Robert J Ferrante. Biochim Biophys Acta 2009
Times Cited: 98
Times Cited: 98
Times Cited
Times Co-cited
Similarity
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
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Neuropathological classification of Huntington's disease.
J P Vonsattel, R H Myers, T J Stevens, R J Ferrante, E D Bird, E P Richardson. J Neuropathol Exp Neurol 1985
J P Vonsattel, R H Myers, T J Stevens, R J Ferrante, E D Bird, E P Richardson. J Neuropathol Exp Neurol 1985
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Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease.
Elizabeth J Slow, Jeremy van Raamsdonk, Daniel Rogers, Sarah H Coleman, Rona K Graham, Yu Deng, Rosemary Oh, Nagat Bissada, Sazzad M Hossain, Yu-Zhou Yang,[...]. Hum Mol Genet 2003
Elizabeth J Slow, Jeremy van Raamsdonk, Daniel Rogers, Sarah H Coleman, Rona K Graham, Yu Deng, Rosemary Oh, Nagat Bissada, Sazzad M Hossain, Yu-Zhou Yang,[...]. Hum Mol Genet 2003
24
Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice.
Michelle Gray, Dyna I Shirasaki, Carlos Cepeda, Véronique M André, Brian Wilburn, Xiao-Hong Lu, Jifang Tao, Irene Yamazaki, Shi-Hua Li, Yi E Sun,[...]. J Neurosci 2008
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Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
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The corticostriatal pathway in Huntington's disease.
Carlos Cepeda, Nanping Wu, Véronique M André, Damian M Cummings, Michael S Levine. Prog Neurobiol 2007
Carlos Cepeda, Nanping Wu, Véronique M André, Damian M Cummings, Michael S Levine. Prog Neurobiol 2007
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Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
16
Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats.
Liliana B Menalled, Jessica D Sison, Ioannis Dragatsis, Scott Zeitlin, Marie-Françoise Chesselet. J Comp Neurol 2003
Liliana B Menalled, Jessica D Sison, Ioannis Dragatsis, Scott Zeitlin, Marie-Françoise Chesselet. J Comp Neurol 2003
16
A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.
J G Hodgson, N Agopyan, C A Gutekunst, B R Leavitt, F LePiane, R Singaraja, D J Smith, N Bissada, K McCutcheon, J Nasir,[...]. Neuron 1999
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16
Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin.
G Schilling, M W Becher, A H Sharp, H A Jinnah, K Duan, J A Kotzuk, H H Slunt, T Ratovitski, J K Cooper, N A Jenkins,[...]. Hum Mol Genet 1999
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15
Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice.
G J Klapstein, R S Fisher, H Zanjani, C Cepeda, E S Jokel, M F Chesselet, M S Levine. J Neurophysiol 2001
G J Klapstein, R S Fisher, H Zanjani, C Cepeda, E S Jokel, M F Chesselet, M S Levine. J Neurophysiol 2001
15
Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models.
Liliana Menalled, Bassem F El-Khodor, Monica Patry, Mayte Suárez-Fariñas, Samantha J Orenstein, Benjamin Zahasky, Christina Leahy, Vanessa Wheeler, X William Yang, Marcy MacDonald,[...]. Neurobiol Dis 2009
Liliana Menalled, Bassem F El-Khodor, Monica Patry, Mayte Suárez-Fariñas, Samantha J Orenstein, Benjamin Zahasky, Christina Leahy, Vanessa Wheeler, X William Yang, Marcy MacDonald,[...]. Neurobiol Dis 2009
15
Rodent genetic models of Huntington disease.
Mary Y Heng, Peter J Detloff, Roger L Albin. Neurobiol Dis 2008
Mary Y Heng, Peter J Detloff, Roger L Albin. Neurobiol Dis 2008
14
Huntington's disease: from molecular pathogenesis to clinical treatment.
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
14
Transient and progressive electrophysiological alterations in the corticostriatal pathway in a mouse model of Huntington's disease.
