese, Michele Migliore, Maria Roberta Cilio, Maurizio Taglialatela. Proc Natl Acad Sci U S A 2013
8
XE991 and Linopirdine Are State-Dependent Inhibitors for Kv7/KCNQ Channels that Favor Activated Single Subunits.
Derek L Greene, Seungwoo Kang, Naoto Hoshi. J Pharmacol Exp Ther 2017
Derek L Greene, Seungwoo Kang, Naoto Hoshi. J Pharmacol Exp Ther 2017
30
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.