Carlos Cepeda, Raymond S Hurst, Christopher R Calvert, Elizabeth Hernández-Echeagaray, Oanh K Nguyen, Emily Jocoy, Lindsey J Christian, Marjorie A Ariano, Michael S Levine. J Neurosci 2003
Carlos Cepeda, Raymond S Hurst, Christopher R Calvert, Elizabeth Hernández-Echeagaray, Oanh K Nguyen, Emily Jocoy, Lindsey J Christian, Marjorie A Ariano, Michael S Levine. J Neurosci 2003
13
Transgenic rat model of Huntington's disease.
Stephan von Hörsten, Ina Schmitt, Huu Phuc Nguyen, Carsten Holzmann, Thorsten Schmidt, Thomas Walther, Michael Bader, Reinhard Pabst, Philipp Kobbe, Jana Krotova,[...]. Hum Mol Genet 2003
Stephan von Hörsten, Ina Schmitt, Huu Phuc Nguyen, Carsten Holzmann, Thorsten Schmidt, Thomas Walther, Michael Bader, Reinhard Pabst, Philipp Kobbe, Jana Krotova,[...]. Hum Mol Genet 2003
13
Early increase in extrasynaptic NMDA receptor signaling and expression contributes to phenotype onset in Huntington's disease mice.
Austen J Milnerwood, Clare M Gladding, Mahmoud A Pouladi, Alexandra M Kaufman, Rochelle M Hines, Jamie D Boyd, Rebecca W Y Ko, Oana C Vasuta, Rona K Graham, Michael R Hayden,[...]. Neuron 2010
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13
Decreased expression of striatal signaling genes in a mouse model of Huntington's disease.
R Luthi-Carter, A Strand, N L Peters, S M Solano, Z R Hollingsworth, A S Menon, A S Frey, B S Spektor, E B Penney, G Schilling,[...]. Hum Mol Genet 2000
R Luthi-Carter, A Strand, N L Peters, S M Solano, Z R Hollingsworth, A S Menon, A S Frey, B S Spektor, E B Penney, G Schilling,[...]. Hum Mol Genet 2000
13
Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.
Alexander V Panov, Claire-Anne Gutekunst, Blair R Leavitt, Michael R Hayden, James R Burke, Warren J Strittmatter, J Timothy Greenamyre. Nat Neurosci 2002
Alexander V Panov, Claire-Anne Gutekunst, Blair R Leavitt, Michael R Hayden, James R Burke, Warren J Strittmatter, J Timothy Greenamyre. Nat Neurosci 2002
12
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes.
Chiara Zuccato, Marzia Tartari, Andrea Crotti, Donato Goffredo, Marta Valenza, Luciano Conti, Tiziana Cataudella, Blair R Leavitt, Michael R Hayden, Tõnis Timmusk,[...]. Nat Genet 2003
Chiara Zuccato, Marzia Tartari, Andrea Crotti, Donato Goffredo, Marta Valenza, Luciano Conti, Tiziana Cataudella, Blair R Leavitt, Michael R Hayden, Tõnis Timmusk,[...]. Nat Genet 2003
12
Chronology of behavioral symptoms and neuropathological sequela in R6/2 Huntington's disease transgenic mice.
Edward C Stack, James K Kubilus, Karen Smith, Kerry Cormier, Steven J Del Signore, Emmanuel Guelin, Hoon Ryu, Steven M Hersch, Robert J Ferrante. J Comp Neurol 2005
Edward C Stack, James K Kubilus, Karen Smith, Kerry Cormier, Steven J Del Signore, Emmanuel Guelin, Hoon Ryu, Steven M Hersch, Robert J Ferrante. J Comp Neurol 2005
12
Mouse models of Huntington's disease.
Liliana B Menalled, Marie-Françoise Chesselet. Trends Pharmacol Sci 2002
Liliana B Menalled, Marie-Françoise Chesselet. Trends Pharmacol Sci 2002
12
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules.
Laurent R Gauthier, Bénédicte C Charrin, Maria Borrell-Pagès, Jim P Dompierre, Hélène Rangone, Fabrice P Cordelières, Jan De Mey, Marcy E MacDonald, Volkmar Lessmann, Sandrine Humbert,[...]. Cell 2004
Laurent R Gauthier, Bénédicte C Charrin, Maria Borrell-Pagès, Jim P Dompierre, Hélène Rangone, Fabrice P Cordelières, Jan De Mey, Marcy E MacDonald, Volkmar Lessmann, Sandrine Humbert,[...]. Cell 2004
12
Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease.
C Zuccato, A Ciammola, D Rigamonti, B R Leavitt, D Goffredo, L Conti, M E MacDonald, R M Friedlander, V Silani, M R Hayden,[...]. Science 2001
C Zuccato, A Ciammola, D Rigamonti, B R Leavitt, D Goffredo, L Conti, M E MacDonald, R M Friedlander, V Silani, M R Hayden,[...]. Science 2001
12
Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release.
Yeun Su Choo, Gail V W Johnson, Marcy MacDonald, Peter J Detloff, Mathieu Lesort. Hum Mol Genet 2004
Yeun Su Choo, Gail V W Johnson, Marcy MacDonald, Peter J Detloff, Mathieu Lesort. Hum Mol Genet 2004
11
Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity.
F C Nucifora , M Sasaki, M F Peters, H Huang, J K Cooper, M Yamada, H Takahashi, S Tsuji, J Troncoso, V L Dawson,[...]. Science 2001
F C Nucifora , M Sasaki, M F Peters, H Huang, J K Cooper, M Yamada, H Takahashi, S Tsuji, J Troncoso, V L Dawson,[...]. Science 2001
10
Neurological abnormalities in a knock-in mouse model of Huntington's disease.
C H Lin, S Tallaksen-Greene, W M Chien, J A Cearley, W S Jackson, A B Crouse, S Ren, X J Li, R L Albin, P J Detloff. Hum Mol Genet 2001
C H Lin, S Tallaksen-Greene, W M Chien, J A Cearley, W S Jackson, A B Crouse, S Ren, X J Li, R L Albin, P J Detloff. Hum Mol Genet 2001
10
Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease.
A Yamamoto, J J Lucas, R Hen. Cell 2000
A Yamamoto, J J Lucas, R Hen. Cell 2000
10
Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration.
Patrick Weydt, Victor V Pineda, Anne E Torrence, Randell T Libby, Terrence F Satterfield, Eduardo R Lazarowski, Merle L Gilbert, Gregory J Morton, Theodor K Bammler, Andrew D Strand,[...]. Cell Metab 2006
Patrick Weydt, Victor V Pineda, Anne E Torrence, Randell T Libby, Terrence F Satterfield, Eduardo R Lazarowski, Merle L Gilbert, Gregory J Morton, Theodor K Bammler, Andrew D Strand,[...]. Cell Metab 2006
10
The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.
J S Steffan, A Kazantsev, O Spasic-Boskovic, M Greenwald, Y Z Zhu, H Gohler, E E Wanker, G P Bates, D E Housman, L M Thompson. Proc Natl Acad Sci U S A 2000
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10
Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology.
C A Gutekunst, S H Li, H Yi, J S Mulroy, S Kuemmerle, R Jones, D Rye, R J Ferrante, S M Hersch, X J Li. J Neurosci 1999
C A Gutekunst, S H Li, H Yi, J S Mulroy, S Kuemmerle, R Jones, D Rye, R J Ferrante, S M Hersch, X J Li. J Neurosci 1999
10
Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice.
Xiaofeng Gu, Chenjian Li, Weizheng Wei, Victor Lo, Shiaoching Gong, Shi-Hua Li, Takuji Iwasato, Shigeyoshi Itohara, Xiao-Jiang Li, Istvan Mody,[...]. Neuron 2005
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10
Detection of Huntington's disease decades before diagnosis: the Predict-HD study.
J S Paulsen, D R Langbehn, J C Stout, E Aylward, C A Ross, M Nance, M Guttman, S Johnson, M MacDonald, L J Beglinger,[...]. J Neurol Neurosurg Psychiatry 2008
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10
Animal models of Huntington's disease.
Shilpa Ramaswamy, Jodi L McBride, Jeffrey H Kordower. ILAR J 2007
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Differential loss of striatal projection neurons in Huntington disease.
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Role of brain-derived neurotrophic factor in Huntington's disease.
Chiara Zuccato, Elena Cattaneo. Prog Neurobiol 2007
Chiara Zuccato, Elena Cattaneo. Prog Neurobiol 2007
10
Molecular mechanisms and potential therapeutical targets in Huntington's disease.
Chiara Zuccato, Marta Valenza, Elena Cattaneo. Physiol Rev 2010
Chiara Zuccato, Marta Valenza, Elena Cattaneo. Physiol Rev 2010
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Choosing an animal model for the study of Huntington's disease.
Mahmoud A Pouladi, A Jennifer Morton, Michael R Hayden. Nat Rev Neurosci 2013
Mahmoud A Pouladi, A Jennifer Morton, Michael R Hayden. Nat Rev Neurosci 2013
10
The use of the R6 transgenic mouse models of Huntington's disease in attempts to develop novel therapeutic strategies.
Jia Yi Li, Natalija Popovic, Patrik Brundin. NeuroRx 2005
Jia Yi Li, Natalija Popovic, Patrik Brundin. NeuroRx 2005
9
Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease.
Anthone W Dunah, Hyunkyung Jeong, April Griffin, Yong-Man Kim, David G Standaert, Steven M Hersch, M Maral Mouradian, Anne B Young, Naoko Tanese, Dimitri Krainc. Science 2002
Anthone W Dunah, Hyunkyung Jeong, April Griffin, Yong-Man Kim, David G Standaert, Steven M Hersch, M Maral Mouradian, Anne B Young, Naoko Tanese, Dimitri Krainc. Science 2002
9
Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage.
Alexandre Kuhn, Darlene R Goldstein, Angela Hodges, Andrew D Strand, Thierry Sengstag, Charles Kooperberg, Kristina Becanovic, Mahmoud A Pouladi, Kirupa Sathasivam, Jang-Ho J Cha,[...]. Hum Mol Genet 2007
Alexandre Kuhn, Darlene R Goldstein, Angela Hodges, Andrew D Strand, Thierry Sengstag, Charles Kooperberg, Kristina Becanovic, Mahmoud A Pouladi, Kirupa Sathasivam, Jang-Ho J Cha,[...]. Hum Mol Genet 2007
9
Mitochondrial defect in Huntington's disease caudate nucleus.
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9
Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice.
V C Wheeler, J K White, C A Gutekunst, V Vrbanac, M Weaver, X J Li, S H Li, H Yi, J P Vonsattel, J F Gusella,[...]. Hum Mol Genet 2000
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9
Mitochondrial respiration and ATP production are significantly impaired in striatal cells expressing mutant huntingtin.
Tamara Milakovic, Gail V W Johnson. J Biol Chem 2005
Tamara Milakovic, Gail V W Johnson. J Biol Chem 2005
9
Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice.
M A Hickey, A Kosmalska, J Enayati, R Cohen, S Zeitlin, M S Levine, M-F Chesselet. Neuroscience 2008
M A Hickey, A Kosmalska, J Enayati, R Cohen, S Zeitlin, M S Levine, M-F Chesselet. Neuroscience 2008
9
Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.
Libin Cui, Hyunkyung Jeong, Fran Borovecki, Christopher N Parkhurst, Naoko Tanese, Dimitri Krainc. Cell 2006
Libin Cui, Hyunkyung Jeong, Fran Borovecki, Christopher N Parkhurst, Naoko Tanese, Dimitri Krainc. Cell 2006
9
Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease.
Melinda M Zeron, Oskar Hansson, Nansheng Chen, Cheryl L Wellington, Blair R Leavitt, Patrik Brundin, Michael R Hayden, Lynn A Raymond. Neuron 2002
Melinda M Zeron, Oskar Hansson, Nansheng Chen, Cheryl L Wellington, Blair R Leavitt, Patrik Brundin, Michael R Hayden, Lynn A Raymond. Neuron 2002
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.